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The map label for this gene is boxD [H]

Identifier: 91787507

GI number: 91787507

Start: 1677436

End: 1678992

Strand: Reverse

Name: boxD [H]

Synonym: Bpro_1625

Alternate gene names: 91787507

Gene position: 1678992-1677436 (Counterclockwise)

Preceding gene: 91787508

Following gene: 91787506

Centisome position: 32.29

GC content: 68.21

Gene sequence:

>1557_bases
ATGACTGAACTGATTTCCAACTTCCTCGGCGGCCGCTGGCAGGCCGGTAGCGGCGCCGGCACGCCCCTGTTCGACCCCAC
CCTCGGCACCGAGCTGGTCCGCGTGGACGCCACCGGGCTTGATCTCGCGGCAGGCTTTGCGTTTGCACGCGAGCAGGGCC
GCGCAGCGCTGCAGCGCCTGACCTACCGCGAGCGCGCCGCGATGCTGGCCGCCGCCGTCAAGGTGCTGCAGGCGAACCGC
GATGCCTACTATGACATCGCCACGGCCAACAGCGGCACCGTCAAGAACGACTCGACGGTGGACATCGACGGCGGCATCTT
CACGCTCGGCAACTACGCAAAACTCGGCGACTCACTGGGCGACCGCCGCTTTCTGCTCGACGGCGAGATGACTCGGCTGG
GCAAGGAAGACCTGTTCCAGTCGCAACATGTGCTGACGCCCACGCGGGGCATCGCCCTGTTCATCAACGCCTTCAACTTT
CCGAGCTGGGGCCTGTGGGAAAAGGCGGCGCCCGCGCTGCTGTCCGGCGTGCCGGTGATCGTCAAGCCCGCCACCACCAC
AGCCTGGCTCACCCAGCGCATGGTGCAGGACGTGGTCGAGGCCGGCATCTTCCCGGCCGGCGCACTGTCGGTCGTGTGCG
GCAGCTCTGCGGGCCTGATGGACGCGCTGCAACCTTTTGACGTCGTGTCGTTCACCGGATCGGCAGAAACAGCAGCCGTG
ATCCGCTCGCATCCCGCCGTGACGCAACGCTCGGTGCGCGTCAACATCGAAGCGGACAGCCTCAACTCGGCCCTGCTGCT
GCCCGGTGAAGCCGCTGGCAGCGCCGCCTTCGATTTGCTGGTCAAGGAAGTGGTGCGCGAGATGACGGTCAAATCAGGCC
AGAAATGCACCGCGATTCGCCGCGTCTTCGTCCCCGAGGACCTGTATGGCCCGGTGGCCGAGGCGATCGCCGCGCGCCTG
TCCAAAACCGTTGTCGGCAACCCGCGCAATGAAACCGTTCGCATGGGCGCGCTGGTTAACCGCGCGCAGCTGGCCAGCGT
CCGCGAGGGCCTGGCCCACCTGCAAACCCAAGCCGAGCTGCTGCACGATGGCAGCACGCACGCGCTGGTCGATGCCGACC
CCGCCGTGGCTTGCTGTGTCGGGCCCACGCTGTTGGGCGCCCGCGATGCCGACGCGGCGGACCGCATCCACGACACCGAA
GTGTTTGGCCCGGTGGCCACCCTGATGCCTTATCGCCATGCCGCCAGCGACATGGCTCACGCGCTCACTCTGGTGCGTCG
CGGCCACGGCTCGCTGGTGGCCTCGCTCTATGGCAGCGACCCGGCCGCGCTGGCCGCCACCGCGCTGGAGCTGGCCGACA
GCCACGGCCGCGTGCATGTGATCTCGCCCGATGTGGCGCAACTGCACACCGGCCATGGCAATGTGATGCCGCAGTCGCTC
CACGGTGGCCCCGGGCGCGCGGGCGGCGGAGAGGAACTCGGTGGCGTGCGTGCCCTGAACTTCTACCACCGCCGCAGCGC
GGTGCAAGCCAGCACCGCCGTGCTCAAAACCCTCTAA

Upstream 100 bases:

>100_bases
TGCGCAGGCAGGTTCGGAGCCGCAGGCTCCAGCCCCTTGGGGGCTAATTTCCCTTGGGGCGGCCCGGCGGCGTCACGATT
ACTCCTCACGAAAGAATTGC

Downstream 100 bases:

>100_bases
GCACCGCCGACTGCCCTGCAAAAATCAAGGAGACAGACTTGACCCCCACCCTCCCCGTCGCGCCGCCCGGCGCGCGCTTT
AACTTTGCCCACCACCTGAT

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MTELISNFLGGRWQAGSGAGTPLFDPTLGTELVRVDATGLDLAAGFAFAREQGRAALQRLTYRERAAMLAAAVKVLQANR
DAYYDIATANSGTVKNDSTVDIDGGIFTLGNYAKLGDSLGDRRFLLDGEMTRLGKEDLFQSQHVLTPTRGIALFINAFNF
PSWGLWEKAAPALLSGVPVIVKPATTTAWLTQRMVQDVVEAGIFPAGALSVVCGSSAGLMDALQPFDVVSFTGSAETAAV
IRSHPAVTQRSVRVNIEADSLNSALLLPGEAAGSAAFDLLVKEVVREMTVKSGQKCTAIRRVFVPEDLYGPVAEAIAARL
SKTVVGNPRNETVRMGALVNRAQLASVREGLAHLQTQAELLHDGSTHALVDADPAVACCVGPTLLGARDADAADRIHDTE
VFGPVATLMPYRHAASDMAHALTLVRRGHGSLVASLYGSDPAALAATALELADSHGRVHVISPDVAQLHTGHGNVMPQSL
HGGPGRAGGGEELGGVRALNFYHRRSAVQASTAVLKTL

Sequences:

>Translated_518_residues
MTELISNFLGGRWQAGSGAGTPLFDPTLGTELVRVDATGLDLAAGFAFAREQGRAALQRLTYRERAAMLAAAVKVLQANR
DAYYDIATANSGTVKNDSTVDIDGGIFTLGNYAKLGDSLGDRRFLLDGEMTRLGKEDLFQSQHVLTPTRGIALFINAFNF
PSWGLWEKAAPALLSGVPVIVKPATTTAWLTQRMVQDVVEAGIFPAGALSVVCGSSAGLMDALQPFDVVSFTGSAETAAV
IRSHPAVTQRSVRVNIEADSLNSALLLPGEAAGSAAFDLLVKEVVREMTVKSGQKCTAIRRVFVPEDLYGPVAEAIAARL
SKTVVGNPRNETVRMGALVNRAQLASVREGLAHLQTQAELLHDGSTHALVDADPAVACCVGPTLLGARDADAADRIHDTE
VFGPVATLMPYRHAASDMAHALTLVRRGHGSLVASLYGSDPAALAATALELADSHGRVHVISPDVAQLHTGHGNVMPQSL
HGGPGRAGGGEELGGVRALNFYHRRSAVQASTAVLKTL
>Mature_517_residues
TELISNFLGGRWQAGSGAGTPLFDPTLGTELVRVDATGLDLAAGFAFAREQGRAALQRLTYRERAAMLAAAVKVLQANRD
AYYDIATANSGTVKNDSTVDIDGGIFTLGNYAKLGDSLGDRRFLLDGEMTRLGKEDLFQSQHVLTPTRGIALFINAFNFP
SWGLWEKAAPALLSGVPVIVKPATTTAWLTQRMVQDVVEAGIFPAGALSVVCGSSAGLMDALQPFDVVSFTGSAETAAVI
RSHPAVTQRSVRVNIEADSLNSALLLPGEAAGSAAFDLLVKEVVREMTVKSGQKCTAIRRVFVPEDLYGPVAEAIAARLS
KTVVGNPRNETVRMGALVNRAQLASVREGLAHLQTQAELLHDGSTHALVDADPAVACCVGPTLLGARDADAADRIHDTEV
FGPVATLMPYRHAASDMAHALTLVRRGHGSLVASLYGSDPAALAATALELADSHGRVHVISPDVAQLHTGHGNVMPQSLH
GGPGRAGGGEELGGVRALNFYHRRSAVQASTAVLKTL

Specific function: Catalyzes the NADP-dependent oxidation of 3,4- dehydroadipyl-CoA semialdehyde to form cis-3,4-dehydroadipyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=508, Percent_Identity=24.8031496062992, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI25777724, Length=495, Percent_Identity=24.040404040404, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI25777732, Length=509, Percent_Identity=26.1296660117878, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI153266822, Length=502, Percent_Identity=22.9083665338645, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI115387104, Length=522, Percent_Identity=25.4789272030651, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI12007648, Length=418, Percent_Identity=24.8803827751196, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25777730, Length=499, Percent_Identity=25.250501002004, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI25777728, Length=435, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4507229, Length=455, Percent_Identity=24.8351648351648, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1787653, Length=515, Percent_Identity=44.8543689320388, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1789015, Length=419, Percent_Identity=24.3436754176611, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786504, Length=530, Percent_Identity=24.7169811320755, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082295, Length=446, Percent_Identity=23.7668161434978, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787715, Length=501, Percent_Identity=21.9560878243513, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081896, Length=352, Percent_Identity=29.2613636363636, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787684, Length=323, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787558, Length=447, Percent_Identity=23.489932885906, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551164, Length=466, Percent_Identity=22.5321888412017, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=365, Percent_Identity=25.2054794520548, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115532534, Length=365, Percent_Identity=25.2054794520548, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562198, Length=508, Percent_Identity=23.0314960629921, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32564151, Length=287, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=25.1655629139073, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=365, Percent_Identity=26.5753424657534, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325196, Length=429, Percent_Identity=24.7086247086247, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=423, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650465, Length=490, Percent_Identity=25.7142857142857, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129399, Length=423, Percent_Identity=26.7139479905437, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668425, Length=366, Percent_Identity=24.3169398907104, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24668417, Length=366, Percent_Identity=24.3169398907104, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24668413, Length=366, Percent_Identity=24.3169398907104, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281362580, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI62472918, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI62472926, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI62472936, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356737, Length=399, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.77 [H]

Molecular weight: Translated: 54432; Mature: 54301

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELISNFLGGRWQAGSGAGTPLFDPTLGTELVRVDATGLDLAAGFAFAREQGRAALQRL
CHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
TYRERAAMLAAAVKVLQANRDAYYDIATANSGTVKNDSTVDIDGGIFTLGNYAKLGDSLG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCEEECCCHHHHCCCCC
DRRFLLDGEMTRLGKEDLFQSQHVLTPTRGIALFINAFNFPSWGLWEKAAPALLSGVPVI
CCEEEECCHHHHCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEE
VKPATTTAWLTQRMVQDVVEAGIFPAGALSVVCGSSAGLMDALQPFDVVSFTGSAETAAV
EECCCHHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCHHHHCCCCCEEEECCCCHHHHH
IRSHPAVTQRSVRVNIEADSLNSALLLPGEAAGSAAFDLLVKEVVREMTVKSGQKCTAIR
HHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
RVFVPEDLYGPVAEAIAARLSKTVVGNPRNETVRMGALVNRAQLASVREGLAHLQTQAEL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LHDGSTHALVDADPAVACCVGPTLLGARDADAADRIHDTEVFGPVATLMPYRHAASDMAH
HHCCCCCEEEECCCCEEEECCCHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALTLVRRGHGSLVASLYGSDPAALAATALELADSHGRVHVISPDVAQLHTGHGNVMPQSL
HHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCC
HGGPGRAGGGEELGGVRALNFYHRRSAVQASTAVLKTL
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TELISNFLGGRWQAGSGAGTPLFDPTLGTELVRVDATGLDLAAGFAFAREQGRAALQRL
HHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
TYRERAAMLAAAVKVLQANRDAYYDIATANSGTVKNDSTVDIDGGIFTLGNYAKLGDSLG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCEEECCCHHHHCCCCC
DRRFLLDGEMTRLGKEDLFQSQHVLTPTRGIALFINAFNFPSWGLWEKAAPALLSGVPVI
CCEEEECCHHHHCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEE
VKPATTTAWLTQRMVQDVVEAGIFPAGALSVVCGSSAGLMDALQPFDVVSFTGSAETAAV
EECCCHHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCHHHHCCCCCEEEECCCCHHHHH
IRSHPAVTQRSVRVNIEADSLNSALLLPGEAAGSAAFDLLVKEVVREMTVKSGQKCTAIR
HHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
RVFVPEDLYGPVAEAIAARLSKTVVGNPRNETVRMGALVNRAQLASVREGLAHLQTQAEL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LHDGSTHALVDADPAVACCVGPTLLGARDADAADRIHDTEVFGPVATLMPYRHAASDMAH
HHCCCCCEEEECCCCEEEECCCHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALTLVRRGHGSLVASLYGSDPAALAATALELADSHGRVHVISPDVAQLHTGHGNVMPQSL
HHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCC
HGGPGRAGGGEELGGVRALNFYHRRSAVQASTAVLKTL
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12399500 [H]