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The map label for this gene is gsiC [H]

Identifier: 91785972

GI number: 91785972

Start: 61678

End: 62634

Strand: Direct

Name: gsiC [H]

Synonym: Bpro_0059

Alternate gene names: 91785972

Gene position: 61678-62634 (Clockwise)

Preceding gene: 91785971

Following gene: 91785973

Centisome position: 1.19

GC content: 64.26

Gene sequence:

>957_bases
ATGAACCTGCAACTCCTGCGCCTTATCGCGGGCCGGCTGGCCGTGGGGGTGGTTTCACTCCTTATTGTGTCGGCCGTTGT
GTTTGCGATCACGGGCTTGTTGCCTGGCGACGCGGCGCAGGAGCAGCTGGGCCAGGAGGCGACGCCTGAAGCCCTGGCTG
CGCTGCGCCAGCAGATGGGCCTCACGCAGTCCGGCCCGGAACGTTACTGGCAGTGGCTGAACGGCTTGCTGCGCGGCAAC
CCCGGCCAGTCGATTGTCAGCAGCGCACCGGTCGCCGACCTGATCGGCAGCCGGCTGCCCAACTCGCTGATGCTGGCCGG
CGTGACCGCGCTGGTGTCGGTGCCGCTGGCGCTGCTGCTGGGCATTTTGTCGGCGGTCTGGCGCGGCTCCTGGTTTGACC
GCGCTGCCAGCATGGGCGCGGTGGCCGTGGTCTCGGTGCCCGAATTTTTGGTTGCCACACTCGCGGTGCTGGTGTTTGCG
GTGCATTTGCGCTGGCTGCCGGCGCTGTCTTATTCGGTGGACATCTCGTCGCCGGGCCAGATGCTGCGCTCGTTTGCGAT
GCCGGTCATGAGCCTGTCCTGCGTGATCATTGCGCAGATGATGCGCATGACACGCGCTGCGGTGATTGACCAGCTGCGCG
CGCCGTATATCGAGATGGTCAAGCTCAAGGGCGCTTCGCCTGCGCGCATGGTGCTGGCGCATGCCTTGCCCAACGCGATC
GGCCCGATAGCCAATGCGGTGGCGCTGAGCCTGTCGTATTTGCTGGGTGGCGTGATCATTATCGAAACCATTTTTAACTA
CCCCGGCATCGCCAAACTCATGGTCGATGGCGTGAGCCAGCGCGACATGCCGCTGGTGCAAGCCTGCGCGATGATTTTTT
GCGCTGCTTACCTGATTCTTGTGACGCTGGCCGACCTCTGCGGCATCGTCGCCAACCCAAGGCTGCGCCACCAATGA

Upstream 100 bases:

>100_bases
GAAGGGGAGGTAGCATGAGTCCCCACGCTCGGCACTGCGTGTCTTCGCTGCTCACCGAGGTGGCATGCCCCGCTTGGGGT
GGCCCGGCGCGAGGCATGGC

Downstream 100 bases:

>100_bases
GCTCCGCTATTGAAACAATTCCGCCCGCCGCCGTTCCGGCGCGCCTGGTGCCGCGCCTGTCGCGCTGGTCGCGCACCGGC
CTGCTGGGCCTGGCGGTGCT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNLQLLRLIAGRLAVGVVSLLIVSAVVFAITGLLPGDAAQEQLGQEATPEALAALRQQMGLTQSGPERYWQWLNGLLRGN
PGQSIVSSAPVADLIGSRLPNSLMLAGVTALVSVPLALLLGILSAVWRGSWFDRAASMGAVAVVSVPEFLVATLAVLVFA
VHLRWLPALSYSVDISSPGQMLRSFAMPVMSLSCVIIAQMMRMTRAAVIDQLRAPYIEMVKLKGASPARMVLAHALPNAI
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVSQRDMPLVQACAMIFCAAYLILVTLADLCGIVANPRLRHQ

Sequences:

>Translated_318_residues
MNLQLLRLIAGRLAVGVVSLLIVSAVVFAITGLLPGDAAQEQLGQEATPEALAALRQQMGLTQSGPERYWQWLNGLLRGN
PGQSIVSSAPVADLIGSRLPNSLMLAGVTALVSVPLALLLGILSAVWRGSWFDRAASMGAVAVVSVPEFLVATLAVLVFA
VHLRWLPALSYSVDISSPGQMLRSFAMPVMSLSCVIIAQMMRMTRAAVIDQLRAPYIEMVKLKGASPARMVLAHALPNAI
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVSQRDMPLVQACAMIFCAAYLILVTLADLCGIVANPRLRHQ
>Mature_318_residues
MNLQLLRLIAGRLAVGVVSLLIVSAVVFAITGLLPGDAAQEQLGQEATPEALAALRQQMGLTQSGPERYWQWLNGLLRGN
PGQSIVSSAPVADLIGSRLPNSLMLAGVTALVSVPLALLLGILSAVWRGSWFDRAASMGAVAVVSVPEFLVATLAVLVFA
VHLRWLPALSYSVDISSPGQMLRSFAMPVMSLSCVIIAQMMRMTRAAVIDQLRAPYIEMVKLKGASPARMVLAHALPNAI
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVSQRDMPLVQACAMIFCAAYLILVTLADLCGIVANPRLRHQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=314, Percent_Identity=34.0764331210191, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=28.4023668639053, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789888, Length=317, Percent_Identity=29.9684542586751, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=27.7070063694268, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787761, Length=295, Percent_Identity=29.1525423728814, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788504, Length=324, Percent_Identity=25.3086419753086, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787550, Length=275, Percent_Identity=25.8181818181818, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33729; Mature: 33729

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQLLRLIAGRLAVGVVSLLIVSAVVFAITGLLPGDAAQEQLGQEATPEALAALRQQMG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHC
LTQSGPERYWQWLNGLLRGNPGQSIVSSAPVADLIGSRLPNSLMLAGVTALVSVPLALLL
CCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GILSAVWRGSWFDRAASMGAVAVVSVPEFLVATLAVLVFAVHLRWLPALSYSVDISSPGQ
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCHHH
MLRSFAMPVMSLSCVIIAQMMRMTRAAVIDQLRAPYIEMVKLKGASPARMVLAHALPNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVSQRDMPLVQACAMIFCAAYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VTLADLCGIVANPRLRHQ
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNLQLLRLIAGRLAVGVVSLLIVSAVVFAITGLLPGDAAQEQLGQEATPEALAALRQQMG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHC
LTQSGPERYWQWLNGLLRGNPGQSIVSSAPVADLIGSRLPNSLMLAGVTALVSVPLALLL
CCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GILSAVWRGSWFDRAASMGAVAVVSVPEFLVATLAVLVFAVHLRWLPALSYSVDISSPGQ
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCHHH
MLRSFAMPVMSLSCVIIAQMMRMTRAAVIDQLRAPYIEMVKLKGASPARMVLAHALPNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
GPIANAVALSLSYLLGGVIIIETIFNYPGIAKLMVDGVSQRDMPLVQACAMIFCAAYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VTLADLCGIVANPRLRHQ
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]