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The map label for this gene is lldD [H]

Identifier: 91788909

GI number: 91788909

Start: 3216257

End: 3217396

Strand: Direct

Name: lldD [H]

Synonym: Bpro_3049

Alternate gene names: 91788909

Gene position: 3216257-3217396 (Clockwise)

Preceding gene: 91788908

Following gene: 91788910

Centisome position: 61.85

GC content: 64.65

Gene sequence:

>1140_bases
ATGAGCGCAGTCAAAACAATCGCCGTACCTGCCGTCGAGCCCTTGCCGTCCGGTCTGGTCACACTGGCCGACCATGAGGC
TCAAGCACGCGAGCGGCTGGATGACAACGCCTGGGCATATTTCAGTGGTGGTGCCGGGGACGAATTGACCCTGCGTGCCA
ACCGCACGGCCTGGGACAACCTGACCTTGCTGCCCCGCGTACTGCGTCCGATGGCTGGTGGACACACCAAAATCGAGTTG
ATGGGGCGCACACTGGCCCACCCGCTGTTATTGGCGCCGGTGGCTTACCAGCGCATGGCCCACCCTGACGGGGAGATCGC
CACCGCCCATGCCGCGGCCTCCCAAGGCGCGGGCCTGGTGCTCAGCACGCAAGCCAGCGTGCCACTGGAAACCGTAGCCG
AAGCTTTTGGCGCCTACGCTGAACGCGGGCCGTTATGGTTTCAGCTTTACTTCCAGCACGACCGCGGCTTCACGCGTGAA
CTTGTTCAACGCGCGGAACATGCAGGTTACGAAGCGCTGGTACTTACCGTAGATGCACCAACCAGCGGTGCGCGTGACCG
TGAGCGGCGCGTCGCCTTCAAGCTGCCGGCGGGAATCTCCGCCGTCAACCTTGCGCGCCTTTCACCGCAGCCCTCGAATC
CCGGGCCTGGATACAACGCCCTGTTCGACGGCCTGCTCGCGCATGCGCCGACCTGGGCCGACGTCGAATGGCTCCAGTCC
ACGACACGGTTACCGGTGGTACTCAAAGGCGTACTGCATCCCGAAGACGCGCGCCAGGCTGCAGCGCTGCGGCTTGCGGC
CTTGATCGTCTCAAATCATGGCGGCCGCACACTGGACACCGCCCCTGCGACGGCCACCATACTGCCGCGCATTGCCGAAG
CGCTGGCCGGTGATCTGCCGCTATTGGTGGATGGCGGAATCCGCCGTGGCACCGACGTGCTCAAGGCTATCGCCCTGGGG
GCTCGTGCCGTGCTGGTCGGACGTCCGTATGTGTATGGCCTTGCCAATGCCGGAGCCTTGGGCGTAGCGCATGTGCTGCG
CCTGTTGCGCGACGAACTGGAAATCGCCATGGCCCTGTGCGGCTGCGCCACGCTGGATCAGGCGACCCCCGAGCTTTTGT
TCAAGGCCTGTTCACGGTAA

Upstream 100 bases:

>100_bases
ACATGGCCCTGATGCAGCTTCGCCAGGAGCACGGCGAGAGCCAGGCCACCGTCGCGCTCACAGGCGCCTACCACAACCTG
CTCCGCATGTGGGCCGACAC

Downstream 100 bases:

>100_bases
AAGGGGAGATGCGTTTTAGCGTGAGCAGGCCCTAGTCAAATATCCTGAAATTTCCGTGGCTATTGCTCAGATATTGCAAA
TGCGATAGATTCGCATTTAT

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSAVKTIAVPAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDNLTLLPRVLRPMAGGHTKIEL
MGRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLVLSTQASVPLETVAEAFGAYAERGPLWFQLYFQHDRGFTRE
LVQRAEHAGYEALVLTVDAPTSGARDRERRVAFKLPAGISAVNLARLSPQPSNPGPGYNALFDGLLAHAPTWADVEWLQS
TTRLPVVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLPLLVDGGIRRGTDVLKAIALG
ARAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALCGCATLDQATPELLFKACSR

Sequences:

>Translated_379_residues
MSAVKTIAVPAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDNLTLLPRVLRPMAGGHTKIEL
MGRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLVLSTQASVPLETVAEAFGAYAERGPLWFQLYFQHDRGFTRE
LVQRAEHAGYEALVLTVDAPTSGARDRERRVAFKLPAGISAVNLARLSPQPSNPGPGYNALFDGLLAHAPTWADVEWLQS
TTRLPVVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLPLLVDGGIRRGTDVLKAIALG
ARAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALCGCATLDQATPELLFKACSR
>Mature_378_residues
SAVKTIAVPAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDNLTLLPRVLRPMAGGHTKIELM
GRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLVLSTQASVPLETVAEAFGAYAERGPLWFQLYFQHDRGFTREL
VQRAEHAGYEALVLTVDAPTSGARDRERRVAFKLPAGISAVNLARLSPQPSNPGPGYNALFDGLLAHAPTWADVEWLQST
TRLPVVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLPLLVDGGIRRGTDVLKAIALGA
RAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALCGCATLDQATPELLFKACSR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=362, Percent_Identity=41.7127071823204, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI54234014, Length=355, Percent_Identity=37.7464788732394, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI7705393, Length=355, Percent_Identity=37.7464788732394, Blast_Score=245, Evalue=5e-65,
Organism=Escherichia coli, GI1790033, Length=380, Percent_Identity=36.3157894736842, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI193208036, Length=360, Percent_Identity=37.2222222222222, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI32566217, Length=280, Percent_Identity=35, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323587, Length=367, Percent_Identity=34.3324250681199, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281363140, Length=359, Percent_Identity=42.0612813370474, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI78707190, Length=359, Percent_Identity=42.0612813370474, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI78707188, Length=359, Percent_Identity=42.0612813370474, Blast_Score=260, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 40219; Mature: 40087

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVKTIAVPAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDN
CCCCCEEECCCCCCCCCCCEEECCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCC
LTLLPRVLRPMAGGHTKIELMGRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLV
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEE
LSTQASVPLETVAEAFGAYAERGPLWFQLYFQHDRGFTRELVQRAEHAGYEALVLTVDAP
EECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECC
TSGARDRERRVAFKLPAGISAVNLARLSPQPSNPGPGYNALFDGLLAHAPTWADVEWLQS
CCCCCCHHCEEEEECCCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
TTRLPVVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLP
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCCC
LLVDGGIRRGTDVLKAIALGARAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALC
EEECCCCCCHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
GCATLDQATPELLFKACSR
HHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
SAVKTIAVPAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDN
CCCCEEECCCCCCCCCCCEEECCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCC
LTLLPRVLRPMAGGHTKIELMGRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLV
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCEE
LSTQASVPLETVAEAFGAYAERGPLWFQLYFQHDRGFTRELVQRAEHAGYEALVLTVDAP
EECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECC
TSGARDRERRVAFKLPAGISAVNLARLSPQPSNPGPGYNALFDGLLAHAPTWADVEWLQS
CCCCCCHHCEEEEECCCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
TTRLPVVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLP
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHCCCC
LLVDGGIRRGTDVLKAIALGARAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALC
EEECCCCCCHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
GCATLDQATPELLFKACSR
HHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA