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The map label for this gene is xylR [H]

Identifier: 91786038

GI number: 91786038

Start: 129205

End: 131019

Strand: Reverse

Name: xylR [H]

Synonym: Bpro_0127

Alternate gene names: 91786038

Gene position: 131019-129205 (Counterclockwise)

Preceding gene: 91786046

Following gene: 91786037

Centisome position: 2.52

GC content: 63.75

Gene sequence:

>1815_bases
ATGGGCAACACTTCGCGCATCTCCCTGGCCGACGTGGCCCGGGCCACGGGCACGACCCTTGGCAACTTCGACAGCGCATT
GGTGGCAAAAGCCCTGGGCGGATTTGCCAATGCCCACATTGGCGGCGATGCCCACCCCAACATTGCCGACATCAGCGAAT
GCCTGTTTTTTTCTCCGGGGGACGGACGCATCTGGCTGCAAGACCAGCGCATGGTCTTGTTGCACACGGAAGCCCTGGGC
TCCCTGCGGCGCGAAATGATTGACAGCCTGGGGCTGGAGCAGGCCCGCGGACTGTTCACCCGTGCGGGCTATGTCAGCGG
CGCCCGCGATGCCCAACTGGTGCGGCGGCAGTGGCCCGATGCAGACCCGTCGGCCATCGCCCTCGCGGGTACGCGCCTGC
ATGCGCTGGAGGGGGTGGTGAAAGTCGAGGTGGTGCGGGCCTCGTACAAGCCGGAAACGGGCAGCTATGAAGGCGAATTT
CTGTGGCACAACTCCAGCGAAGACGATGAACACATCGCCGCCTACGGGATTGGCGGCTCACCCGCCTGCTGGATGCAGGT
GGGCTATGCCACGGGCTATGTCAGCACATTGTTCGGCCATCTCGTCGTCTTCCGGGAAACGCAGTGTCGCTCCATGGGCG
AAGCGCATTGCCAGGTGGTAGGCAAATCGGCCGACCAGTGGGACGATATCGCGCAAGACATGCGCTACCTCAACGTCAGG
GAGTTTGTCGATACCGCAGCCTACGCCCGCCCAGCCCCCAGCGCCGCCGAACTGCCCCAGGTCGAGGCCTCCGCCGGCGA
TGCGATGGTCGGCGCCTCCTCGGCCTTCAACGCCGCCTGCCACCAGCTGAGCCGCGTGGCGCGTACCTCGGCCACCGTGC
TGTTTACCGGCGAGTCCGGCGTGGGCAAGGAAAAATTTGCCCGCATGCTGCACAAGATCAGCCCGCGCAAGGACCGGCCG
TTTGTGGCGGTGAACTGCGCAGCCATCCCGGAAACCCTGATCGAGTCCGAACTGTTCGGCGTGGAACGCGGGGCGTACAC
CGGAGCCAGCCACTCGCGGCCAGGCCGCTTTGAGAGAGCCAGCGGCGGCACCCTGTTTCTGGACGAGATTGGCTCGCTGA
GCTACGTCGCCCAAGGCAAGCTGCTGCGCGCCTTGCAGGAGGGCGAGGTCGAACGGGTGGGCGGCACGCGCAGCATTGCA
GTGGATGTGCGCGTCGTGGCGGCTACCAATGAAGCGCTGCGTCAAGCCGTGCTGGAGGGAAAGTTTCGCGAGGATTTGTT
CTTTCGGCTCAATGTCTTCCCCATTCACCTGCCGCCCCTGCGCGAGCGGCGTGATGACATTCCCCTGTTGATGAACCACT
TTCTGAACCATTACCGGCGCAAGCACGGCTGCAACACTGGCGGCTTCACGCAGGCAGCGGTTCGGTCCCTGCTGAACTAT
GCCTTTCCAGGCAACATCCGCGAACTGCAAAACCTGATCGAACGCGCTGTGATCATGGCCGACATGGAAGGGCTGATTGA
TGTGCACCACTTATTCACCAGCGGTGAAACCCTGAGCGCCGACATCATGACGCTGCGGCTGAAGGGAAGCTCCGCAACTT
TGAACTTCGCAGAGCCTGCAGGCTGCGCACAAGCCTTGGCGATAGCCACACCGTCAAGCACGGCGCAGGCTCCGCAGTCT
CTGGATCAGACCGAGCGCGACACGCTCCTGCGGGCGATTTCCACATCCCAGGGGAATCTGTCCGCCGCAGCGCGGCTGCT
CAACACAACGCGGGCGAAGCTGGCCTACCGCGCAAGAAAGCATCGCCTCCTTTGA

Upstream 100 bases:

>100_bases
TACTGCGGCGCAGCAAAGGGAAATCCCTGTTTTATTTTTTGATCAAATGGTTATAAATGTGAACTACATTTGCGCAATTG
ATTAAATAAAAAGTAAACCC

Downstream 100 bases:

>100_bases
TTCGCGCACACTTGCCTTGAGGTTTCGGGCTGCCCCGCCAGCTTCGGCCCCCAACCCGCTCACCCATCCAGCATCGCACC
CAGGCGGGAGGGCCGCCAAG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MGNTSRISLADVARATGTTLGNFDSALVAKALGGFANAHIGGDAHPNIADISECLFFSPGDGRIWLQDQRMVLLHTEALG
SLRREMIDSLGLEQARGLFTRAGYVSGARDAQLVRRQWPDADPSAIALAGTRLHALEGVVKVEVVRASYKPETGSYEGEF
LWHNSSEDDEHIAAYGIGGSPACWMQVGYATGYVSTLFGHLVVFRETQCRSMGEAHCQVVGKSADQWDDIAQDMRYLNVR
EFVDTAAYARPAPSAAELPQVEASAGDAMVGASSAFNAACHQLSRVARTSATVLFTGESGVGKEKFARMLHKISPRKDRP
FVAVNCAAIPETLIESELFGVERGAYTGASHSRPGRFERASGGTLFLDEIGSLSYVAQGKLLRALQEGEVERVGGTRSIA
VDVRVVAATNEALRQAVLEGKFREDLFFRLNVFPIHLPPLRERRDDIPLLMNHFLNHYRRKHGCNTGGFTQAAVRSLLNY
AFPGNIRELQNLIERAVIMADMEGLIDVHHLFTSGETLSADIMTLRLKGSSATLNFAEPAGCAQALAIATPSSTAQAPQS
LDQTERDTLLRAISTSQGNLSAAARLLNTTRAKLAYRARKHRLL

Sequences:

>Translated_604_residues
MGNTSRISLADVARATGTTLGNFDSALVAKALGGFANAHIGGDAHPNIADISECLFFSPGDGRIWLQDQRMVLLHTEALG
SLRREMIDSLGLEQARGLFTRAGYVSGARDAQLVRRQWPDADPSAIALAGTRLHALEGVVKVEVVRASYKPETGSYEGEF
LWHNSSEDDEHIAAYGIGGSPACWMQVGYATGYVSTLFGHLVVFRETQCRSMGEAHCQVVGKSADQWDDIAQDMRYLNVR
EFVDTAAYARPAPSAAELPQVEASAGDAMVGASSAFNAACHQLSRVARTSATVLFTGESGVGKEKFARMLHKISPRKDRP
FVAVNCAAIPETLIESELFGVERGAYTGASHSRPGRFERASGGTLFLDEIGSLSYVAQGKLLRALQEGEVERVGGTRSIA
VDVRVVAATNEALRQAVLEGKFREDLFFRLNVFPIHLPPLRERRDDIPLLMNHFLNHYRRKHGCNTGGFTQAAVRSLLNY
AFPGNIRELQNLIERAVIMADMEGLIDVHHLFTSGETLSADIMTLRLKGSSATLNFAEPAGCAQALAIATPSSTAQAPQS
LDQTERDTLLRAISTSQGNLSAAARLLNTTRAKLAYRARKHRLL
>Mature_603_residues
GNTSRISLADVARATGTTLGNFDSALVAKALGGFANAHIGGDAHPNIADISECLFFSPGDGRIWLQDQRMVLLHTEALGS
LRREMIDSLGLEQARGLFTRAGYVSGARDAQLVRRQWPDADPSAIALAGTRLHALEGVVKVEVVRASYKPETGSYEGEFL
WHNSSEDDEHIAAYGIGGSPACWMQVGYATGYVSTLFGHLVVFRETQCRSMGEAHCQVVGKSADQWDDIAQDMRYLNVRE
FVDTAAYARPAPSAAELPQVEASAGDAMVGASSAFNAACHQLSRVARTSATVLFTGESGVGKEKFARMLHKISPRKDRPF
VAVNCAAIPETLIESELFGVERGAYTGASHSRPGRFERASGGTLFLDEIGSLSYVAQGKLLRALQEGEVERVGGTRSIAV
DVRVVAATNEALRQAVLEGKFREDLFFRLNVFPIHLPPLRERRDDIPLLMNHFLNHYRRKHGCNTGGFTQAAVRSLLNYA
FPGNIRELQNLIERAVIMADMEGLIDVHHLFTSGETLSADIMTLRLKGSSATLNFAEPAGCAQALAIATPSSTAQAPQSL
DQTERDTLLRAISTSQGNLSAAARLLNTTRAKLAYRARKHRLL

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=305, Percent_Identity=46.8852459016393, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1790437, Length=339, Percent_Identity=43.3628318584071, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI1788550, Length=329, Percent_Identity=41.0334346504559, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1789087, Length=244, Percent_Identity=49.5901639344262, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI87082152, Length=340, Percent_Identity=41.1764705882353, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=42.3076923076923, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789233, Length=295, Percent_Identity=43.0508474576271, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1788905, Length=346, Percent_Identity=36.9942196531792, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87081872, Length=346, Percent_Identity=39.3063583815029, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1786524, Length=263, Percent_Identity=43.7262357414449, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787583, Length=240, Percent_Identity=41.25, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=31.4641744548287, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=37.3949579831933, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 65525; Mature: 65394

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTSRISLADVARATGTTLGNFDSALVAKALGGFANAHIGGDAHPNIADISECLFFSPG
CCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCC
DGRIWLQDQRMVLLHTEALGSLRREMIDSLGLEQARGLFTRAGYVSGARDAQLVRRQWPD
CCEEEEECCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
ADPSAIALAGTRLHALEGVVKVEVVRASYKPETGSYEGEFLWHNSSEDDEHIAAYGIGGS
CCCCEEEEECHHHHHHHCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEECCCC
PACWMQVGYATGYVSTLFGHLVVFRETQCRSMGEAHCQVVGKSADQWDDIAQDMRYLNVR
CHHHEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
EFVDTAAYARPAPSAAELPQVEASAGDAMVGASSAFNAACHQLSRVARTSATVLFTGESG
HHHHHHHHCCCCCCHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCEEEEEECCCC
VGKEKFARMLHKISPRKDRPFVAVNCAAIPETLIESELFGVERGAYTGASHSRPGRFERA
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SGGTLFLDEIGSLSYVAQGKLLRALQEGEVERVGGTRSIAVDVRVVAATNEALRQAVLEG
CCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEECCHHHHHHHHHHC
KFREDLFFRLNVFPIHLPPLRERRDDIPLLMNHFLNHYRRKHGCNTGGFTQAAVRSLLNY
CHHHCEEEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFPGNIRELQNLIERAVIMADMEGLIDVHHLFTSGETLSADIMTLRLKGSSATLNFAEPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCEEECCCCC
GCAQALAIATPSSTAQAPQSLDQTERDTLLRAISTSQGNLSAAARLLNTTRAKLAYRARK
CHHHHHEEECCCCHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HRLL
HCCC
>Mature Secondary Structure 
GNTSRISLADVARATGTTLGNFDSALVAKALGGFANAHIGGDAHPNIADISECLFFSPG
CCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCC
DGRIWLQDQRMVLLHTEALGSLRREMIDSLGLEQARGLFTRAGYVSGARDAQLVRRQWPD
CCEEEEECCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
ADPSAIALAGTRLHALEGVVKVEVVRASYKPETGSYEGEFLWHNSSEDDEHIAAYGIGGS
CCCCEEEEECHHHHHHHCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEECCCC
PACWMQVGYATGYVSTLFGHLVVFRETQCRSMGEAHCQVVGKSADQWDDIAQDMRYLNVR
CHHHEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
EFVDTAAYARPAPSAAELPQVEASAGDAMVGASSAFNAACHQLSRVARTSATVLFTGESG
HHHHHHHHCCCCCCHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCEEEEEECCCC
VGKEKFARMLHKISPRKDRPFVAVNCAAIPETLIESELFGVERGAYTGASHSRPGRFERA
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SGGTLFLDEIGSLSYVAQGKLLRALQEGEVERVGGTRSIAVDVRVVAATNEALRQAVLEG
CCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEECCHHHHHHHHHHC
KFREDLFFRLNVFPIHLPPLRERRDDIPLLMNHFLNHYRRKHGCNTGGFTQAAVRSLLNY
CHHHCEEEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AFPGNIRELQNLIERAVIMADMEGLIDVHHLFTSGETLSADIMTLRLKGSSATLNFAEPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCEEECCCCC
GCAQALAIATPSSTAQAPQSLDQTERDTLLRAISTSQGNLSAAARLLNTTRAKLAYRARK
CHHHHHEEECCCCHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HRLL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]