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The map label for this gene is zupT [H]

Identifier: 91788357

GI number: 91788357

Start: 2612662

End: 2613453

Strand: Direct

Name: zupT [H]

Synonym: Bpro_2494

Alternate gene names: 91788357

Gene position: 2612662-2613453 (Clockwise)

Preceding gene: 91788356

Following gene: 91788358

Centisome position: 50.24

GC content: 65.4

Gene sequence:

>792_bases
ATGCTGCTCGCTTCCATCGTAATGGCCTGCTTGCTGGGCGGCGTCCTGAGTGTGGTCGTTGCAGGTTTCCTGCTGAAGGG
TTTGCCGCAGCACTGGCTGCCGCGCATGGTCGGCTTCTCGGCGGGCTTGCTGCTGGGCGCCGCAATGCTCTCGGTCCTGC
CCGAGGCCTTTGAATCGGGGGCCGATGCCCATACGCTGTTTGTCGTGCTGCTGGCAGGGTTCGTCGGCTTTTATGCGCTG
CAGCGCACGGCGCTCTGGCGCCATAGCCACAGCACGCCGGATGAGGCCGGCCAATCGACCCAGACGCACACCCATCACAC
GCACGCCCACGCCCCTGGCCTGGGGCGGGAAACCGTGCTGACCGTGTTGATCGGCGACGGTTTTCATAATTTTGTCGACG
GCGTCCTGATTGCGGCCGCTTTTCTGACGGACCCTGCGCTCGGCTGGGCGACCGCGATCGCCGTCATCGCCCATGAGATC
CCGCAGGAGGCCGGGGATTTTGTGCTGCTGCTGGCCTCTGGCTTGGGCTTTCGCCGGGCGCTGGCGCTCAATGCGCTGTC
CGGACTGGCGTCGGTGCTGGGTGGCCTGGTCGGGTATTGGGGCCTTTCGCATGCGCAGGCTTTTTTGCCTTATGCGCTGG
TGTTGGCGGCCGCCAGCTTTATCTACATCGCCATTGCGGATTTGCTGCCGTACCTGCGCCGCGAGCCTGCTGGCGCGCAG
ATCGCCTGGCAGACCGTGGCGCTGACGGCCGGTCTGGTGGCTGCTGCGTGGCTATCTGCGTCTCACGGATGA

Upstream 100 bases:

>100_bases
GATCGCGCGCCGCGCGCCCTATGTTTCCGGCGGGCTCATCCTGCTGGTCGGCCTGTATGTCGGATACCACGGCTACATCG
GCCTGGCCGGAGGCTAAGCC

Downstream 100 bases:

>100_bases
CTCGCACAGGCTGAACCGCGCAGGCTCCATGGGCTACCATCTCCCAAAAAGGAGACAAGGATGAACATTCAACCAGCGCG
GACCACTTGCATGCAAATGA

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLLASIVMACLLGGVLSVVVAGFLLKGLPQHWLPRMVGFSAGLLLGAAMLSVLPEAFESGADAHTLFVVLLAGFVGFYAL
QRTALWRHSHSTPDEAGQSTQTHTHHTHAHAPGLGRETVLTVLIGDGFHNFVDGVLIAAAFLTDPALGWATAIAVIAHEI
PQEAGDFVLLLASGLGFRRALALNALSGLASVLGGLVGYWGLSHAQAFLPYALVLAAASFIYIAIADLLPYLRREPAGAQ
IAWQTVALTAGLVAAAWLSASHG

Sequences:

>Translated_263_residues
MLLASIVMACLLGGVLSVVVAGFLLKGLPQHWLPRMVGFSAGLLLGAAMLSVLPEAFESGADAHTLFVVLLAGFVGFYAL
QRTALWRHSHSTPDEAGQSTQTHTHHTHAHAPGLGRETVLTVLIGDGFHNFVDGVLIAAAFLTDPALGWATAIAVIAHEI
PQEAGDFVLLLASGLGFRRALALNALSGLASVLGGLVGYWGLSHAQAFLPYALVLAAASFIYIAIADLLPYLRREPAGAQ
IAWQTVALTAGLVAAAWLSASHG
>Mature_263_residues
MLLASIVMACLLGGVLSVVVAGFLLKGLPQHWLPRMVGFSAGLLLGAAMLSVLPEAFESGADAHTLFVVLLAGFVGFYAL
QRTALWRHSHSTPDEAGQSTQTHTHHTHAHAPGLGRETVLTVLIGDGFHNFVDGVLIAAAFLTDPALGWATAIAVIAHEI
PQEAGDFVLLLASGLGFRRALALNALSGLASVLGGLVGYWGLSHAQAFLPYALVLAAASFIYIAIADLLPYLRREPAGAQ
IAWQTVALTAGLVAAAWLSASHG

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI187936949, Length=109, Percent_Identity=39.4495412844037, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI55741750, Length=109, Percent_Identity=39.4495412844037, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI223633937, Length=113, Percent_Identity=36.283185840708, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI223633939, Length=113, Percent_Identity=36.283185840708, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI153252201, Length=111, Percent_Identity=38.7387387387387, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI205830426, Length=119, Percent_Identity=36.9747899159664, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI153252214, Length=110, Percent_Identity=38.1818181818182, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI190358541, Length=113, Percent_Identity=37.1681415929204, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI205830424, Length=113, Percent_Identity=37.1681415929204, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI190360568, Length=113, Percent_Identity=37.1681415929204, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI205830405, Length=132, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40255101, Length=282, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI190014617, Length=286, Percent_Identity=27.972027972028, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI205830407, Length=127, Percent_Identity=33.8582677165354, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI206597541, Length=134, Percent_Identity=40.2985074626866, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI206597539, Length=134, Percent_Identity=40.2985074626866, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI24586665, Length=127, Percent_Identity=33.8582677165354, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI205830403, Length=127, Percent_Identity=33.8582677165354, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI117553619, Length=119, Percent_Identity=37.8151260504202, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI117553608, Length=119, Percent_Identity=37.8151260504202, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI115430255, Length=113, Percent_Identity=37.1681415929204, Blast_Score=64, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193209531, Length=231, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71998183, Length=150, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538884, Length=109, Percent_Identity=40.3669724770642, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994730, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566718, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32566720, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71992548, Length=134, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322166, Length=223, Percent_Identity=29.5964125560538, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161083817, Length=111, Percent_Identity=45.945945945946, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24664383, Length=111, Percent_Identity=45.945945945946, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45549201, Length=111, Percent_Identity=38.7387387387387, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17864610, Length=153, Percent_Identity=28.7581699346405, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27380; Mature: 27380

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLASIVMACLLGGVLSVVVAGFLLKGLPQHWLPRMVGFSAGLLLGAAMLSVLPEAFESG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADAHTLFVVLLAGFVGFYALQRTALWRHSHSTPDEAGQSTQTHTHHTHAHAPGLGRETVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHH
TVLIGDGFHNFVDGVLIAAAFLTDPALGWATAIAVIAHEIPQEAGDFVLLLASGLGFRRA
HHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCHHHH
LALNALSGLASVLGGLVGYWGLSHAQAFLPYALVLAAASFIYIAIADLLPYLRREPAGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
IAWQTVALTAGLVAAAWLSASHG
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLASIVMACLLGGVLSVVVAGFLLKGLPQHWLPRMVGFSAGLLLGAAMLSVLPEAFESG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADAHTLFVVLLAGFVGFYALQRTALWRHSHSTPDEAGQSTQTHTHHTHAHAPGLGRETVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHH
TVLIGDGFHNFVDGVLIAAAFLTDPALGWATAIAVIAHEIPQEAGDFVLLLASGLGFRRA
HHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCHHHH
LALNALSGLASVLGGLVGYWGLSHAQAFLPYALVLAAASFIYIAIADLLPYLRREPAGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
IAWQTVALTAGLVAAAWLSASHG
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA