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The map label for this gene is fppS [H]

Identifier: 91787628

GI number: 91787628

Start: 1805574

End: 1806494

Strand: Direct

Name: fppS [H]

Synonym: Bpro_1746

Alternate gene names: 91787628

Gene position: 1805574-1806494 (Clockwise)

Preceding gene: 91787627

Following gene: 91787629

Centisome position: 34.72

GC content: 66.78

Gene sequence:

>921_bases
TTGAACGCCCCTGAAAAACTGCCTTTGTTCACGTTGAGCGCCTGGAGCGCCCAGCAGCTTGAGACTATCGAGCAGGCCTT
GTCCCGTTGGGTCGCTTGCCCGACCGATGCGCCCGCACCCGCGGGCCTGGGCGATGCCATGCGTTATGCCGTGCTCGACG
GCGGCAAGCGCCTGCGCCCGCTGCTGGTGATGGCGGCCTGCGAAGCCGTGAACGGCAACGCAGAGGCCGCGCTGCGCTCG
GCCTGCGCGGTGGAGCTGATTCACGCGTACTCGCTGGTGCATGATGACATGCCGTGCATGGACAACGACGTGCTGCGCCG
TGGCAAACCGACGGTGCACGTCAAGTTCGGCGAGGCGCAGGCGCTGCTTGCGGGTGACGCCCTGCAAGCCCTGGCCTTTG
AATTCCTCACACCCGACGATGGCTCGGTGGATGCCGCCACGCAGGCACGCCTGTGCCGCATGCTGGCGCAGGCCGCGGGC
TTTCAGGGCATGGCCGGCGGCCAGGCGATAGACCTGGCCAGTGTGGGCCTGCCCCTGACGTCCGGGCAACTGCATGAAAT
GCACCGCCTCAAAACCGGCGCATTGCTGCAGGCCAGCGTGATGATGGGCACGGCCTGCGGCGCCGCGCCGCCGGCCGCCC
AGCACGCCCTGCGCGAGTACGGCGCGGCGGTCGGCCTCGCATTCCAGGTGGTGGATGACATCCTGGATGTCACCGCGGAT
TCGGCCACGCTGGGTAAAACAGCCGGCAAGGACGCGGCCCAGGACAAGCCCACGTTTGTATCGCTGATGGGACTGCAAGC
ATCCAAAGACTACGCGCAGCAACTGCTGGGCAAGGCACTGGCCAGTCTTGACGCCAGCGGGCTTGGCAACACCCATGCCT
TGCATGCGTTGGCCGACATGCTGGTCAATCGCCACCACTAG

Upstream 100 bases:

>100_bases
TGGGTGCAAGAGTAGGGTAAGGACAAGAGTAAGCGTAATTCGCAGGGTCATCCCTGAATACAAGTCATCAGATACAGATA
CAAGTCATAGAGACCATAGC

Downstream 100 bases:

>100_bases
GAGCCGGGGACCGGCCTCGCCATAACAGACACACCACGATGTACCCATTGCTCGAAACCATCAACAGCCCCGCAGACCTG
CGCAGGCTGCCCCGCGCCCA

Product: farnesyl-diphosphate synthase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNAPEKLPLFTLSAWSAQQLETIEQALSRWVACPTDAPAPAGLGDAMRYAVLDGGKRLRPLLVMAACEAVNGNAEAALRS
ACAVELIHAYSLVHDDMPCMDNDVLRRGKPTVHVKFGEAQALLAGDALQALAFEFLTPDDGSVDAATQARLCRMLAQAAG
FQGMAGGQAIDLASVGLPLTSGQLHEMHRLKTGALLQASVMMGTACGAAPPAAQHALREYGAAVGLAFQVVDDILDVTAD
SATLGKTAGKDAAQDKPTFVSLMGLQASKDYAQQLLGKALASLDASGLGNTHALHALADMLVNRHH

Sequences:

>Translated_306_residues
MNAPEKLPLFTLSAWSAQQLETIEQALSRWVACPTDAPAPAGLGDAMRYAVLDGGKRLRPLLVMAACEAVNGNAEAALRS
ACAVELIHAYSLVHDDMPCMDNDVLRRGKPTVHVKFGEAQALLAGDALQALAFEFLTPDDGSVDAATQARLCRMLAQAAG
FQGMAGGQAIDLASVGLPLTSGQLHEMHRLKTGALLQASVMMGTACGAAPPAAQHALREYGAAVGLAFQVVDDILDVTAD
SATLGKTAGKDAAQDKPTFVSLMGLQASKDYAQQLLGKALASLDASGLGNTHALHALADMLVNRHH
>Mature_306_residues
MNAPEKLPLFTLSAWSAQQLETIEQALSRWVACPTDAPAPAGLGDAMRYAVLDGGKRLRPLLVMAACEAVNGNAEAALRS
ACAVELIHAYSLVHDDMPCMDNDVLRRGKPTVHVKFGEAQALLAGDALQALAFEFLTPDDGSVDAATQARLCRMLAQAAG
FQGMAGGQAIDLASVGLPLTSGQLHEMHRLKTGALLQASVMMGTACGAAPPAAQHALREYGAAVGLAFQVVDDILDVTAD
SATLGKTAGKDAAQDKPTFVSLMGLQASKDYAQQLLGKALASLDASGLGNTHALHALADMLVNRHH

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786623, Length=296, Percent_Identity=45.6081081081081, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789578, Length=212, Percent_Identity=33.0188679245283, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24651612, Length=219, Percent_Identity=28.310502283105, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 31858; Mature: 31858

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPEKLPLFTLSAWSAQQLETIEQALSRWVACPTDAPAPAGLGDAMRYAVLDGGKRLRP
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
LLVMAACEAVNGNAEAALRSACAVELIHAYSLVHDDMPCMDNDVLRRGKPTVHVKFGEAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCH
ALLAGDALQALAFEFLTPDDGSVDAATQARLCRMLAQAAGFQGMAGGQAIDLASVGLPLT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCCC
SGQLHEMHRLKTGALLQASVMMGTACGAAPPAAQHALREYGAAVGLAFQVVDDILDVTAD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SATLGKTAGKDAAQDKPTFVSLMGLQASKDYAQQLLGKALASLDASGLGNTHALHALADM
CHHHCCCCCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVNRHH
HHHCCC
>Mature Secondary Structure
MNAPEKLPLFTLSAWSAQQLETIEQALSRWVACPTDAPAPAGLGDAMRYAVLDGGKRLRP
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
LLVMAACEAVNGNAEAALRSACAVELIHAYSLVHDDMPCMDNDVLRRGKPTVHVKFGEAQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCH
ALLAGDALQALAFEFLTPDDGSVDAATQARLCRMLAQAAGFQGMAGGQAIDLASVGLPLT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCCC
SGQLHEMHRLKTGALLQASVMMGTACGAAPPAAQHALREYGAAVGLAFQVVDDILDVTAD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SATLGKTAGKDAAQDKPTFVSLMGLQASKDYAQQLLGKALASLDASGLGNTHALHALADM
CHHHCCCCCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVNRHH
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]