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The map label for this gene is hipO [H]

Identifier: 91787984

GI number: 91787984

Start: 2200512

End: 2201708

Strand: Reverse

Name: hipO [H]

Synonym: Bpro_2111

Alternate gene names: 91787984

Gene position: 2201708-2200512 (Counterclockwise)

Preceding gene: 91787990

Following gene: 91787983

Centisome position: 42.34

GC content: 61.65

Gene sequence:

>1197_bases
ATGAAAGTCATTGACTCCATCGTCACGCAGGCCGCCGGCATTGCCGCTGTGCGCCGCGATATTCACGCCCACCCGGAACT
GTGCTTTGAAGAAGTGCGCACGGCCGATGTGGTGGCGCAAAAACTCACCGAATGGGGCATTCCCATGCATCGCGGCATGG
GCACCACCGGCGTGGTGGGCATCATCAAAAACGGCAGCTCGAATCGCGCCATCGGCCTGCGCGCCGACATGGACGCCTTG
CCGATGCAGGAGTTCAACACCTTCGAGCATGCCAGCCAGCACCCGGGCAAGATGCACGCCTGCGGCCACGATGGCCACAC
GGCCATGCTGCTGGCAGCCGCGCAGCACTTTGCCAAAAACCGCAATTTTGACGGCACCGTTTACCTGATTTTCCAGCCGG
CAGAAGAAGGCGGCGGCGGTGCGCGCGAGATGATCAAGGACGGCCTGTTTGACAAGTTCCCCATGGACGCCGTGTTCGGC
ATGCACAACTGGCCGGGCACGCAGGTCGGCAAGTTTGCCGCCAGCACCGGCCCGGTGATGGCGTCGAGCAATGAGTTCAA
GATCACGGTTCGCGGCAAGGGTGGCCATGCCGCCTTGCCGCACAACGGCATTGACCCGGTGCCCATCGCCTGCCAGATGG
TGCAGGCCTTCCAGACCATCATCAGCCGCAACAAGAAGCCGGTGGATGCCGGCGTGATCTCGGTCACCATGATCCATGCC
GGTGAGGCCACCAACGTGATTCCCGACAGCTGCGAGCTGCAGGGCACAGTGCGCACCTTCACGATCGAAGTGCTCGACAT
GATCGAAAAACGCATGAAACAGATCGCCGAGCATATTTGCGCCGCGCATGACGCCGAGTGCGAGTTCAGGTTTGTGCGCA
ACTACCCGCCCACCATCAACCACGCCAAAGAAACCGAGTTTGCGCGCAAGGTCATGGCCGAGATCGTTGGTGCGGACAAC
GTGATTGAGCAGGAGCCGACCATGGGAGCGGAAGACTTCTCCTACATGCTGCAGGCCAAACCAGGCTGCTATGCCTTTAT
TGCCAACGGCGACGGCACCCACCGCGAGATGGGTCACGGCGGGGGGCCATGCATGCTGCACAACCCGAGTTACGACTTCA
ATGACGACCTGATCCCGCTGGGCGCCACCTTCTGGGTGCGGCTGGCTGAAAGCTGGCTGGCCAAGGACGCTGCATGA

Upstream 100 bases:

>100_bases
GTTAAATCTGGCAGACTACGCGTGGTACAAAAGCCAACCCCGGGCTTGCAAAGCATCTGCGAACTAGCAGAGCGGCAGGC
CTGACCACCAAGAGGTTTTC

Downstream 100 bases:

>100_bases
TGGGCGTTACAGAGGCTTTTTCAAGCAGTTACGCGCAAGCCCGTGTCAAGTTCCTGGAGGCCGCTGCTGCTGCCGGCCTG
AAGGTGGACTCACACCTGCA

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKVIDSIVTQAAGIAAVRRDIHAHPELCFEEVRTADVVAQKLTEWGIPMHRGMGTTGVVGIIKNGSSNRAIGLRADMDAL
PMQEFNTFEHASQHPGKMHACGHDGHTAMLLAAAQHFAKNRNFDGTVYLIFQPAEEGGGGAREMIKDGLFDKFPMDAVFG
MHNWPGTQVGKFAASTGPVMASSNEFKITVRGKGGHAALPHNGIDPVPIACQMVQAFQTIISRNKKPVDAGVISVTMIHA
GEATNVIPDSCELQGTVRTFTIEVLDMIEKRMKQIAEHICAAHDAECEFRFVRNYPPTINHAKETEFARKVMAEIVGADN
VIEQEPTMGAEDFSYMLQAKPGCYAFIANGDGTHREMGHGGGPCMLHNPSYDFNDDLIPLGATFWVRLAESWLAKDAA

Sequences:

>Translated_398_residues
MKVIDSIVTQAAGIAAVRRDIHAHPELCFEEVRTADVVAQKLTEWGIPMHRGMGTTGVVGIIKNGSSNRAIGLRADMDAL
PMQEFNTFEHASQHPGKMHACGHDGHTAMLLAAAQHFAKNRNFDGTVYLIFQPAEEGGGGAREMIKDGLFDKFPMDAVFG
MHNWPGTQVGKFAASTGPVMASSNEFKITVRGKGGHAALPHNGIDPVPIACQMVQAFQTIISRNKKPVDAGVISVTMIHA
GEATNVIPDSCELQGTVRTFTIEVLDMIEKRMKQIAEHICAAHDAECEFRFVRNYPPTINHAKETEFARKVMAEIVGADN
VIEQEPTMGAEDFSYMLQAKPGCYAFIANGDGTHREMGHGGGPCMLHNPSYDFNDDLIPLGATFWVRLAESWLAKDAA
>Mature_398_residues
MKVIDSIVTQAAGIAAVRRDIHAHPELCFEEVRTADVVAQKLTEWGIPMHRGMGTTGVVGIIKNGSSNRAIGLRADMDAL
PMQEFNTFEHASQHPGKMHACGHDGHTAMLLAAAQHFAKNRNFDGTVYLIFQPAEEGGGGAREMIKDGLFDKFPMDAVFG
MHNWPGTQVGKFAASTGPVMASSNEFKITVRGKGGHAALPHNGIDPVPIACQMVQAFQTIISRNKKPVDAGVISVTMIHA
GEATNVIPDSCELQGTVRTFTIEVLDMIEKRMKQIAEHICAAHDAECEFRFVRNYPPTINHAKETEFARKVMAEIVGADN
VIEQEPTMGAEDFSYMLQAKPGCYAFIANGDGTHREMGHGGGPCMLHNPSYDFNDDLIPLGATFWVRLAESWLAKDAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=424, Percent_Identity=25.9433962264151, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787598, Length=327, Percent_Identity=25.0764525993884, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43283; Mature: 43283

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIDSIVTQAAGIAAVRRDIHAHPELCFEEVRTADVVAQKLTEWGIPMHRGMGTTGVVG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEE
IIKNGSSNRAIGLRADMDALPMQEFNTFEHASQHPGKMHACGHDGHTAMLLAAAQHFAKN
EEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHC
RNFDGTVYLIFQPAEEGGGGAREMIKDGLFDKFPMDAVFGMHNWPGTQVGKFAASTGPVM
CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCEE
ASSNEFKITVRGKGGHAALPHNGIDPVPIACQMVQAFQTIISRNKKPVDAGVISVTMIHA
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
GEATNVIPDSCELQGTVRTFTIEVLDMIEKRMKQIAEHICAAHDAECEFRFVRNYPPTIN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
HAKETEFARKVMAEIVGADNVIEQEPTMGAEDFSYMLQAKPGCYAFIANGDGTHREMGHG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHCCCC
GGPCMLHNPSYDFNDDLIPLGATFWVRLAESWLAKDAA
CCCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVIDSIVTQAAGIAAVRRDIHAHPELCFEEVRTADVVAQKLTEWGIPMHRGMGTTGVVG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEE
IIKNGSSNRAIGLRADMDALPMQEFNTFEHASQHPGKMHACGHDGHTAMLLAAAQHFAKN
EEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHC
RNFDGTVYLIFQPAEEGGGGAREMIKDGLFDKFPMDAVFGMHNWPGTQVGKFAASTGPVM
CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCEE
ASSNEFKITVRGKGGHAALPHNGIDPVPIACQMVQAFQTIISRNKKPVDAGVISVTMIHA
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
GEATNVIPDSCELQGTVRTFTIEVLDMIEKRMKQIAEHICAAHDAECEFRFVRNYPPTIN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
HAKETEFARKVMAEIVGADNVIEQEPTMGAEDFSYMLQAKPGCYAFIANGDGTHREMGHG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHCCCC
GGPCMLHNPSYDFNDDLIPLGATFWVRLAESWLAKDAA
CCCEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]