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The map label for this gene is ggt [H]

Identifier: 91788954

GI number: 91788954

Start: 3261982

End: 3263847

Strand: Direct

Name: ggt [H]

Synonym: Bpro_3094

Alternate gene names: 91788954

Gene position: 3261982-3263847 (Clockwise)

Preceding gene: 91788953

Following gene: 91788956

Centisome position: 62.73

GC content: 64.58

Gene sequence:

>1866_bases
ATGACTCCCACTCCTGCACGAACGCACTCCGCTTTCCAACTGCTTGCAGCCGCATTTGCCACAATCCTGCTGGTGGCCGG
TTGCGCATCGCCGCCCCCGTTTGCCTACAGCGTGCCCCTACAGCCCGAAAGCGCCTCGGGTTACACCGAAAAACCCGGCT
GGGCGACCTCGAAATTTGCGGTCGCCGCGGCCAATCCGCTGGCCACCGATGCCGGCTACCAGGTGCTCAAGGCCGGCGGT
TCGGCAATTGACGCCGCCATAGCGGTGCAGATGGTCCTGACCCTGGTCGAACCGCAGTCCAGCGGCATAGGCGGCGGCGC
TTTCCTGCTCCATTACAACGGCAAGGCGGTCGAGGCTTTTGATGGCCGCGAGACCGCACCTGCGGCGGTGGACGAAAAAC
TCTTTCTCGGTGCCGATGGCAAACCCATGGCTTTTTACGACGGTGTAGTCGGTGGCCGCTCTGTCGGTGTGCCGGGCACG
GTGCGCATGCTGGAGATGGCGCACAAGCAGTACGGCAAACTGCCCTGGGCCCAGTTGTTCGCACCGGCCATCACCTTGGC
CGAAGGCGGCTTCAAGGTCAGCGCACGGCTGGCCACCCAGCTCAAAAACGATCAGCACCTGAAAAAAGACCCGGTAGCCG
CCGCCTATTTCTACCAGGCCAACGGCGAACCGCTGGATGCGGGGTTCACGCTGCGCAACCAGCCGCTGGCCAATGTGCTG
AAAAAAATCGCCGCCAGCGGCTCCAAAGGCCTGCTCGAAGGCGACGTTGCCCAGGCCATCGTCAGCAAGGTGCAAAACCA
CCCGACCAACCCCGGCAAACTCAGCCTGGCCGATCTGGCGGGCTACCAGGCCAAAAAACGCGATCCGATCTGCCACGACT
ACCAGGCCCAAGCCAGGGACTACCGCATCTGCGGCATGCCGCCGCCCAGTTCGGGGGCGATTGCCGTCGGGCAGATTCTC
GGCATCCTGAACAACACCAACGCGGCGACCCTGGCGCTGGACACCGGCATGGGCGGCATACCCGGCAGCACAGGCGCCGC
GCCCTCGGCCGACTGGCTGCATCTGTACACCGAGGCGTCGCGCCTGGCCTTTGCCGACCGCGCGCAGTATCTGGGCGACC
CCGACTTTGTGCAGCCGCCGGCCGGCAGCTGGACGAGCCTGCTGGCACCAGCCTACCTGGCCGACCGCGCAAAACTGATT
GCCGCACAGCCCGGCGGGCAAAGCATGAAAGTCGCCAAGCCGGGTTCCCCCGGCGGCATGAGGGCCGCGTATGCACCGAT
GCCCGAGCAGCCCGAGTACGGCACCTCGCACATCAGCATCGTCGATGCTTATGGCAACGCCATTGCGATGACCACGACGA
TTGAAGACCAGTTCGGCGCGCGCCAGATGGTCAATGGTTTTCTTTTGAACAATGAGCTGACCGACTTTAGCTATGCCCCC
ACCGACGCCGCTGGCAAGCCGGTGGCGAACCGCGTGCAGCCCGGCAAACGCCCGCGCTCATCAATGGCACCCACCCTGGT
GTTTGAAAAAATCACCGGTCAGCTGGTGATGAGCGGCGGCAGTTCGGGCGGTGCGCTGATCATTCACGACATCGTCAAAA
CGCTGTACGGCGTACTGCACTGGGGCCTGCTGCCGCAGCAGGCGATTGACCTGCCCAACTTTGGCTCGCTCAATGGACCC
AGCCTGCTGGAAGAAAAGCGTTTCGCACCCGCCACCGTTGAGGCCTTGAGGGCACGCGGCGCCGAGGTGCGCGAAATGAA
CATGACCAGCGGCTTGCAGGCCATCGCGCGCGGCCAGGCCCATGGCACGCCGGTGTGGCTGGGCGGCGCCGATCCGCGCC
GAGAAGGCGTGGTGATGGGGGATTAG

Upstream 100 bases:

>100_bases
TTTTTCCGCTGCTTACAAATCACCTGCGGCTGCGTACATTTCATTGCGGCGCCTGGACTGGCCTGGATTTAACATGGCAC
GAATTATCAAAGGAGCAGCA

Downstream 100 bases:

>100_bases
CCCCCACGCTTGCCACTGCGTGTGCCTGCGGCGTTGCGCTGCCCCTTGCACGAGAAAAAGGGGCTGTGCTTGCTCGGGGC
GGCCTTCGCAGCGCACCAGT

Product: gamma-glutamyltransferase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTPTPARTHSAFQLLAAAFATILLVAGCASPPPFAYSVPLQPESASGYTEKPGWATSKFAVAAANPLATDAGYQVLKAGG
SAIDAAIAVQMVLTLVEPQSSGIGGGAFLLHYNGKAVEAFDGRETAPAAVDEKLFLGADGKPMAFYDGVVGGRSVGVPGT
VRMLEMAHKQYGKLPWAQLFAPAITLAEGGFKVSARLATQLKNDQHLKKDPVAAAYFYQANGEPLDAGFTLRNQPLANVL
KKIAASGSKGLLEGDVAQAIVSKVQNHPTNPGKLSLADLAGYQAKKRDPICHDYQAQARDYRICGMPPPSSGAIAVGQIL
GILNNTNAATLALDTGMGGIPGSTGAAPSADWLHLYTEASRLAFADRAQYLGDPDFVQPPAGSWTSLLAPAYLADRAKLI
AAQPGGQSMKVAKPGSPGGMRAAYAPMPEQPEYGTSHISIVDAYGNAIAMTTTIEDQFGARQMVNGFLLNNELTDFSYAP
TDAAGKPVANRVQPGKRPRSSMAPTLVFEKITGQLVMSGGSSGGALIIHDIVKTLYGVLHWGLLPQQAIDLPNFGSLNGP
SLLEEKRFAPATVEALRARGAEVREMNMTSGLQAIARGQAHGTPVWLGGADPRREGVVMGD

Sequences:

>Translated_621_residues
MTPTPARTHSAFQLLAAAFATILLVAGCASPPPFAYSVPLQPESASGYTEKPGWATSKFAVAAANPLATDAGYQVLKAGG
SAIDAAIAVQMVLTLVEPQSSGIGGGAFLLHYNGKAVEAFDGRETAPAAVDEKLFLGADGKPMAFYDGVVGGRSVGVPGT
VRMLEMAHKQYGKLPWAQLFAPAITLAEGGFKVSARLATQLKNDQHLKKDPVAAAYFYQANGEPLDAGFTLRNQPLANVL
KKIAASGSKGLLEGDVAQAIVSKVQNHPTNPGKLSLADLAGYQAKKRDPICHDYQAQARDYRICGMPPPSSGAIAVGQIL
GILNNTNAATLALDTGMGGIPGSTGAAPSADWLHLYTEASRLAFADRAQYLGDPDFVQPPAGSWTSLLAPAYLADRAKLI
AAQPGGQSMKVAKPGSPGGMRAAYAPMPEQPEYGTSHISIVDAYGNAIAMTTTIEDQFGARQMVNGFLLNNELTDFSYAP
TDAAGKPVANRVQPGKRPRSSMAPTLVFEKITGQLVMSGGSSGGALIIHDIVKTLYGVLHWGLLPQQAIDLPNFGSLNGP
SLLEEKRFAPATVEALRARGAEVREMNMTSGLQAIARGQAHGTPVWLGGADPRREGVVMGD
>Mature_620_residues
TPTPARTHSAFQLLAAAFATILLVAGCASPPPFAYSVPLQPESASGYTEKPGWATSKFAVAAANPLATDAGYQVLKAGGS
AIDAAIAVQMVLTLVEPQSSGIGGGAFLLHYNGKAVEAFDGRETAPAAVDEKLFLGADGKPMAFYDGVVGGRSVGVPGTV
RMLEMAHKQYGKLPWAQLFAPAITLAEGGFKVSARLATQLKNDQHLKKDPVAAAYFYQANGEPLDAGFTLRNQPLANVLK
KIAASGSKGLLEGDVAQAIVSKVQNHPTNPGKLSLADLAGYQAKKRDPICHDYQAQARDYRICGMPPPSSGAIAVGQILG
ILNNTNAATLALDTGMGGIPGSTGAAPSADWLHLYTEASRLAFADRAQYLGDPDFVQPPAGSWTSLLAPAYLADRAKLIA
AQPGGQSMKVAKPGSPGGMRAAYAPMPEQPEYGTSHISIVDAYGNAIAMTTTIEDQFGARQMVNGFLLNNELTDFSYAPT
DAAGKPVANRVQPGKRPRSSMAPTLVFEKITGQLVMSGGSSGGALIIHDIVKTLYGVLHWGLLPQQAIDLPNFGSLNGPS
LLEEKRFAPATVEALRARGAEVREMNMTSGLQAIARGQAHGTPVWLGGADPRREGVVMGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=571, Percent_Identity=30.8231173380035, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI73915090, Length=571, Percent_Identity=30.8231173380035, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI73915096, Length=571, Percent_Identity=30.8231173380035, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI73915094, Length=571, Percent_Identity=30.8231173380035, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI113429324, Length=571, Percent_Identity=30.122591943958, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI113429326, Length=575, Percent_Identity=29.3913043478261, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI153266885, Length=541, Percent_Identity=30.8687615526802, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI153266901, Length=542, Percent_Identity=30.6273062730627, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI153266907, Length=538, Percent_Identity=28.4386617100372, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI109148539, Length=555, Percent_Identity=28.6486486486486, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI30581157, Length=199, Percent_Identity=31.6582914572864, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI30581155, Length=199, Percent_Identity=31.6582914572864, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1789856, Length=571, Percent_Identity=36.4273204903678, Blast_Score=265, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI212646519, Length=564, Percent_Identity=29.7872340425532, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI72000294, Length=564, Percent_Identity=29.7872340425532, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193208245, Length=556, Percent_Identity=30.5755395683453, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI193208247, Length=556, Percent_Identity=30.5755395683453, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17542894, Length=641, Percent_Identity=29.7971918876755, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17506189, Length=557, Percent_Identity=28.0071813285458, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17564448, Length=461, Percent_Identity=25.3796095444685, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72001495, Length=236, Percent_Identity=27.9661016949153, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI72001497, Length=236, Percent_Identity=27.9661016949153, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323330, Length=179, Percent_Identity=31.2849162011173, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45551474, Length=579, Percent_Identity=29.706390328152, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI161077880, Length=579, Percent_Identity=29.706390328152, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24642670, Length=579, Percent_Identity=29.706390328152, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24642666, Length=579, Percent_Identity=29.706390328152, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI161077878, Length=579, Percent_Identity=29.706390328152, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI161077496, Length=493, Percent_Identity=28.8032454361055, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI18859893, Length=468, Percent_Identity=28.8461538461538, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI18859741, Length=590, Percent_Identity=26.1016949152542, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 64840; Mature: 64708

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTPARTHSAFQLLAAAFATILLVAGCASPPPFAYSVPLQPESASGYTEKPGWATSKFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEE
VAAANPLATDAGYQVLKAGGSAIDAAIAVQMVLTLVEPQSSGIGGGAFLLHYNGKAVEAF
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEC
DGRETAPAAVDEKLFLGADGKPMAFYDGVVGGRSVGVPGTVRMLEMAHKQYGKLPWAQLF
CCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
APAITLAEGGFKVSARLATQLKNDQHLKKDPVAAAYFYQANGEPLDAGFTLRNQPLANVL
HHHHEEECCCEEEHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCHHHHHH
KKIAASGSKGLLEGDVAQAIVSKVQNHPTNPGKLSLADLAGYQAKKRDPICHDYQAQARD
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCCHHHCCCC
YRICGMPPPSSGAIAVGQILGILNNTNAATLALDTGMGGIPGSTGAAPSADWLHLYTEAS
EEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHH
RLAFADRAQYLGDPDFVQPPAGSWTSLLAPAYLADRAKLIAAQPGGQSMKVAKPGSPGGM
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCC
RAAYAPMPEQPEYGTSHISIVDAYGNAIAMTTTIEDQFGARQMVNGFLLNNELTDFSYAP
CEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCHHHCHHHHHHHEEECCCCCCCCCCC
TDAAGKPVANRVQPGKRPRSSMAPTLVFEKITGQLVMSGGSSGGALIIHDIVKTLYGVLH
CCCCCCCCHHHCCCCCCCCHHCCHHHHHHHHCCEEEEECCCCCCEEHHHHHHHHHHHHHH
WGLLPQQAIDLPNFGSLNGPSLLEEKRFAPATVEALRARGAEVREMNMTSGLQAIARGQA
HCCCCHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
HGTPVWLGGADPRREGVVMGD
CCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TPTPARTHSAFQLLAAAFATILLVAGCASPPPFAYSVPLQPESASGYTEKPGWATSKFA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEE
VAAANPLATDAGYQVLKAGGSAIDAAIAVQMVLTLVEPQSSGIGGGAFLLHYNGKAVEAF
EEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEC
DGRETAPAAVDEKLFLGADGKPMAFYDGVVGGRSVGVPGTVRMLEMAHKQYGKLPWAQLF
CCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
APAITLAEGGFKVSARLATQLKNDQHLKKDPVAAAYFYQANGEPLDAGFTLRNQPLANVL
HHHHEEECCCEEEHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCEECCCHHHHHH
KKIAASGSKGLLEGDVAQAIVSKVQNHPTNPGKLSLADLAGYQAKKRDPICHDYQAQARD
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCCHHHCCCC
YRICGMPPPSSGAIAVGQILGILNNTNAATLALDTGMGGIPGSTGAAPSADWLHLYTEAS
EEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHH
RLAFADRAQYLGDPDFVQPPAGSWTSLLAPAYLADRAKLIAAQPGGQSMKVAKPGSPGGM
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCC
RAAYAPMPEQPEYGTSHISIVDAYGNAIAMTTTIEDQFGARQMVNGFLLNNELTDFSYAP
CEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCHHHCHHHHHHHEEECCCCCCCCCCC
TDAAGKPVANRVQPGKRPRSSMAPTLVFEKITGQLVMSGGSSGGALIIHDIVKTLYGVLH
CCCCCCCCHHHCCCCCCCCHHCCHHHHHHHHCCEEEEECCCCCCEEHHHHHHHHHHHHHH
WGLLPQQAIDLPNFGSLNGPSLLEEKRFAPATVEALRARGAEVREMNMTSGLQAIARGQA
HCCCCHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
HGTPVWLGGADPRREGVVMGD
CCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA