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The map label for this gene is ykgC [H]

Identifier: 91787403

GI number: 91787403

Start: 1565924

End: 1567309

Strand: Direct

Name: ykgC [H]

Synonym: Bpro_1509

Alternate gene names: 91787403

Gene position: 1565924-1567309 (Clockwise)

Preceding gene: 91787401

Following gene: 91787404

Centisome position: 30.11

GC content: 63.92

Gene sequence:

>1386_bases
ATGCAAGTCGAATCTTTTGATGCCATCGTCATAGGCGCCGGGCAAGCAGGGCCTGCGTTGGCTGAGCGTTGCACCAAAGA
AGGCCTGCGCACGGCAGTGATTGAGCGTGCCCATTTCGGCGGCACCTGCGTCAACGTCGGCTGCATACCCACCAAGACGC
TGGTGGCCAGCGCGCGGGCGATCCACATGGCCAGGCGCGGCGCTGAATTCGGATTTTCCGCCGGCGATATCCAGGTCAAC
ATGCAGCGGGTCAAGACGCGAAAGGACGAGATCGTTCTCAAATCGCGCAACGGTATCCATCAGTGGATGCAGGGCCTGAA
AAATGCCGAGGTGATTCAGGGCGATGCCGCATTCGTGGGGCCGCGCACTGTCAAGGTCGGCGAGCGCACGCTGACGGCCC
CGCGGATATTCCTCAATGTGGGCGGCCGGCCTTCCGTCCCGGAGCTGGCGGGTGTCCATGATGTCCCCTATCTGGACAAC
GCGTCCATCATGGAGCTGACCGAGGTGCCGGAACACCTGGTGATTGTTGGTGGCAGCTATATCGGCCTCGAATTTGCGCA
AATGATGCGGCGCTTTGGCGCCAGGGTCACCGTGGTGGAGCGCTCGGCCAAATTGCTGTCCCGCGAGGACGAGGATGTGT
CGGATGGCATTCGCGCCATCCTGGAGGCAGAGGGCGTCGGGTTCCAGCTGGAGGCGGAGTGCCTGTCGCTGGCGCGGGAG
GGGAGCGGGATTTTGGTCGGCACCGTGTGTGCCACGGAGTCGCCCGCCCTCATTGCCAGCCATGTACTTCTGGCCGTCGG
CAGGCGTCCTAATACAGACGGCATGGGGCTGGACGTCGCGGGCATCGAGCTCGATGAGCGCGGCTACATCATCGTTGACG
ATCAGCTTCGCACCAGTGCCGAAGGGGTGTGGGCCATGGGTGATTGCAATGGCCGGGGCGCGTTTACCCACACGTCCTGG
AATGACTACGAGATCGTCGCCGCCAACCTGTTTGATGGCGACCCGCGCCGCGTGAGCGACCGGATACCGTGCTATGCGCT
CTTCATTGACCCCGCGCTTGGTCGTGTGGGCCTGACCGAGCGCGAAGTGCGCGCCAGCGGGCGTGCGGCGCTGGTGGCGC
GCATGCCCATGCAGCGCGTAGGCCGTGCCCGCGAAGCCGGCGAGACGCAGGGGTTCATGAAGGCCCTCGTCGACGCAGAC
ACGAAGCGCCTGCTGGGCGCCGCCATCCTGGGCCTCAACGGCGACGAAGTGGTTCACGCACTGGTCGACATCATGGCCGC
CGACCAGCCTTACACGGCCATCAGCCGTGCGATGCACATCCATCCCACCGTCAGCGAATTGATTCCAACATTGCTGCAGC
AGCTGAAGCCGCTGGAAGCGCAATAA

Upstream 100 bases:

>100_bases
GGATATGGTTGGTTGGTCATGAACCTGCCATAGGGCACGTCATCGCCCCGTGTGCTTGTGTCCTTGTGTCCTTGTGTACC
CACGGAAACCGGAGAAGCTC

Downstream 100 bases:

>100_bases
AGCAATAAAGCAATAAAGTAATAGAGGGGTGTTTCACCTGCACCCGCAGGTGCTGCAAACAAAGCTGCTTGCGCCGGCAT
GGCGCGAATGCCGCCTCGCC

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQVESFDAIVIGAGQAGPALAERCTKEGLRTAVIERAHFGGTCVNVGCIPTKTLVASARAIHMARRGAEFGFSAGDIQVN
MQRVKTRKDEIVLKSRNGIHQWMQGLKNAEVIQGDAAFVGPRTVKVGERTLTAPRIFLNVGGRPSVPELAGVHDVPYLDN
ASIMELTEVPEHLVIVGGSYIGLEFAQMMRRFGARVTVVERSAKLLSREDEDVSDGIRAILEAEGVGFQLEAECLSLARE
GSGILVGTVCATESPALIASHVLLAVGRRPNTDGMGLDVAGIELDERGYIIVDDQLRTSAEGVWAMGDCNGRGAFTHTSW
NDYEIVAANLFDGDPRRVSDRIPCYALFIDPALGRVGLTEREVRASGRAALVARMPMQRVGRAREAGETQGFMKALVDAD
TKRLLGAAILGLNGDEVVHALVDIMAADQPYTAISRAMHIHPTVSELIPTLLQQLKPLEAQ

Sequences:

>Translated_461_residues
MQVESFDAIVIGAGQAGPALAERCTKEGLRTAVIERAHFGGTCVNVGCIPTKTLVASARAIHMARRGAEFGFSAGDIQVN
MQRVKTRKDEIVLKSRNGIHQWMQGLKNAEVIQGDAAFVGPRTVKVGERTLTAPRIFLNVGGRPSVPELAGVHDVPYLDN
ASIMELTEVPEHLVIVGGSYIGLEFAQMMRRFGARVTVVERSAKLLSREDEDVSDGIRAILEAEGVGFQLEAECLSLARE
GSGILVGTVCATESPALIASHVLLAVGRRPNTDGMGLDVAGIELDERGYIIVDDQLRTSAEGVWAMGDCNGRGAFTHTSW
NDYEIVAANLFDGDPRRVSDRIPCYALFIDPALGRVGLTEREVRASGRAALVARMPMQRVGRAREAGETQGFMKALVDAD
TKRLLGAAILGLNGDEVVHALVDIMAADQPYTAISRAMHIHPTVSELIPTLLQQLKPLEAQ
>Mature_461_residues
MQVESFDAIVIGAGQAGPALAERCTKEGLRTAVIERAHFGGTCVNVGCIPTKTLVASARAIHMARRGAEFGFSAGDIQVN
MQRVKTRKDEIVLKSRNGIHQWMQGLKNAEVIQGDAAFVGPRTVKVGERTLTAPRIFLNVGGRPSVPELAGVHDVPYLDN
ASIMELTEVPEHLVIVGGSYIGLEFAQMMRRFGARVTVVERSAKLLSREDEDVSDGIRAILEAEGVGFQLEAECLSLARE
GSGILVGTVCATESPALIASHVLLAVGRRPNTDGMGLDVAGIELDERGYIIVDDQLRTSAEGVWAMGDCNGRGAFTHTSW
NDYEIVAANLFDGDPRRVSDRIPCYALFIDPALGRVGLTEREVRASGRAALVARMPMQRVGRAREAGETQGFMKALVDAD
TKRLLGAAILGLNGDEVVHALVDIMAADQPYTAISRAMHIHPTVSELIPTLLQQLKPLEAQ

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI50301238, Length=465, Percent_Identity=30.1075268817204, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI91199540, Length=453, Percent_Identity=26.9315673289183, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI148277065, Length=445, Percent_Identity=25.3932584269663, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI33519430, Length=445, Percent_Identity=25.3932584269663, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI33519428, Length=445, Percent_Identity=25.3932584269663, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI33519426, Length=445, Percent_Identity=25.3932584269663, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI148277071, Length=445, Percent_Identity=25.3932584269663, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI291045266, Length=433, Percent_Identity=25.635103926097, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI22035672, Length=461, Percent_Identity=26.8980477223427, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI291045268, Length=428, Percent_Identity=24.7663551401869, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87081717, Length=463, Percent_Identity=36.0691144708423, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1786307, Length=451, Percent_Identity=31.0421286031042, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789915, Length=438, Percent_Identity=27.8538812785388, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87082354, Length=421, Percent_Identity=27.3159144893112, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32565766, Length=453, Percent_Identity=29.1390728476821, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71983429, Length=463, Percent_Identity=27.645788336933, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71983419, Length=463, Percent_Identity=27.645788336933, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17557007, Length=479, Percent_Identity=26.7223382045929, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71982272, Length=488, Percent_Identity=25, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559934, Length=288, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321091, Length=464, Percent_Identity=27.801724137931, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6325240, Length=483, Percent_Identity=25.879917184265, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325166, Length=471, Percent_Identity=22.9299363057325, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21358499, Length=451, Percent_Identity=28.6031042128603, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24640549, Length=478, Percent_Identity=26.3598326359833, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24640553, Length=478, Percent_Identity=26.3598326359833, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24640551, Length=478, Percent_Identity=26.3598326359833, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17737741, Length=465, Percent_Identity=23.8709677419355, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 49594; Mature: 49594

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVESFDAIVIGAGQAGPALAERCTKEGLRTAVIERAHFGGTCVNVGCIPTKTLVASARA
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
IHMARRGAEFGFSAGDIQVNMQRVKTRKDEIVLKSRNGIHQWMQGLKNAEVIQGDAAFVG
HHHHHCCCCCCCCCCCEEEEHHHHHCCCCCEEEECCCCHHHHHHHCCCCEEEECCCEEEC
PRTVKVGERTLTAPRIFLNVGGRPSVPELAGVHDVPYLDNASIMELTEVPEHLVIVGGSY
CEEEEECCCEECCCEEEEECCCCCCCCHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCCH
IGLEFAQMMRRFGARVTVVERSAKLLSREDEDVSDGIRAILEAEGVGFQLEAECLSLARE
HHHHHHHHHHHHCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHC
GSGILVGTVCATESPALIASHVLLAVGRRPNTDGMGLDVAGIELDERGYIIVDDQLRTSA
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCC
EGVWAMGDCNGRGAFTHTSWNDYEIVAANLFDGDPRRVSDRIPCYALFIDPALGRVGLTE
CCEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCCCH
REVRASGRAALVARMPMQRVGRAREAGETQGFMKALVDADTKRLLGAAILGLNGDEVVHA
HHHHCCCCEEEEHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LVDIMAADQPYTAISRAMHIHPTVSELIPTLLQQLKPLEAQ
HHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQVESFDAIVIGAGQAGPALAERCTKEGLRTAVIERAHFGGTCVNVGCIPTKTLVASARA
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
IHMARRGAEFGFSAGDIQVNMQRVKTRKDEIVLKSRNGIHQWMQGLKNAEVIQGDAAFVG
HHHHHCCCCCCCCCCCEEEEHHHHHCCCCCEEEECCCCHHHHHHHCCCCEEEECCCEEEC
PRTVKVGERTLTAPRIFLNVGGRPSVPELAGVHDVPYLDNASIMELTEVPEHLVIVGGSY
CEEEEECCCEECCCEEEEECCCCCCCCHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCCH
IGLEFAQMMRRFGARVTVVERSAKLLSREDEDVSDGIRAILEAEGVGFQLEAECLSLARE
HHHHHHHHHHHHCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHC
GSGILVGTVCATESPALIASHVLLAVGRRPNTDGMGLDVAGIELDERGYIIVDDQLRTSA
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCC
EGVWAMGDCNGRGAFTHTSWNDYEIVAANLFDGDPRRVSDRIPCYALFIDPALGRVGLTE
CCEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCHHHHCCCCEEEEEECCCCCCCCCCH
REVRASGRAALVARMPMQRVGRAREAGETQGFMKALVDADTKRLLGAAILGLNGDEVVHA
HHHHCCCCEEEEHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LVDIMAADQPYTAISRAMHIHPTVSELIPTLLQQLKPLEAQ
HHHHHHCCCCHHHHHHHEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]