Click here to switch to the map view.

The map label for this gene is ptsG [H]

Identifier: 91213361

GI number: 91213361

Start: 4283149

End: 4284657

Strand: Direct

Name: ptsG [H]

Synonym: UTI89_C4399

Alternate gene names: 91213361

Gene position: 4283149-4284657 (Clockwise)

Preceding gene: 91213360

Following gene: 91213362

Centisome position: 84.55

GC content: 49.37

Gene sequence:

>1509_bases
ATGAGCAAAAAAATAACATCCTTGTTTAACTTCAAGAAGTTGCAGAAATTTTCTTCTGCTCTGATGTTACCAATCGCCAT
TCTTCCGGCGGCGGGTTTGATTTTAGCCATCGGGATTTCATTTAACATTGAGCTGCTGGCGAATTGCGGCGGCCTGATTT
TCGCCAACCTTCCTTTGCTGTTTTGTGTCGGTATTGTGATTGGCCTGACAGGTGATGGTTCTTCATCACTTTCAGCGATT
ATCAGCTACATGATCATGAATGCCACGATGGGAACGCAACTTGGCATTACCGCGGAGTCCGTTGCAGCCAGTAACGGTGA
CTATGCGATGATCCTCGGGGTACCGACGTTACAAACGGGAGTGTTTGGCGGTTTGATTGTCGCCATCTTTGTTTATCTGC
TCTATACCCGCTTCCACAATATTGAATTGCCTCAGTTTCTTGGTTTCTTCGGTGGAAAACGCTTTGTACCGATTATTACG
GCGGTGGCGGCAATTATTGTCGGCTATTTATTGCCGTGGCTGTGGATACCGGTACAAAAAGGTCTGGCGTCGCTTTCAAC
GCTGGTGACCAGTGGGCATAACGCGAACTTCGCGGCCTTTATTTACGCCGTTGGCGAACGTTCGCTGATTCCTTTTGGCC
TGCATCATATCTGGAACGTGCCGTTTTATTACAACTTTGGCGACTACATGACCAAATCCGGGCAACTGGTGACGGGCGAT
ATTCCGGTGTTCTTTGCCCAATTGCGCGACGGTGTTCCGTTGACGGCGGGGTTGTTTATGACAGGTCGTTTCCCAATCAT
GATGTTTGCGTTACCTGCCGCCGCGTTGGCGATGTATCAGGAAGCAAAACCGGAACGTAAGGCGCTGATTAAAGGCCTTT
TACTCTCCGGTGCGCTGACCACATTTGTTACCGGGATTACGGAGCCGCTGGAATATGCATTTTTGTTTGCAGCTCCGGTT
CTCTACATCATTCACATCTTCTTATATGCCACTTCATTTGTGCTGATGAACATCCTGAATGTGCACATTGGTCATCCTTT
TGCTGGCGGTCTTATTGATTTCGTACTGAATGGCGTTATGCCAAACCGCACGCCGTGGTATCTGGTGTTCCTGGCAGGCG
CGGGCTATGCAGCGATTTACTACACCGTATTTCGGGTACTGATCCGCAAGTTGAATCTGAAAACACCGGGACGTGAGGAT
GAAGAGATTGCCGTTGCAACCACATTAACGCGCGAAGAACGTCCATACCAAATCATCGAGGCAGTAGGTGGTTTCGACAA
TATCGAAGATGTGGATGCCTGCGCAACACGCCTGAGGCTGGCGCTGGTAGACGATAAGAAAGTGAATGAAAAACGGCTGA
AGGAGTTGGGGGCTGCGGGTTTAGTGAAACTGGGTGATGGCGGTGTACAGGTGATATTTGGCGGCAAATCGCAAATCCTG
CGCGACGAAATCAAAACCGTAATGAGCAGACCGCGCCCGACAGAAATGACAGTGGCCTGTGCTAACTAA

Upstream 100 bases:

>100_bases
CTGCTGAAAGCGGTGCGCCGGAAAGTGAACTGTTTAAGCGCCACGCCAATCTGGAATAGTCGTCGCCGTTATTTGCTCGA
TACCCTACAGGAGAATAAAA

Downstream 100 bases:

>100_bases
TTCGAGATTAGCGGGCTGGTTTCAGCCCGCCAGACAGAGAGAGCTGAAGTATGAATTCACAATTACTGGCTAACGCCATC
CGAATGTTAAGTGTTGATGC

Product: PTS system glucose-specific transporter subunit IIBC

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIELLANCGGLIFANLPLLFCVGIVIGLTGDGSSSLSAI
ISYMIMNATMGTQLGITAESVAASNGDYAMILGVPTLQTGVFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIIT
AVAAIIVGYLLPWLWIPVQKGLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIWNVPFYYNFGDYMTKSGQLVTGD
IPVFFAQLRDGVPLTAGLFMTGRFPIMMFALPAAALAMYQEAKPERKALIKGLLLSGALTTFVTGITEPLEYAFLFAAPV
LYIIHIFLYATSFVLMNILNVHIGHPFAGGLIDFVLNGVMPNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLNLKTPGRED
EEIAVATTLTREERPYQIIEAVGGFDNIEDVDACATRLRLALVDDKKVNEKRLKELGAAGLVKLGDGGVQVIFGGKSQIL
RDEIKTVMSRPRPTEMTVACAN

Sequences:

>Translated_502_residues
MSKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIELLANCGGLIFANLPLLFCVGIVIGLTGDGSSSLSAI
ISYMIMNATMGTQLGITAESVAASNGDYAMILGVPTLQTGVFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIIT
AVAAIIVGYLLPWLWIPVQKGLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIWNVPFYYNFGDYMTKSGQLVTGD
IPVFFAQLRDGVPLTAGLFMTGRFPIMMFALPAAALAMYQEAKPERKALIKGLLLSGALTTFVTGITEPLEYAFLFAAPV
LYIIHIFLYATSFVLMNILNVHIGHPFAGGLIDFVLNGVMPNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLNLKTPGRED
EEIAVATTLTREERPYQIIEAVGGFDNIEDVDACATRLRLALVDDKKVNEKRLKELGAAGLVKLGDGGVQVIFGGKSQIL
RDEIKTVMSRPRPTEMTVACAN
>Mature_501_residues
SKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIELLANCGGLIFANLPLLFCVGIVIGLTGDGSSSLSAII
SYMIMNATMGTQLGITAESVAASNGDYAMILGVPTLQTGVFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIITA
VAAIIVGYLLPWLWIPVQKGLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIWNVPFYYNFGDYMTKSGQLVTGDI
PVFFAQLRDGVPLTAGLFMTGRFPIMMFALPAAALAMYQEAKPERKALIKGLLLSGALTTFVTGITEPLEYAFLFAAPVL
YIIHIFLYATSFVLMNILNVHIGHPFAGGLIDFVLNGVMPNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLNLKTPGREDE
EIAVATTLTREERPYQIIEAVGGFDNIEDVDACATRLRLALVDDKKVNEKRLKELGAAGLVKLGDGGVQVIFGGKSQILR
DEIKTVMSRPRPTEMTVACAN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=489, Percent_Identity=44.1717791411043, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1787908, Length=514, Percent_Identity=37.5486381322957, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1786894, Length=490, Percent_Identity=38.3673469387755, Blast_Score=299, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 54521; Mature: 54390

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIELLANCGGLIFANLPLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHH
FCVGIVIGLTGDGSSSLSAIISYMIMNATMGTQLGITAESVAASNGDYAMILGVPTLQTG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCHHHHH
VFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIITAVAAIIVGYLLPWLWIPVQK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIWNVPFYYNFGDYMTKSGQLVTGD
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCCEEECCHHHHCCCCCEEECC
IPVFFAQLRDGVPLTAGLFMTGRFPIMMFALPAAALAMYQEAKPERKALIKGLLLSGALT
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TFVTGITEPLEYAFLFAAPVLYIIHIFLYATSFVLMNILNVHIGHPFAGGLIDFVLNGVM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLNLKTPGREDEEIAVATTLTREERPYQIIE
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHH
AVGGFDNIEDVDACATRLRLALVDDKKVNEKRLKELGAAGLVKLGDGGVQVIFGGKSQIL
HHCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCEEEECCCCEEEEECCCHHHH
RDEIKTVMSRPRPTEMTVACAN
HHHHHHHHCCCCCCCEEEEECC
>Mature Secondary Structure 
SKKITSLFNFKKLQKFSSALMLPIAILPAAGLILAIGISFNIELLANCGGLIFANLPLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHH
FCVGIVIGLTGDGSSSLSAIISYMIMNATMGTQLGITAESVAASNGDYAMILGVPTLQTG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEECCHHHHH
VFGGLIVAIFVYLLYTRFHNIELPQFLGFFGGKRFVPIITAVAAIIVGYLLPWLWIPVQK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLASLSTLVTSGHNANFAAFIYAVGERSLIPFGLHHIWNVPFYYNFGDYMTKSGQLVTGD
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHCCCEEECCHHHHCCCCCEEECC
IPVFFAQLRDGVPLTAGLFMTGRFPIMMFALPAAALAMYQEAKPERKALIKGLLLSGALT
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TFVTGITEPLEYAFLFAAPVLYIIHIFLYATSFVLMNILNVHIGHPFAGGLIDFVLNGVM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
PNRTPWYLVFLAGAGYAAIYYTVFRVLIRKLNLKTPGREDEEIAVATTLTREERPYQIIE
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHH
AVGGFDNIEDVDACATRLRLALVDDKKVNEKRLKELGAAGLVKLGDGGVQVIFGGKSQIL
HHCCCCCCHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCEEEECCCCEEEEECCCHHHH
RDEIKTVMSRPRPTEMTVACAN
HHHHHHHHCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]