Click here to switch to the map view.

The map label for this gene is dsbB

Identifier: 91788252

GI number: 91788252

Start: 2477296

End: 2477802

Strand: Direct

Name: dsbB

Synonym: Bpro_2385

Alternate gene names: 91788252

Gene position: 2477296-2477802 (Clockwise)

Preceding gene: 91788246

Following gene: 91788253

Centisome position: 47.64

GC content: 59.37

Gene sequence:

>507_bases
ATGTTTTTGACGTATTTCGACGCCATGCCACGCCGTGTGCTTGCCCTGGTGTCCCTGGCCTGTGTGGCCCTGCTGGCTTT
TGGCTTGTACCTGCAGCATGTCGTTGGCCTGGAGCCTTGCCCCATGTGCATCGTGCAGCGTTATGCGCTGGTGCTGGTGG
CTGTGGTTGCAGGCATCACGGCGGTGGCAAAAAGCAGGGGGCTGCTGATCACGGGCTCGGGCTTGCTGGTGCTGCTTTCC
GGCTTTGGTGCATTTGTGGCGGCCCGCCAGAGTTTTCTGCAGTGGTACCCGCCTGAAGTGGCCTCCTGCGGCCGTGACTT
TTACGGAATGATCGAAACCTTTCCGCTCAAGCGCGCGATTCCCATGATCTTCAAGGGCAGTGGCGACTGCACCAAAATTG
ACTGGACCTTTCTGGGCCTGTCGATTGCCAACTGGTCTTTCCTGTGCTTTGTGGCGATTGCCTTGGTGGGACTGGTCCTG
ATCACCCGCCTGGCTCGTCAGCGCTGA

Upstream 100 bases:

>100_bases
ACCCGTCCTGCCAATCAGATTTCCTCGCTCGGGAACTTATCCCCTGCCAAACCCACGAACCATCGGACAATTCACAATCA
ATCCAAAAAGAGGGTTCCCG

Downstream 100 bases:

>100_bases
GGGCGGCGCTTTCTCTTTCTCCTCGGGCGCCGGGTCGATTGCACCCTGGCGCTTTTCGTTTTCACGTTTTTCTTTCATGA
GATCAGTCCGTTAAACGGGC

Product: disulfide bond formation protein DsbB

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MFLTYFDAMPRRVLALVSLACVALLAFGLYLQHVVGLEPCPMCIVQRYALVLVAVVAGITAVAKSRGLLITGSGLLVLLS
GFGAFVAARQSFLQWYPPEVASCGRDFYGMIETFPLKRAIPMIFKGSGDCTKIDWTFLGLSIANWSFLCFVAIALVGLVL
ITRLARQR

Sequences:

>Translated_168_residues
MFLTYFDAMPRRVLALVSLACVALLAFGLYLQHVVGLEPCPMCIVQRYALVLVAVVAGITAVAKSRGLLITGSGLLVLLS
GFGAFVAARQSFLQWYPPEVASCGRDFYGMIETFPLKRAIPMIFKGSGDCTKIDWTFLGLSIANWSFLCFVAIALVGLVL
ITRLARQR
>Mature_168_residues
MFLTYFDAMPRRVLALVSLACVALLAFGLYLQHVVGLEPCPMCIVQRYALVLVAVVAGITAVAKSRGLLITGSGLLVLLS
GFGAFVAARQSFLQWYPPEVASCGRDFYGMIETFPLKRAIPMIFKGSGDCTKIDWTFLGLSIANWSFLCFVAIALVGLVL
ITRLARQR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=147, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_POLSJ (Q12AY6)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549204.1
- ProteinModelPortal:   Q12AY6
- SMR:   Q12AY6
- STRING:   Q12AY6
- GeneID:   4014960
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2385
- NMPDR:   fig|296591.1.peg.3689
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   FICFAIM
- PhylomeDB:   Q12AY6
- ProtClustDB:   CLSK951409
- BioCyc:   PSP296591:BPRO_2385-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 18327; Mature: 18327

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x138af00c)-; HASH(0x1466e1bc)-; HASH(0x13f68dcc)-; HASH(0x138d6624)-;

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTYFDAMPRRVLALVSLACVALLAFGLYLQHVVGLEPCPMCIVQRYALVLVAVVAGIT
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AVAKSRGLLITGSGLLVLLSGFGAFVAARQSFLQWYPPEVASCGRDFYGMIETFPLKRAI
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHH
PMIFKGSGDCTKIDWTFLGLSIANWSFLCFVAIALVGLVLITRLARQR
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFLTYFDAMPRRVLALVSLACVALLAFGLYLQHVVGLEPCPMCIVQRYALVLVAVVAGIT
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AVAKSRGLLITGSGLLVLLSGFGAFVAARQSFLQWYPPEVASCGRDFYGMIETFPLKRAI
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHH
PMIFKGSGDCTKIDWTFLGLSIANWSFLCFVAIALVGLVLITRLARQR
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA