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The map label for this gene is aroE [H]

Identifier: 91786985

GI number: 91786985

Start: 1119407

End: 1120267

Strand: Reverse

Name: aroE [H]

Synonym: Bpro_1087

Alternate gene names: 91786985

Gene position: 1120267-1119407 (Counterclockwise)

Preceding gene: 91786986

Following gene: 91786984

Centisome position: 21.54

GC content: 65.51

Gene sequence:

>861_bases
ATGGATAAGTATTTCGTCCTCGGCAACCCGATTCAACACAGCAAATCGCCGCAGATTCATGCACGCTTTGCCGAACTGAC
AGGCCAGACGCTGGAATACGACCGGCTGCTCACGCCGCTCGACGGCTTTGCCGCGACGCTCGCGCAACTGGTGCAGAGCG
GCGCGCGCGGCTGCAACGTCACGGTTCCGTTCAAATTCGAGGCCTTTCAGGCAGCCGGCACTCAGAGCGACCGGGCGCAG
CTGGCCCAGGCCGCCAACACCCTGAAGCTGGACGGCAACACCATTTACGCCGACAACACCGATGGCATAGGGCTCGTCAA
CGATATCCAGAACAACGCCGGTGTTTCACTGGCCGGTCGCGACGTCCTGCTCATAGGCGCCGGCGGCGCGGGTGCCGGCG
CGCTGGCACCGCTGCTGGCAGCCGGACCGCGCAGGCTGGTGCTGGCCAACCGCACCCGGGCCAAGGCCGATGCACTGGTG
TTGCGCCACACCCTGCACCCGTCCCTGCAGGAGGCGCTACAAAAAACAGAGCTATCAGCCCAGGATTTGCAGGGGATAGA
TGGTAGTTTTGATGTCGTGATCAATGCCAGCGCGAGCAGCCTGAGCGGTGGCGGCGTGCCAGTGGACAGCCGCGTGCTCA
AGCCGGGCGCGCTGGCGTACGACATGATGTATGGCCCTGCGGCGGACGGTTTCATGACCTGGGCCCGCGAACACGGCGCC
ACGCCACGTGACGGCCTGGGCATGCTGGTGGAGCAGGCCGCCGAGGCGTTTGCGCTGTGGCGCGGCGTGCGGCCGCCATC
GCAGCAGGTCCTGCAGGAAATGCGGACAGCCATGCAGACGCAGCAGACGCAGGCCAGATGA

Upstream 100 bases:

>100_bases
ACGCTGGAAACCCGGCTGACCAGCCGCTGAGCCTTCGCACGCCCCTTGCCGACAACGCCCCGATGCCAACCGCCTTCACT
CATGCATAAGCCTTGTATCC

Downstream 100 bases:

>100_bases
AAGCGCTGCTGCGCCTGCTGGGTCTGGTACTGTTGGCGGGTCTGGCCCTGCAGATTTATTTTGTGGCCCGGATCGCGCTG
ATGGCCGTGGTCAAACCCGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MDKYFVLGNPIQHSKSPQIHARFAELTGQTLEYDRLLTPLDGFAATLAQLVQSGARGCNVTVPFKFEAFQAAGTQSDRAQ
LAQAANTLKLDGNTIYADNTDGIGLVNDIQNNAGVSLAGRDVLLIGAGGAGAGALAPLLAAGPRRLVLANRTRAKADALV
LRHTLHPSLQEALQKTELSAQDLQGIDGSFDVVINASASSLSGGGVPVDSRVLKPGALAYDMMYGPAADGFMTWAREHGA
TPRDGLGMLVEQAAEAFALWRGVRPPSQQVLQEMRTAMQTQQTQAR

Sequences:

>Translated_286_residues
MDKYFVLGNPIQHSKSPQIHARFAELTGQTLEYDRLLTPLDGFAATLAQLVQSGARGCNVTVPFKFEAFQAAGTQSDRAQ
LAQAANTLKLDGNTIYADNTDGIGLVNDIQNNAGVSLAGRDVLLIGAGGAGAGALAPLLAAGPRRLVLANRTRAKADALV
LRHTLHPSLQEALQKTELSAQDLQGIDGSFDVVINASASSLSGGGVPVDSRVLKPGALAYDMMYGPAADGFMTWAREHGA
TPRDGLGMLVEQAAEAFALWRGVRPPSQQVLQEMRTAMQTQQTQAR
>Mature_286_residues
MDKYFVLGNPIQHSKSPQIHARFAELTGQTLEYDRLLTPLDGFAATLAQLVQSGARGCNVTVPFKFEAFQAAGTQSDRAQ
LAQAANTLKLDGNTIYADNTDGIGLVNDIQNNAGVSLAGRDVLLIGAGGAGAGALAPLLAAGPRRLVLANRTRAKADALV
LRHTLHPSLQEALQKTELSAQDLQGIDGSFDVVINASASSLSGGGVPVDSRVLKPGALAYDMMYGPAADGFMTWAREHGA
TPRDGLGMLVEQAAEAFALWRGVRPPSQQVLQEMRTAMQTQQTQAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=280, Percent_Identity=40.3571428571429, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1787983, Length=280, Percent_Identity=28.9285714285714, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=296, Percent_Identity=28.0405405405405, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30219; Mature: 30219

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYFVLGNPIQHSKSPQIHARFAELTGQTLEYDRLLTPLDGFAATLAQLVQSGARGCNV
CCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEE
TVPFKFEAFQAAGTQSDRAQLAQAANTLKLDGNTIYADNTDGIGLVNDIQNNAGVSLAGR
EEEEEEHHHHHCCCCHHHHHHHHHHCEEEECCCEEEECCCCCCCCHHHCCCCCCCEEECC
DVLLIGAGGAGAGALAPLLAAGPRRLVLANRTRAKADALVLRHTLHPSLQEALQKTELSA
CEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCH
QDLQGIDGSFDVVINASASSLSGGGVPVDSRVLKPGALAYDMMYGPAADGFMTWAREHGA
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCCCCHHHHHHHHCCC
TPRDGLGMLVEQAAEAFALWRGVRPPSQQVLQEMRTAMQTQQTQAR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKYFVLGNPIQHSKSPQIHARFAELTGQTLEYDRLLTPLDGFAATLAQLVQSGARGCNV
CCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEE
TVPFKFEAFQAAGTQSDRAQLAQAANTLKLDGNTIYADNTDGIGLVNDIQNNAGVSLAGR
EEEEEEHHHHHCCCCHHHHHHHHHHCEEEECCCEEEECCCCCCCCHHHCCCCCCCEEECC
DVLLIGAGGAGAGALAPLLAAGPRRLVLANRTRAKADALVLRHTLHPSLQEALQKTELSA
CEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCH
QDLQGIDGSFDVVINASASSLSGGGVPVDSRVLKPGALAYDMMYGPAADGFMTWAREHGA
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCCCCHHHHHHHHCCC
TPRDGLGMLVEQAAEAFALWRGVRPPSQQVLQEMRTAMQTQQTQAR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA