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The map label for this gene is groEL [H]

Identifier: 91786661

GI number: 91786661

Start: 777898

End: 779550

Strand: Reverse

Name: groEL [H]

Synonym: Bpro_0759

Alternate gene names: 91786661

Gene position: 779550-777898 (Counterclockwise)

Preceding gene: 91786662

Following gene: 91786660

Centisome position: 14.99

GC content: 59.65

Gene sequence:

>1653_bases
ATGGCAGCAAAAGACGTCATTTTCGGCGGCGAAGCCCGCGCACGCATGGTCGAGGGTGTGAACATCCTGGCCAACGCCGT
CAAGGTAACCCTGGGCCCCAAAGGCCGCAACGTGGTGCTCGAGCGCTCCTTCGGCGCCCCCACCGTGACCAAGGACGGTG
TGTCCGTTGCTAAAGAAATCGAACTCAAGGACAAGCTGCAGAACATGGGCGCCCAGATGGTCAAGGAAGTCGCTTCCAAG
ACGTCTGACATCGCAGGTGACGGCACCACGACCGCTACCGTTCTGGCTCAAGCCATTGTTCGCGAAGGCATGAAATATGT
CGCCGCCGGCATGAACCCGATGGACCTGAAGCGCGGTATCGACAAGGCCGTCACGGCACTGGTCGAAGAGCTGAAGAAAG
CATCGAAAGCCACCACCACCTCCAAAGAAATCGCCCAGGTCGGCTCGATTTCTGCCAACTCTGACGAAGCCATCGGCAAA
ATCATTGCCGATGCGATGGACAAAGTCGGCAAGGAAGGCGTGATCACCGTGGAAGACGGCAAATCACTCGAAAGCGAACT
CGACGTCGTTGAAGGCATGCAGTTTGACCGCGGCTACCTGTCGCCTTACTTCATCAACAACCCTGAAAAGCAGTCGGCGA
TTCTGGACAACCCGTTTGTTCTGCTCTATGACAAGAAAATCAGCAACATCCGTGACCTGCTGCCTACCCTGGAACAAGTC
GCCAAGGCTGGCCGTCCGCTGCTGATCATTGCCGAAGAAGTTGAAGGCGAAGCCCTGGCTACGCTGGTGGTCAACACCCT
GCGCGGCATCCTGAAAGTGGTTGCTGTCAAGGCGCCAGGCTTCGGCGATCGCCGCAAAGCCATGCTGGAAGACATCGCCT
GCCTGACCGGCGGCAAGGTGATCGCTGAAGAAGTTGGCATGTCGCTCGAAAAAGTGACGCTGGCCGACCTCGGCACGGCC
AAGCGCATCGAAGTGGGCAAGGAAAACACCATCATCATCGACGGTGCCGGCGAAGCCAAGGACATCGAAGCCCGCGTCAA
GCAGGTTCGCGTGCAGATCGAAGAAGCGACCAGCGACTACGACCGTGAAAAACTGCAAGAGCGCGTGGCCAAGCTGGCCG
GCGGTGTTGCCGTGATCAAGGTTGGCGCTGCCACCGAAGTCGAAATGAAAGAAAAGAAAGCCCGCGTCGAAGACGCCCTG
CACGCTACCCGCGCTGCCGTGGAAGAAGGCATTGTGGCTGGTGGCGGTGTGGCGCTGCTGCGCGCCAAGCAGGCTGCTGG
CGCCATCAAGGGCGACAACGCTGACCAGGAAGCCGGCATCAAGCTGGTGCTGCGCGCCATCGAAGCGCCTCTGCGCGAGA
TTGTGTACAACGCAGGTGGCGAAGCCTCTGTGGTGGTGAACGCTGTGTTGGCCGGCAAGGGCAACTACGGCTTCAATGCA
GCCAACGACACCTACGGCGACATGATCGAAATGGGTATTCTGGATCCCACGAAAGTGACCCGCACGGCCCTGCAGAACGC
TGCTTCCGTCGCATCGCTGATGCTGACGACCGAAGCCATGGTGGCCGAGGCTCCGAAAGATGAGTCTGGCGCCGGTGGCG
GCATGCCAGGCGGCATGGGTGGAATGGGCGGCATGGGCGATATGGGCATGTAA

Upstream 100 bases:

>100_bases
CGAGCTGCTCGTGATGAAAGAAGAAGACCTGTTTGCGGTCGTTGAGAAGTAATTTCTCGGCTCTTTCAATCCCTCATTAA
CTGAATCTGGAGAATTAAAC

Downstream 100 bases:

>100_bases
TATCCCGCTGAGCCGGCTCACCCTGGCTCAGACGCCAACAGGCCAAAAGGCCGCGGTGCTTTCGCACCGCGGCCTTTTTT
TTGTGCGTGACCCGTCCTGA

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1 [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASK
TSDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGIDKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGK
IIADAMDKVGKEGVITVEDGKSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQV
AKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKVIAEEVGMSLEKVTLADLGTA
KRIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDAL
HATRAAVEEGIVAGGGVALLRAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNA
ANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMGGMGGMGDMGM

Sequences:

>Translated_550_residues
MAAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASK
TSDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGIDKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGK
IIADAMDKVGKEGVITVEDGKSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQV
AKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKVIAEEVGMSLEKVTLADLGTA
KRIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDAL
HATRAAVEEGIVAGGGVALLRAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNA
ANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMGGMGGMGDMGM
>Mature_549_residues
AAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKT
SDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGIDKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGKI
IADAMDKVGKEGVITVEDGKSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQVA
KAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKVIAEEVGMSLEKVTLADLGTAK
RIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALH
ATRAAVEEGIVAGGGVALLRAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNAA
NDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMGGMGGMGDMGM

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=527, Percent_Identity=52.9411764705882, Blast_Score=541, Evalue=1e-154,
Organism=Homo sapiens, GI31542947, Length=527, Percent_Identity=52.9411764705882, Blast_Score=541, Evalue=1e-154,
Organism=Escherichia coli, GI1790586, Length=529, Percent_Identity=75.4253308128544, Blast_Score=791, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17555558, Length=530, Percent_Identity=52.8301886792453, Blast_Score=542, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI193210679, Length=226, Percent_Identity=50, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17564182, Length=559, Percent_Identity=24.3291592128801, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32566944, Length=221, Percent_Identity=27.1493212669683, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323288, Length=526, Percent_Identity=52.6615969581749, Blast_Score=544, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6322524, Length=387, Percent_Identity=25.0645994832041, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322350, Length=573, Percent_Identity=23.0366492146597, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322446, Length=580, Percent_Identity=21.3793103448276, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641193, Length=527, Percent_Identity=51.9924098671727, Blast_Score=544, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24641191, Length=527, Percent_Identity=51.9924098671727, Blast_Score=544, Evalue=1e-155,
Organism=Drosophila melanogaster, GI45550936, Length=527, Percent_Identity=50.853889943074, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI45550132, Length=527, Percent_Identity=50.853889943074, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI45550935, Length=527, Percent_Identity=50.853889943074, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI17864606, Length=556, Percent_Identity=44.4244604316547, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24584129, Length=526, Percent_Identity=37.4524714828897, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI19921262, Length=526, Percent_Identity=37.4524714828897, Blast_Score=337, Evalue=1e-92,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 57523; Mature: 57392

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEI
CCCCCEEECCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHH
ELKDKLQNMGAQMVKEVASKTSDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGKIIADAMDKVGKEGVITVEDG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCC
KSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQV
CCHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
AKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKV
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHH
IAEEVGMSLEKVTLADLGTAKRIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDY
HHHHHCCCHHHHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHH
DREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALL
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
ANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMG
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GMGGMGDMGM
CCCCCCCCCC
>Mature Secondary Structure 
AAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEI
CCCCEEECCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHH
ELKDKLQNMGAQMVKEVASKTSDIAGDGTTTATVLAQAIVREGMKYVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVTALVEELKKASKATTTSKEIAQVGSISANSDEAIGKIIADAMDKVGKEGVITVEDG
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCC
KSLESELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLYDKKISNIRDLLPTLEQV
CCHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
AKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIACLTGGKV
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHH
IAEEVGMSLEKVTLADLGTAKRIEVGKENTIIIDGAGEAKDIEARVKQVRVQIEEATSDY
HHHHHCCCHHHHHHHHCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHH
DREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALL
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RAKQAAGAIKGDNADQEAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGKGNYGFNA
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
ANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTEAMVAEAPKDESGAGGGMPGGMG
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GMGGMGDMGM
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA