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The map label for this gene is pcp [H]

Identifier: 91787406

GI number: 91787406

Start: 1568288

End: 1568932

Strand: Reverse

Name: pcp [H]

Synonym: Bpro_1512

Alternate gene names: 91787406

Gene position: 1568932-1568288 (Counterclockwise)

Preceding gene: 91787408

Following gene: 91787402

Centisome position: 30.17

GC content: 65.74

Gene sequence:

>645_bases
GTGCTGCTCACCGGTTTTGATGCGTTTGGCGAAGCCAGGCTGGCTGGCCCCGCACTCAACCCCAGCTGGCTGGCCGTCCA
GGCACTGCACGCCACACGCATCGCGGGTCACGAGGTGATTGCGGCACAGTTGCCGACCCGGTTCGACACATCGGTGACGG
AACTCATGCGCCTGTTGCGTCTTTACCGGCCAGCGCTTGTGATTTGCGTCGGGCAGGCAGGCGGGCGAAACGCCTTGTCG
CTGGAAAGGATCGCCATCAACGTCAACGATGCCCGCATCCCCGACAACGCGGGCATGCAACCCGTCGACACGCCCGTCGT
GGCAGGAGGCCCGACGGCCTACTTCAGCACGCTGCCCATCAAGGCCATGCTGCAGGCTCTGCAGGACGCCGGGCTGGCCG
CCGAGGTGTCGCAGACAGCGGGCACCTTTGTCTGCAACCACGCGTTTTATGCACTGATGCACGCGCTGGCCACGCAGCGC
GGCTTCAGGCGCACGCGCGGTGGCTTCGTCCATGTGCCTTACCTGCCGGAACAAGGCGCGCCCAGCCTGCCGCTGGAAGA
CATGGTGCACGGGCTGCAAGTGGCGATAGCCGCTGCGCTGGCAACGCCGAACGACATCACAAAAAGCGCGGGCGCAGTCA
GCTAG

Upstream 100 bases:

>100_bases
ACCCACCGCGCAACGGGGAGCGCCATTTCGCAGACCACAGCGATACACCCCAGCCATACTTCACAATGGCAACATGGACA
CAGCCTCCACCCCTCCCCGC

Downstream 100 bases:

>100_bases
GTCGGCGGCGTCGGGCTGCCCCGCTGCTCCGGCGCATCGGCGGCGGGGTCATTGCGCATCAGCCGCCAGGCCAGCCAGAT
GCCGATGGCCGCATTGCCGA

Product: pyroglutamyl-peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MLLTGFDAFGEARLAGPALNPSWLAVQALHATRIAGHEVIAAQLPTRFDTSVTELMRLLRLYRPALVICVGQAGGRNALS
LERIAINVNDARIPDNAGMQPVDTPVVAGGPTAYFSTLPIKAMLQALQDAGLAAEVSQTAGTFVCNHAFYALMHALATQR
GFRRTRGGFVHVPYLPEQGAPSLPLEDMVHGLQVAIAAALATPNDITKSAGAVS

Sequences:

>Translated_214_residues
MLLTGFDAFGEARLAGPALNPSWLAVQALHATRIAGHEVIAAQLPTRFDTSVTELMRLLRLYRPALVICVGQAGGRNALS
LERIAINVNDARIPDNAGMQPVDTPVVAGGPTAYFSTLPIKAMLQALQDAGLAAEVSQTAGTFVCNHAFYALMHALATQR
GFRRTRGGFVHVPYLPEQGAPSLPLEDMVHGLQVAIAAALATPNDITKSAGAVS
>Mature_214_residues
MLLTGFDAFGEARLAGPALNPSWLAVQALHATRIAGHEVIAAQLPTRFDTSVTELMRLLRLYRPALVICVGQAGGRNALS
LERIAINVNDARIPDNAGMQPVDTPVVAGGPTAYFSTLPIKAMLQALQDAGLAAEVSQTAGTFVCNHAFYALMHALATQR
GFRRTRGGFVHVPYLPEQGAPSLPLEDMVHGLQVAIAAALATPNDITKSAGAVS

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 22533; Mature: 22533

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTGFDAFGEARLAGPALNPSWLAVQALHATRIAGHEVIAAQLPTRFDTSVTELMRLLR
CEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHH
LYRPALVICVGQAGGRNALSLERIAINVNDARIPDNAGMQPVDTPVVAGGPTAYFSTLPI
HHCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCH
KAMLQALQDAGLAAEVSQTAGTFVCNHAFYALMHALATQRGFRRTRGGFVHVPYLPEQGA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
PSLPLEDMVHGLQVAIAAALATPNDITKSAGAVS
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MLLTGFDAFGEARLAGPALNPSWLAVQALHATRIAGHEVIAAQLPTRFDTSVTELMRLLR
CEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHH
LYRPALVICVGQAGGRNALSLERIAINVNDARIPDNAGMQPVDTPVVAGGPTAYFSTLPI
HHCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCH
KAMLQALQDAGLAAEVSQTAGTFVCNHAFYALMHALATQRGFRRTRGGFVHVPYLPEQGA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
PSLPLEDMVHGLQVAIAAALATPNDITKSAGAVS
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA