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The map label for this gene is hipA [C]

Identifier: 91786522

GI number: 91786522

Start: 624764

End: 626014

Strand: Direct

Name: hipA [C]

Synonym: Bpro_0617

Alternate gene names: 91786522

Gene position: 624764-626014 (Clockwise)

Preceding gene: 91786521

Following gene: 91786530

Centisome position: 12.01

GC content: 57.71

Gene sequence:

>1251_bases
ATGATCCGCCTGCGCGTCTGGGCCAACGTCAGGCCCATGGGCTGGTTTGGCCATGAAGCTGGCGAATACTTTTTCGAGTA
TGACGCGCAGTGGCTGGAGCAGCCGGGTGCTTATGTGCTTGCACCGCAATTTACGCTGGTTGGCACTCGCTTCACAGGGC
CGCTGGTCCGCAGTTTTTTTGAAAATCTGCTGCCCGAGGGCACTGCACTGGACGACGTCATCGCCGCTTTGGCCTTGCGT
GACCCTTCGCCGTTTGAGCTATTAGGTCAATTGGGCAAGGAGTTGCCGGGCGTTTTGTCCTTGCTGCCTGAAGATGGGCA
GTCTGCCATGCTTCAGCAATATCGTCCCTTGCCCTATGAGGAGTTGAGTGAACGCATCCGTGGCCAGAAGCCACTGCTGG
TGTCCAACGAGCAGACCACCATGTCGCTGGCCGGTGCGCAGGAAAAGATGGGGTTGCGCTTTGACAAGCGCACAAACCAA
CTGTCTGAAAGTGTGGGTACGTCGCACACCACCCACATACTCAAACCCGATACACGTCAGAAGCGCTACCAGCCCAGCGC
GCTGAATGAATACGCGTGCATGAAGCTGGCGCGGGCCCTGAAGTTGCCGGTGAATGACGTCTGGTTCCTGCGTGTGCCTG
AACCCGTGTACCTCGTGGAGCGCTATGACCGCGTGAATCTGGCCGGCAACATCGTTGGCCTGCATCAGTTTGACGGTTGC
CAATTGCTGGGCCATGGGTCGGGCTGGAAATATGAGCGGCAGGGTGGCCTGGCGAGTGTCCCCAAACTGGTAGCCGCCTT
GCGCGCTTTACCGGTCCGCGGCAGCGATCTGCTCAAGCTGCAGCAGTGGGTCATGTTCAATTACCTGATCGGCAATGCCG
ACGCGCATGCCAAAAATCTGTCGGTGCTGGTGGACGAAAAAGGTTTCCGCCTGGCTCCGTTTTACGACCTGCTGTGCGTG
CGGGCGTACGGCGACACGGGTCTTGCGCTGCATATTGGTGACGAGGACGCGTTCGATGCGGTGGGCGCGCACTCATGGGA
AGCCCTTTGCAAAGACTGCGGGTTTCGCCTGCCCGAGACATTAAAAGGTTTCCGCAAAATGGCGCAAGATCTTTTGCCGG
CCTGGCAAAAGACAAAAGCGGCCATCATCAAGGACGTTGCACCCGAAAAACGTGAGCTTGAGTTGCTGGAAAAAATGACA
GACGTCTTTGAAATGCACAGTGCGCATGCGATCTCGATGACAGGCGGCTGA

Upstream 100 bases:

>100_bases
TGCAGCTGACCCAAGGGCTGGGCCTGACGCTGACGCTGACAGGCTGGCAGATTGGGGGAACTACCAGTGATTCCCACCCC
AATACCAAAGTCAGCACCTC

Downstream 100 bases:

>100_bases
GTTCACGGCACAAAAGAACGGGAAAAGAGTGAAAACAAAACCATGGCAAGCTCCAATTTGCCTCACCCCCTAGACGTCCG
CAGCGCCCCGCAGGTGAAAC

Product: HipA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MIRLRVWANVRPMGWFGHEAGEYFFEYDAQWLEQPGAYVLAPQFTLVGTRFTGPLVRSFFENLLPEGTALDDVIAALALR
DPSPFELLGQLGKELPGVLSLLPEDGQSAMLQQYRPLPYEELSERIRGQKPLLVSNEQTTMSLAGAQEKMGLRFDKRTNQ
LSESVGTSHTTHILKPDTRQKRYQPSALNEYACMKLARALKLPVNDVWFLRVPEPVYLVERYDRVNLAGNIVGLHQFDGC
QLLGHGSGWKYERQGGLASVPKLVAALRALPVRGSDLLKLQQWVMFNYLIGNADAHAKNLSVLVDEKGFRLAPFYDLLCV
RAYGDTGLALHIGDEDAFDAVGAHSWEALCKDCGFRLPETLKGFRKMAQDLLPAWQKTKAAIIKDVAPEKRELELLEKMT
DVFEMHSAHAISMTGG

Sequences:

>Translated_416_residues
MIRLRVWANVRPMGWFGHEAGEYFFEYDAQWLEQPGAYVLAPQFTLVGTRFTGPLVRSFFENLLPEGTALDDVIAALALR
DPSPFELLGQLGKELPGVLSLLPEDGQSAMLQQYRPLPYEELSERIRGQKPLLVSNEQTTMSLAGAQEKMGLRFDKRTNQ
LSESVGTSHTTHILKPDTRQKRYQPSALNEYACMKLARALKLPVNDVWFLRVPEPVYLVERYDRVNLAGNIVGLHQFDGC
QLLGHGSGWKYERQGGLASVPKLVAALRALPVRGSDLLKLQQWVMFNYLIGNADAHAKNLSVLVDEKGFRLAPFYDLLCV
RAYGDTGLALHIGDEDAFDAVGAHSWEALCKDCGFRLPETLKGFRKMAQDLLPAWQKTKAAIIKDVAPEKRELELLEKMT
DVFEMHSAHAISMTGG
>Mature_416_residues
MIRLRVWANVRPMGWFGHEAGEYFFEYDAQWLEQPGAYVLAPQFTLVGTRFTGPLVRSFFENLLPEGTALDDVIAALALR
DPSPFELLGQLGKELPGVLSLLPEDGQSAMLQQYRPLPYEELSERIRGQKPLLVSNEQTTMSLAGAQEKMGLRFDKRTNQ
LSESVGTSHTTHILKPDTRQKRYQPSALNEYACMKLARALKLPVNDVWFLRVPEPVYLVERYDRVNLAGNIVGLHQFDGC
QLLGHGSGWKYERQGGLASVPKLVAALRALPVRGSDLLKLQQWVMFNYLIGNADAHAKNLSVLVDEKGFRLAPFYDLLCV
RAYGDTGLALHIGDEDAFDAVGAHSWEALCKDCGFRLPETLKGFRKMAQDLLPAWQKTKAAIIKDVAPEKRELELLEKMT
DVFEMHSAHAISMTGG

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=355, Percent_Identity=32.6760563380282, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 46615; Mature: 46615

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLRVWANVRPMGWFGHEAGEYFFEYDAQWLEQPGAYVLAPQFTLVGTRFTGPLVRSFF
CEEEEEECCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEECCEEEEECCCCHHHHHHHH
ENLLPEGTALDDVIAALALRDPSPFELLGQLGKELPGVLSLLPEDGQSAMLQQYRPLPYE
HHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCHH
ELSERIRGQKPLLVSNEQTTMSLAGAQEKMGLRFDKRTNQLSESVGTSHTTHILKPDTRQ
HHHHHHCCCCCEEECCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHHH
KRYQPSALNEYACMKLARALKLPVNDVWFLRVPEPVYLVERYDRVNLAGNIVGLHQFDGC
HCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCCCCCCCCCEEEEEECCCE
QLLGHGSGWKYERQGGLASVPKLVAALRALPVRGSDLLKLQQWVMFNYLIGNADAHAKNL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SVLVDEKGFRLAPFYDLLCVRAYGDTGLALHIGDEDAFDAVGAHSWEALCKDCGFRLPET
EEEEECCCCEECCHHHHHEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCHH
LKGFRKMAQDLLPAWQKTKAAIIKDVAPEKRELELLEKMTDVFEMHSAHAISMTGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MIRLRVWANVRPMGWFGHEAGEYFFEYDAQWLEQPGAYVLAPQFTLVGTRFTGPLVRSFF
CEEEEEECCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEECCEEEEECCCCHHHHHHHH
ENLLPEGTALDDVIAALALRDPSPFELLGQLGKELPGVLSLLPEDGQSAMLQQYRPLPYE
HHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCCHH
ELSERIRGQKPLLVSNEQTTMSLAGAQEKMGLRFDKRTNQLSESVGTSHTTHILKPDTRQ
HHHHHHCCCCCEEECCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHHH
KRYQPSALNEYACMKLARALKLPVNDVWFLRVPEPVYLVERYDRVNLAGNIVGLHQFDGC
HCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHCCCCCCCCCEEEEEECCCE
QLLGHGSGWKYERQGGLASVPKLVAALRALPVRGSDLLKLQQWVMFNYLIGNADAHAKNL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SVLVDEKGFRLAPFYDLLCVRAYGDTGLALHIGDEDAFDAVGAHSWEALCKDCGFRLPET
EEEEECCCCEECCHHHHHEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCHH
LKGFRKMAQDLLPAWQKTKAAIIKDVAPEKRELELLEKMTDVFEMHSAHAISMTGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]