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The map label for this gene is hutH [H]

Identifier: 91787054

GI number: 91787054

Start: 1197789

End: 1199309

Strand: Reverse

Name: hutH [H]

Synonym: Bpro_1157

Alternate gene names: 91787054

Gene position: 1199309-1197789 (Counterclockwise)

Preceding gene: 91787055

Following gene: 91787053

Centisome position: 23.06

GC content: 69.03

Gene sequence:

>1521_bases
ATGACGATTGAAGTCGGCGAAACATGGGTGGGCATAGCCGATCTGGTGCGCGTCGCCCGCCAGGGTGAAGCCGTCGCGCT
GGCACCCGGTGCCCGTGCGCGGGTTGCCGCGGCGCGCGATGTGGTAGTCCGCCTGGCGGCGTCCGGCGCGCCTGTTTATG
GCCTCAATTCCGCGCTGGGTGCCAACACGGGCGCACTGCTGGCGGAAGATGATCTGGAAGACTATCAGCGCCGGGCCGTG
CGTGCCCGCGCGGTGGCGGTCGGACCGGCTTATGAGCAGTCCAGTGTTCGCGCCATGCAATTTGCCCGCATCGCCGGCCT
GGCGCGCGGTGGCTCCGGCGTGTCACCCGGCGTGCTGGATGCCTGTATCGCGCTGCTGAACCACCGGGTGCACCCGGTGG
TGCCACGCTTCGGCTCCATTGGTGTGGCCGACCTGCCCCAGTTGTCGCATTTGGCCTTGCCCCTGTTCGGCGAAGGCGAG
GCCGAATTTGGCGGCGAGGTGCTCAAGGGCGGCGTTGCCCTGGAGCGCGCCGGGCTGCAGCCCGTCAAGCTCGGCGCCAA
GGACGGCCTGGCGCTGATCAGCTCCAACGCCGCCACCACCGCGCGTGCCGCACTGGTGCTGCATGACGCCACGGCCGCAC
TGGACGCCTGGCTGGCCGCGGTGGCGCTGGGATTCGAGGGCTTTCGCGCCAACTTGTCCCCGCTCCATCCCAGCGCGGTC
ATGGCCAGGCCCGCGACCGGCCAGGTGGAAGTTGCCAGCCAGCTGCGCGCGCTCCTGAAGGGCAGCGCACTGCTCGCGCC
GGGTGCCGCCCGCCGCGTTCAGGACCCGGTCTCGCTGCGTGTCGTGGCCCAGGTGCATGGCGCTGCCCGGGGCATGATAG
CCCTGGCCCGGGAGCAGGTCGAAATGGAACTCAACAGCGCCGCCGACAGCCCGCTGGTGCTGGCAGACGACGGCATCATG
CTGTCCAACGGAAACTTTCACGTGCCGGCCCTGGCGCTCGCGCTGGACGCCTGCGCGATTGCGCTGGCACAGGCCGCCAG
CATGTCTGTGGCCCGCTGCCAGCGCTTCATGTCACCCGCGCTCACCGGCCTGCCCCTGCAGCTGACACGCCACGGGCCAG
CCCATTCCGGCTTTGCCACGGTGCAAAAAACCCTGACCGCCCTGTGGGCCGAGATACGGTTGCGCGCCAACCCCGGCTCG
CTCGATTACCTGCCGGTCTCCGAAGGGCTGGAGGATCATGCGTGCATGGCGCTGGGCGTTGCCGAAAAACTGGGTGAACT
GCTGGAGCGCGTCCGCTACCTCATCGCCATTGAACTTCTGATCGCCGCCCAGGCCGTGGACCTGCGTGAAACCGATCAGG
CCACCATGGGTGAAGGCGCGCGCGCGACCTATCTGCAACTGCGCGACCTGGTCGCCATGCTGGACGAAGACCGCCCGCTG
GGCCCGGACATTGACCGGGTCCAACGCGCTGTAGCCTCGGGCTTGTTCAGTTCATGGGCCGTCAGTCCAGGGGCCGCGTG
A

Upstream 100 bases:

>100_bases
GGAACCCAAAGACGTGGCACGCGACTTCCTCAAAGCCAAGGGGCTGGTCAAGTAAGCCCCGCAGGTCACAAGCGCATCAG
CCAACGGGAACTGACAGCCC

Downstream 100 bases:

>100_bases
CACCGTTATGAAATGGTTCCTGCGCAACTGGACTGACATTGTGTATGCCCTGTGGGAACACATTGCCATCTCCCTGACGG
CGCTCACGATTGCATTCGCC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTIEVGETWVGIADLVRVARQGEAVALAPGARARVAAARDVVVRLAASGAPVYGLNSALGANTGALLAEDDLEDYQRRAV
RARAVAVGPAYEQSSVRAMQFARIAGLARGGSGVSPGVLDACIALLNHRVHPVVPRFGSIGVADLPQLSHLALPLFGEGE
AEFGGEVLKGGVALERAGLQPVKLGAKDGLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAV
MARPATGQVEVASQLRALLKGSALLAPGAARRVQDPVSLRVVAQVHGAARGMIALAREQVEMELNSAADSPLVLADDGIM
LSNGNFHVPALALALDACAIALAQAASMSVARCQRFMSPALTGLPLQLTRHGPAHSGFATVQKTLTALWAEIRLRANPGS
LDYLPVSEGLEDHACMALGVAEKLGELLERVRYLIAIELLIAAQAVDLRETDQATMGEGARATYLQLRDLVAMLDEDRPL
GPDIDRVQRAVASGLFSSWAVSPGAA

Sequences:

>Translated_506_residues
MTIEVGETWVGIADLVRVARQGEAVALAPGARARVAAARDVVVRLAASGAPVYGLNSALGANTGALLAEDDLEDYQRRAV
RARAVAVGPAYEQSSVRAMQFARIAGLARGGSGVSPGVLDACIALLNHRVHPVVPRFGSIGVADLPQLSHLALPLFGEGE
AEFGGEVLKGGVALERAGLQPVKLGAKDGLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAV
MARPATGQVEVASQLRALLKGSALLAPGAARRVQDPVSLRVVAQVHGAARGMIALAREQVEMELNSAADSPLVLADDGIM
LSNGNFHVPALALALDACAIALAQAASMSVARCQRFMSPALTGLPLQLTRHGPAHSGFATVQKTLTALWAEIRLRANPGS
LDYLPVSEGLEDHACMALGVAEKLGELLERVRYLIAIELLIAAQAVDLRETDQATMGEGARATYLQLRDLVAMLDEDRPL
GPDIDRVQRAVASGLFSSWAVSPGAA
>Mature_505_residues
TIEVGETWVGIADLVRVARQGEAVALAPGARARVAAARDVVVRLAASGAPVYGLNSALGANTGALLAEDDLEDYQRRAVR
ARAVAVGPAYEQSSVRAMQFARIAGLARGGSGVSPGVLDACIALLNHRVHPVVPRFGSIGVADLPQLSHLALPLFGEGEA
EFGGEVLKGGVALERAGLQPVKLGAKDGLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAVM
ARPATGQVEVASQLRALLKGSALLAPGAARRVQDPVSLRVVAQVHGAARGMIALAREQVEMELNSAADSPLVLADDGIML
SNGNFHVPALALALDACAIALAQAASMSVARCQRFMSPALTGLPLQLTRHGPAHSGFATVQKTLTALWAEIRLRANPGSL
DYLPVSEGLEDHACMALGVAEKLGELLERVRYLIAIELLIAAQAVDLRETDQATMGEGARATYLQLRDLVAMLDEDRPLG
PDIDRVQRAVASGLFSSWAVSPGAA

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=499, Percent_Identity=33.4669338677355, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17567831, Length=483, Percent_Identity=34.1614906832298, Blast_Score=197, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 52483; Mature: 52352

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEVGETWVGIADLVRVARQGEAVALAPGARARVAAARDVVVRLAASGAPVYGLNSALG
CEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCHHCC
ANTGALLAEDDLEDYQRRAVRARAVAVGPAYEQSSVRAMQFARIAGLARGGSGVSPGVLD
CCCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ACIALLNHRVHPVVPRFGSIGVADLPQLSHLALPLFGEGEAEFGGEVLKGGVALERAGLQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHCHHHHHCCHHHHHCCCC
PVKLGAKDGLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAV
CEEECCCCCEEEEECCCCHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MARPATGQVEVASQLRALLKGSALLAPGAARRVQDPVSLRVVAQVHGAARGMIALAREQV
EECCCCCCHHHHHHHHHHHCCCCEECCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHH
EMELNSAADSPLVLADDGIMLSNGNFHVPALALALDACAIALAQAASMSVARCQRFMSPA
HHHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLPLQLTRHGPAHSGFATVQKTLTALWAEIRLRANPGSLDYLPVSEGLEDHACMALGV
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCCHHHHHHHH
AEKLGELLERVRYLIAIELLIAAQAVDLRETDQATMGEGARATYLQLRDLVAMLDEDRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCC
GPDIDRVQRAVASGLFSSWAVSPGAA
CCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIEVGETWVGIADLVRVARQGEAVALAPGARARVAAARDVVVRLAASGAPVYGLNSALG
EEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCHHCC
ANTGALLAEDDLEDYQRRAVRARAVAVGPAYEQSSVRAMQFARIAGLARGGSGVSPGVLD
CCCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ACIALLNHRVHPVVPRFGSIGVADLPQLSHLALPLFGEGEAEFGGEVLKGGVALERAGLQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHCHHHHHCCHHHHHCCCC
PVKLGAKDGLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAV
CEEECCCCCEEEEECCCCHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
MARPATGQVEVASQLRALLKGSALLAPGAARRVQDPVSLRVVAQVHGAARGMIALAREQV
EECCCCCCHHHHHHHHHHHCCCCEECCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHH
EMELNSAADSPLVLADDGIMLSNGNFHVPALALALDACAIALAQAASMSVARCQRFMSPA
HHHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLPLQLTRHGPAHSGFATVQKTLTALWAEIRLRANPGSLDYLPVSEGLEDHACMALGV
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCCHHHHHHHH
AEKLGELLERVRYLIAIELLIAAQAVDLRETDQATMGEGARATYLQLRDLVAMLDEDRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCC
GPDIDRVQRAVASGLFSSWAVSPGAA
CCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA