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The map label for this gene is acnB [H]

Identifier: 91789446

GI number: 91789446

Start: 3795605

End: 3798220

Strand: Reverse

Name: acnB [H]

Synonym: Bpro_3595

Alternate gene names: 91789446

Gene position: 3798220-3795605 (Counterclockwise)

Preceding gene: 91789447

Following gene: 91789444

Centisome position: 73.04

GC content: 62.39

Gene sequence:

>2616_bases
ATGTCGTCCGAGTTCTTGCAAAGCTACCGCAACCATGTCGCCGAGCGCGCCGTTGCGGGCATTCCACCGCTGCCGCTGTC
CGCCCAGCAAACCGGCGAGGTCATTGAACTGCTGAAAAACCCGCCCAAGGGCGAGGAAGCATTTCTGGTTGATCTCATCA
CTCACCGCGTTCCCGCCGGTGTGGATGACGCCGCCAAGGTCAAGGCCAGCTACCTGGCGGCCGTGGCGCATGGCACGGAA
AAATGCGCGCTGATCTCGCGCGAAAAAGCCACGCAATTGCTGGGCACCATGCTGGGCGGCTACAACATCAGCCCGATGAT
TGCGCTGCTTGACGACGCCGAAGACAGTGTGGCCACGCAGGCGGCCAGCGGCCTGAAGAACACCCTGCTGATGTTCGACC
AGTTCCATGACGTCCAGGAAAAATCCGACAAGGGCAACAAATACGCCAAGGCCGTGCTGCAAAGCTGGGCCGACGCCGAA
TGGTTCACCAGCCGCCCCGAGGTGCCTGAATCCATCAAGCTGACCGTGTTCAAGGTGGCCGGGGAAATCAATACTGACGA
CCTGTCACCCGCGCCCGACGCCTGGAGCCGCCCCGATATTCCACTGCATGCGCTGGCCATGCACAAGAATGCCCGTCCTG
GCGTCACGCCCGAAGAAGACGGCAAGCGCGGCCCGGTCAAGTTCATCGAAGAGCTCAAGGCCAAGGGCAACCTGGTGGCC
TATGTGGGCGACGTGGTGGGCACGGGTTCATCGCGCAAGTCAGCGACCAACTCGGTGCTGTGGTGGACCGGCCAGGACAT
CCCCTATGTGCCCAACAAGCGATTTGGCGGCGTCTGCCTGGGCGGCAAGATCGCCCCGATCTTCTACAACACCATGGAAG
ACTCCGGCGCGCTGCCGATCGAGCTCGACGTGAGCCAGATGGCCATGGGCGACGTGATCGAGTTGCGCCCCTACGAAGGC
AAGGCATTGAAAGACGGCAAGGTGATTGCCGAGTTCAAGCTCAAAAGCGATGTGCTGTTTGACGAAGTGCGCGCCGGTGG
CCGCATTCCGCTGATCGTCGGCCGCGGCCTGACCGCCAAGGCGCGTGCGGCGCTGGGCCTGCCCGTGTCTACCCAGTTCC
GCCTGCCGCAAAACCCTGTTGACAGCGGCCGCGGCTTCACGCTGGCGCAAAAAATGGTCGGCCGGGCGGTTGGTCTGCCT
GAAGGCCAGGGTGTGCGTCCTGGTACCTACTGTGAACCCAAGATGACATCTGTCGGTTCGCAGGACACCACCGGCCCGAT
GACGCGCGACGAACTGAAAGACCTGGCTTGCCTGGGCTTCAGTTCCGACCTGGTGATGCAGTCCTTCTGCCACACCGCGG
CCTATCCGAAACCGGTGGACGTGAAGATGCACCACGAGTTGCCTGACTTCATCAGCACGCGAGGCGGCATTTCGCTGCGT
CCCGGCGACGGCATCATCCACAGCTGGCTCAACCGCATGCTGTTGCCCGACACCGTGGGCACCGGCGGCGACAGCCATAC
CCGTTTCCCCATCGGCATCAGCTTCCCCGCGGGTTCCGGCCTCGTGGCTTTCGGCGCCGCCACCGGCGTGATGCCGCTGG
ACATGCCGGAATCGGTGCTGGTCCGCTTCAAGGGCGAAATGCAGCCCGGCATCACGCTGCGCGACCTGGTCAATGCGATC
CCGCTGTACGCCATCAAGGCCGGCTTGCTGACGGTCGCCAAGCAAGGCAAGAAGAACATCTTCTCGGGCCGAATCCTGGA
GATTGAAGGCTTGCCTGACCTGAAGGTGGAGCAGGCGTTTGAACTGAGCGATGCATCGGCCGAGCGCTCCGCCGGCGGTT
GCACGGTGCACCTGAACAAGGAGCCCATCATCGAATACATCACCAGCAACATCACGATGCTGAAATGGATGATTGCGACG
GGTTACTCGGATGTGCGCACCATCAACCGCCGCATCGCCGCCATGGAAGCCTGGCTGGCCGACCCGCAATTGCTCAAAGG
CGATGCGGACGCCGAATACGCCGCCGTGATCGAAATCGACCTGGCCGACATCCACGAACCCATCGTGGCCTGCCCGAACG
ATCCGGACGACGTGAAGACGCTGGCCGACGTGGCGGGCTCCAAGATCGACGAAGTGTTCATCGGTTCCTGCATGACCAAC
ATCGGCCATTTCCGCGCCGCGTCCAAGCTGCTCGAAAACAAGCGCGACATTCCCGTGAAACTCTGGATGGCTCCACCGAC
CAAGATGGATGCCAAGCAGCTGACCGAAGAAGGCCATTACGGCGTGCTGGGTTCTGCCGGCGCGCGCATGGAAATGCCGG
GTTGCAGCCTGTGCATGGGCAACCAGGCGCAGGTGAAAGAGGGCGCGACGGTGTTCTCCACGTCCACCCGCAACTTCCCC
AACCGTCTGGGCAAGAACTCCAATGTGTACCTGGGCTCCGCCGAGCTGGCCGCGATCTGTTCCAAGCTCGGCCGCATCCC
GACCAAGGCCGAGTACATGGCCGACATGGGCGTGTTGACGGCGGCCAGCAGCACCGTGTACCAGTACCTGAACTTTGACA
AGGTCAAGGATTACACGGACATGGCAGACACCGTGAAAGACGGCGTGGCAGCGTAA

Upstream 100 bases:

>100_bases
ACAGGCGGCTTCGGCCGCCCGATAAACATCATTGCCAGTCCCCAAGACCCCACCCGCGATCCCTACGATCCCACGATTTT
TGAATACAGGAGAAACCAGC

Downstream 100 bases:

>100_bases
GACTTTCATTCGCGTTCACCCGGACCCGTTAAAAGGCCTGGAAGGTTCGGCAAAAAGCCCCGCAGCGAAAGTTGCGGGGC
TTTTTCTTTTTGCTTCAAGT

Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase

Products: NA

Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]

Number of amino acids: Translated: 871; Mature: 870

Protein sequence:

>871_residues
MSSEFLQSYRNHVAERAVAGIPPLPLSAQQTGEVIELLKNPPKGEEAFLVDLITHRVPAGVDDAAKVKASYLAAVAHGTE
KCALISREKATQLLGTMLGGYNISPMIALLDDAEDSVATQAASGLKNTLLMFDQFHDVQEKSDKGNKYAKAVLQSWADAE
WFTSRPEVPESIKLTVFKVAGEINTDDLSPAPDAWSRPDIPLHALAMHKNARPGVTPEEDGKRGPVKFIEELKAKGNLVA
YVGDVVGTGSSRKSATNSVLWWTGQDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPIELDVSQMAMGDVIELRPYEG
KALKDGKVIAEFKLKSDVLFDEVRAGGRIPLIVGRGLTAKARAALGLPVSTQFRLPQNPVDSGRGFTLAQKMVGRAVGLP
EGQGVRPGTYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSSDLVMQSFCHTAAYPKPVDVKMHHELPDFISTRGGISLR
PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAATGVMPLDMPESVLVRFKGEMQPGITLRDLVNAI
PLYAIKAGLLTVAKQGKKNIFSGRILEIEGLPDLKVEQAFELSDASAERSAGGCTVHLNKEPIIEYITSNITMLKWMIAT
GYSDVRTINRRIAAMEAWLADPQLLKGDADAEYAAVIEIDLADIHEPIVACPNDPDDVKTLADVAGSKIDEVFIGSCMTN
IGHFRAASKLLENKRDIPVKLWMAPPTKMDAKQLTEEGHYGVLGSAGARMEMPGCSLCMGNQAQVKEGATVFSTSTRNFP
NRLGKNSNVYLGSAELAAICSKLGRIPTKAEYMADMGVLTAASSTVYQYLNFDKVKDYTDMADTVKDGVAA

Sequences:

>Translated_871_residues
MSSEFLQSYRNHVAERAVAGIPPLPLSAQQTGEVIELLKNPPKGEEAFLVDLITHRVPAGVDDAAKVKASYLAAVAHGTE
KCALISREKATQLLGTMLGGYNISPMIALLDDAEDSVATQAASGLKNTLLMFDQFHDVQEKSDKGNKYAKAVLQSWADAE
WFTSRPEVPESIKLTVFKVAGEINTDDLSPAPDAWSRPDIPLHALAMHKNARPGVTPEEDGKRGPVKFIEELKAKGNLVA
YVGDVVGTGSSRKSATNSVLWWTGQDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPIELDVSQMAMGDVIELRPYEG
KALKDGKVIAEFKLKSDVLFDEVRAGGRIPLIVGRGLTAKARAALGLPVSTQFRLPQNPVDSGRGFTLAQKMVGRAVGLP
EGQGVRPGTYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSSDLVMQSFCHTAAYPKPVDVKMHHELPDFISTRGGISLR
PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAATGVMPLDMPESVLVRFKGEMQPGITLRDLVNAI
PLYAIKAGLLTVAKQGKKNIFSGRILEIEGLPDLKVEQAFELSDASAERSAGGCTVHLNKEPIIEYITSNITMLKWMIAT
GYSDVRTINRRIAAMEAWLADPQLLKGDADAEYAAVIEIDLADIHEPIVACPNDPDDVKTLADVAGSKIDEVFIGSCMTN
IGHFRAASKLLENKRDIPVKLWMAPPTKMDAKQLTEEGHYGVLGSAGARMEMPGCSLCMGNQAQVKEGATVFSTSTRNFP
NRLGKNSNVYLGSAELAAICSKLGRIPTKAEYMADMGVLTAASSTVYQYLNFDKVKDYTDMADTVKDGVAA
>Mature_870_residues
SSEFLQSYRNHVAERAVAGIPPLPLSAQQTGEVIELLKNPPKGEEAFLVDLITHRVPAGVDDAAKVKASYLAAVAHGTEK
CALISREKATQLLGTMLGGYNISPMIALLDDAEDSVATQAASGLKNTLLMFDQFHDVQEKSDKGNKYAKAVLQSWADAEW
FTSRPEVPESIKLTVFKVAGEINTDDLSPAPDAWSRPDIPLHALAMHKNARPGVTPEEDGKRGPVKFIEELKAKGNLVAY
VGDVVGTGSSRKSATNSVLWWTGQDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPIELDVSQMAMGDVIELRPYEGK
ALKDGKVIAEFKLKSDVLFDEVRAGGRIPLIVGRGLTAKARAALGLPVSTQFRLPQNPVDSGRGFTLAQKMVGRAVGLPE
GQGVRPGTYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSSDLVMQSFCHTAAYPKPVDVKMHHELPDFISTRGGISLRP
GDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAATGVMPLDMPESVLVRFKGEMQPGITLRDLVNAIP
LYAIKAGLLTVAKQGKKNIFSGRILEIEGLPDLKVEQAFELSDASAERSAGGCTVHLNKEPIIEYITSNITMLKWMIATG
YSDVRTINRRIAAMEAWLADPQLLKGDADAEYAAVIEIDLADIHEPIVACPNDPDDVKTLADVAGSKIDEVFIGSCMTNI
GHFRAASKLLENKRDIPVKLWMAPPTKMDAKQLTEEGHYGVLGSAGARMEMPGCSLCMGNQAQVKEGATVFSTSTRNFPN
RLGKNSNVYLGSAELAAICSKLGRIPTKAEYMADMGVLTAASSTVYQYLNFDKVKDYTDMADTVKDGVAA

Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]

COG id: COG1049

COG function: function code C; Aconitase B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aconitase/IPM isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367097, Length=864, Percent_Identity=71.412037037037, Blast_Score=1243, Evalue=0.0,
Organism=Escherichia coli, GI1786259, Length=368, Percent_Identity=25.5434782608696, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015931
- InterPro:   IPR015937
- InterPro:   IPR001030
- InterPro:   IPR015928
- InterPro:   IPR015932
- InterPro:   IPR018136
- InterPro:   IPR004406
- InterPro:   IPR015930
- InterPro:   IPR015933
- InterPro:   IPR015929 [H]

Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]

EC number: =4.2.1.3; =4.2.1.99 [H]

Molecular weight: Translated: 93697; Mature: 93566

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00450 ACONITASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEFLQSYRNHVAERAVAGIPPLPLSAQQTGEVIELLKNPPKGEEAFLVDLITHRVPAG
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
VDDAAKVKASYLAAVAHGTEKCALISREKATQLLGTMLGGYNISPMIALLDDAEDSVATQ
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHH
AASGLKNTLLMFDQFHDVQEKSDKGNKYAKAVLQSWADAEWFTSRPEVPESIKLTVFKVA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEE
GEINTDDLSPAPDAWSRPDIPLHALAMHKNARPGVTPEEDGKRGPVKFIEELKAKGNLVA
CCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
YVGDVVGTGSSRKSATNSVLWWTGQDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPI
EECHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCCCCEE
ELDVSQMAMGDVIELRPYEGKALKDGKVIAEFKLKSDVLFDEVRAGGRIPLIVGRGLTAK
EECHHHHHHCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCHH
ARAALGLPVSTQFRLPQNPVDSGRGFTLAQKMVGRAVGLPEGQGVRPGTYCEPKMTSVGS
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC
QDTTGPMTRDELKDLACLGFSSDLVMQSFCHTAAYPKPVDVKMHHELPDFISTRGGISLR
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCEEC
PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAATGVMPLDMPESVL
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHH
VRFKGEMQPGITLRDLVNAIPLYAIKAGLLTVAKQGKKNIFSGRILEIEGLPDLKVEQAF
HEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHH
ELSDASAERSAGGCTVHLNKEPIIEYITSNITMLKWMIATGYSDVRTINRRIAAMEAWLA
CCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
DPQLLKGDADAEYAAVIEIDLADIHEPIVACPNDPDDVKTLADVAGSKIDEVFIGSCMTN
CCHHCCCCCCCCEEEEEEEEHHHCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
IGHFRAASKLLENKRDIPVKLWMAPPTKMDAKQLTEEGHYGVLGSAGARMEMPGCSLCMG
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECCCCEECCCCCCEECC
NQAQVKEGATVFSTSTRNFPNRLGKNSNVYLGSAELAAICSKLGRIPTKAEYMADMGVLT
CCHHHHCCCEEEECCCCCHHHHHCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHH
AASSTVYQYLNFDKVKDYTDMADTVKDGVAA
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSEFLQSYRNHVAERAVAGIPPLPLSAQQTGEVIELLKNPPKGEEAFLVDLITHRVPAG
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
VDDAAKVKASYLAAVAHGTEKCALISREKATQLLGTMLGGYNISPMIALLDDAEDSVATQ
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHH
AASGLKNTLLMFDQFHDVQEKSDKGNKYAKAVLQSWADAEWFTSRPEVPESIKLTVFKVA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEE
GEINTDDLSPAPDAWSRPDIPLHALAMHKNARPGVTPEEDGKRGPVKFIEELKAKGNLVA
CCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
YVGDVVGTGSSRKSATNSVLWWTGQDIPYVPNKRFGGVCLGGKIAPIFYNTMEDSGALPI
EECHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCCCCEE
ELDVSQMAMGDVIELRPYEGKALKDGKVIAEFKLKSDVLFDEVRAGGRIPLIVGRGLTAK
EECHHHHHHCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCHH
ARAALGLPVSTQFRLPQNPVDSGRGFTLAQKMVGRAVGLPEGQGVRPGTYCEPKMTSVGS
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC
QDTTGPMTRDELKDLACLGFSSDLVMQSFCHTAAYPKPVDVKMHHELPDFISTRGGISLR
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCEEC
PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFGAATGVMPLDMPESVL
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHH
VRFKGEMQPGITLRDLVNAIPLYAIKAGLLTVAKQGKKNIFSGRILEIEGLPDLKVEQAF
HEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHH
ELSDASAERSAGGCTVHLNKEPIIEYITSNITMLKWMIATGYSDVRTINRRIAAMEAWLA
CCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
DPQLLKGDADAEYAAVIEIDLADIHEPIVACPNDPDDVKTLADVAGSKIDEVFIGSCMTN
CCHHCCCCCCCCEEEEEEEEHHHCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
IGHFRAASKLLENKRDIPVKLWMAPPTKMDAKQLTEEGHYGVLGSAGARMEMPGCSLCMG
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECCCCEECCCCCCEECC
NQAQVKEGATVFSTSTRNFPNRLGKNSNVYLGSAELAAICSKLGRIPTKAEYMADMGVLT
CCHHHHCCCEEEECCCCCHHHHHCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHH
AASSTVYQYLNFDKVKDYTDMADTVKDGVAA
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]