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The map label for this gene is rbsK [H]

Identifier: 91788078

GI number: 91788078

Start: 2301990

End: 2302973

Strand: Reverse

Name: rbsK [H]

Synonym: Bpro_2205

Alternate gene names: 91788078

Gene position: 2302973-2301990 (Counterclockwise)

Preceding gene: 91788079

Following gene: 91788075

Centisome position: 44.29

GC content: 69.51

Gene sequence:

>984_bases
GTGAGCCACCCGGATAGCCCCGCCGGCGCCGCAGAGCCCGTAGCAATAACAGCCACCGAAGCGCCTGCCGAGGTGGTCTG
CGTGGCCAGCTGGAATGCCGACCTGGTGTCGCACGTGGCACGGCCTATCGCTCGCGGCGAGACGCTGATGGCCAGTGCAT
TCAGCATCAGCCCCGGCGGCAAAGGCAGCAATGCGGCCGTCGCTGCCGCCCGCCAGGGCGCGCGCGTAGCGCTCATCGCC
CGCATCGGCGACGACGACTTCGGGCGTATGGGCATGACGCTGTGGCATGCCGAAGGCGTCGCCACCGACCATGTCGAGCA
CGCCGCCGGCGAATGCAGCGGCGTGGCCCAGATCCTGGTGTATGACGATGGCGACAACAGCATTGCTGTCTGCCCCGGCG
CCGGCTCCGGCCTGGGCGCATCGCAGGTACAGGCGGCCCATGGTGTGCTGCGCAGCTGCCGCGTCGTGATGGCGTCCTGC
GAGGTGCCTGTAGAGGCCACGCTGCAGGCCTTCCGGCTGGCCCGCGAAGCCGGGGCCATCACCCTGCTGAACCCCGCGCC
GGCACGTCCCCTGCCTGAGGAGTTGCTGGCACTGGTCGACGTTCTCACGCCGAACGAAAGCGAGCTGTATCAGCTCGCCG
GTGCGGAGCACTCAGGATCGTTGGACGCCGCCGCAAATCACCTGCTGGCAGGCGGAACCGGTGCGGTGCTGGTGACGCTG
GGCGCTGCCGGCTGTCGCCTTTATCAAGGCAGACAGACCCCGATCGGCCTGGCCGGACGCAGCATGCCCGTGCTGGACAC
CATAGGCGCAGGCGACACCTTCACCGGTACGCTGGCAGCGGCCCTGGCACGCGGCGAGCCACTCGCGAGCGCCATGCAAT
GGGCCAATGCCGCGGCGGCCCTGTCAGTGACCAGGCGTGGCGCGATCGACGGCATTCCGGCACGCGCAGACGTTGCGGCC
CTGATGAGCCAGGTCGCCAGGTAA

Upstream 100 bases:

>100_bases
GGCATTTCCTGGTCATGCTGCTGCTCTTGCTGCTCGCCATGACCTGCTTTCCACAAATTGTGCTGTGGCTGCCGCAAACC
ATGGGCTACGGAGGCAAATA

Downstream 100 bases:

>100_bases
TCTCCCCGATGCGGGCAGCTGGTTAGCCAATCAGCCCTTTTGCAAAATCCATGCGGCCGCACACACACTTTTTATAGCGC
GCAGCACTTCACCTGGGCCT

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSHPDSPAGAAEPVAITATEAPAEVVCVASWNADLVSHVARPIARGETLMASAFSISPGGKGSNAAVAAARQGARVALIA
RIGDDDFGRMGMTLWHAEGVATDHVEHAAGECSGVAQILVYDDGDNSIAVCPGAGSGLGASQVQAAHGVLRSCRVVMASC
EVPVEATLQAFRLAREAGAITLLNPAPARPLPEELLALVDVLTPNESELYQLAGAEHSGSLDAAANHLLAGGTGAVLVTL
GAAGCRLYQGRQTPIGLAGRSMPVLDTIGAGDTFTGTLAAALARGEPLASAMQWANAAAALSVTRRGAIDGIPARADVAA
LMSQVAR

Sequences:

>Translated_327_residues
MSHPDSPAGAAEPVAITATEAPAEVVCVASWNADLVSHVARPIARGETLMASAFSISPGGKGSNAAVAAARQGARVALIA
RIGDDDFGRMGMTLWHAEGVATDHVEHAAGECSGVAQILVYDDGDNSIAVCPGAGSGLGASQVQAAHGVLRSCRVVMASC
EVPVEATLQAFRLAREAGAITLLNPAPARPLPEELLALVDVLTPNESELYQLAGAEHSGSLDAAANHLLAGGTGAVLVTL
GAAGCRLYQGRQTPIGLAGRSMPVLDTIGAGDTFTGTLAAALARGEPLASAMQWANAAAALSVTRRGAIDGIPARADVAA
LMSQVAR
>Mature_326_residues
SHPDSPAGAAEPVAITATEAPAEVVCVASWNADLVSHVARPIARGETLMASAFSISPGGKGSNAAVAAARQGARVALIAR
IGDDDFGRMGMTLWHAEGVATDHVEHAAGECSGVAQILVYDDGDNSIAVCPGAGSGLGASQVQAAHGVLRSCRVVMASCE
VPVEATLQAFRLAREAGAITLLNPAPARPLPEELLALVDVLTPNESELYQLAGAEHSGSLDAAANHLLAGGTGAVLVTLG
AAGCRLYQGRQTPIGLAGRSMPVLDTIGAGDTFTGTLAAALARGEPLASAMQWANAAAALSVTRRGAIDGIPARADVAAL
MSQVAR

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=295, Percent_Identity=34.5762711864407, Blast_Score=145, Evalue=7e-35,
Organism=Escherichia coli, GI1790193, Length=305, Percent_Identity=37.7049180327869, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI87081971, Length=311, Percent_Identity=27.9742765273312, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=32.9896907216495, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788491, Length=289, Percent_Identity=24.5674740484429, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=296, Percent_Identity=33.7837837837838, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=37.5, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=28.1456953642384, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32859; Mature: 32727

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPDSPAGAAEPVAITATEAPAEVVCVASWNADLVSHVARPIARGETLMASAFSISPGG
CCCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCC
KGSNAAVAAARQGARVALIARIGDDDFGRMGMTLWHAEGVATDHVEHAAGECSGVAQILV
CCCCHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEE
YDDGDNSIAVCPGAGSGLGASQVQAAHGVLRSCRVVMASCEVPVEATLQAFRLAREAGAI
EECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
TLLNPAPARPLPEELLALVDVLTPNESELYQLAGAEHSGSLDAAANHLLAGGTGAVLVTL
EEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEE
GAAGCRLYQGRQTPIGLAGRSMPVLDTIGAGDTFTGTLAAALARGEPLASAMQWANAAAA
CCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSVTRRGAIDGIPARADVAALMSQVAR
HHHHHCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SHPDSPAGAAEPVAITATEAPAEVVCVASWNADLVSHVARPIARGETLMASAFSISPGG
CCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCC
KGSNAAVAAARQGARVALIARIGDDDFGRMGMTLWHAEGVATDHVEHAAGECSGVAQILV
CCCCHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEE
YDDGDNSIAVCPGAGSGLGASQVQAAHGVLRSCRVVMASCEVPVEATLQAFRLAREAGAI
EECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCE
TLLNPAPARPLPEELLALVDVLTPNESELYQLAGAEHSGSLDAAANHLLAGGTGAVLVTL
EEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEE
GAAGCRLYQGRQTPIGLAGRSMPVLDTIGAGDTFTGTLAAALARGEPLASAMQWANAAAA
CCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSVTRRGAIDGIPARADVAALMSQVAR
HHHHHCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]