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The map label for this gene is rnr [H]

Identifier: 91788785

GI number: 91788785

Start: 3088102

End: 3089580

Strand: Direct

Name: rnr [H]

Synonym: Bpro_2925

Alternate gene names: 91788785

Gene position: 3088102-3089580 (Clockwise)

Preceding gene: 91788784

Following gene: 91788786

Centisome position: 59.38

GC content: 68.49

Gene sequence:

>1479_bases
ATGGACACCATCAATCTGCACCGAATCGCCGTCGAGGCGATGCACTCCCGAGGTTTGCTGCCCGCCTTTGCACCGCAAAC
CTTGCAAGAGGCCGAAGCCGCGCGCCGGACGGGCCCTGAACGCAATGGCACCATCCACGACCTGCGGCATCTGACCTGGT
TCTCGATTGACAACGACGACACGCGCGACCTTGACCAGCTGAGCGTGGCCGAGCCGCTGGCCGCTGGCAGCACGCGCCTG
CGGGTGGCCGTGGCCGATGTCGATGCCATGGTGCGACCCGGCGGTGCGGTGGATGGCCATGCGGCCGTCAACACCACCTC
GGTGTACACGGCGGCCGGCGTGTTTCCGATGCTGCCGGAGGTCCTGTCTACCGACCTCACCTCGCTGCACGAAGGCCAGG
AGCGCCTGGCGGTGGTAGTCGACATGCAGGTAGAAGCAGACGGCACGGTGTCCGAGTCAACCATCTACCGGGCGGCGGTG
CTCAATCGCGCCAAGCTCACCTACGACGCCGTCTCGGCGTGGCTTGACGATGTGGGGCCACCACCGTCGCAGACCGCCAG
CGTGCAGGGACTGGAGGATCAGGTGCGTTTGCACGACGCATTGGCCAGCCAGTTGCGGCAATGGCGCCAGACGCGCGGCG
CGCTGAATGTCAACACGGTGTCCGCCCGCCCGGTGTTCAAGGACGGGCAACTGACGGACCTGCGCCCGGACGAGAAAAAC
CGCGCCAAGGACCTGATCGCCGACCTCATGATCGCGGCCAACGGCGCAACGGCCCGCTTTCTGGTCGACATGGGCTTCCC
CTCGCTGCGCCGCTTCCTGCAGGCGCCGCGCCGCTGGGACCGCATCGTTGCGCTGGCGGCGAGCCATGGCGTGCAGCTGC
CTGCGGCGCCCGATGCGCTGGCGCTCGACCGCTTCCTGTGCGCGCGGCGCCTGGTCGATCCGGCCGGTTTCGCCGATCTG
TCGCTGGCGGTGGTGAAGATGCTGGGCTCGGGCGAGTACGCGGCTGCGCCCGCTACCTCGCCCAGTGCGGCCGGCGCGGC
GGGTACCACGGGACTGGGGCACTTCGGGCTCGCGGTGAACGACTACGCGCATTCCACCGCGCCCAACCGGCGCTTTCCCG
ACCTGGTGACGCAGCGCCTGTTGAAGGCCGCCCTCGCCGGCGAGGTGCCGCCCTATTCGGCCGAACAGCTCACCGGGATC
GCCCGGCATTGCACGCTGCAGGAAGACAACGCCAGCAAGGTCGAGCGCCAGGTGCTGAAGGCCGCGGGGGCCTGGCTGCT
GCAAGGGCGCATTGGCGAGGTGTTCGGCGCCATCGTCACCGGCGCCGCGGCCAAGGGCACCTACGTGCGCATCAGCAGCC
CCATGCTGGAAGGCCGGGTGGTGCGCGGTTTCGAAGGGCTGGATGTGGGCGACACGGTGCGCGTCAGGCTGGTGGCGGTG
GATGCAGAAAAAAGCTTCATCGATTTCGAACGCGCTTGA

Upstream 100 bases:

>100_bases
TATTTGAGTCGCCAGACGTCCGGCCTGTCCGAAATGCGTCGCTGCAAGCCCATGGTCGGGGTCAGCGGGTACATTGGTAC
GAATCACTCACTGGCACCTT

Downstream 100 bases:

>100_bases
TTGGGCGGAATGTAACGCCCGGTGAACAAGCCCTTGCAGCAGGTACGGCCGGCGCCATTTGGGCTGAACACGGCCCGCTG
GGGCCAGTCATCGAGGAGCT

Product: exoribonuclease II

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MDTINLHRIAVEAMHSRGLLPAFAPQTLQEAEAARRTGPERNGTIHDLRHLTWFSIDNDDTRDLDQLSVAEPLAAGSTRL
RVAVADVDAMVRPGGAVDGHAAVNTTSVYTAAGVFPMLPEVLSTDLTSLHEGQERLAVVVDMQVEADGTVSESTIYRAAV
LNRAKLTYDAVSAWLDDVGPPPSQTASVQGLEDQVRLHDALASQLRQWRQTRGALNVNTVSARPVFKDGQLTDLRPDEKN
RAKDLIADLMIAANGATARFLVDMGFPSLRRFLQAPRRWDRIVALAASHGVQLPAAPDALALDRFLCARRLVDPAGFADL
SLAVVKMLGSGEYAAAPATSPSAAGAAGTTGLGHFGLAVNDYAHSTAPNRRFPDLVTQRLLKAALAGEVPPYSAEQLTGI
ARHCTLQEDNASKVERQVLKAAGAWLLQGRIGEVFGAIVTGAAAKGTYVRISSPMLEGRVVRGFEGLDVGDTVRVRLVAV
DAEKSFIDFERA

Sequences:

>Translated_492_residues
MDTINLHRIAVEAMHSRGLLPAFAPQTLQEAEAARRTGPERNGTIHDLRHLTWFSIDNDDTRDLDQLSVAEPLAAGSTRL
RVAVADVDAMVRPGGAVDGHAAVNTTSVYTAAGVFPMLPEVLSTDLTSLHEGQERLAVVVDMQVEADGTVSESTIYRAAV
LNRAKLTYDAVSAWLDDVGPPPSQTASVQGLEDQVRLHDALASQLRQWRQTRGALNVNTVSARPVFKDGQLTDLRPDEKN
RAKDLIADLMIAANGATARFLVDMGFPSLRRFLQAPRRWDRIVALAASHGVQLPAAPDALALDRFLCARRLVDPAGFADL
SLAVVKMLGSGEYAAAPATSPSAAGAAGTTGLGHFGLAVNDYAHSTAPNRRFPDLVTQRLLKAALAGEVPPYSAEQLTGI
ARHCTLQEDNASKVERQVLKAAGAWLLQGRIGEVFGAIVTGAAAKGTYVRISSPMLEGRVVRGFEGLDVGDTVRVRLVAV
DAEKSFIDFERA
>Mature_492_residues
MDTINLHRIAVEAMHSRGLLPAFAPQTLQEAEAARRTGPERNGTIHDLRHLTWFSIDNDDTRDLDQLSVAEPLAAGSTRL
RVAVADVDAMVRPGGAVDGHAAVNTTSVYTAAGVFPMLPEVLSTDLTSLHEGQERLAVVVDMQVEADGTVSESTIYRAAV
LNRAKLTYDAVSAWLDDVGPPPSQTASVQGLEDQVRLHDALASQLRQWRQTRGALNVNTVSARPVFKDGQLTDLRPDEKN
RAKDLIADLMIAANGATARFLVDMGFPSLRRFLQAPRRWDRIVALAASHGVQLPAAPDALALDRFLCARRLVDPAGFADL
SLAVVKMLGSGEYAAAPATSPSAAGAAGTTGLGHFGLAVNDYAHSTAPNRRFPDLVTQRLLKAALAGEVPPYSAEQLTGI
ARHCTLQEDNASKVERQVLKAAGAWLLQGRIGEVFGAIVTGAAAKGTYVRISSPMLEGRVVRGFEGLDVGDTVRVRLVAV
DAEKSFIDFERA

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=392, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI19115966, Length=412, Percent_Identity=26.2135922330097, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI219521928, Length=412, Percent_Identity=26.2135922330097, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI190014623, Length=352, Percent_Identity=25.5681818181818, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI190014625, Length=352, Percent_Identity=25.5681818181818, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI87082383, Length=511, Percent_Identity=29.3542074363992, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787542, Length=387, Percent_Identity=29.1989664082687, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI212645896, Length=424, Percent_Identity=25, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17553506, Length=379, Percent_Identity=23.7467018469657, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324552, Length=356, Percent_Identity=27.8089887640449, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24654592, Length=370, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19922976, Length=370, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24654597, Length=370, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24649634, Length=382, Percent_Identity=24.6073298429319, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 52667; Mature: 52667

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00935 GLYOXALASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTINLHRIAVEAMHSRGLLPAFAPQTLQEAEAARRTGPERNGTIHDLRHLTWFSIDNDD
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCC
TRDLDQLSVAEPLAAGSTRLRVAVADVDAMVRPGGAVDGHAAVNTTSVYTAAGVFPMLPE
CCCHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHH
VLSTDLTSLHEGQERLAVVVDMQVEADGTVSESTIYRAAVLNRAKLTYDAVSAWLDDVGP
HHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPSQTASVQGLEDQVRLHDALASQLRQWRQTRGALNVNTVSARPVFKDGQLTDLRPDEKN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHH
RAKDLIADLMIAANGATARFLVDMGFPSLRRFLQAPRRWDRIVALAASHGVQLPAAPDAL
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCCHH
ALDRFLCARRLVDPAGFADLSLAVVKMLGSGEYAAAPATSPSAAGAAGTTGLGHFGLAVN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
DYAHSTAPNRRFPDLVTQRLLKAALAGEVPPYSAEQLTGIARHCTLQEDNASKVERQVLK
CHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AAGAWLLQGRIGEVFGAIVTGAAAKGTYVRISSPMLEGRVVRGFEGLDVGDTVRVRLVAV
HHCHHHHHCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEE
DAEKSFIDFERA
ECCCCCCCCCCC
>Mature Secondary Structure
MDTINLHRIAVEAMHSRGLLPAFAPQTLQEAEAARRTGPERNGTIHDLRHLTWFSIDNDD
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCC
TRDLDQLSVAEPLAAGSTRLRVAVADVDAMVRPGGAVDGHAAVNTTSVYTAAGVFPMLPE
CCCHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHH
VLSTDLTSLHEGQERLAVVVDMQVEADGTVSESTIYRAAVLNRAKLTYDAVSAWLDDVGP
HHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPSQTASVQGLEDQVRLHDALASQLRQWRQTRGALNVNTVSARPVFKDGQLTDLRPDEKN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHH
RAKDLIADLMIAANGATARFLVDMGFPSLRRFLQAPRRWDRIVALAASHGVQLPAAPDAL
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCCHH
ALDRFLCARRLVDPAGFADLSLAVVKMLGSGEYAAAPATSPSAAGAAGTTGLGHFGLAVN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
DYAHSTAPNRRFPDLVTQRLLKAALAGEVPPYSAEQLTGIARHCTLQEDNASKVERQVLK
CHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AAGAWLLQGRIGEVFGAIVTGAAAKGTYVRISSPMLEGRVVRGFEGLDVGDTVRVRLVAV
HHCHHHHHCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCEEEEEEEE
DAEKSFIDFERA
ECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]