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The map label for this gene is hflK [H]

Identifier: 91788463

GI number: 91788463

Start: 2730930

End: 2732354

Strand: Reverse

Name: hflK [H]

Synonym: Bpro_2601

Alternate gene names: 91788463

Gene position: 2732354-2730930 (Counterclockwise)

Preceding gene: 91788464

Following gene: 91788462

Centisome position: 52.54

GC content: 61.47

Gene sequence:

>1425_bases
ATGAACCTGAATCCCGTGCTGCAGACGTTGACGACCTTGCCAGGTCGGCTGAAACAACGCGCCCAAGGCATGTTCAATCT
CAACGATCCACGTTGGGGCCGCGACGATGACAAGCCCTCATCCGATGAGACCAAGCCAGACATGCCTCGTGACGACAAGC
AGCCTTCCAGGCCAGTTCGACCACAAGGCCAGGGGCCCAATCAGGGGCCACCTGACCTGGACGAACTCTGGCGCGATTTC
AATCGCAAGCTCGGCGGCCTCTTTGGCGGCGCAAAAAGCGCCGGCAAGCGGGGTGGCTTTGGGGGCGGTAACAACGGGGG
TGACGGCGGTAATGGCGGTGGTTTTCAGCCCGACATGAAAAGTGCGGGTATCGGCGCGGGCCTGATCGCCGCAGTGGCCG
TCCTGATCTGGCTGGGCACCGGGTTTTTCATTGTGCAAGAGGGCCAGCAGGCCGTCATTACTCAGTTCGGCAAATACCAC
TCGACCGTGGGCGCGGGTTTCAACTGGCGCCTGCCGTACCCTGTGCAGCGCCATGAAATGGTCGTGGTCACCCAGATAAG
GTCGGTTGATGTGGGGCGCGACACCATCATCAAGGCAACAGGACTTCGCGATTCGGCCATGCTGACTGAAGACGAGAACA
TTGTCGAAATCAAATTCGCGGTCCAGTACCGTTTGAGTGACGCGCGTGCCTACCTGTTTGAAAGCAAGGACCCGGCCAGC
GCCGTGGTGCAGGCTGCCGAAACGGCCGTGCGTGAAGTGGTGGGAAAAATGAAGATGGATTTGGCGCTTGCAGACGAGCG
CGACCAGATCGGCCCCCGCGTGCGGGCCCTGATGCAGATCATTCTGGACCGCTACAAGGTGGGTGTTGAAGTCGTGGGCA
TCAATCTTCAGCAAAGCGGTGTGCGTCCTCCCGAACAGGTGCAGGCTGCATTCGATGACGTGCTCAGGGCGGGTCAGGAG
CGTGAGCGCTCAAAGAACGAAGCCCAAGCCTATGCCAATGATGTGATTCCCCGCGCCGTGGGTTCAGCTTCACGCCTCAA
GGAGGAGTCGGAAGCTTACAAGGCGCGAATTGTGGCGCAGGCCCAGGGTGATGCCCAGCGTTTCCGCTCGGTGCTGACCG
AATACCAGAAGGCGCCTCAGGTCACCCGCGATCGCATGTACCTGGATGCCATGCAGCAGGTCTACACCAATGTCACCAAG
GTGCTGGTGGAGTCCCGCCAGGGCTCCAACCTGCTGTATCTTCCGCTCGACAAGATCATGCAGATGACCGCGCAGGGTGG
TGCAGCGGCAGGCGCCGAGATCCCGCTACTGCCGGGCAGTGGAACGGCACCGCCCGCCGCGGCCCCTTCGCCGTCGGGTG
GTAGCCTGCCCCTGGATGCCCGTTCACGCGATGCTTCCCGCACCCGCGACCGTGAAACACGCTAA

Upstream 100 bases:

>100_bases
GTGACCGGAGAAATTCTCCAAACAGCCGACGACCTTGCCTGATCGGGCAATTTCATTAGGCACAATGTCGGTGTAGTCAA
AAATAAGCGAGTTTGATCCC

Downstream 100 bases:

>100_bases
GGAAGAAAAACGTGAATAGAGTTGGATTTTTCGTATCTTCATTGCTGGTGGTGCTGGCGCTGCTGAGTTCCACCCTGTTT
GTCGTCGACCAGCGTCAGTT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNLNPVLQTLTTLPGRLKQRAQGMFNLNDPRWGRDDDKPSSDETKPDMPRDDKQPSRPVRPQGQGPNQGPPDLDELWRDF
NRKLGGLFGGAKSAGKRGGFGGGNNGGDGGNGGGFQPDMKSAGIGAGLIAAVAVLIWLGTGFFIVQEGQQAVITQFGKYH
STVGAGFNWRLPYPVQRHEMVVVTQIRSVDVGRDTIIKATGLRDSAMLTEDENIVEIKFAVQYRLSDARAYLFESKDPAS
AVVQAAETAVREVVGKMKMDLALADERDQIGPRVRALMQIILDRYKVGVEVVGINLQQSGVRPPEQVQAAFDDVLRAGQE
RERSKNEAQAYANDVIPRAVGSASRLKEESEAYKARIVAQAQGDAQRFRSVLTEYQKAPQVTRDRMYLDAMQQVYTNVTK
VLVESRQGSNLLYLPLDKIMQMTAQGGAAAGAEIPLLPGSGTAPPAAAPSPSGGSLPLDARSRDASRTRDRETR

Sequences:

>Translated_474_residues
MNLNPVLQTLTTLPGRLKQRAQGMFNLNDPRWGRDDDKPSSDETKPDMPRDDKQPSRPVRPQGQGPNQGPPDLDELWRDF
NRKLGGLFGGAKSAGKRGGFGGGNNGGDGGNGGGFQPDMKSAGIGAGLIAAVAVLIWLGTGFFIVQEGQQAVITQFGKYH
STVGAGFNWRLPYPVQRHEMVVVTQIRSVDVGRDTIIKATGLRDSAMLTEDENIVEIKFAVQYRLSDARAYLFESKDPAS
AVVQAAETAVREVVGKMKMDLALADERDQIGPRVRALMQIILDRYKVGVEVVGINLQQSGVRPPEQVQAAFDDVLRAGQE
RERSKNEAQAYANDVIPRAVGSASRLKEESEAYKARIVAQAQGDAQRFRSVLTEYQKAPQVTRDRMYLDAMQQVYTNVTK
VLVESRQGSNLLYLPLDKIMQMTAQGGAAAGAEIPLLPGSGTAPPAAAPSPSGGSLPLDARSRDASRTRDRETR
>Mature_474_residues
MNLNPVLQTLTTLPGRLKQRAQGMFNLNDPRWGRDDDKPSSDETKPDMPRDDKQPSRPVRPQGQGPNQGPPDLDELWRDF
NRKLGGLFGGAKSAGKRGGFGGGNNGGDGGNGGGFQPDMKSAGIGAGLIAAVAVLIWLGTGFFIVQEGQQAVITQFGKYH
STVGAGFNWRLPYPVQRHEMVVVTQIRSVDVGRDTIIKATGLRDSAMLTEDENIVEIKFAVQYRLSDARAYLFESKDPAS
AVVQAAETAVREVVGKMKMDLALADERDQIGPRVRALMQIILDRYKVGVEVVGINLQQSGVRPPEQVQAAFDDVLRAGQE
RERSKNEAQAYANDVIPRAVGSASRLKEESEAYKARIVAQAQGDAQRFRSVLTEYQKAPQVTRDRMYLDAMQQVYTNVTK
VLVESRQGSNLLYLPLDKIMQMTAQGGAAAGAEIPLLPGSGTAPPAAAPSPSGGSLPLDARSRDASRTRDRETR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=294, Percent_Identity=36.3945578231293, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 51470; Mature: 51470

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNPVLQTLTTLPGRLKQRAQGMFNLNDPRWGRDDDKPSSDETKPDMPRDDKQPSRPVR
CCCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQGQGPNQGPPDLDELWRDFNRKLGGLFGGAKSAGKRGGFGGGNNGGDGGNGGGFQPDMK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
SAGIGAGLIAAVAVLIWLGTGFFIVQEGQQAVITQFGKYHSTVGAGFNWRLPYPVQRHEM
HCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VVVTQIRSVDVGRDTIIKATGLRDSAMLTEDENIVEIKFAVQYRLSDARAYLFESKDPAS
EEEEEHHHCCCCCHHEEEECCCCCCCEECCCCCEEEEEEEEEEEHHHHHHEEECCCCHHH
AVVQAAETAVREVVGKMKMDLALADERDQIGPRVRALMQIILDRYKVGVEVVGINLQQSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEHHCC
VRPPEQVQAAFDDVLRAGQERERSKNEAQAYANDVIPRAVGSASRLKEESEAYKARIVAQ
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQGDAQRFRSVLTEYQKAPQVTRDRMYLDAMQQVYTNVTKVLVESRQGSNLLYLPLDKIM
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHH
QMTAQGGAAAGAEIPLLPGSGTAPPAAAPSPSGGSLPLDARSRDASRTRDRETR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MNLNPVLQTLTTLPGRLKQRAQGMFNLNDPRWGRDDDKPSSDETKPDMPRDDKQPSRPVR
CCCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQGQGPNQGPPDLDELWRDFNRKLGGLFGGAKSAGKRGGFGGGNNGGDGGNGGGFQPDMK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
SAGIGAGLIAAVAVLIWLGTGFFIVQEGQQAVITQFGKYHSTVGAGFNWRLPYPVQRHEM
HCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VVVTQIRSVDVGRDTIIKATGLRDSAMLTEDENIVEIKFAVQYRLSDARAYLFESKDPAS
EEEEEHHHCCCCCHHEEEECCCCCCCEECCCCCEEEEEEEEEEEHHHHHHEEECCCCHHH
AVVQAAETAVREVVGKMKMDLALADERDQIGPRVRALMQIILDRYKVGVEVVGINLQQSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCEEEEEEEEHHCC
VRPPEQVQAAFDDVLRAGQERERSKNEAQAYANDVIPRAVGSASRLKEESEAYKARIVAQ
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQGDAQRFRSVLTEYQKAPQVTRDRMYLDAMQQVYTNVTKVLVESRQGSNLLYLPLDKIM
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHH
QMTAQGGAAAGAEIPLLPGSGTAPPAAAPSPSGGSLPLDARSRDASRTRDRETR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]