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The map label for this gene is mdlA [H]

Identifier: 91786444

GI number: 91786444

Start: 535551

End: 536645

Strand: Direct

Name: mdlA [H]

Synonym: Bpro_0536

Alternate gene names: 91786444

Gene position: 535551-536645 (Clockwise)

Preceding gene: 91786443

Following gene: 91786449

Centisome position: 10.3

GC content: 63.84

Gene sequence:

>1095_bases
ATGAGCCCGCAACATCTCACGGTGCGGGCCATTGAAGCAACACTGGTGGTTGTACCCATGCGGCGGGCACTTGGCACCAG
CGCCATGCGGGTGACACAGGCACCACTGCTGCTATTGGACTTGCAAACAGAAGAAGGCATTACGGGCCGTGCGTACCTGT
TCTGCTACCTTGAAGCGGCCGGCGCGGCCGCTCTTGCGCTGGTACGCGACATCAACGCCGAGCTTGTGGGGAAAACGGCA
GCGCCCGCCGCGGTGCGGCGTGCGCTGGAAGCGCGGTTTCGCCTCCTGGGCGCACGCGGTATCGTGTCCATGCTCATGGC
GGGGATTGACATCGCCTGTTGGGACGCGCTGGCCATTTGCGCCGGGCTGCCACTTGCAACGCTACTGGGCGCCCAGCCCA
GGCCTATCCCCGCCTACAACAGCAACGGCCTGGGTTTGCTGGACGCGCGGGCCGCGGCCGATGAGGCCCTGGAACTGGTC
AGTGAGGGGTTTCATGCCATCAAAATGCGCCTGGGGCGCCCGCTGGCCAAAGACGACTTGGCCGCCGTGCGGGCTGTCAA
GCAAGCCCTACCAGCCGGGATTGCGCTGATGGCCGACTTCAACCAGGCGTTAAGCCGCAACGCTGCTGTCGAGCGATGCC
AGCAGCTTGATGATGAGGGCCTGTACTGGATTGAAGAACCGGTTCGCCATGACGATTACGCCACCAGTGCCGAACTGACC
GCCTTGCTGCGCACACCCGTCCAGATTGGGGAAAACTTTGCCGGCCCTCGTGCCATGGCCCAGGCACTGGCGCAGCGCGC
CTGCGACTTTGTCATGCCGGACCTGGAACGCATCGGCGGCGTGAGTGGCTGGATCGATGCCTCGGCGCTTGCCAATGTTG
CTGGCATTGAATTTTCGTCGCACCTGTTTCCCGAAGTCAGTGCGCACCTGCTGGCAGGCACGCCTACAGCACACTGGATC
GAGTACGTCGATTGGGCCGACGCCATTCTGCAGGAGCCGCTGAAAGTGGTGGACGGCTGCCTGTCAGCGCCCGACCGGCC
TGGCAACGGCCTGTCTTGGGATCTGGGCGCCGTGAAGCACTACCAGAAAGTGTGA

Upstream 100 bases:

>100_bases
GCGGCGACGTGGTGCACAGGGGCGCCCGCCTCGGGGTGGCCACGCCCTGCAATCGGGCCATCCTTGATATTCTGTCTGTG
CACAGTGAGGGGCGTACTGC

Downstream 100 bases:

>100_bases
GTCGTGAGGCCCTTGTCGAGGAACACAGGATGAAGCCTTCCAATCGCCCACGGTCGGCCCGACTCATGCACAGCGGAGTC
AGCAGGCATATGAACGGCGC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: MR [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSPQHLTVRAIEATLVVVPMRRALGTSAMRVTQAPLLLLDLQTEEGITGRAYLFCYLEAAGAAALALVRDINAELVGKTA
APAAVRRALEARFRLLGARGIVSMLMAGIDIACWDALAICAGLPLATLLGAQPRPIPAYNSNGLGLLDARAAADEALELV
SEGFHAIKMRLGRPLAKDDLAAVRAVKQALPAGIALMADFNQALSRNAAVERCQQLDDEGLYWIEEPVRHDDYATSAELT
ALLRTPVQIGENFAGPRAMAQALAQRACDFVMPDLERIGGVSGWIDASALANVAGIEFSSHLFPEVSAHLLAGTPTAHWI
EYVDWADAILQEPLKVVDGCLSAPDRPGNGLSWDLGAVKHYQKV

Sequences:

>Translated_364_residues
MSPQHLTVRAIEATLVVVPMRRALGTSAMRVTQAPLLLLDLQTEEGITGRAYLFCYLEAAGAAALALVRDINAELVGKTA
APAAVRRALEARFRLLGARGIVSMLMAGIDIACWDALAICAGLPLATLLGAQPRPIPAYNSNGLGLLDARAAADEALELV
SEGFHAIKMRLGRPLAKDDLAAVRAVKQALPAGIALMADFNQALSRNAAVERCQQLDDEGLYWIEEPVRHDDYATSAELT
ALLRTPVQIGENFAGPRAMAQALAQRACDFVMPDLERIGGVSGWIDASALANVAGIEFSSHLFPEVSAHLLAGTPTAHWI
EYVDWADAILQEPLKVVDGCLSAPDRPGNGLSWDLGAVKHYQKV
>Mature_363_residues
SPQHLTVRAIEATLVVVPMRRALGTSAMRVTQAPLLLLDLQTEEGITGRAYLFCYLEAAGAAALALVRDINAELVGKTAA
PAAVRRALEARFRLLGARGIVSMLMAGIDIACWDALAICAGLPLATLLGAQPRPIPAYNSNGLGLLDARAAADEALELVS
EGFHAIKMRLGRPLAKDDLAAVRAVKQALPAGIALMADFNQALSRNAAVERCQQLDDEGLYWIEEPVRHDDYATSAELTA
LLRTPVQIGENFAGPRAMAQALAQRACDFVMPDLERIGGVSGWIDASALANVAGIEFSSHLFPEVSAHLLAGTPTAHWIE
YVDWADAILQEPLKVVDGCLSAPDRPGNGLSWDLGAVKHYQKV

Specific function: Probably Involved In The Degradation Of Homoserine Lactone (Hsl) Or Of A Metabolite Of Hsl That Signals Starvation. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.1.2.2 [H]

Molecular weight: Translated: 38825; Mature: 38694

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQHLTVRAIEATLVVVPMRRALGTSAMRVTQAPLLLLDLQTEEGITGRAYLFCYLEAA
CCCCCEEEEEHHHHHEEEEHHHHHCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHH
GAAALALVRDINAELVGKTAAPAAVRRALEARFRLLGARGIVSMLMAGIDIACWDALAIC
HHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGLPLATLLGAQPRPIPAYNSNGLGLLDARAAADEALELVSEGFHAIKMRLGRPLAKDDL
HCCHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAVRAVKQALPAGIALMADFNQALSRNAAVERCQQLDDEGLYWIEEPVRHDDYATSAELT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHH
ALLRTPVQIGENFAGPRAMAQALAQRACDFVMPDLERIGGVSGWIDASALANVAGIEFSS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHCCCHHH
HLFPEVSAHLLAGTPTAHWIEYVDWADAILQEPLKVVDGCLSAPDRPGNGLSWDLGAVKH
HHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
YQKV
HHCC
>Mature Secondary Structure 
SPQHLTVRAIEATLVVVPMRRALGTSAMRVTQAPLLLLDLQTEEGITGRAYLFCYLEAA
CCCCEEEEEHHHHHEEEEHHHHHCHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEHHH
GAAALALVRDINAELVGKTAAPAAVRRALEARFRLLGARGIVSMLMAGIDIACWDALAIC
HHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGLPLATLLGAQPRPIPAYNSNGLGLLDARAAADEALELVSEGFHAIKMRLGRPLAKDDL
HCCHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAVRAVKQALPAGIALMADFNQALSRNAAVERCQQLDDEGLYWIEEPVRHDDYATSAELT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHH
ALLRTPVQIGENFAGPRAMAQALAQRACDFVMPDLERIGGVSGWIDASALANVAGIEFSS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHCCCHHH
HLFPEVSAHLLAGTPTAHWIEYVDWADAILQEPLKVVDGCLSAPDRPGNGLSWDLGAVKH
HHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
YQKV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2831968; 2271624; 2215699; 1909893; 1892834; 7893689; 7893690 [H]