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The map label for this gene is nadB1 [H]

Identifier: 91786807

GI number: 91786807

Start: 923849

End: 925474

Strand: Reverse

Name: nadB1 [H]

Synonym: Bpro_0905

Alternate gene names: 91786807

Gene position: 925474-923849 (Counterclockwise)

Preceding gene: 91786808

Following gene: 91786803

Centisome position: 17.8

GC content: 66.73

Gene sequence:

>1626_bases
ATGACTGATTCAACTGCCCCCGTGCAACATGTGTTTGATGTGCTGGTGGTCGGCAGCGGCCTGGCCGGCCTGACGGCGGC
GCTGCAGCTGGCCCCCACCCACCGCGTGGCCGTGCTGACCAAGCGCGCCATGAACGACGGCTCCAGCGGCTGGGCCCAGG
GCGGCATTGCCGCCGTGATGGCCGAAGACGACAGCTTTGACTCGCACGTGGACGACACCCTGGTGGCGGGCGCAGGCCTG
TCGGATCCGGCCGCCACCCGCTTTGTGGTGGAAAACGCGCCGAAAACCATTGCCTGGCTGCAGGAGATGGGCGTGCCGTT
CTCGCAGGAAGACGGCCAGAACGGTCGCTTGCACCTGACGCGCGAGGGCGGCCACAGCGCCCGACGCATCGTGCATGTGA
CGGACGCCACCGGCGCCGCCGTGCAGCGCACGCTGATCGGGCAGGTACGCCGCACGCCCAACATCACGCTGTTCGAGAAC
CACACGCTGGTCGACCTGATCACCGCCCGCAAGCTGGGCCACACCTCGGCGGCTGAACCCGATCGCTGCCTCGGCCTGTA
TGCGCTGGACGAAGCCACCGACAAGGTACTCACCTTCAGCGCGCCGCACACCATCCTGGCCACTGGGGGCGCGGGCAAGG
TCTACCTGTACACCACCAACCCCGACACCGCCACCGGTGACGGCGTGGCGGCGGCCTGGCGCGCCGGTTGCCGCGCGGCC
AACATGGAATTCATCCAGTTCCACCCCACCTGCCTGTACCACCCGCATGCCAAATCGTTTTTGATCAGCGAGGCGGTGCG
TGGCGAAGGCGGGCGCCTGCTGCTGCCCGAATCGGCAGGGGGCACTCGCTTCATGCCCCTGCATGATGAGCGCGCCGAAC
TGGCGCCGCGCGATGTGGTGGCGCGCGCAATCGACTTCGAGATGAAAAAGCACGGCCTTGACTGCGTGCACCTGGACATT
TCACACCAGCCGCTGGCTTTTATCCTGGCCCATTTCCCCAATATCTACGCCCGCTGCCTTGAATTTGGCATCGACATTTC
GAAGCAGCCGATTCCCGTGGTGCCGGCAGCGCACTACACCTGCGGCGGCGTGCTGACCGACCTGGACGGCCGCACCGACC
TGCCCGGCCTGTATGCGATTGGCGAGACGGCCTGCACCGGCCTGCACGGCGCCAACCGGCTGGCCAGCAATTCGCTGGTG
GAATGCATGGTGTTTGCGCGCGCTGCGGCACAGGACATCGTTCGAACGCCGCGCCCCCGGGCGCCAGTACTTCCCGAATG
GGACGACAGCCGCGTCACCGACGCCGACGAGGCCGTGGTGATTTCGCACAACTGGGATGAACTGCGCCGCTTCATGTGGG
ACTACGTGGGCATCGTGCGGACCAACAAGCGCCTGGAGCGCGCCGCCCACCGCATCACGCTGCTGCAGGGCGAAATCCAG
GAGTACTACGCGCATTTCCATGTCACGCGCGATTTGCTGGAACTTCGCAACCTGGTGCAGGCGGCCGAACTGATTGTTCG
TTCGGCCCAGGCCCGGCATGAAAGCCGCGGCCTGCATTTCAGCCGCGATTACCCGGCCATGGCGGCCACGGCGACCCCGA
CCATCCTCGTGCCGCCAGCGGCCTGA

Upstream 100 bases:

>100_bases
CGAATTGTCCAAGGAAGGCCTGCTGGAAGTCACGCAGGCCGAAGCTTTTGCCCCGGTTTACGTGCGCCTGGCCTACACTC
CCGCCTGATATTCATCCTTC

Downstream 100 bases:

>100_bases
ACCGACGCGGGCATCAGGCGGTGCGGGGCTCCAGCTCCGCCGGGATCCAGCCGCGCAGGCTGTTCACAAAAGCCAGCGCC
TGCACCCGCGGCAGATCCGC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTDSTAPVQHVFDVLVVGSGLAGLTAALQLAPTHRVAVLTKRAMNDGSSGWAQGGIAAVMAEDDSFDSHVDDTLVAGAGL
SDPAATRFVVENAPKTIAWLQEMGVPFSQEDGQNGRLHLTREGGHSARRIVHVTDATGAAVQRTLIGQVRRTPNITLFEN
HTLVDLITARKLGHTSAAEPDRCLGLYALDEATDKVLTFSAPHTILATGGAGKVYLYTTNPDTATGDGVAAAWRAGCRAA
NMEFIQFHPTCLYHPHAKSFLISEAVRGEGGRLLLPESAGGTRFMPLHDERAELAPRDVVARAIDFEMKKHGLDCVHLDI
SHQPLAFILAHFPNIYARCLEFGIDISKQPIPVVPAAHYTCGGVLTDLDGRTDLPGLYAIGETACTGLHGANRLASNSLV
ECMVFARAAAQDIVRTPRPRAPVLPEWDDSRVTDADEAVVISHNWDELRRFMWDYVGIVRTNKRLERAAHRITLLQGEIQ
EYYAHFHVTRDLLELRNLVQAAELIVRSAQARHESRGLHFSRDYPAMAATATPTILVPPAA

Sequences:

>Translated_541_residues
MTDSTAPVQHVFDVLVVGSGLAGLTAALQLAPTHRVAVLTKRAMNDGSSGWAQGGIAAVMAEDDSFDSHVDDTLVAGAGL
SDPAATRFVVENAPKTIAWLQEMGVPFSQEDGQNGRLHLTREGGHSARRIVHVTDATGAAVQRTLIGQVRRTPNITLFEN
HTLVDLITARKLGHTSAAEPDRCLGLYALDEATDKVLTFSAPHTILATGGAGKVYLYTTNPDTATGDGVAAAWRAGCRAA
NMEFIQFHPTCLYHPHAKSFLISEAVRGEGGRLLLPESAGGTRFMPLHDERAELAPRDVVARAIDFEMKKHGLDCVHLDI
SHQPLAFILAHFPNIYARCLEFGIDISKQPIPVVPAAHYTCGGVLTDLDGRTDLPGLYAIGETACTGLHGANRLASNSLV
ECMVFARAAAQDIVRTPRPRAPVLPEWDDSRVTDADEAVVISHNWDELRRFMWDYVGIVRTNKRLERAAHRITLLQGEIQ
EYYAHFHVTRDLLELRNLVQAAELIVRSAQARHESRGLHFSRDYPAMAATATPTILVPPAA
>Mature_540_residues
TDSTAPVQHVFDVLVVGSGLAGLTAALQLAPTHRVAVLTKRAMNDGSSGWAQGGIAAVMAEDDSFDSHVDDTLVAGAGLS
DPAATRFVVENAPKTIAWLQEMGVPFSQEDGQNGRLHLTREGGHSARRIVHVTDATGAAVQRTLIGQVRRTPNITLFENH
TLVDLITARKLGHTSAAEPDRCLGLYALDEATDKVLTFSAPHTILATGGAGKVYLYTTNPDTATGDGVAAAWRAGCRAAN
MEFIQFHPTCLYHPHAKSFLISEAVRGEGGRLLLPESAGGTRFMPLHDERAELAPRDVVARAIDFEMKKHGLDCVHLDIS
HQPLAFILAHFPNIYARCLEFGIDISKQPIPVVPAAHYTCGGVLTDLDGRTDLPGLYAIGETACTGLHGANRLASNSLVE
CMVFARAAAQDIVRTPRPRAPVLPEWDDSRVTDADEAVVISHNWDELRRFMWDYVGIVRTNKRLERAAHRITLLQGEIQE
YYAHFHVTRDLLELRNLVQAAELIVRSAQARHESRGLHFSRDYPAMAATATPTILVPPAA

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=515, Percent_Identity=33.2038834951456, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1788928, Length=535, Percent_Identity=58.5046728971963, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1790597, Length=512, Percent_Identity=32.6171875, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1786942, Length=563, Percent_Identity=31.7939609236234, Blast_Score=202, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17505833, Length=533, Percent_Identity=32.0825515947467, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17550100, Length=540, Percent_Identity=31.8518518518519, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI71986328, Length=476, Percent_Identity=26.6806722689076, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322416, Length=565, Percent_Identity=33.8053097345133, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6322701, Length=562, Percent_Identity=32.7402135231317, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6322511, Length=493, Percent_Identity=26.7748478701826, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17137288, Length=574, Percent_Identity=34.4947735191638, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655642, Length=574, Percent_Identity=34.4947735191638, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24655647, Length=574, Percent_Identity=34.4947735191638, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24663005, Length=572, Percent_Identity=31.6433566433566, Blast_Score=221, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 58723; Mature: 58592

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTAPVQHVFDVLVVGSGLAGLTAALQLAPTHRVAVLTKRAMNDGSSGWAQGGIAAVM
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEE
AEDDSFDSHVDDTLVAGAGLSDPAATRFVVENAPKTIAWLQEMGVPFSQEDGQNGRLHLT
ECCCCCCCCCCCHHEECCCCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEEE
REGGHSARRIVHVTDATGAAVQRTLIGQVRRTPNITLFENHTLVDLITARKLGHTSAAEP
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHCCCCCCCCC
DRCLGLYALDEATDKVLTFSAPHTILATGGAGKVYLYTTNPDTATGDGVAAAWRAGCRAA
CCEEEEEEECCCCCCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCCCC
NMEFIQFHPTCLYHPHAKSFLISEAVRGEGGRLLLPESAGGTRFMPLHDERAELAPRDVV
CEEEEEECCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHCCHHHHH
ARAIDFEMKKHGLDCVHLDISHQPLAFILAHFPNIYARCLEFGIDISKQPIPVVPAAHYT
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
CGGVLTDLDGRTDLPGLYAIGETACTGLHGANRLASNSLVECMVFARAAAQDIVRTPRPR
CCCEEECCCCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
APVLPEWDDSRVTDADEAVVISHNWDELRRFMWDYVGIVRTNKRLERAAHRITLLQGEIQ
CCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYYAHFHVTRDLLELRNLVQAAELIVRSAQARHESRGLHFSRDYPAMAATATPTILVPPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCC
A
C
>Mature Secondary Structure 
TDSTAPVQHVFDVLVVGSGLAGLTAALQLAPTHRVAVLTKRAMNDGSSGWAQGGIAAVM
CCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEE
AEDDSFDSHVDDTLVAGAGLSDPAATRFVVENAPKTIAWLQEMGVPFSQEDGQNGRLHLT
ECCCCCCCCCCCHHEECCCCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEEE
REGGHSARRIVHVTDATGAAVQRTLIGQVRRTPNITLFENHTLVDLITARKLGHTSAAEP
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHCCCCCCCCC
DRCLGLYALDEATDKVLTFSAPHTILATGGAGKVYLYTTNPDTATGDGVAAAWRAGCRAA
CCEEEEEEECCCCCCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCCCC
NMEFIQFHPTCLYHPHAKSFLISEAVRGEGGRLLLPESAGGTRFMPLHDERAELAPRDVV
CEEEEEECCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHCCHHHHH
ARAIDFEMKKHGLDCVHLDISHQPLAFILAHFPNIYARCLEFGIDISKQPIPVVPAAHYT
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
CGGVLTDLDGRTDLPGLYAIGETACTGLHGANRLASNSLVECMVFARAAAQDIVRTPRPR
CCCEEECCCCCCCCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
APVLPEWDDSRVTDADEAVVISHNWDELRRFMWDYVGIVRTNKRLERAAHRITLLQGEIQ
CCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYYAHFHVTRDLLELRNLVQAAELIVRSAQARHESRGLHFSRDYPAMAATATPTILVPPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]