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The map label for this gene is avtA [H]

Identifier: 91213087

GI number: 91213087

Start: 4005364

End: 4006722

Strand: Direct

Name: avtA [H]

Synonym: UTI89_C4114

Alternate gene names: 91213087

Gene position: 4005364-4006722 (Clockwise)

Preceding gene: 91213086

Following gene: 91213090

Centisome position: 79.07

GC content: 51.95

Gene sequence:

>1359_bases
TTGCAGGATAAAGCACCGCTCACTCTTCAACAGACCGATTTGCACCCCAGCAAATGTAGCGTTATTGTTACCTTCCTTGC
TACAGAGTTCGACAGATATCCCGCTATGACATTCTCCCTTTTTGGTGACAAATTTACCCGCCACTCCGGCATTACGCTGC
TGATGGAAGATCTGAACGACGGTTTACGCACGCCTGGCGCGATTATGCTCGGCGGCGGTAATCCGGCGCAGATCCCTGAA
ATGCAGGACTACTTCCAGACGCTACTGACCGACATGCTGGAAAGTGGCAAAGCGACTGATGCACTGTGCAATTATGACGG
TCCACAGGGGAAAACGGAGCTACTCACACTGCTTGCCGGAATGCTGCGCGAGAAGTTGGGTTGGGATATCGAACCACAGA
ATATTGCACTAACAAACGGCAGCCAGAGCGCGTTTTTCTACTTATTTAATCTGTTTGCCGGACGCCGTGCCGATGGTCGG
GTCAAAAAAGTGCTGTTCCCGCTGGCACCGGAATACATTGGCTACGCTGACGCCGGACTGGAAGAAGATCTGTTTGTCTC
TGCGCGTCCGAATATTGAACTGCTGCCGGAAGGCCAGTTTAAATACCACGTCGATTTTGAGCATCTACATATTGGCGAAG
AAACCGGGATGATTTGCGTCTCCCGGCCGACGAATCCAACAGGCAATGTGATTACTGACGAAGAGTTGCTGAAGCTTGAC
GCGCTGGCGAATCAACACGGTATTCCGCTGGTGATTGATAACGCTTATGGCGTCCCGTTCCCGGGTATCATCTTCAGCGA
AGCGCGCCCGCTATGGAATCCGAATATCGTGCTGTGCATGAGTCTTTCCAAGCTGGGGCTACCTGGCTCCCGCTGCGGCA
TTATCATCGCCAATGAAAAAATCATCACCGCCATCACCAATATGAACGGCATTATCAGCCTGGCACCTGGCGGTATTGGT
CCGGCGATGATGTGTGAAATGATTAAGCGTAACGATCTGCTGCGCCTGTCTGAAACAGTCATCAAACCGTTTTACTACCA
GCGTGTTCAGGAAACTATCGCTATCATTCGCCGCTATTTACCGGAAGATCGCTGCCTGATTCATAAACCGGAAGGAGCCA
TTTTCCTCTGGCTATGGTTTAAGGATTTGCCCATTACGACCGAGCAGCTCTACCAGCGCCTGAAAGCACGCGGCGTGCTG
ATGGTGCCGGGGCACAACTTCTTCCCGGGACTGGATAAACCGTGGCCGCATACGCATCAATGTATGCGCATGAACTACGT
ACCAGAGCCGGAGAAAATTGAGGCGGGTGTGAAGATTCTGGCGGAAGAGATAGAAAGAGCCTGGGCTGAAAGCCACTAA

Upstream 100 bases:

>100_bases
GCTGGTCATCTGGGCTGGGCAACAGTGATTTTTCCGGCTTCCCGTTCGTCAGTACCTCGGGAAGCTGCCAACCAGGATAA
AATGTCAGCCCTAATCAGCA

Downstream 100 bases:

>100_bases
AAATTGCCTGATGCGCTACGCTTATCAGGCCTACATGATTTCTGCAATATATTGAATTTGGTAGAATTTGTAGGCCGGAT
AAGGCGTTTTAGCCGCATCC

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MQDKAPLTLQQTDLHPSKCSVIVTFLATEFDRYPAMTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPE
MQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGR
VKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLD
ALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIG
PAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVL
MVPGHNFFPGLDKPWPHTHQCMRMNYVPEPEKIEAGVKILAEEIERAWAESH

Sequences:

>Translated_452_residues
MQDKAPLTLQQTDLHPSKCSVIVTFLATEFDRYPAMTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPE
MQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGR
VKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLD
ALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIG
PAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVL
MVPGHNFFPGLDKPWPHTHQCMRMNYVPEPEKIEAGVKILAEEIERAWAESH
>Mature_452_residues
MQDKAPLTLQQTDLHPSKCSVIVTFLATEFDRYPAMTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPE
MQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGR
VKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLD
ALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIG
PAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVL
MVPGHNFFPGLDKPWPHTHQCMRMNYVPEPEKIEAGVKILAEEIERAWAESH

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=417, Percent_Identity=99.5203836930456, Blast_Score=859, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 50661; Mature: 50661

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKAPLTLQQTDLHPSKCSVIVTFLATEFDRYPAMTFSLFGDKFTRHSGITLLMEDLND
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEHHCCHHHCCCCCEEEEEHHHH
GLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAG
HHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHH
MLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGL
HHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCCCC
EEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLD
CCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCCCEEEEECCCCCCCCEECHHHHHHHH
ALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEK
HHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEECCE
IITAITNMNGIISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYL
EEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQ
CCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHH
CMRMNYVPEPEKIEAGVKILAEEIERAWAESH
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDKAPLTLQQTDLHPSKCSVIVTFLATEFDRYPAMTFSLFGDKFTRHSGITLLMEDLND
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEHHCCHHHCCCCCEEEEEHHHH
GLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAG
HHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHH
MLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGL
HHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCCCC
EEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLD
CCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCCCEEEEECCCCCCCCEECHHHHHHHH
ALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEK
HHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEECCE
IITAITNMNGIISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYL
EEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQ
CCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHH
CMRMNYVPEPEKIEAGVKILAEEIERAWAESH
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]