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The map label for this gene is pbpG [H]

Identifier: 91787957

GI number: 91787957

Start: 2168367

End: 2170394

Strand: Direct

Name: pbpG [H]

Synonym: Bpro_2084

Alternate gene names: 91787957

Gene position: 2168367-2170394 (Clockwise)

Preceding gene: 91787954

Following gene: 91787958

Centisome position: 41.7

GC content: 65.19

Gene sequence:

>2028_bases
ATGACCCCGGCCCTGCACCGCGCAGCCACTTTTACCGCTGAACAGTTCCACCGCCTCATGGGCGCCATCAGGCGGCACCC
CGTGCGGGCGGCTTTGGTGCTGCCGGCGCTGATGCTGCTTTATGTACTGGTGCTGATTCCGTTCACGCCCGGCATTGGCG
ACTTGCGCAAGGCCAAGTCTGAAACGCCCTCGGTGCTGCTGGCTTCTGATGGCACGGTGCTGGCCGAGTACAGGCGTATC
AACCGGCAGTGGGTGACGCTGGACAAGATTTCGCCCAACGTCGTTAACGCGCTGATCGCCACAGAAGACCACCGATTTTA
CGAGCACCACGGCATCGACTTCCGGCGTATCGCGGGGGCGGTGCTCAGTACCTTGTCGGGCGATTTGCAGGGTGGCTCGA
CCATCACGCAGCAGCTGGCGCGCAACTTGTACCCCGAGGAGATCGGCCGCGCCACCAGCATCACGCGCAAGGTCAAGGAG
GCGATCACCGCGCTGAAGATCGAGGCGGTGTATTCCAAGCGCGAGATCCTGGAGACCTATCTCAACACCGTGCCTTTTTT
GTACAACGCCTTCGGCATCGAAATGGCCGCGCGCACCTATTTCGACAAGTCGGCCTACAAGCTGGATGTGCTGGAGAGCG
CCACGCTGATCGGCATGCTCAAGGGCACGAGTTATTACAACCCGGTGTTGAACCCGGAGCGCGCCGTGCAGCGCCGCAAC
CTGGTGCTGGCGCAGATGGCCAAGCACGGCAAGCTGGACCCGGCCCGGGTTGAGGTGCTGGCCAAACGGCCGCTCAAGCT
AGACTTTGAGCGGCAGACCGAGGCGCTGGGCCCGGCGCCGCACGTGGCCCAACACTTGCGCAAATGGCTGATTGCCTGGG
CCGACCACAAGGGCTTCGACATTCATTCGGACGGCCTGCGGGTGCGCACCACCCTCGACGCCAAGATCCAGAAGGCGGCC
AACCAGGCGGTGGCCCGGCAGATGGCGCAATTGCAAACGCTGGCAGACGGCCGGCGCAAGGCGGGGCAGGAGCGGCCCGT
GCTGCAGGCCGGCTTCCTCGCGCTCGACCCGCGCAACGGCGCCGTGCGGGCCTGGGTGGGCAGCCGCGACTTTGCGCAGG
AGCAGTTTGACCATGTGAGCCAGGCGCGGCGCCAGCCGGGCTCGACCTTCAAGCCCTTTGTTTATGGCGCGGCCTTCATG
CTGGGGCTGGACCCGCTGGACACCTTGATCGACCAGCCTGTGGCCATCTCGCAGCAGGGCGCCGGGGTGTGGACGCCCAG
CGATGCAACGCCGCCCACTTACATGCCCACCACCCTGCGCGACGGGCTGGTGTATTCCAAAAACACCATCACGGCCCAGC
TGATGCAGAAGGTGGGGCCAGCCAAAGTAGGGGCGCTGGCGCAGGCCATGGGCGTGCGGCAGAGCAAGCTGGACCTGGTG
CCGTCACTCGCGCTGGGCACCAGCCCCGTCACGCTGCTGGAGATGGTCACCGCCTACGGCTCCATTGCCAATGGCGGCAG
TTATATGCCGCCGGTGCTGGTGCTGCGCGTGGAAGACCGCAACGGCCGGCTGCTGGAGCAGTTCGAGCCCGTCAGGGAGC
GCGAACCGGCCATGCCGCGTGCGCATGCGCTGACTTTGGTGAATGCGATGCGCGGTGTGATTGACGAGGGCACGGGCACG
GCCATTCGCCAGCGCTATGGCATCCAGGCCGACGTGGCCGGCAAGACCGGCACCACGCAAGACAACACCGACGGCTGGTT
CATCATGATGAACTCGCAACTGGTGGCCGGCGCCCGGGTCGGCTTTAACGACAACAGCGTGACCATGGGCACCTGGGGGC
AGGGTGCCCGCAGCGCGCTGCCCATGGTGGGCGAGGTTTTTCAGCAAGGCTTTCGCAACCGCTGGCTTGACCAGAACGCT
GAATTCGACATTCCGCGCCCACGGCCCGCTCCGCCGGAGCAGGCGCCGGTCATGGAGATCATGAATGGCTTGTTTGGCAG
GATCTTTCGGCAGTTGCAGGGGAACTGA

Upstream 100 bases:

>100_bases
AGCAGCTTATGGTGACCATTCCACGAGACTGCAGCCAGATGTAACACCGAAGGGTCGGCAAAGTTACAAACTGGGTTGAC
TGTCACCTTAAACTTGGTCC

Downstream 100 bases:

>100_bases
CTGAAGACGCTACAAAAAGGGTAGTTGCTTGCCGCCCGTGTTTATTGAGCTAGAGGCTTATTTGGCTTATTTGGCTAATA
AGTAAGCAACGCCTTCAAAC

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MTPALHRAATFTAEQFHRLMGAIRRHPVRAALVLPALMLLYVLVLIPFTPGIGDLRKAKSETPSVLLASDGTVLAEYRRI
NRQWVTLDKISPNVVNALIATEDHRFYEHHGIDFRRIAGAVLSTLSGDLQGGSTITQQLARNLYPEEIGRATSITRKVKE
AITALKIEAVYSKREILETYLNTVPFLYNAFGIEMAARTYFDKSAYKLDVLESATLIGMLKGTSYYNPVLNPERAVQRRN
LVLAQMAKHGKLDPARVEVLAKRPLKLDFERQTEALGPAPHVAQHLRKWLIAWADHKGFDIHSDGLRVRTTLDAKIQKAA
NQAVARQMAQLQTLADGRRKAGQERPVLQAGFLALDPRNGAVRAWVGSRDFAQEQFDHVSQARRQPGSTFKPFVYGAAFM
LGLDPLDTLIDQPVAISQQGAGVWTPSDATPPTYMPTTLRDGLVYSKNTITAQLMQKVGPAKVGALAQAMGVRQSKLDLV
PSLALGTSPVTLLEMVTAYGSIANGGSYMPPVLVLRVEDRNGRLLEQFEPVREREPAMPRAHALTLVNAMRGVIDEGTGT
AIRQRYGIQADVAGKTGTTQDNTDGWFIMMNSQLVAGARVGFNDNSVTMGTWGQGARSALPMVGEVFQQGFRNRWLDQNA
EFDIPRPRPAPPEQAPVMEIMNGLFGRIFRQLQGN

Sequences:

>Translated_675_residues
MTPALHRAATFTAEQFHRLMGAIRRHPVRAALVLPALMLLYVLVLIPFTPGIGDLRKAKSETPSVLLASDGTVLAEYRRI
NRQWVTLDKISPNVVNALIATEDHRFYEHHGIDFRRIAGAVLSTLSGDLQGGSTITQQLARNLYPEEIGRATSITRKVKE
AITALKIEAVYSKREILETYLNTVPFLYNAFGIEMAARTYFDKSAYKLDVLESATLIGMLKGTSYYNPVLNPERAVQRRN
LVLAQMAKHGKLDPARVEVLAKRPLKLDFERQTEALGPAPHVAQHLRKWLIAWADHKGFDIHSDGLRVRTTLDAKIQKAA
NQAVARQMAQLQTLADGRRKAGQERPVLQAGFLALDPRNGAVRAWVGSRDFAQEQFDHVSQARRQPGSTFKPFVYGAAFM
LGLDPLDTLIDQPVAISQQGAGVWTPSDATPPTYMPTTLRDGLVYSKNTITAQLMQKVGPAKVGALAQAMGVRQSKLDLV
PSLALGTSPVTLLEMVTAYGSIANGGSYMPPVLVLRVEDRNGRLLEQFEPVREREPAMPRAHALTLVNAMRGVIDEGTGT
AIRQRYGIQADVAGKTGTTQDNTDGWFIMMNSQLVAGARVGFNDNSVTMGTWGQGARSALPMVGEVFQQGFRNRWLDQNA
EFDIPRPRPAPPEQAPVMEIMNGLFGRIFRQLQGN
>Mature_674_residues
TPALHRAATFTAEQFHRLMGAIRRHPVRAALVLPALMLLYVLVLIPFTPGIGDLRKAKSETPSVLLASDGTVLAEYRRIN
RQWVTLDKISPNVVNALIATEDHRFYEHHGIDFRRIAGAVLSTLSGDLQGGSTITQQLARNLYPEEIGRATSITRKVKEA
ITALKIEAVYSKREILETYLNTVPFLYNAFGIEMAARTYFDKSAYKLDVLESATLIGMLKGTSYYNPVLNPERAVQRRNL
VLAQMAKHGKLDPARVEVLAKRPLKLDFERQTEALGPAPHVAQHLRKWLIAWADHKGFDIHSDGLRVRTTLDAKIQKAAN
QAVARQMAQLQTLADGRRKAGQERPVLQAGFLALDPRNGAVRAWVGSRDFAQEQFDHVSQARRQPGSTFKPFVYGAAFML
GLDPLDTLIDQPVAISQQGAGVWTPSDATPPTYMPTTLRDGLVYSKNTITAQLMQKVGPAKVGALAQAMGVRQSKLDLVP
SLALGTSPVTLLEMVTAYGSIANGGSYMPPVLVLRVEDRNGRLLEQFEPVREREPAMPRAHALTLVNAMRGVIDEGTGTA
IRQRYGIQADVAGKTGTTQDNTDGWFIMMNSQLVAGARVGFNDNSVTMGTWGQGARSALPMVGEVFQQGFRNRWLDQNAE
FDIPRPRPAPPEQAPVMEIMNGLFGRIFRQLQGN

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=535, Percent_Identity=33.6448598130841, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082258, Length=284, Percent_Identity=37.3239436619718, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788867, Length=577, Percent_Identity=29.6360485268631, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI1789601, Length=170, Percent_Identity=40.5882352941176, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 74453; Mature: 74322

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPALHRAATFTAEQFHRLMGAIRRHPVRAALVLPALMLLYVLVLIPFTPGIGDLRKAKS
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
ETPSVLLASDGTVLAEYRRINRQWVTLDKISPNVVNALIATEDHRFYEHHGIDFRRIAGA
CCCCEEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
VLSTLSGDLQGGSTITQQLARNLYPEEIGRATSITRKVKEAITALKIEAVYSKREILETY
HHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNTVPFLYNAFGIEMAARTYFDKSAYKLDVLESATLIGMLKGTSYYNPVLNPERAVQRRN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LVLAQMAKHGKLDPARVEVLAKRPLKLDFERQTEALGPAPHVAQHLRKWLIAWADHKGFD
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IHSDGLRVRTTLDAKIQKAANQAVARQMAQLQTLADGRRKAGQERPVLQAGFLALDPRNG
ECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEECCCCC
AVRAWVGSRDFAQEQFDHVSQARRQPGSTFKPFVYGAAFMLGLDPLDTLIDQPVAISQQG
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEECCCC
AGVWTPSDATPPTYMPTTLRDGLVYSKNTITAQLMQKVGPAKVGALAQAMGVRQSKLDLV
CCCCCCCCCCCCCCCCCHHHCCEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
PSLALGTSPVTLLEMVTAYGSIANGGSYMPPVLVLRVEDRNGRLLEQFEPVREREPAMPR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHCCHHHCCCCCCH
AHALTLVNAMRGVIDEGTGTAIRQRYGIQADVAGKTGTTQDNTDGWFIMMNSQLVAGARV
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEEECCCEEECEEE
GFNDNSVTMGTWGQGARSALPMVGEVFQQGFRNRWLDQNAEFDIPRPRPAPPEQAPVMEI
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MNGLFGRIFRQLQGN
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPALHRAATFTAEQFHRLMGAIRRHPVRAALVLPALMLLYVLVLIPFTPGIGDLRKAKS
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
ETPSVLLASDGTVLAEYRRINRQWVTLDKISPNVVNALIATEDHRFYEHHGIDFRRIAGA
CCCCEEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
VLSTLSGDLQGGSTITQQLARNLYPEEIGRATSITRKVKEAITALKIEAVYSKREILETY
HHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNTVPFLYNAFGIEMAARTYFDKSAYKLDVLESATLIGMLKGTSYYNPVLNPERAVQRRN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LVLAQMAKHGKLDPARVEVLAKRPLKLDFERQTEALGPAPHVAQHLRKWLIAWADHKGFD
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IHSDGLRVRTTLDAKIQKAANQAVARQMAQLQTLADGRRKAGQERPVLQAGFLALDPRNG
ECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEECCCCC
AVRAWVGSRDFAQEQFDHVSQARRQPGSTFKPFVYGAAFMLGLDPLDTLIDQPVAISQQG
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCEECCCC
AGVWTPSDATPPTYMPTTLRDGLVYSKNTITAQLMQKVGPAKVGALAQAMGVRQSKLDLV
CCCCCCCCCCCCCCCCCHHHCCEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHH
PSLALGTSPVTLLEMVTAYGSIANGGSYMPPVLVLRVEDRNGRLLEQFEPVREREPAMPR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHCCHHHCCCCCCH
AHALTLVNAMRGVIDEGTGTAIRQRYGIQADVAGKTGTTQDNTDGWFIMMNSQLVAGARV
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEEECCCEEECEEE
GFNDNSVTMGTWGQGARSALPMVGEVFQQGFRNRWLDQNAEFDIPRPRPAPPEQAPVMEI
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MNGLFGRIFRQLQGN
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]