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The map label for this gene is bepF [H]

Identifier: 91789284

GI number: 91789284

Start: 3630047

End: 3631282

Strand: Reverse

Name: bepF [H]

Synonym: Bpro_3429

Alternate gene names: 91789284

Gene position: 3631282-3630047 (Counterclockwise)

Preceding gene: 91789285

Following gene: 91789283

Centisome position: 69.83

GC content: 67.56

Gene sequence:

>1236_bases
ATGCCATCGATTCAATTACCGGCCAACAAGCGCCGACTTCTGGCCGTTGCTCTGGCCGTGCTGGCCGTCATCGGCATTTC
TGCCGTCGTCTTCGGCGTGTCCAGCCCGCGCGCCCAGCCCGGGGCCGCGGTCGAGCCGCCCGCCACCCCGGTGTCGGTGG
CGACTGTCGTGCAGAGCGACGTGGCCGCCTGGGACGAGTTTTCCGGCCGGCTGGAAGCCGTCGAGCGGGTGGACATCCGT
TCGCGCGTGGCCGGCACCATCCAGGCCGTGCATTTCCGCGAAGGTGCGCTGGTCAAAAAGGGCGACCTGCTGCTGACGAT
TGACCCGGCCCCTTATGCCGCCGATGTGGAGCGTGCCGATGCGCAGGTTGCTGCGGCCCAGGCCCGGGTCACCCAGGCCA
AAGGCGAGCAGGAGCGCTCGCAGCGCCTGTGGAGCGAGCAGGCCATCTCCAAGCGTGAGTTTGACGAGCGCACCAATGGC
AAGGGCGAAGCAGACGCCAACCTGCGTGCCGCGCAGGCGGCCCTGCAGACGGCGCAACTGAGCCTGGGCTACACCCAGGT
GCGCGCGCCGGTCTCCGGGCGGGTCGGCAAGCTCGAAGTCACCGTGGGCAACCTGGTCGCCGCGGGCCCCGGCGCTCCCG
TGCTGACCACGCTGGTGTCCGTGAGCCCCATCTACGCCAGTTTTGACGCCGACGAGCAGGTGGTAGCCAAGGCGCTGAAA
GATGTGCAGGGCAGTGGCGCTGGCAGCAGTGGCCGAAACCTGGAACGCATTCCCGTGCAGATGGGCACTGCGGCCAGCAC
CGACACACCATTTGAAGGCCGGCTGCAGCTGGTCGACAACCAGGTCGATGCGAAGAGCGGCACGGTGCGCGCGCGCGCTG
TGTTTGACAACAAGGATGGCCAGCTCATGCCCGGCCAGTTCGCGCGCATTCGCATGGGCCAGGCCAGCAAAGGCACGGCC
TTGCTGATCAACGAACGCGCCGTCGGCACGGACCAGAACAAGAAATTCGTGCTGGTGGTGGGCGCCGACAACAAGGCGGT
GTACCGCGAGGTCACGCTGGGCGCTTCCATCAACGGCCTGCGCGTGGTCAAGGGCGGCCTGGTGGCCAACGAACGCATCG
TCGTCAATGGCTTGCAGCGTATCCGCCCGGGCGCGCTGGTGGCGCCGCAACCGGTGGAGATGTCCGCCAAGACGGAGCTC
AACGCCAAACCGGTGCAGGTAGCAGCCAAGTCCTGA

Upstream 100 bases:

>100_bases
TTTCGCCGGCACCCCTGCGCTGCAGGCCGGGCACACCCATTCGTCTTCCGTTTCCTGAATCCGTTTTCTTTCTTTGTTTT
TTTTGAGGGAGTTCACCACC

Downstream 100 bases:

>100_bases
GCGGCTGAAAACTGAAAAAAGAACATCGTATGAATCTCTCCAAATTTTCATCGACCGGCCGATCTTTGCCGGCGTGCTGT
CGCTGCTCATGCTCATCTCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPSIQLPANKRRLLAVALAVLAVIGISAVVFGVSSPRAQPGAAVEPPATPVSVATVVQSDVAAWDEFSGRLEAVERVDIR
SRVAGTIQAVHFREGALVKKGDLLLTIDPAPYAADVERADAQVAAAQARVTQAKGEQERSQRLWSEQAISKREFDERTNG
KGEADANLRAAQAALQTAQLSLGYTQVRAPVSGRVGKLEVTVGNLVAAGPGAPVLTTLVSVSPIYASFDADEQVVAKALK
DVQGSGAGSSGRNLERIPVQMGTAASTDTPFEGRLQLVDNQVDAKSGTVRARAVFDNKDGQLMPGQFARIRMGQASKGTA
LLINERAVGTDQNKKFVLVVGADNKAVYREVTLGASINGLRVVKGGLVANERIVVNGLQRIRPGALVAPQPVEMSAKTEL
NAKPVQVAAKS

Sequences:

>Translated_411_residues
MPSIQLPANKRRLLAVALAVLAVIGISAVVFGVSSPRAQPGAAVEPPATPVSVATVVQSDVAAWDEFSGRLEAVERVDIR
SRVAGTIQAVHFREGALVKKGDLLLTIDPAPYAADVERADAQVAAAQARVTQAKGEQERSQRLWSEQAISKREFDERTNG
KGEADANLRAAQAALQTAQLSLGYTQVRAPVSGRVGKLEVTVGNLVAAGPGAPVLTTLVSVSPIYASFDADEQVVAKALK
DVQGSGAGSSGRNLERIPVQMGTAASTDTPFEGRLQLVDNQVDAKSGTVRARAVFDNKDGQLMPGQFARIRMGQASKGTA
LLINERAVGTDQNKKFVLVVGADNKAVYREVTLGASINGLRVVKGGLVANERIVVNGLQRIRPGALVAPQPVEMSAKTEL
NAKPVQVAAKS
>Mature_410_residues
PSIQLPANKRRLLAVALAVLAVIGISAVVFGVSSPRAQPGAAVEPPATPVSVATVVQSDVAAWDEFSGRLEAVERVDIRS
RVAGTIQAVHFREGALVKKGDLLLTIDPAPYAADVERADAQVAAAQARVTQAKGEQERSQRLWSEQAISKREFDERTNGK
GEADANLRAAQAALQTAQLSLGYTQVRAPVSGRVGKLEVTVGNLVAAGPGAPVLTTLVSVSPIYASFDADEQVVAKALKD
VQGSGAGSSGRNLERIPVQMGTAASTDTPFEGRLQLVDNQVDAKSGTVRARAVFDNKDGQLMPGQFARIRMGQASKGTAL
LINERAVGTDQNKKFVLVVGADNKAVYREVTLGASINGLRVVKGGLVANERIVVNGLQRIRPGALVAPQPVEMSAKTELN
AKPVQVAAKS

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=385, Percent_Identity=31.9480519480519, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87082036, Length=341, Percent_Identity=32.258064516129, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786668, Length=385, Percent_Identity=34.5454545454545, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789665, Length=367, Percent_Identity=30.2452316076294, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87081951, Length=157, Percent_Identity=38.2165605095541, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081796, Length=338, Percent_Identity=26.6272189349112, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789637, Length=133, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43098; Mature: 42966

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSIQLPANKRRLLAVALAVLAVIGISAVVFGVSSPRAQPGAAVEPPATPVSVATVVQSD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
VAAWDEFSGRLEAVERVDIRSRVAGTIQAVHFREGALVKKGDLLLTIDPAPYAADVERAD
HHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCEEEEECCCCCCCCHHHHH
AQVAAAQARVTQAKGEQERSQRLWSEQAISKREFDERTNGKGEADANLRAAQAALQTAQL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SLGYTQVRAPVSGRVGKLEVTVGNLVAAGPGAPVLTTLVSVSPIYASFDADEQVVAKALK
HCCHHHEECCCCCCCEEEEEEECCEEECCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHH
DVQGSGAGSSGRNLERIPVQMGTAASTDTPFEGRLQLVDNQVDAKSGTVRARAVFDNKDG
HHCCCCCCCCCCCCEECCEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCC
QLMPGQFARIRMGQASKGTALLINERAVGTDQNKKFVLVVGADNKAVYREVTLGASINGL
CCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCE
RVVKGGLVANERIVVNGLQRIRPGALVAPQPVEMSAKTELNAKPVQVAAKS
EEEECCEEECCEEEEECHHHCCCCCEECCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
PSIQLPANKRRLLAVALAVLAVIGISAVVFGVSSPRAQPGAAVEPPATPVSVATVVQSD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
VAAWDEFSGRLEAVERVDIRSRVAGTIQAVHFREGALVKKGDLLLTIDPAPYAADVERAD
HHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCCEEEEECCCCCCCCHHHHH
AQVAAAQARVTQAKGEQERSQRLWSEQAISKREFDERTNGKGEADANLRAAQAALQTAQL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SLGYTQVRAPVSGRVGKLEVTVGNLVAAGPGAPVLTTLVSVSPIYASFDADEQVVAKALK
HCCHHHEECCCCCCCEEEEEEECCEEECCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHH
DVQGSGAGSSGRNLERIPVQMGTAASTDTPFEGRLQLVDNQVDAKSGTVRARAVFDNKDG
HHCCCCCCCCCCCCEECCEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCC
QLMPGQFARIRMGQASKGTALLINERAVGTDQNKKFVLVVGADNKAVYREVTLGASINGL
CCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCE
RVVKGGLVANERIVVNGLQRIRPGALVAPQPVEMSAKTELNAKPVQVAAKS
EEEECCEEECCEEEEECHHHCCCCCEECCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]