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The map label for this gene is ywbI [H]

Identifier: 91786492

GI number: 91786492

Start: 590676

End: 591569

Strand: Direct

Name: ywbI [H]

Synonym: Bpro_0586

Alternate gene names: 91786492

Gene position: 590676-591569 (Clockwise)

Preceding gene: 91786477

Following gene: 91786501

Centisome position: 11.36

GC content: 66.44

Gene sequence:

>894_bases
ATGAAATTTGATCTCACCGATCTAAGGCTGTTTGTGCTGGTTGCGGACGAGGGCAGCCTGACGCGGGCGGCCCAGCGCCA
GCATCTGTCACTGGCGGCGGCCAGCAGCCGCATCAAGTCGCTGGAAACCCAGGCGGGCCAGCCCCTGCTGTACCGTGAAG
CCCGTGGCGTGCGCCTGACGCCGCCCGGCGAGGCGTTTTTGCACCACGCCCGGGGGGTGCTGCGCCAGGTGGACCAGTTA
CGCGTCGACCTGCAGGAATACGGGGGTGGCCTGCGCGGCCATGTGCGGGTTTTCGCCAACACCACGGCGGTGACGGATTT
CCTGCCGGAAATCCTGCCCGGCTTCCTCGCGGACAACCCCCGCGTGAACGTGGACCTTCAGGAAAAACCGAACGCTGAAA
TCGCCCGGGGCGTGCTGGACGGCCGTGCCGACATCGGCATTGTGGCCGGCAGGGTCGACACGCTGGGGCTGCAGGCCATT
CACTTCAGCACCGATCGCCTGGTGCTGGTCACGTCGCGCCAGCACCGCTTTGCCGGGCGCAAGACCATCGCTTTTGCCGA
GACACTGGACGAAGACGCGGTGGGCATGCACCACGGCAGCACGCTGCAGACTTTTCTGGCCACGGTGACGGAGTCACTGG
GCAAGCCGCTCAAGCTGCGCATCCAGCTGGCCAGCTTTGATGCGATGTGCCGCATGATAGGCAGCGGTGTGGGCGTGGGC
ATCGTGCCGGAGTCGGCGGCCCGGCGCAACCGGGATACGATGAACCTGGCGCTGATCGAGCTCACCGACGAGTGGAGCGT
GCGCGAGCGCTACATCCTCGTGCGCGACCAGGCCGCCTTGCCGGCCTACGCCCTGGCGTTGATCGACACTCTGTGCGCGC
ATTACCAGGCCTGA

Upstream 100 bases:

>100_bases
CCGTATGGTCGCCGCAGCCACTCCCCAGCGCAATCACTGATTTTCAAACCAAGGCTTCGGATTTATTGAAGGCTTGCCGG
GTTTGCGCTAGCATGACACG

Downstream 100 bases:

>100_bases
CGCGGCTGACGCGGCTGACGCGGCTGATGCGGCCTCAGTCCGGCAGCACGGCCGTCACTTCAATCTCGACCCGGGCCCGC
GCTTCCACCAGCCCGGCGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKFDLTDLRLFVLVADEGSLTRAAQRQHLSLAAASSRIKSLETQAGQPLLYREARGVRLTPPGEAFLHHARGVLRQVDQL
RVDLQEYGGGLRGHVRVFANTTAVTDFLPEILPGFLADNPRVNVDLQEKPNAEIARGVLDGRADIGIVAGRVDTLGLQAI
HFSTDRLVLVTSRQHRFAGRKTIAFAETLDEDAVGMHHGSTLQTFLATVTESLGKPLKLRIQLASFDAMCRMIGSGVGVG
IVPESAARRNRDTMNLALIELTDEWSVRERYILVRDQAALPAYALALIDTLCAHYQA

Sequences:

>Translated_297_residues
MKFDLTDLRLFVLVADEGSLTRAAQRQHLSLAAASSRIKSLETQAGQPLLYREARGVRLTPPGEAFLHHARGVLRQVDQL
RVDLQEYGGGLRGHVRVFANTTAVTDFLPEILPGFLADNPRVNVDLQEKPNAEIARGVLDGRADIGIVAGRVDTLGLQAI
HFSTDRLVLVTSRQHRFAGRKTIAFAETLDEDAVGMHHGSTLQTFLATVTESLGKPLKLRIQLASFDAMCRMIGSGVGVG
IVPESAARRNRDTMNLALIELTDEWSVRERYILVRDQAALPAYALALIDTLCAHYQA
>Mature_297_residues
MKFDLTDLRLFVLVADEGSLTRAAQRQHLSLAAASSRIKSLETQAGQPLLYREARGVRLTPPGEAFLHHARGVLRQVDQL
RVDLQEYGGGLRGHVRVFANTTAVTDFLPEILPGFLADNPRVNVDLQEKPNAEIARGVLDGRADIGIVAGRVDTLGLQAI
HFSTDRLVLVTSRQHRFAGRKTIAFAETLDEDAVGMHHGSTLQTFLATVTESLGKPLKLRIQLASFDAMCRMIGSGVGVG
IVPESAARRNRDTMNLALIELTDEWSVRERYILVRDQAALPAYALALIDTLCAHYQA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=187, Percent_Identity=30.4812834224599, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=27.4193548387097, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=24.0816326530612, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=28.1746031746032, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=27.4590163934426, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787806, Length=282, Percent_Identity=23.4042553191489, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790208, Length=281, Percent_Identity=28.1138790035587, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=25.1748251748252, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786713, Length=259, Percent_Identity=27.7992277992278, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=146, Percent_Identity=34.9315068493151, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=159, Percent_Identity=28.9308176100629, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=26.530612244898, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082132, Length=267, Percent_Identity=25.4681647940075, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32582; Mature: 32582

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDLTDLRLFVLVADEGSLTRAAQRQHLSLAAASSRIKSLETQAGQPLLYREARGVRLT
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEC
PPGEAFLHHARGVLRQVDQLRVDLQEYGGGLRGHVRVFANTTAVTDFLPEILPGFLADNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCC
RVNVDLQEKPNAEIARGVLDGRADIGIVAGRVDTLGLQAIHFSTDRLVLVTSRQHRFAGR
EEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHCCEEEEEECCCEEEEEECCCHHHCCC
KTIAFAETLDEDAVGMHHGSTLQTFLATVTESLGKPLKLRIQLASFDAMCRMIGSGVGVG
CEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCCEE
IVPESAARRNRDTMNLALIELTDEWSVRERYILVRDQAALPAYALALIDTLCAHYQA
ECCCHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFDLTDLRLFVLVADEGSLTRAAQRQHLSLAAASSRIKSLETQAGQPLLYREARGVRLT
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEC
PPGEAFLHHARGVLRQVDQLRVDLQEYGGGLRGHVRVFANTTAVTDFLPEILPGFLADNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCCC
RVNVDLQEKPNAEIARGVLDGRADIGIVAGRVDTLGLQAIHFSTDRLVLVTSRQHRFAGR
EEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHCCEEEEEECCCEEEEEECCCHHHCCC
KTIAFAETLDEDAVGMHHGSTLQTFLATVTESLGKPLKLRIQLASFDAMCRMIGSGVGVG
CEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCCEE
IVPESAARRNRDTMNLALIELTDEWSVRERYILVRDQAALPAYALALIDTLCAHYQA
ECCCHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]