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The map label for this gene is dppA [H]

Identifier: 91788678

GI number: 91788678

Start: 2959984

End: 2961621

Strand: Direct

Name: dppA [H]

Synonym: Bpro_2816

Alternate gene names: 91788678

Gene position: 2959984-2961621 (Clockwise)

Preceding gene: 91788677

Following gene: 91788681

Centisome position: 56.92

GC content: 57.81

Gene sequence:

>1638_bases
ATGATTCAGACCAAACCAAGTGCAAGCCGGCTACGCCCGGTCCAGCGCGCATTGCTGTGCGCGATCGCCCTGCCAGCATT
GCTGGCGCTCACGCCGGCGTCCGCCAAGACGCTGGTGTTCTGCTCTGAAGGCAGTCCTGAAAACTTCTACCCCGGTATCA
ACACCACGGGTACCTCGTTTGATGCCAACGAACCCATCTACAACCGTATCGTGGAGTTTGAGCGTGGCGGCACCAAGGTA
ATGCCGGGACTGGCCGAGAAATGGGATATCTCTGCCGATGGCAAGGAATACACCTTCCATCTGCGCAAAGGCGTGAAATG
GCATAACACCAGCAAGAGCTTCAAGCCCACCCGCGACTTCAATGCCGACGACGTACTGTTCATGTTCGAGCGTCAGTGGA
AAGAAGACAACCCATTCTTCAAGGTCACCAGTCCCAACCACTCCTACTTCAGCGACATGGGCATGCCCAAGCTGCTGAAA
TCGGTGCAAAAAGTCAACGACTACACCGTCAAGATCACGCTCGACAAACCTGAAGCACCGTTCCTGTCCAACCTGGCCAT
GCCTTATGCAGCGGTGCAGTCCAAGGAATATGCCGACGCCATGCTCAAGGCCGGCACCCCCGAAAAAATTGACCAGGATC
CTGTTGGAACCGGCCCCTTCTACCTGGTGCAATACCAGAAAGACGCGATCATCCGTTACAAGGCCTTCCCTCAGCATTTT
GCGGGCAAAGCCAAGATCGACGACCTCGTCTACGCGATCACGCCGGACGCCTCGGTGCGATGGGCGAAGCTGCAAAAAGG
CGAGTGCCATGTGATGCCCTACCCGGCTCCGGCTGACCTCGAAGCCATCCGCAAGGACCCGAATATCCAGGTCATCGAGC
AACCCGGTTTGAACGTAGGGTATCTGGCTTACAACACCACGAAAAAGCCGTTTGATGACGTGCGCGTGCGCAAGGCCATC
AACATGTCCATCAACAAGAAAGCCATTGTTGACGGCGTGTACCTCGGCACCGGCATTCCCGCGAAAAACCCGATTCCACC
GTCGATGGCTGCCTACAACGACAGCATCAAGGACGACGCCTACAACCCTGAAGCCGCCAAAAAACTCCTGGCAGAAGCAG
GCTACCCGAACGGCTTCACCACCGATTTGTGGGCCATGCCGGTGCAGCGCCCCTACAACCCCAACGCCAAACGCATTGCC
GAGCTGATGCAGGCGGACCTGGTCAAGGTGGGCGTCACGGCCGAGATCAAGAGCTTTGAGTGGGGCGAGTACCGCAAGCG
CCTGCAGGCCGGCGAGCACCAGATGGGCATGCTGGGCTGGACCGGCGACAACGGCGATCCGGACAACTTCATGTACACCC
TGCTTGGTTGCGCTTCAGCCCAGTCCGCCAGTGGTTCCAACATCGCCAAGTTCTGCTACCAGCCTTATGAAGATCTGGTC
CTGAAAGCCAAGACCGTCACCAACCCGGCCGAGCGCACCAAGCTGTACCAGCAGGCCCAGGTGATCTTCAAGGAGCAGGC
GCCCTGGTTCACGATTGCCCATGCGGTGCAGCTCAAGCCGGTACGCAAGAGCGTGATCGACTTCAAGAACAGCCCATTCG
GCCGACACAACTTCTACGGCGTCGACATCAAGGAATAA

Upstream 100 bases:

>100_bases
GCCACGTTTTTCAAAGACCGGGGAGCGCAGAACACAATTCGCGCAAACTGGCCGCCAGCCCGCTGCATCGCAGCATTAAC
CCCCAAAGGGAGTCCGTCAA

Downstream 100 bases:

>100_bases
GCCCTCCAAGGCCAATACGGTTCAGTTAAGCCCTTGCCCCTGGTTTGTCATCCCGGACTTGACCCGGATCCATGGATTGC
GGGTCAGGCCCGCAATGACA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MIQTKPSASRLRPVQRALLCAIALPALLALTPASAKTLVFCSEGSPENFYPGINTTGTSFDANEPIYNRIVEFERGGTKV
MPGLAEKWDISADGKEYTFHLRKGVKWHNTSKSFKPTRDFNADDVLFMFERQWKEDNPFFKVTSPNHSYFSDMGMPKLLK
SVQKVNDYTVKITLDKPEAPFLSNLAMPYAAVQSKEYADAMLKAGTPEKIDQDPVGTGPFYLVQYQKDAIIRYKAFPQHF
AGKAKIDDLVYAITPDASVRWAKLQKGECHVMPYPAPADLEAIRKDPNIQVIEQPGLNVGYLAYNTTKKPFDDVRVRKAI
NMSINKKAIVDGVYLGTGIPAKNPIPPSMAAYNDSIKDDAYNPEAAKKLLAEAGYPNGFTTDLWAMPVQRPYNPNAKRIA
ELMQADLVKVGVTAEIKSFEWGEYRKRLQAGEHQMGMLGWTGDNGDPDNFMYTLLGCASAQSASGSNIAKFCYQPYEDLV
LKAKTVTNPAERTKLYQQAQVIFKEQAPWFTIAHAVQLKPVRKSVIDFKNSPFGRHNFYGVDIKE

Sequences:

>Translated_545_residues
MIQTKPSASRLRPVQRALLCAIALPALLALTPASAKTLVFCSEGSPENFYPGINTTGTSFDANEPIYNRIVEFERGGTKV
MPGLAEKWDISADGKEYTFHLRKGVKWHNTSKSFKPTRDFNADDVLFMFERQWKEDNPFFKVTSPNHSYFSDMGMPKLLK
SVQKVNDYTVKITLDKPEAPFLSNLAMPYAAVQSKEYADAMLKAGTPEKIDQDPVGTGPFYLVQYQKDAIIRYKAFPQHF
AGKAKIDDLVYAITPDASVRWAKLQKGECHVMPYPAPADLEAIRKDPNIQVIEQPGLNVGYLAYNTTKKPFDDVRVRKAI
NMSINKKAIVDGVYLGTGIPAKNPIPPSMAAYNDSIKDDAYNPEAAKKLLAEAGYPNGFTTDLWAMPVQRPYNPNAKRIA
ELMQADLVKVGVTAEIKSFEWGEYRKRLQAGEHQMGMLGWTGDNGDPDNFMYTLLGCASAQSASGSNIAKFCYQPYEDLV
LKAKTVTNPAERTKLYQQAQVIFKEQAPWFTIAHAVQLKPVRKSVIDFKNSPFGRHNFYGVDIKE
>Mature_545_residues
MIQTKPSASRLRPVQRALLCAIALPALLALTPASAKTLVFCSEGSPENFYPGINTTGTSFDANEPIYNRIVEFERGGTKV
MPGLAEKWDISADGKEYTFHLRKGVKWHNTSKSFKPTRDFNADDVLFMFERQWKEDNPFFKVTSPNHSYFSDMGMPKLLK
SVQKVNDYTVKITLDKPEAPFLSNLAMPYAAVQSKEYADAMLKAGTPEKIDQDPVGTGPFYLVQYQKDAIIRYKAFPQHF
AGKAKIDDLVYAITPDASVRWAKLQKGECHVMPYPAPADLEAIRKDPNIQVIEQPGLNVGYLAYNTTKKPFDDVRVRKAI
NMSINKKAIVDGVYLGTGIPAKNPIPPSMAAYNDSIKDDAYNPEAAKKLLAEAGYPNGFTTDLWAMPVQRPYNPNAKRIA
ELMQADLVKVGVTAEIKSFEWGEYRKRLQAGEHQMGMLGWTGDNGDPDNFMYTLLGCASAQSASGSNIAKFCYQPYEDLV
LKAKTVTNPAERTKLYQQAQVIFKEQAPWFTIAHAVQLKPVRKSVIDFKNSPFGRHNFYGVDIKE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=528, Percent_Identity=57.3863636363636, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1787551, Length=505, Percent_Identity=34.2574257425743, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1787052, Length=553, Percent_Identity=28.9330922242315, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787762, Length=536, Percent_Identity=25.5597014925373, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789397, Length=474, Percent_Identity=25.9493670886076, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787495, Length=552, Percent_Identity=25.7246376811594, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789887, Length=472, Percent_Identity=23.9406779661017, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081878, Length=457, Percent_Identity=26.0393873085339, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60963; Mature: 60963

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTKPSASRLRPVQRALLCAIALPALLALTPASAKTLVFCSEGSPENFYPGINTTGTSF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
DANEPIYNRIVEFERGGTKVMPGLAEKWDISADGKEYTFHLRKGVKWHNTSKSFKPTRDF
CCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCC
NADDVLFMFERQWKEDNPFFKVTSPNHSYFSDMGMPKLLKSVQKVNDYTVKITLDKPEAP
CCCCEEEEEEHHCCCCCCEEEEECCCCHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCC
FLSNLAMPYAAVQSKEYADAMLKAGTPEKIDQDPVGTGPFYLVQYQKDAIIRYKAFPQHF
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHH
AGKAKIDDLVYAITPDASVRWAKLQKGECHVMPYPAPADLEAIRKDPNIQVIEQPGLNVG
CCCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCCHHHHHCCCCEEEEECCCCEEE
YLAYNTTKKPFDDVRVRKAINMSINKKAIVDGVYLGTGIPAKNPIPPSMAAYNDSIKDDA
EEEECCCCCCHHHHHHHHHHCCCCCCHHEECEEEECCCCCCCCCCCCCHHHCCCCCCCCC
YNPEAAKKLLAEAGYPNGFTTDLWAMPVQRPYNPNAKRIAELMQADLVKVGVTAEIKSFE
CCHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCHHHHHHHHHHHHEEECCEEEECCCC
WGEYRKRLQAGEHQMGMLGWTGDNGDPDNFMYTLLGCASAQSASGSNIAKFCYQPYEDLV
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHH
LKAKTVTNPAERTKLYQQAQVIFKEQAPWFTIAHAVQLKPVRKSVIDFKNSPFGRHNFYG
EEHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHEEHHHHHHHHHHCCCCCCCCCCEEE
VDIKE
EEECC
>Mature Secondary Structure
MIQTKPSASRLRPVQRALLCAIALPALLALTPASAKTLVFCSEGSPENFYPGINTTGTSF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
DANEPIYNRIVEFERGGTKVMPGLAEKWDISADGKEYTFHLRKGVKWHNTSKSFKPTRDF
CCCCHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCEECCCCCCCCCCCCC
NADDVLFMFERQWKEDNPFFKVTSPNHSYFSDMGMPKLLKSVQKVNDYTVKITLDKPEAP
CCCCEEEEEEHHCCCCCCEEEEECCCCHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCC
FLSNLAMPYAAVQSKEYADAMLKAGTPEKIDQDPVGTGPFYLVQYQKDAIIRYKAFPQHF
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHH
AGKAKIDDLVYAITPDASVRWAKLQKGECHVMPYPAPADLEAIRKDPNIQVIEQPGLNVG
CCCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCCHHHHHCCCCEEEEECCCCEEE
YLAYNTTKKPFDDVRVRKAINMSINKKAIVDGVYLGTGIPAKNPIPPSMAAYNDSIKDDA
EEEECCCCCCHHHHHHHHHHCCCCCCHHEECEEEECCCCCCCCCCCCCHHHCCCCCCCCC
YNPEAAKKLLAEAGYPNGFTTDLWAMPVQRPYNPNAKRIAELMQADLVKVGVTAEIKSFE
CCHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCHHHHHHHHHHHHEEECCEEEECCCC
WGEYRKRLQAGEHQMGMLGWTGDNGDPDNFMYTLLGCASAQSASGSNIAKFCYQPYEDLV
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHH
LKAKTVTNPAERTKLYQQAQVIFKEQAPWFTIAHAVQLKPVRKSVIDFKNSPFGRHNFYG
EEHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHEEHHHHHHHHHHCCCCCCCCCCEEE
VDIKE
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]