| Definition | Escherichia coli UTI89 chromosome, complete genome. |
|---|---|
| Accession | NC_007946 |
| Length | 5,065,741 |
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The map label for this gene is aceB [H]
Identifier: 91213526
GI number: 91213526
Start: 4463686
End: 4465305
Strand: Direct
Name: aceB [H]
Synonym: UTI89_C4573
Alternate gene names: 91213526
Gene position: 4463686-4465305 (Clockwise)
Preceding gene: 91213525
Following gene: 91213527
Centisome position: 88.12
GC content: 51.17
Gene sequence:
>1620_bases ATGACGAGGAGCTGCACGATGACTGAACAGGCAACAACAATCGATGAACTGGCTTTTACAAGGCCGTATGGCGAGCAGGA GAAGCAAATTCTTACTGCCGAAGCGGTAGAATTTCTGACTGAGCTGGTGACGCATTTTACGCCACAACGCAATAAACTTC TGGCAGCGCGTATTCAGCAGCAGCAGGATATCGATAACGGAATGTTGCCTGATTTTATTTCGGAAACAGCTTCCATTCGT GATGCTGACTGGAAAATTCGCGGGATTCCTTCGGACTTAGAAGATCGTCGCGTAGAGATTACCGGACCTGTAGAGCGCAA GATGGTGATCAACGCGCTCAACGCCAATGTGAAAGTCTTTATGGCCGATTTCGAAGATTCACTGGCACCAGACTGGAACA AAGTGATCGATGGGCAAATTAACCTGCGCGATGCGGTTAACGGCACCATCAGCTATAGCAATGAAGCAGGCAAAATTTAT CAGCTCAAGCCCAATCCAGCGGTTTTGATTTGTCGGGTACGCGGTCTGCACTTGCCGGAAAAACATGTCACCTGGCGTGG TGAGACAATCCCCGGTAGCCTGTTTGATTTTGCGCTCTATTTCTTCCACAACTATCAGGCACTGTTGGCAAAGGGCAGCG GTCCCTATTTCTATCTGCCGAAAACCCAGTCCTGGCAGGAAGCGGCCTGGTGGAGCGAAGTCTTCAGCTATGCAGAAGAT CGCTTTAATCTGCCGCGCGGCACCATCAAGGCGACGTTGCTGATTGAAACGCTGCCCGCCGTGTTCCAGATGGATGAAAT CCTTCACGCGCTGCGTGACCATATTGTTGGTCTGAACTGCGGTCGTTGGGATTACATCTTCAGTTATATCAAAACATTGA AAAACTATCCCGATCGCGTCCTGCCAGACAGACAGGCAGTGACGATGGATAAACCCTTCCTGAATGCTTACTCACGCCTG TTGATTAAAACCTGCCATAAACGCGGTGCTTTTGCGATGGGCGGCATGGCGGCGTTTATTCCAAGCAAAGATGAAGAGCG CAATAACCAGGTGCTCGACAAAGTAAAAGCGGATAAATCGCTGGAAGCCAATAACGGTCACGATGGCACATGGATCGCTC ACCCGGGCCTTGCTGATACGGCAATGGCGGTATTCAACGATATTCTCGGCTCCCGCAAAAACCAGCTTGAGGTGATGCGC GAACAAGACGCGCCGATTACTGCCGATCAGCTGCTGGCACCTTGTGATGGTGAACGCACCGAAGAAGGTATGCGCGCCAA CATTCGCGTGGCTGTGCAGTACATCGAAGCGTGGATCTCTGGCAATGGCTGTGTGCCGATTTATGGCCTGATGGAAGATG CGGCGACGGCTGAAATTTCCCGTACCTCAATCTGGCAGTGGATCCATCATCAAAAAACGTTGAGCAATGGCAAACCGGTG ACTAAAGCCTTGTTCCGCCAGATGCTGGGCGAAGAGATGAAAGTCATTGCCAGCGAACTGGGCGAAGAACGTTTCTCCCA TGGGCGTTTTGACGATGCCGCACGCTTGATGGAACAGATCACCACTTCCGATGAGTTAATTGATTTCCTGACCCTGCCAG GCTACCGCCTGTTAGCGTAA
Upstream 100 bases:
>100_bases AAATTGTTTTTGATTTTGCATTTTAAATGAGTAGTCTTAGTTGTGCTGAACGAAAAGCGCACAACGATCCTTCGTTCACA GTGGGGAAGTTTTCGGATCC
Downstream 100 bases:
>100_bases ACCACCACATAACTATGGAGCATCTGCACATGAAAACCCGTACACAACAAATTGAAGAATTACAGAAAGAGTGGACTCAA CCGCGTTGGGAAGGCATTAC
Product: malate synthase
Products: NA
Alternate protein names: MSA [H]
Number of amino acids: Translated: 539; Mature: 538
Protein sequence:
>539_residues MTRSCTMTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGMLPDFISETASIR DADWKIRGIPSDLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIY QLKPNPAVLICRVRGLHLPEKHVTWRGETIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAED RFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRL LIKTCHKRGAFAMGGMAAFIPSKDEERNNQVLDKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMR EQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPV TKALFRQMLGEEMKVIASELGEERFSHGRFDDAARLMEQITTSDELIDFLTLPGYRLLA
Sequences:
>Translated_539_residues MTRSCTMTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGMLPDFISETASIR DADWKIRGIPSDLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIY QLKPNPAVLICRVRGLHLPEKHVTWRGETIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAED RFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRL LIKTCHKRGAFAMGGMAAFIPSKDEERNNQVLDKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMR EQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPV TKALFRQMLGEEMKVIASELGEERFSHGRFDDAARLMEQITTSDELIDFLTLPGYRLLA >Mature_538_residues TRSCTMTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGMLPDFISETASIRD ADWKIRGIPSDLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIYQ LKPNPAVLICRVRGLHLPEKHVTWRGETIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDR FNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLL IKTCHKRGAFAMGGMAAFIPSKDEERNNQVLDKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMRE QDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPVT KALFRQMLGEEMKVIASELGEERFSHGRFDDAARLMEQITTSDELIDFLTLPGYRLLA
Specific function: Glyoxylate bypass; second step. [C]
COG id: COG2225
COG function: function code C; Malate synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the malate synthase family [H]
Homologues:
Organism=Escherichia coli, GI1790444, Length=533, Percent_Identity=98.4990619136961, Blast_Score=1097, Evalue=0.0, Organism=Caenorhabditis elegans, GI17561814, Length=516, Percent_Identity=50.968992248062, Blast_Score=508, Evalue=1e-144, Organism=Caenorhabditis elegans, GI71982926, Length=410, Percent_Identity=53.6585365853659, Blast_Score=421, Evalue=1e-118, Organism=Saccharomyces cerevisiae, GI6324212, Length=529, Percent_Identity=45.7466918714556, Blast_Score=440, Evalue=1e-124, Organism=Saccharomyces cerevisiae, GI6322222, Length=530, Percent_Identity=46.0377358490566, Blast_Score=437, Evalue=1e-123,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011076 - InterPro: IPR006252 - InterPro: IPR001465 - InterPro: IPR019830 [H]
Pfam domain/function: PF01274 Malate_synthase [H]
EC number: =2.3.3.9 [H]
Molecular weight: Translated: 61057; Mature: 60926
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: PS00510 MALATE_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTRSCTMTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQ CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH QQDIDNGMLPDFISETASIRDADWKIRGIPSDLEDRRVEITGPVERKMVINALNANVKVF HHCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEE MADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIYQLKPNPAVLICRVRGLHLPE EECCCCCCCCCHHHHCCCCEEEHHHCCCEEEECCCCCEEEEECCCCEEEEEEECCCCCCC KHVTWRGETIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAED HHCCCCCCCCCCHHHHHHHHHHHCCHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHH RFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRV HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHC LPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFIPSKDEERNNQVLDKVKADKS CCCCCEEECCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHHCCCC LEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPITADQLLAPCDGERT CCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCC EEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPV CCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH TKALFRQMLGEEMKVIASELGEERFSHGRFDDAARLMEQITTSDELIDFLTLPGYRLLA HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCC >Mature Secondary Structure TRSCTMTEQATTIDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQ CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH QQDIDNGMLPDFISETASIRDADWKIRGIPSDLEDRRVEITGPVERKMVINALNANVKVF HHCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEE MADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIYQLKPNPAVLICRVRGLHLPE EECCCCCCCCCHHHHCCCCEEEHHHCCCEEEECCCCCEEEEECCCCEEEEEEECCCCCCC KHVTWRGETIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAED HHCCCCCCCCCCHHHHHHHHHHHCCHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHH RFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRV HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHC LPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFIPSKDEERNNQVLDKVKADKS CCCCCEEECCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHHCCCC LEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPITADQLLAPCDGERT CCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCC EEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPV CCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH TKALFRQMLGEEMKVIASELGEERFSHGRFDDAARLMEQITTSDELIDFLTLPGYRLLA HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 3050899; 3060852; 8265357; 9278503 [H]