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The map label for this gene is carA [H]

Identifier: 91788541

GI number: 91788541

Start: 2820195

End: 2821400

Strand: Reverse

Name: carA [H]

Synonym: Bpro_2679

Alternate gene names: 91788541

Gene position: 2821400-2820195 (Counterclockwise)

Preceding gene: 91788542

Following gene: 91788540

Centisome position: 54.25

GC content: 60.2

Gene sequence:

>1206_bases
GTGCTTTTGTCTCTACAGGGAATATCAGGACAACCCCCTCACGCCATCCTGGCGCTCGCAGACGGCACGGTCTTTATCGG
CAATTCGATTGGAGCGCCAGGCTCCACGATCGGCGAGGTGGTGTTCAACACCGCCATGACCGGCTACCAGGAAATCCTCA
CGGACCCGAGCTACTGCCAGCAGATCGTTACCCTTACCTATCCGCATATCGGCAACTATGGCATCAACGCCGAAGACATC
GAGGCCGACAAAGTCCATGCCGCCGGCCTGATCATCAAGGACCTGCCGCTGCTGGCCTCCAATTTCCGCATGTCCATGAC
CTTGTCCGAGTATCTGGTCAAGGAGGGCACGGTGGCCATCGCCGGCATCGACACCCGCCAACTCACACGCCTGCTTCGCA
CCAATGGTGCACAAAACGGGTGCATTCTGGCGCTGCCTGAAGGTGAAGAGGTCAGCCAGCCTGCCATCGAAAAGGCCGTG
GCTGCCGCGCGCGGCGCGCCCAGCATGGCTGGCCTGGACCTGGCTAAGGTCGTGTCCGCCAAGCAGACCTACGAATGGAC
GCAAACCGAGTGGAAGCTCATGAACCTGGAAGGCAAGCCGGGCTATGGTGTGCAGATCACCCCAAAATTCCACGTGGTGG
CTTATGACTTTGGCGTCAAGAAAAACATCCTGCGCATGATGGCCGAGCGCGGTGCGCGTATCACCGTGGTGCCGGCGCAA
ACTCCGGCCGCCGATGTGCTCAAGCTCAAGCCTGACGGCATTTTCCTCGCCAACGGCCCGGGTGATCCGGAGCCGTGCGA
CTACGCCATTGCTGCCGTGCGCGAATTGATCGAGACCGGCATTCCCACCTTCGGTATCTGCCTGGGCCACCAGATCATGG
CACTGGCCAGCGGAGCCAAAACCTTCAAGATGAAGTTTGGTCACCACGGCGCCAACCATCCGGTCAAGGACCTCGACAAC
GGCCGTGTCAGCATCACCAGCCAGAACCACGGTTTTGCAGTGGACGAGAAAAGCCTGCCCGCCAACCTGCGGCCCACGCA
CATCAGCCTGTTTGATGGCACGCTGCAGGGCCTGGCACGCACCGACAAGCCCGCGTTCTGCTTTCAGGGACACCCTGAAG
CGTCACCCGGCCCGCATGACATTTCGTATTTGTTTGACCGTTTCACCGCGCTGATGGAACAGGCAGGGGAGAAGAAGAAT
GCCTAA

Upstream 100 bases:

>100_bases
CGCATACCAAGCCAACACCCTCACAAAAGCAGCCCGCAAGAGTCTTAAGAGACGTTTCTTGTGCATGCTTGGGCGAACCG
TAACCAACCCGGAGAACCCA

Downstream 100 bases:

>100_bases
GCGCACAGACATCAAGAGCGTCCTCATCATCGGCGCCGGCCCGATCATCATCGGCCAGGCCTGCGAGTTCGATTACTCCG
GCGTGCAGGCCTGCAAGGCC

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLLSLQGISGQPPHAILALADGTVFIGNSIGAPGSTIGEVVFNTAMTGYQEILTDPSYCQQIVTLTYPHIGNYGINAEDI
EADKVHAAGLIIKDLPLLASNFRMSMTLSEYLVKEGTVAIAGIDTRQLTRLLRTNGAQNGCILALPEGEEVSQPAIEKAV
AAARGAPSMAGLDLAKVVSAKQTYEWTQTEWKLMNLEGKPGYGVQITPKFHVVAYDFGVKKNILRMMAERGARITVVPAQ
TPAADVLKLKPDGIFLANGPGDPEPCDYAIAAVRELIETGIPTFGICLGHQIMALASGAKTFKMKFGHHGANHPVKDLDN
GRVSITSQNHGFAVDEKSLPANLRPTHISLFDGTLQGLARTDKPAFCFQGHPEASPGPHDISYLFDRFTALMEQAGEKKN
A

Sequences:

>Translated_401_residues
MLLSLQGISGQPPHAILALADGTVFIGNSIGAPGSTIGEVVFNTAMTGYQEILTDPSYCQQIVTLTYPHIGNYGINAEDI
EADKVHAAGLIIKDLPLLASNFRMSMTLSEYLVKEGTVAIAGIDTRQLTRLLRTNGAQNGCILALPEGEEVSQPAIEKAV
AAARGAPSMAGLDLAKVVSAKQTYEWTQTEWKLMNLEGKPGYGVQITPKFHVVAYDFGVKKNILRMMAERGARITVVPAQ
TPAADVLKLKPDGIFLANGPGDPEPCDYAIAAVRELIETGIPTFGICLGHQIMALASGAKTFKMKFGHHGANHPVKDLDN
GRVSITSQNHGFAVDEKSLPANLRPTHISLFDGTLQGLARTDKPAFCFQGHPEASPGPHDISYLFDRFTALMEQAGEKKN
A
>Mature_401_residues
MLLSLQGISGQPPHAILALADGTVFIGNSIGAPGSTIGEVVFNTAMTGYQEILTDPSYCQQIVTLTYPHIGNYGINAEDI
EADKVHAAGLIIKDLPLLASNFRMSMTLSEYLVKEGTVAIAGIDTRQLTRLLRTNGAQNGCILALPEGEEVSQPAIEKAV
AAARGAPSMAGLDLAKVVSAKQTYEWTQTEWKLMNLEGKPGYGVQITPKFHVVAYDFGVKKNILRMMAERGARITVVPAQ
TPAADVLKLKPDGIFLANGPGDPEPCDYAIAAVRELIETGIPTFGICLGHQIMALASGAKTFKMKFGHHGANHPVKDLDN
GRVSITSQNHGFAVDEKSLPANLRPTHISLFDGTLQGLARTDKPAFCFQGHPEASPGPHDISYLFDRFTALMEQAGEKKN
A

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=397, Percent_Identity=37.7833753148615, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI21361331, Length=404, Percent_Identity=34.6534653465347, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI169790915, Length=404, Percent_Identity=34.6534653465347, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1786215, Length=380, Percent_Identity=65, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI193204318, Length=395, Percent_Identity=37.9746835443038, Blast_Score=251, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6324878, Length=396, Percent_Identity=37.8787878787879, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6322331, Length=395, Percent_Identity=36.4556962025316, Blast_Score=236, Evalue=6e-63,
Organism=Drosophila melanogaster, GI45555749, Length=398, Percent_Identity=38.4422110552764, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24642586, Length=398, Percent_Identity=38.4422110552764, Blast_Score=232, Evalue=4e-61,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 42929; Mature: 42929

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSLQGISGQPPHAILALADGTVFIGNSIGAPGSTIGEVVFNTAMTGYQEILTDPSYCQ
CEEEECCCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QIVTLTYPHIGNYGINAEDIEADKVHAAGLIIKDLPLLASNFRMSMTLSEYLVKEGTVAI
HHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEHHCHHHHCCCEEEEEHHHHHHCCCCEEE
AGIDTRQLTRLLRTNGAQNGCILALPEGEEVSQPAIEKAVAAARGAPSMAGLDLAKVVSA
EECCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTYEWTQTEWKLMNLEGKPGYGVQITPKFHVVAYDFGVKKNILRMMAERGARITVVPAQ
HHCCCCCCCEEEEEEECCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECC
TPAADVLKLKPDGIFLANGPGDPEPCDYAIAAVRELIETGIPTFGICLGHQIMALASGAK
CCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
TFKMKFGHHGANHPVKDLDNGRVSITSQNHGFAVDEKSLPANLRPTHISLFDGTLQGLAR
EEEEEECCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHC
TDKPAFCFQGHPEASPGPHDISYLFDRFTALMEQAGEKKNA
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLSLQGISGQPPHAILALADGTVFIGNSIGAPGSTIGEVVFNTAMTGYQEILTDPSYCQ
CEEEECCCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QIVTLTYPHIGNYGINAEDIEADKVHAAGLIIKDLPLLASNFRMSMTLSEYLVKEGTVAI
HHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEHHCHHHHCCCEEEEEHHHHHHCCCCEEE
AGIDTRQLTRLLRTNGAQNGCILALPEGEEVSQPAIEKAVAAARGAPSMAGLDLAKVVSA
EECCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KQTYEWTQTEWKLMNLEGKPGYGVQITPKFHVVAYDFGVKKNILRMMAERGARITVVPAQ
HHCCCCCCCEEEEEEECCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECC
TPAADVLKLKPDGIFLANGPGDPEPCDYAIAAVRELIETGIPTFGICLGHQIMALASGAK
CCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
TFKMKFGHHGANHPVKDLDNGRVSITSQNHGFAVDEKSLPANLRPTHISLFDGTLQGLAR
EEEEEECCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEHHHHHHHHC
TDKPAFCFQGHPEASPGPHDISYLFDRFTALMEQAGEKKNA
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11343129 [H]