Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 91213563

GI number: 91213563

Start: 4501937

End: 4502809

Strand: Direct

Name: ubiA [H]

Synonym: UTI89_C4610

Alternate gene names: 91213563

Gene position: 4501937-4502809 (Clockwise)

Preceding gene: 91213562

Following gene: 91213565

Centisome position: 88.87

GC content: 51.43

Gene sequence:

>873_bases
ATGGAGTGGAGTCTGACGCAGAATAAGCTGCTGGCGTTTCATCGCTTAATGCGTACGGATAAGCCAATTGGCGCGTTACT
GCTGCTCTGGCCAACATTATGGGCGTTGTGGGTGGCGACACCGGGCGTTCCCCAGCTCTGGATCCTGGCGGTGTTTGTCG
CGGGCGTCTGGCTGATGCGCGCTGCTGGTTGTGTGGTGAATGATTATGCTGACCGCAAGTTTGATGGTCATGTTAAGCGC
ACGGCGAACCGACCACTTCCCAGCGGCGCGGTAACGGAGAAAGAGGCGCGCGCGCTGTTTGTAGTGCTGGTACTGATTTC
ATTTTTACTGGTGCTGACGCTGAATACGATGACTATTCTGTTGTCGATTGCCGCGCTGGCGCTGGCGTGGGTATACCCGT
TTATGAAGCGGTATACCCATCTACCGCAAGTGGTGCTGGGCGCGGCGTTTGGCTGGTCGATTCCAATGGCTTTTGCCGCT
GTGAGTGAGTCGGTGCCATTGAGTTGCTGGTTAATGTTCCTCGCCAATATTCTCTGGGCGGTGGCTTACGACACGCAGTA
TGCGATGGTTGACCGCGATGATGATGTGAAGATTGGCATTAAATCCACCGCAATCCTGTTCGGCCAATACGATAAATTGA
TTATTGGTATTTTTCAGATTGGCGTACTAGCGCTGATGGCGATCATCGGTGAGTTAAATGGCTTAGGCTGGGGATATTAC
TGGTCAATTCTGGTAGCTGGCGCGCTGTTTGTTTATCAACAAAAACTGATTGCCAACCGCGAGCGTGAAGCCTGCTTTAA
AGCATTTATGAATAATAACTATGTTGGTCTGGTACTGTTTTTAGGGCTGGCAATGAGTTACTGGCATTTCTGA

Upstream 100 bases:

>100_bases
ACTGTGGGGGCGACGTTCCCGCCTGCGATTAAGCGGTAAACCGCTGTTGCTAACAGAACTGTTTTTACCGGCGTCACCGT
TGTACTAAGAGGAAAAAAAT

Downstream 100 bases:

>100_bases
TGATGTAAAAAAGCCGGATGATCATCCGGCTTTCTTCTGGGTTGCCTGATGCGCTGCGCTTCTCAGGCCTACAACATATC
GCAATTTATTGAATTTGCAG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYY
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF

Sequences:

>Translated_290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYY
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
>Mature_290_residues
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYY
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=282, Percent_Identity=34.7517730496454, Blast_Score=177, Evalue=9e-45,
Organism=Escherichia coli, GI1790473, Length=290, Percent_Identity=99.6551724137931, Blast_Score=583, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=37.3665480427046, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=37.3239436619718, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17553720, Length=183, Percent_Identity=42.0765027322404, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=44.6808510638298, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=44.2857142857143, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=300, Percent_Identity=32, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=37.6811594202899, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32546; Mature: 32546

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTIL
HCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYY
HHHCCEEEEECCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMR
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTIL
HCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIFQIGVLALMAIIGELNGLGWGYY
HHHCCEEEEECCCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA