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The map label for this gene is gbpR [H]

Identifier: 91789428

GI number: 91789428

Start: 3774334

End: 3775404

Strand: Reverse

Name: gbpR [H]

Synonym: Bpro_3574

Alternate gene names: 91789428

Gene position: 3775404-3774334 (Counterclockwise)

Preceding gene: 91789435

Following gene: 91789425

Centisome position: 72.6

GC content: 65.36

Gene sequence:

>1071_bases
ATGGCCCAGATTGACCGTGTCCTTCGCTCCAACATCAAACTGCGCCACCTGCAACTGATGGTGGCGCTGGACCAGTTTCG
CCATCTGGGCCGAACGGCCGAGTTCCTGTCGGTCAGCCAGCCGGCCGTCTCGAAAATGCTCACCGAGGTCGAGAGCATGC
TCGACCTGACGCTGTTTGAGCGCTCCACGCGCGGCACGGTTCCCACATCCAGCGGCCAGGCCATCGTGCGTTTTGCGCGC
TCGGTGCTGGCGGAATACGAACGCACGCGCGATGAAATTGCAGCGGTGGCCAGCGGGGCGGCGGGCCGCACCCGCGTTGG
TGCCATGGTGGTGGCCATGCCGGTCCTGCTGGCCGGTGCGGTCAAGTTGCTCAAGCAGCGTTCGGCGCAGGCCACGGTGC
TGGTGGAGGAGGGCGACCTCACGCACCTGCTGCCCAAACTGCGCCTGGGCGAACTGGACCTGTTTGTCGGCCGGCTGGAG
CCTGGCTACGCCGCGCCGGACCTGGTGACCGAGGCGCTGTTCAACGAACCGATGAAGGTGGTGGTCAGGCGCGGCCATGC
CCTGGCGCGGCGCAAAACCCCGGGCTGGGCCGATCTGGCCGCCATGCCCTGCGTATTGCCGCCGCCCTGGGCTTCACTGC
GTGTGAAGATCGAGCAGACTTTCTTTCGCCACGGGCTGAACCCGCCGGTCGATATTGTCGAGACCTCGTCCTTCCTGGTG
CTCAGCACTTTTGTGCAGCAGCGCGAGGCGGCCGGTTTCCTGGCGCGCTCGGTGGCCCTGCACTTCGAGAGGGAGGGCCT
GTTTGACATTTTGCCCATCGAGGTACCGATTGAGCTGCCCCCCATCGGCCTCATCACCGTGCGGGGGCGGCGGCTGACGC
CGAGCAGTGAGCAATTGATGGACTGTTTGCGCCTGGTCGCCGAAGACGTTCACAACGAAGAGAGTCAGACGCCGGGCCAG
AAATCGACACGGGCCGCGGTGCTTAAGCCGGCACAGAAGCTGGCAAAGAAAGGGAGCAAGCAAGCCAGTAGCGCCAGGAG
TGCCAGGAGTGCCAAGGCAACTGGCGCGTGA

Upstream 100 bases:

>100_bases
CGTCTTATGCCGCGTCTTATGCAGCGATTCTTGCCCGATTCTTCATAACAATCTAATCGAATAGTGGAATAGCTTCATAG
CCTCTGGGTTAATATGAACC

Downstream 100 bases:

>100_bases
TAGCGGCGTACCGGGCTTCGCGCGGTTCCGCTGCGCTATCGAGTCAATTCACCTCTACCGCAAACAGCCCGCCCGACCAC
GGCGCGATGGCCAATGCATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAQIDRVLRSNIKLRHLQLMVALDQFRHLGRTAEFLSVSQPAVSKMLTEVESMLDLTLFERSTRGTVPTSSGQAIVRFAR
SVLAEYERTRDEIAAVASGAAGRTRVGAMVVAMPVLLAGAVKLLKQRSAQATVLVEEGDLTHLLPKLRLGELDLFVGRLE
PGYAAPDLVTEALFNEPMKVVVRRGHALARRKTPGWADLAAMPCVLPPPWASLRVKIEQTFFRHGLNPPVDIVETSSFLV
LSTFVQQREAAGFLARSVALHFEREGLFDILPIEVPIELPPIGLITVRGRRLTPSSEQLMDCLRLVAEDVHNEESQTPGQ
KSTRAAVLKPAQKLAKKGSKQASSARSARSAKATGA

Sequences:

>Translated_356_residues
MAQIDRVLRSNIKLRHLQLMVALDQFRHLGRTAEFLSVSQPAVSKMLTEVESMLDLTLFERSTRGTVPTSSGQAIVRFAR
SVLAEYERTRDEIAAVASGAAGRTRVGAMVVAMPVLLAGAVKLLKQRSAQATVLVEEGDLTHLLPKLRLGELDLFVGRLE
PGYAAPDLVTEALFNEPMKVVVRRGHALARRKTPGWADLAAMPCVLPPPWASLRVKIEQTFFRHGLNPPVDIVETSSFLV
LSTFVQQREAAGFLARSVALHFEREGLFDILPIEVPIELPPIGLITVRGRRLTPSSEQLMDCLRLVAEDVHNEESQTPGQ
KSTRAAVLKPAQKLAKKGSKQASSARSARSAKATGA
>Mature_355_residues
AQIDRVLRSNIKLRHLQLMVALDQFRHLGRTAEFLSVSQPAVSKMLTEVESMLDLTLFERSTRGTVPTSSGQAIVRFARS
VLAEYERTRDEIAAVASGAAGRTRVGAMVVAMPVLLAGAVKLLKQRSAQATVLVEEGDLTHLLPKLRLGELDLFVGRLEP
GYAAPDLVTEALFNEPMKVVVRRGHALARRKTPGWADLAAMPCVLPPPWASLRVKIEQTFFRHGLNPPVDIVETSSFLVL
STFVQQREAAGFLARSVALHFEREGLFDILPIEVPIELPPIGLITVRGRRLTPSSEQLMDCLRLVAEDVHNEESQTPGQK
STRAAVLKPAQKLAKKGSKQASSARSARSAKATGA

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=300, Percent_Identity=26, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=27.2108843537415, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787601, Length=199, Percent_Identity=25.6281407035176, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789506, Length=233, Percent_Identity=25.3218884120172, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=27.0916334661355, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787879, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=217, Percent_Identity=24.8847926267281, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=207, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38900; Mature: 38769

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIDRVLRSNIKLRHLQLMVALDQFRHLGRTAEFLSVSQPAVSKMLTEVESMLDLTLFE
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RSTRGTVPTSSGQAIVRFARSVLAEYERTRDEIAAVASGAAGRTRVGAMVVAMPVLLAGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VKLLKQRSAQATVLVEEGDLTHLLPKLRLGELDLFVGRLEPGYAAPDLVTEALFNEPMKV
HHHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHEEECCCCCCCCHHHHHHHHHCCHHHH
VVRRGHALARRKTPGWADLAAMPCVLPPPWASLRVKIEQTFFRHGLNPPVDIVETSSFLV
HHHHCHHHHHCCCCCCHHHHHCCCCCCCCCHHHEEHHHHHHHHCCCCCCCHHHCCCHHHH
LSTFVQQREAAGFLARSVALHFEREGLFDILPIEVPIELPPIGLITVRGRRLTPSSEQLM
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCEEEECCCCCCCCHHHHH
DCLRLVAEDVHNEESQTPGQKSTRAAVLKPAQKLAKKGSKQASSARSARSAKATGA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQIDRVLRSNIKLRHLQLMVALDQFRHLGRTAEFLSVSQPAVSKMLTEVESMLDLTLFE
CHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RSTRGTVPTSSGQAIVRFARSVLAEYERTRDEIAAVASGAAGRTRVGAMVVAMPVLLAGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VKLLKQRSAQATVLVEEGDLTHLLPKLRLGELDLFVGRLEPGYAAPDLVTEALFNEPMKV
HHHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHEEECCCCCCCCHHHHHHHHHCCHHHH
VVRRGHALARRKTPGWADLAAMPCVLPPPWASLRVKIEQTFFRHGLNPPVDIVETSSFLV
HHHHCHHHHHCCCCCCHHHHHCCCCCCCCCHHHEEHHHHHHHHCCCCCCCHHHCCCHHHH
LSTFVQQREAAGFLARSVALHFEREGLFDILPIEVPIELPPIGLITVRGRRLTPSSEQLM
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCEEEECCCCCCCCHHHHH
DCLRLVAEDVHNEESQTPGQKSTRAAVLKPAQKLAKKGSKQASSARSARSAKATGA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]