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The map label for this gene is engA

Identifier: 91788466

GI number: 91788466

Start: 2733911

End: 2735254

Strand: Reverse

Name: engA

Synonym: Bpro_2604

Alternate gene names: 91788466

Gene position: 2735254-2733911 (Counterclockwise)

Preceding gene: 91788467

Following gene: 91788465

Centisome position: 52.6

GC content: 59.45

Gene sequence:

>1344_bases
ATGAAACCTGTCATTGCGTTAGTCGGCCGCCCGAATGTGGGCAAGTCGACGATTTTCAACCGGCTGACCAAGACGCGGGA
TGCGATCGTGGCCGATTTCGCCGGGCTGACGCGTGACCGTCATTACGGCAATGGCAAGTTGGGCTCCCACGAGTACATCG
TCATTGACACCGGCGGGTTTGAGCCCGATGCCGCGTCCGGCATATACAAGGAAATGGCCAAGCAGACCCGTCAGGCCGTT
GCTGAAGCCGATGTGGTGATTTTCGTGGTCGACGCGCGTGCCGGCATCAGCGCGCAGGACCACGATATCGCCAACTTCCT
GCGCAAGCTGGGCAAGCCGACGGTGCTGACCGCCAACAAGGCGGAGGGCATGACGGAAGGCGTCCAGTTCTCCGAATTTT
TTGAATTGGGCCTGGGCGAAGTGCTGCCCGTTTCGGCATCCCATGGCCAGGGCATGCGTTCCCTGGTCGATCTTGCCTTG
GCGCCGCTCCATCTCGCCGATCCTGATGAAGAAGCCGAGCCGCAAGACCCGTCCGTCATCCGGCTCGCTGTGGCGGGCCG
TCCCAATGTGGGGAAATCCACGCTGATCAATACATGGCTGGGGGAAGAGCGCCTGGTGTCCTTCGACCTTCCTGGCACCA
CCCGGGATGCCATTTCCGTGCCCTTTGAGCGTGCCGGTCAGAAGTTTGAATTGATTGACACCGCCGGTCTGCGCCGCAAA
GGCAAGGTTTTTGAAGCCATCGAGAAGTTTTCCGTCGTCAAGACGCTTCAGGCGATTGAAGGTGCGAACGTCGTGCTGTT
GCTGCTCGACGCCACGCAGGGCGTGACCGACCAGGATGCACATATTGCCGGGTATATCCTTGAAAGTGGTCGTGCGGTGG
TGCTGGCCATCAACAAATGGGATGCGGTGGATGCCTACCAGCGGGAGACGCTGGAGCGGTCGATCGAGACCCGCCTTGCT
TTCCTGAAATTTGCATCCATCCACAAGATTTCGGCGATCAAGCGCCAGGGATTGGCTCCCGTCTGGAAATCAATTGTGCA
GGCCCACGCTTCGGCCAACCGCAAAATGTCCACCCCCGTGCTCACACGCCTGCTGCTTGAGGCCGTCCAGTTCCAGCAGC
CGCAGCGTTCGGGTATGTTCCGCCCCAAGATGCGCTATGCGCACCAGGGCGGCATGAATCCGCCCATCATCATCATTCAT
GGCAATTCGCTGGAGCATGTCACCGAAGCCTACAAACGCTATCTGGAAGGGCGGTTCCGCAAGGAGTTCGATCTGGTCGG
CACGCCTATGCGCATCCAGATGAAAAGCTCGCACAACCCCTTCACGGACAAGGATTCGGCCTAA

Upstream 100 bases:

>100_bases
CGGCAACACGCTGATCGCCGTGACCCACAACGGTGGGGTTTACGGTTTCAAGCCTGAGTAAACGAAATACACGAAATACA
ACCTTTCCAGAAGCTGATCG

Downstream 100 bases:

>100_bases
AACTACAGGCTGGACGTACCGGCTGTGGTAAGGTCAAGTTCTATTAACTTTTGAACACGGAAAATATCGTGAGCAATAAC
AAAGGTCAGCTGCTGCAGGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGFEPDAASGIYKEMAKQTRQAV
AEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANKAEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLAL
APLHLADPDEEAEPQDPSVIRLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKWDAVDAYQRETLERSIETRLA
FLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPVLTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIH
GNSLEHVTEAYKRYLEGRFRKEFDLVGTPMRIQMKSSHNPFTDKDSA

Sequences:

>Translated_447_residues
MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGFEPDAASGIYKEMAKQTRQAV
AEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANKAEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLAL
APLHLADPDEEAEPQDPSVIRLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKWDAVDAYQRETLERSIETRLA
FLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPVLTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIH
GNSLEHVTEAYKRYLEGRFRKEFDLVGTPMRIQMKSSHNPFTDKDSA
>Mature_447_residues
MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGFEPDAASGIYKEMAKQTRQAV
AEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANKAEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLAL
APLHLADPDEEAEPQDPSVIRLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKWDAVDAYQRETLERSIETRLA
FLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPVLTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIH
GNSLEHVTEAYKRYLEGRFRKEFDLVGTPMRIQMKSSHNPFTDKDSA

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=48.7179487179487, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=31.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=29.8611111111111, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_POLSJ (Q12AC2)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549418.1
- ProteinModelPortal:   Q12AC2
- STRING:   Q12AC2
- GeneID:   4014753
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2604
- NMPDR:   fig|296591.1.peg.320
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q12AC2
- ProtClustDB:   PRK00093
- BioCyc:   PSP296591:BPRO_2604-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49145; Mature: 49145

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
EPDAASGIYKEMAKQTRQAVAEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANK
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCC
AEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLALAPLHLADPDEEAEPQDPSVI
CCCCCCCCHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
RLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRK
EEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHEECCHHHCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKW
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCC
DAVDAYQRETLERSIETRLAFLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
LTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIHGNSLEHVTEAYKRYLEGRFR
HHHHHHHHHHHCCHHHCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KEFDLVGTPMRIQMKSSHNPFTDKDSA
HHHHHCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
EPDAASGIYKEMAKQTRQAVAEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANK
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCC
AEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLALAPLHLADPDEEAEPQDPSVI
CCCCCCCCHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
RLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRK
EEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHEECCHHHCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKW
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCC
DAVDAYQRETLERSIETRLAFLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
LTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIHGNSLEHVTEAYKRYLEGRFR
HHHHHHHHHHHCCHHHCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KEFDLVGTPMRIQMKSSHNPFTDKDSA
HHHHHCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA