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The map label for this gene is yjcC [H]

Identifier: 91213600

GI number: 91213600

Start: 4544234

End: 4545829

Strand: Direct

Name: yjcC [H]

Synonym: UTI89_C4647

Alternate gene names: 91213600

Gene position: 4544234-4545829 (Clockwise)

Preceding gene: 162138311

Following gene: 91213602

Centisome position: 89.71

GC content: 44.67

Gene sequence:

>1596_bases
TTGATAGCAATGAGTCATCGTGCACGACACCAATTACTGGCGTTTCCGGGCATTATCTTTTTAGTTCTCTTTCCCATCAT
TCTGTCGCTATGGATTGCCTTCTTTTGGGCAAAATCAGAAGTGAATAATCAGCTCCGAACCTTTGCTCAGCTGGCGTTGG
ATAAATCTGAGCTGGTCATTCGTCAGGCAGATTTAGTGAGCGATGCAGCTGAACGCTATCAGGGGCAAGTTTGCACTCCA
GCCCATCAAAAGCGAATGTTGAATATTATTCGTGGCTATCTTTATATTAATGAATTGATTTATGCTCGTGATAACCATTT
TTTATGCTCATCGCTGATAGCGTCTGTAAATGGCTATACGATTGCACCGGCCGATTATAAGCGCGAACCTAACGTTTCTA
TCTATTATTACCGTGATACGCCTTTTTTCTCTGGCTATAAAATGACCTACATGCAGCGGGGAAATTATGTGGCGGTTATC
AACCCTCTCTTCTGGAGTGAAGTGATGTCTGATGATCCGACATTGCAATGGGGAGTGTATGATACGGTGACGAAAACCTT
TTTCTCGTTAAGCAACGAGGCCTCGGCAGCAACGTTTTCTCCGCTGATTCATTTGAATGATTTAACCGTACAACGAAATG
GCTATTTATATGCGACAGTTTATTCGACAAAACGCCCAATTGCAGCCATTGTTGCGACTTCATATCAACGTCTTATAACT
CATTTTTATAATCATCTTATTTTTGCGTTGCCCGCCGGTATTTTGGGGAGTCTTGTTCTGCTATTACTCTGGCTACGTAT
TCGACAAAACTATTTGTCTCCCAAACGCAAATTGCAACGCGCCCTCGAAAAACATCAACTTTGCCTTTATTACCAGCCAA
TAATCGATATCAAAACAGAAAAATGTATCGGCGCTGAAGCGTTGTTACGTTGGCCTGGTGAGCAGGGGCAAGTAATGAAT
CCGGCAGAGTTTATTCCGCTGGCAGAAAAGGAGGGGATGATCGAACAGGTAACTGATTATGTTATTGATAATGTCTTCCG
TGATTTGGGCGCGTATCTGGCAACACATACCGATCGCTATGTTTCTATTAACCTGTCAGCCTCCGATTTTCATACCTCAC
GGTTGATAGCGCGAACCAATCAGAAAACAGAGCAACATGCGGTGCGTCCGCAGCAAATTAAATTTGAAGTGACTGAACAT
GCATTTCTTGATGTCGACAAAATGACGCCGATTATTCTGGCTTTCCGCAAGGCCGGTTACGAAGTGGCAATTGATGATTT
TGGTATTGGCTACTCTAACTTGCATAACCTTAAATCATTGAATGTCGATATTTTGAAAATCGATAAATCGTTTGTTGAGA
CGCTGACCACCCACAAAACCAGTCATTTGATTGCGGAACACATCATCGAGCTGGCGCACAGCCTGGGGTTAAAAACGATC
GCTGAAGGTGTCGAAACTGAGGCGCAGGTTAACTGGCTGCGCAAACGCGGCGTGCGCTATTGCCAGGGATGGTTCTTCGC
GAAGGCGATGCCGCCGCAGGTGTTTATGCAATGGATGGAGCAATTACCCGCGCGGGAGTTAACGCGCGGGCAATAA

Upstream 100 bases:

>100_bases
TTATATCAGGCAAAAGTGCTATTTATACCGTAAGATTTATCTAAAGACGTCGGTAGCCAGGGTTTCACCTTGCAATAACC
GGGTATAAACAGGCAGGGAA

Downstream 100 bases:

>100_bases
AACTACAGGCGGTGGCGATAATCGCTGGGAGTGCGATCAAACTGCCGACGGAAAACGCGGGAGAAGGTCTGCTGAGAGAC
ATAACCCAGGTCCATTGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MIAMSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTP
AHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVI
NPLFWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIT
HFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMN
PAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEH
AFLDVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTI
AEGVETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Sequences:

>Translated_531_residues
MIAMSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTP
AHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVI
NPLFWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIT
HFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMN
PAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEH
AFLDVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTI
AEGVETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
>Mature_531_residues
MIAMSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTP
AHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVI
NPLFWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIT
HFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMN
PAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEH
AFLDVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTI
AEGVETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=97.5378787878788, Blast_Score=1052, Evalue=0.0,
Organism=Escherichia coli, GI87081743, Length=528, Percent_Identity=33.3333333333333, Blast_Score=295, Evalue=7e-81,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=34.7490347490347, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI226510982, Length=251, Percent_Identity=38.2470119521912, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788502, Length=286, Percent_Identity=29.020979020979, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081845, Length=279, Percent_Identity=31.5412186379928, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081921, Length=244, Percent_Identity=36.0655737704918, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1787541, Length=249, Percent_Identity=32.1285140562249, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=30.0847457627119, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=30.5785123966942, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=31.1023622047244, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=30.6382978723404, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787410, Length=225, Percent_Identity=27.5555555555556, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 61009; Mature: 61009

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAMSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
RQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYT
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCE
IAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVY
ECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCEEECHH
DTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIT
HHHHHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHH
HFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCC
KCIGAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRY
HHCCHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFLDVDKMTPIILAFRKAGY
EEEEECCCHHHHHHHHHHCCCCHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCC
EVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTI
EEEEECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AEGVETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
HHCCCHHHHHHHHHHCCHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MIAMSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
RQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYT
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCE
IAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVY
ECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCEEECHH
DTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIT
HHHHHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHH
HFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCC
KCIGAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRY
HHCCHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFLDVDKMTPIILAFRKAGY
EEEEECCCHHHHHHHHHHCCCCHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCC
EVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTI
EEEEECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AEGVETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
HHCCCHHHHHHHHHHCCHHHHHCCHHHCCCCHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]