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The map label for this gene is rlmH [H]

Identifier: 91787849

GI number: 91787849

Start: 2040066

End: 2040533

Strand: Direct

Name: rlmH [H]

Synonym: Bpro_1973

Alternate gene names: 91787849

Gene position: 2040066-2040533 (Clockwise)

Preceding gene: 91787848

Following gene: 91787850

Centisome position: 39.23

GC content: 63.46

Gene sequence:

>468_bases
ATGAGGCTGACGATCGTAGCGGTCGGCCAGAAGGTGCCCGACTGGGCGCAAACGGCTTACGACGACTACGCCAAGCGTTT
TCCGCCCGAGCTGAAGGTCGAACTCAAGGCCGTTAAAACCGAGCCGCGCGCATCCAAAACCCTCGAGAACCTGCTGGCGG
CTGAACGTGCGCGCATTGAAAGCGTCATCACCCGCGGTACCCGTGTGGTGGCGCTCGATGAACGCGGCACCGCGGTGACC
ACCGTGGCGCTGGCCGAAAAACTCAAGGCATGGCAGTTGTCGGGTGATGACGTGGCCATCGTGATCGGCGGGCCGGACGG
GCTGGACCCGGCCTTCAAGCAATCGGCGCACGAACGCCTGCGCCTGTCGGACCTGACCCTGCCGCATGCGATGGTGCGGG
TGTTGCTGATCGAGCAGCTTTACCGGGCCTGGAGCATCACCATCAACCATCCCTATCACCGCGAATAG

Upstream 100 bases:

>100_bases
GGGCACCGGCCAAGAAGGCTGCCACCAAGACCGCGGCCAGGACTACAGCCAAGACTGCAGCCGGGAAGCCGGCCGCCAGG
AAATCTGTCCCCCGGAGCAA

Downstream 100 bases:

>100_bases
CATGGTGTTCATGCTTGGCGCCGTGTCTGTTTTTTTATGGGTCAACCGCGGGCAACCGGGTAGCCATGTGAGTAGCCGTG
TGAGTAATGTGAGTAGCCAT

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIESVITRGTRVVALDERGTAVT
TVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERLRLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE

Sequences:

>Translated_155_residues
MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIESVITRGTRVVALDERGTAVT
TVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERLRLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE
>Mature_155_residues
MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIESVITRGTRVVALDERGTAVT
TVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERLRLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

Organism=Escherichia coli, GI1786855, Length=156, Percent_Identity=46.1538461538462, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 17335; Mature: 17335

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIE
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SVITRGTRVVALDERGTAVTTVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERL
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHHHHH
RLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE
HHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure
MRLTIVAVGQKVPDWAQTAYDDYAKRFPPELKVELKAVKTEPRASKTLENLLAAERARIE
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SVITRGTRVVALDERGTAVTTVALAEKLKAWQLSGDDVAIVIGGPDGLDPAFKQSAHERL
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHHHHH
RLSDLTLPHAMVRVLLIEQLYRAWSITINHPYHRE
HHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA