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The map label for this gene is uxuR [H]

Identifier: 91213968

GI number: 91213968

Start: 4918126

End: 4918899

Strand: Direct

Name: uxuR [H]

Synonym: UTI89_C5020

Alternate gene names: 91213968

Gene position: 4918126-4918899 (Clockwise)

Preceding gene: 91213967

Following gene: 91213969

Centisome position: 97.09

GC content: 54.13

Gene sequence:

>774_bases
ATGAAATCTGCCACCTCTGCGCAAAGACCTTACCAGGAAGTCGGGGCGATGATCCGCGATCTGATCATAAAGACGCCGTA
CAATCCTGGCGAACGGCTGCCACCGGAGCGTGAAATTGCAGAAATGCTTGATGTCACGCGGACGGTGGTACGTGAAGCGC
TGATCATGCTGGAGATCAAAGGGCTGGTGGAAGTGCGTCGGGGTGCAGGTATCTATGTTCTTGATAGCTCAGGCAGCCAC
AACGCAGACAGTCCGGATGCCAACGTCTGCAACGATGCCGGTCCTTTTGAGCTGTTACAGGCGCGGCAGTTACTGGAAAG
TAACATCGCCGAGTTTGCCGCCCTGCAGGCTACCCGCGAAGATATCGTCAAAATGCGCAAGGCATTGCAACTGGAAGAGC
GTGAACTGGCTTCCAGCGCGCCGGGCAGCAGCGAAAGCGGTGACATGCAGTTCCATCTCGCCATTGCCGAAGCAACGCAT
AACAGCATGCTGGTGGAGTTATTCCGTCAGTCCTGGCAGTGGCGGGAAAACAATCCAATGTGGATCCAGTTGCACAGCCA
TCTGGATGACAGCCTGTATCGCAAAGAGTGGTTGGGCGATCACAAACAGATCCTCGCCGCGTTAATCAAAAAAGATGCCC
GAGCGGCGAAGCTGGCAATGTGGCAGCATCTGGAGAATGTGAAGCAGCGCTTGCTGGAGTTCTCTAATGTTGATGACATC
TATTTCGATGGCTATCTGTTTGATTCATGGCCGCTGGATAAAGTCGACGCCTGA

Upstream 100 bases:

>100_bases
GCTTAACGGGTGCCGTAAAATTGCCCGTTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGGAAAAAATTTGATTAACCG
CACCTAACGGACACAACACC

Downstream 100 bases:

>100_bases
TCCCTCATTTCTGGTGCAAAGTTGAACCGCTTTGCACTATGTATGTTCCCTGAATAGTTAATTATGTTCTGCAGAATATA
TTATGCGTAATTTAATCATT

Product: DNA-binding transcriptional repressor UxuR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSH
NADSPDANVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRKALQLEERELASSAPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDA

Sequences:

>Translated_257_residues
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSH
NADSPDANVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRKALQLEERELASSAPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDA
>Mature_257_residues
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSH
NADSPDANVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRKALQLEERELASSAPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDA

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=257, Percent_Identity=98.443579766537, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI87082208, Length=255, Percent_Identity=46.2745098039216, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786303, Length=228, Percent_Identity=32.8947368421053, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790032, Length=232, Percent_Identity=29.7413793103448, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789353, Length=257, Percent_Identity=27.6264591439689, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI48994955, Length=234, Percent_Identity=26.0683760683761, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789621, Length=224, Percent_Identity=29.4642857142857, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29261; Mature: 29261

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSSGSHNADSPDANVCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVKMRKALQLEERELASSAPGSSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFDSWPLDKVDA
EECCEEECCCCCCCCCC
>Mature Secondary Structure
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSSGSHNADSPDANVCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVKMRKALQLEERELASSAPGSSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFDSWPLDKVDA
EECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]