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The map label for this gene is ldcA [H]

Identifier: 91788313

GI number: 91788313

Start: 2550872

End: 2551822

Strand: Direct

Name: ldcA [H]

Synonym: Bpro_2448

Alternate gene names: 91788313

Gene position: 2550872-2551822 (Clockwise)

Preceding gene: 91788312

Following gene: 91788315

Centisome position: 49.05

GC content: 59.94

Gene sequence:

>951_bases
GTGAAAAAACATATCTACATTTACTCGCCTTCCAGCGCCGTGCGCGACAAAGCGAGCTTCAAACGCGGCGTTCGGCGCCT
GACGGCACTGGGCCATGAGGTTGAAATTGACGAAGCTGCGCTGGCCAGGCACCAGCGTTTTGCCGGCGATGACGAAACCC
GGCTGGCGGCCATCCACCGCGCGGCTGCCAGCGGCGCCGATGTGGCTCTCATTACCCGCGGCGGCTACGGCCTTACGCGC
ATCCTGCCGGGCATCAACTACAAGGCTGTGGCCAAGGCCATCGACAAGGGCACGCAATTTGTGGGCCTCAGTGATTTCAC
GGCGTTTCAGTCGGCTGTGCTGGCCAAAACCGGTGCGGTCACGTGGGCGGGGCCTGCGCTGGGCGAAGACTTTGGCACCG
AGGTCCCTCCCGACGACATCATGGAAGCCTGTTTTGACGACCTGATCACGGGTCAGGGCGAGGGCACCGGCTGGCAACTC
CCGAAATCCGCCATGAATTCAATAGCCGACAACCCGGATTTGAAGGGGGCTGAAACTCAATTCAGCATCAAGAATGCCGT
GCTGTGGGGAGGCAACCTGGCGATTTTGTCGTCCTTGGTGGGAACGCCCTACCTACCCATCGTCAAGGGCGGTATTTTGT
TTGTCGAAGATGTTGGCGAGCATCCCTACCGGGTGGAGCGCATGTTCACGCAACTGCTGTATGCGGGTGTGCTGGCACAG
CAAAAGGCGGTCATTTTTGGGCAGTTCACCAATTACAGGCTGGTGCCGCATGACAAGGGTTTCAAATTACCTTCGGTGGC
AGCCTGGCTACAGAGCCAGATCAAGGCGCCGGTGCTGACCGGACTGCCGTTTGGCCACGTGGCGACCAAGGTGCTGCTGC
CCGTGGGCTACAAAACAACGTTGGCGGTGGAGGGCAGGGATGCGTTTTTGCTGTGGGGCCACCAGCATTAG

Upstream 100 bases:

>100_bases
AGGAGCACGGGGAGCCGATTGCCCGGCATGCGGTCGGCTTCTTCAAACGGTGACCTGAAACCACGCGTGAATGCTGATCA
GCAATGGGATACTCCTGCCT

Downstream 100 bases:

>100_bases
GCTGATGATCCAACCCACTGGCAGTCCCGCTCGCATGAGGGCGTACTGACGCGAAAGTCCAAAAATAAACCAGCACGAGG
CTGGTTGATGGGTGTCAGGT

Product: muramoyltetrapeptide carboxypeptidase

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKKHIYIYSPSSAVRDKASFKRGVRRLTALGHEVEIDEAALARHQRFAGDDETRLAAIHRAAASGADVALITRGGYGLTR
ILPGINYKAVAKAIDKGTQFVGLSDFTAFQSAVLAKTGAVTWAGPALGEDFGTEVPPDDIMEACFDDLITGQGEGTGWQL
PKSAMNSIADNPDLKGAETQFSIKNAVLWGGNLAILSSLVGTPYLPIVKGGILFVEDVGEHPYRVERMFTQLLYAGVLAQ
QKAVIFGQFTNYRLVPHDKGFKLPSVAAWLQSQIKAPVLTGLPFGHVATKVLLPVGYKTTLAVEGRDAFLLWGHQH

Sequences:

>Translated_316_residues
MKKHIYIYSPSSAVRDKASFKRGVRRLTALGHEVEIDEAALARHQRFAGDDETRLAAIHRAAASGADVALITRGGYGLTR
ILPGINYKAVAKAIDKGTQFVGLSDFTAFQSAVLAKTGAVTWAGPALGEDFGTEVPPDDIMEACFDDLITGQGEGTGWQL
PKSAMNSIADNPDLKGAETQFSIKNAVLWGGNLAILSSLVGTPYLPIVKGGILFVEDVGEHPYRVERMFTQLLYAGVLAQ
QKAVIFGQFTNYRLVPHDKGFKLPSVAAWLQSQIKAPVLTGLPFGHVATKVLLPVGYKTTLAVEGRDAFLLWGHQH
>Mature_316_residues
MKKHIYIYSPSSAVRDKASFKRGVRRLTALGHEVEIDEAALARHQRFAGDDETRLAAIHRAAASGADVALITRGGYGLTR
ILPGINYKAVAKAIDKGTQFVGLSDFTAFQSAVLAKTGAVTWAGPALGEDFGTEVPPDDIMEACFDDLITGQGEGTGWQL
PKSAMNSIADNPDLKGAETQFSIKNAVLWGGNLAILSSLVGTPYLPIVKGGILFVEDVGEHPYRVERMFTQLLYAGVLAQ
QKAVIFGQFTNYRLVPHDKGFKLPSVAAWLQSQIKAPVLTGLPFGHVATKVLLPVGYKTTLAVEGRDAFLLWGHQH

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=299, Percent_Identity=36.7892976588629, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 34071; Mature: 34071

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHIYIYSPSSAVRDKASFKRGVRRLTALGHEVEIDEAALARHQRFAGDDETRLAAIHR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AAASGADVALITRGGYGLTRILPGINYKAVAKAIDKGTQFVGLSDFTAFQSAVLAKTGAV
HHCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCC
TWAGPALGEDFGTEVPPDDIMEACFDDLITGQGEGTGWQLPKSAMNSIADNPDLKGAETQ
EECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCE
FSIKNAVLWGGNLAILSSLVGTPYLPIVKGGILFVEDVGEHPYRVERMFTQLLYAGVLAQ
EEEEEEEEECCHHHHHHHHHCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QKAVIFGQFTNYRLVPHDKGFKLPSVAAWLQSQIKAPVLTGLPFGHVATKVLLPVGYKTT
CCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCEEE
LAVEGRDAFLLWGHQH
EEECCCCEEEEECCCC
>Mature Secondary Structure
MKKHIYIYSPSSAVRDKASFKRGVRRLTALGHEVEIDEAALARHQRFAGDDETRLAAIHR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AAASGADVALITRGGYGLTRILPGINYKAVAKAIDKGTQFVGLSDFTAFQSAVLAKTGAV
HHCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCC
TWAGPALGEDFGTEVPPDDIMEACFDDLITGQGEGTGWQLPKSAMNSIADNPDLKGAETQ
EECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCE
FSIKNAVLWGGNLAILSSLVGTPYLPIVKGGILFVEDVGEHPYRVERMFTQLLYAGVLAQ
EEEEEEEEECCHHHHHHHHHCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QKAVIFGQFTNYRLVPHDKGFKLPSVAAWLQSQIKAPVLTGLPFGHVATKVLLPVGYKTT
CCEEEEEECCCCEECCCCCCCCCHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCEEE
LAVEGRDAFLLWGHQH
EEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]