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The map label for this gene is hutH [H]

Identifier: 91787057

GI number: 91787057

Start: 1201552

End: 1203186

Strand: Reverse

Name: hutH [H]

Synonym: Bpro_1160

Alternate gene names: 91787057

Gene position: 1203186-1201552 (Counterclockwise)

Preceding gene: 91787058

Following gene: 91787055

Centisome position: 23.14

GC content: 66.79

Gene sequence:

>1635_bases
ATGAACATCCAGCCAGGCTTCTTAACCTTGACGCAACTGCGCCAGATCCACGCAGGCAGCGAGCCGCTGACGATAGATCC
GTCAGCCACCGCAGGCATTCGTGCCAGCGCCCAGCTCGTCCAGCAGGCCGCGCAGGGCGGCGCCGCCGTCTATGGCGTGA
ACACCGGTTTCGGCAAGCTGGCCAACCAGCGCATCGCCCAAACCGACTTGAATACCCTGCAGCTCAACCTGTTGCGCTCG
CATGCCGTCGGTGTGGGCGAGCCCATGCCGGAGCGGGTGGTACGGCTGGTCCTGCTGCTCAAGGCCGCCAGCCTGGCGCG
CGGCTTTTCGGGCGTGCGTGAATGTGTCATCGACCTGCTGCTGGCCCTGTACAACCACGGCTTGACGCCGGTGATTCCCT
GCCAGGGATCGGTCGGCGCCTCCGGCGACCTCGCGCCGCTGGCGCATTTGTGCCTCCCATTGATTGGCGAAGGCGAGGTG
TTTTATCGCGGCGAGCGCCTGCCCGCCGCAGCCGCGCTGCAACAGGCCCCCCTGGCCCCGATACAGTTGTCGGCCAAGGA
GGGGCTGGCCCTGATCAATGGCACGCAGGTCTCCACCGCACTGGCGCTTGATGCCCTGCTGGCGACCGAGCGCCTGTTCG
AAGCCGCCGTGATTTCCGGGGCGGTCACGCTCGACGCCGCACGCGGCAGCGACGGCCCGTTTGATCCCCGCATTCACGCC
GTGCGCGGCCAGCCCGGGCAGATCGCCTGTGCCGCTGCCTACCGCGCGCTGATGGTCGGCAGCGAGATCCGCCGCTCCCA
CCTGGAGGGCGACGACCGGGTGCAGGATCCGTACTGCCTGCGCTGCCAGCCGCAGGTCATGGGCGCCTGCCTGGATCAGA
TGCGCTATGCCTCGCAGGTGTTGATGCGTGAAGCCAATGCCGTCACCGACAACCCGCTGGTGTTCGCCTCCACCCAGGAA
GTTGCCGTGCAAGCGGGGGCCGTGGAACCGGCTTTGCCGGGCCACAGGAGCCGCCCCCTTGAGGGGGAGGTGGCCACAGG
CCACGTCGGGGGGGAGCTTTTGTCAGGCGGCAATTTTCATGCGGAACCGGTGGCGCTGGCTGCCGATGCGCTGGCCGTGG
TCATTGCGGAAATCGGCGCCATCACCGAGCGGCGCATTGCCATGCTGGTCGATACGGTGGTGTCTCGCCTGCCGGCCTTT
CTCACGCCCGAGCCCGGGCTGAATTCGGGTTTCATGATCGTGCACGTGACGGCCGCCGCGCTGGCGTCAGAAAACAAGTC
GCTGGCCCATCCGGCCAGTGTGGACAGCCTGCCCACCTCGGCCAACCAGGAAGACCACGTGAGCATGGCGACCTTTGCGG
CCCGCCGGCTTCAGCCCATGCTGCGCAACACGGAGTACATCGTGGCCATTGAACTGCTGACGGCGGCCCAGGGGATCGAA
TTTCTGCGGCCGCTGAAAAGCGCTTCTGTATTGGAAGGTGTGCTGCAACTGGTGCGTTCGGTATCGCCAGCCATGATGCG
CGACCGCAGCCTGGCGCCTGACATCGGTGCGGTGCATCAATTGGTGGCGCAGGGGCGTATCGGCCTGGCGGGGGAGGCGC
AAATTACCGAGCTGACCGCCTTGCGGCTGGTGTAA

Upstream 100 bases:

>100_bases
GCGCTGGGCTGAAGTGATCCGGCAAAAGAACATCAAACCCGAATGAGGTAATACCGTAATACCCACGCTTCCCGCTGTCA
CTGCTTGCCAACGAGTCACC

Downstream 100 bases:

>100_bases
AGCCGCGGACCTCATCCGGCAGGCAGCCCCGCAGCTACAGGCCCAGCCGCAGCGTCACAATGGCGGCCAGAACCAGCGAG
GCGATGAAAACCGTCTCGCC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MNIQPGFLTLTQLRQIHAGSEPLTIDPSATAGIRASAQLVQQAAQGGAAVYGVNTGFGKLANQRIAQTDLNTLQLNLLRS
HAVGVGEPMPERVVRLVLLLKAASLARGFSGVRECVIDLLLALYNHGLTPVIPCQGSVGASGDLAPLAHLCLPLIGEGEV
FYRGERLPAAAALQQAPLAPIQLSAKEGLALINGTQVSTALALDALLATERLFEAAVISGAVTLDAARGSDGPFDPRIHA
VRGQPGQIACAAAYRALMVGSEIRRSHLEGDDRVQDPYCLRCQPQVMGACLDQMRYASQVLMREANAVTDNPLVFASTQE
VAVQAGAVEPALPGHRSRPLEGEVATGHVGGELLSGGNFHAEPVALAADALAVVIAEIGAITERRIAMLVDTVVSRLPAF
LTPEPGLNSGFMIVHVTAAALASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLQPMLRNTEYIVAIELLTAAQGIE
FLRPLKSASVLEGVLQLVRSVSPAMMRDRSLAPDIGAVHQLVAQGRIGLAGEAQITELTALRLV

Sequences:

>Translated_544_residues
MNIQPGFLTLTQLRQIHAGSEPLTIDPSATAGIRASAQLVQQAAQGGAAVYGVNTGFGKLANQRIAQTDLNTLQLNLLRS
HAVGVGEPMPERVVRLVLLLKAASLARGFSGVRECVIDLLLALYNHGLTPVIPCQGSVGASGDLAPLAHLCLPLIGEGEV
FYRGERLPAAAALQQAPLAPIQLSAKEGLALINGTQVSTALALDALLATERLFEAAVISGAVTLDAARGSDGPFDPRIHA
VRGQPGQIACAAAYRALMVGSEIRRSHLEGDDRVQDPYCLRCQPQVMGACLDQMRYASQVLMREANAVTDNPLVFASTQE
VAVQAGAVEPALPGHRSRPLEGEVATGHVGGELLSGGNFHAEPVALAADALAVVIAEIGAITERRIAMLVDTVVSRLPAF
LTPEPGLNSGFMIVHVTAAALASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLQPMLRNTEYIVAIELLTAAQGIE
FLRPLKSASVLEGVLQLVRSVSPAMMRDRSLAPDIGAVHQLVAQGRIGLAGEAQITELTALRLV
>Mature_544_residues
MNIQPGFLTLTQLRQIHAGSEPLTIDPSATAGIRASAQLVQQAAQGGAAVYGVNTGFGKLANQRIAQTDLNTLQLNLLRS
HAVGVGEPMPERVVRLVLLLKAASLARGFSGVRECVIDLLLALYNHGLTPVIPCQGSVGASGDLAPLAHLCLPLIGEGEV
FYRGERLPAAAALQQAPLAPIQLSAKEGLALINGTQVSTALALDALLATERLFEAAVISGAVTLDAARGSDGPFDPRIHA
VRGQPGQIACAAAYRALMVGSEIRRSHLEGDDRVQDPYCLRCQPQVMGACLDQMRYASQVLMREANAVTDNPLVFASTQE
VAVQAGAVEPALPGHRSRPLEGEVATGHVGGELLSGGNFHAEPVALAADALAVVIAEIGAITERRIAMLVDTVVSRLPAF
LTPEPGLNSGFMIVHVTAAALASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLQPMLRNTEYIVAIELLTAAQGIE
FLRPLKSASVLEGVLQLVRSVSPAMMRDRSLAPDIGAVHQLVAQGRIGLAGEAQITELTALRLV

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=526, Percent_Identity=43.3460076045627, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17567831, Length=514, Percent_Identity=42.6070038910506, Blast_Score=357, Evalue=8e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 57042; Mature: 57042

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQPGFLTLTQLRQIHAGSEPLTIDPSATAGIRASAQLVQQAAQGGAAVYGVNTGFGKL
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ANQRIAQTDLNTLQLNLLRSHAVGVGEPMPERVVRLVLLLKAASLARGFSGVRECVIDLL
HHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALYNHGLTPVIPCQGSVGASGDLAPLAHLCLPLIGEGEVFYRGERLPAAAALQQAPLAP
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCC
IQLSAKEGLALINGTQVSTALALDALLATERLFEAAVISGAVTLDAARGSDGPFDPRIHA
EEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEE
VRGQPGQIACAAAYRALMVGSEIRRSHLEGDDRVQDPYCLRCQPQVMGACLDQMRYASQV
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
LMREANAVTDNPLVFASTQEVAVQAGAVEPALPGHRSRPLEGEVATGHVGGELLSGGNFH
HHHHHCCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCHHCCCCCCC
AEPVALAADALAVVIAEIGAITERRIAMLVDTVVSRLPAFLTPEPGLNSGFMIVHVTAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHH
LASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLQPMLRNTEYIVAIELLTAAQGIE
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
FLRPLKSASVLEGVLQLVRSVSPAMMRDRSLAPDIGAVHQLVAQGRIGLAGEAQITELTA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
LRLV
HHCC
>Mature Secondary Structure
MNIQPGFLTLTQLRQIHAGSEPLTIDPSATAGIRASAQLVQQAAQGGAAVYGVNTGFGKL
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ANQRIAQTDLNTLQLNLLRSHAVGVGEPMPERVVRLVLLLKAASLARGFSGVRECVIDLL
HHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALYNHGLTPVIPCQGSVGASGDLAPLAHLCLPLIGEGEVFYRGERLPAAAALQQAPLAP
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCCCCC
IQLSAKEGLALINGTQVSTALALDALLATERLFEAAVISGAVTLDAARGSDGPFDPRIHA
EEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEE
VRGQPGQIACAAAYRALMVGSEIRRSHLEGDDRVQDPYCLRCQPQVMGACLDQMRYASQV
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
LMREANAVTDNPLVFASTQEVAVQAGAVEPALPGHRSRPLEGEVATGHVGGELLSGGNFH
HHHHHCCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCHHCCCCCCC
AEPVALAADALAVVIAEIGAITERRIAMLVDTVVSRLPAFLTPEPGLNSGFMIVHVTAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHH
LASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLQPMLRNTEYIVAIELLTAAQGIE
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
FLRPLKSASVLEGVLQLVRSVSPAMMRDRSLAPDIGAVHQLVAQGRIGLAGEAQITELTA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
LRLV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]