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The map label for this gene is ndh [H]

Identifier: 91210264

GI number: 91210264

Start: 1211020

End: 1212351

Strand: Direct

Name: ndh [H]

Synonym: UTI89_C1237

Alternate gene names: 91210264

Gene position: 1211020-1212351 (Clockwise)

Preceding gene: 91210263

Following gene: 91210265

Centisome position: 23.91

GC content: 52.33

Gene sequence:

>1332_bases
TTGGTTAATAAATTTAAGGGGGTCACGTTGACTACGCCATTGAAAAAAATTGTGATTGTCGGCGGCGGTGCTGGTGGGCT
GGAAATGGCAACACAGCTGGGGCATAAGCTGGGACGCAAGAAAAAAGCCAAAATTACGCTGGTCGATCGTAACCACAGCC
ACCTGTGGAAACCGCTGCTGCACGAAGTGGCGACTGGCTCGCTTGATGAAGGCGTCGATGCGTTGAGCTATCTGGCCCAT
GCGCGCAATCATGGTTTCCAGTTCCAGCTGGGTTCCGTAATTGATATTGATCGTGAAGCGAAAACAATCACTATTGCAGA
ACTGCGCGACGAGAAAGGTGAACTGCTGGTTCCGGAACGTAAAATCGCCTATGACACCCTGGTAATGGCGCTGGGTAGCA
CCTCTAACGATTTCAATACACCAGGTGTCAAAGAGAACTGCATTTTCCTCGATAACCCGCACCAGGCGCGTCGCTTCCAC
CAGGAGATGCTGAATCTGTTCCTGAAATACTCCGCCAACCTGGGCGCGAATGGCAAAGTAAACATTGCGATTGTCGGCGG
CGGCGCGACGGGTGTAGAACTCTCCGCTGAATTGCACAACGCGGTCAAGCAACTGCACAGTTACGGTTATAAAGGTCTGA
CCAACGAAGCCCTGAACGTAACGCTGGTAGAAGCGGGCGAACGTATTTTGCCTGCATTGCCGCCACGTATCTCTGCTGCG
GCCCATAGTGAGTTAACGAAACTAGGCGTTCGCGTGCTGACGCAAACCATGGTCACCAGTGCTGATGAAGGCGGCCTGCA
CACTAAAGATGGCGAATATATTGAGGCTGATCTGATGGTGTGGGCAGCCGGGATCAAAGCGCCAGACTTCCTGAAAGATA
TCGGTGGTCTTGAAACCAACCGTATCAACCAGCTGGTGGTGGAACCGACGCTGCAAACCACTCGCGATCCAGACATATAC
GCTATTGGCGACTGCGCGTCATGCCCGCGTCCGGAAGGGGGCTTTGTTCCGCCGCGCGCTCAGGCCGCACATCAGATGGC
AACCTGCGCAATGAACAACATTCTGGCGCAGATGAACGGTAAGCCGCTGAAAAATTATCAGTATAAAGATCACGGTTCGC
TGGTATCGCTGTCGAACTTTTCCACCGTCGGTAGCCTGATGGGTAACCTGACACGCGGCTCAATGATGATTGAAGGACGA
ATTGCGCGCTTTGTATACATCTCGCTGTACCGAATGCACCAGATTGCGCTGCATGGTTACTTTAAAACCGGATTAATGAT
GCTGGTGGGGAGTATTAACCGCGTTATCCGTCCACGTTTGAAGTTGCATTAA

Upstream 100 bases:

>100_bases
GACCAATGCACCATTCATGTTATTCTCAATAGCGAAGAACATTTTCATTGCTGTAACCTGTTGTTAATTAAGAGCTATGT
TAATAACCATTAATTAACAA

Downstream 100 bases:

>100_bases
TCGGCTTGTACTGGCGGATGCGGCGTAAACGCCTTATCCGCCCTGGACAAATGGTACGAGCGGTAGGCCTGATAAGACGC
GTTAAGCGTCGCATCAGGCA

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MVNKFKGVTLTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAH
ARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFH
QEMLNLFLKYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAA
AHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIY
AIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGR
IARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH

Sequences:

>Translated_443_residues
MVNKFKGVTLTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAH
ARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFH
QEMLNLFLKYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAA
AHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIY
AIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGR
IARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH
>Mature_443_residues
MVNKFKGVTLTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAH
ARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFH
QEMLNLFLKYSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAA
AHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIY
AIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGR
IARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=99.5391705069124, Blast_Score=893, Evalue=0.0,
Organism=Escherichia coli, GI1789065, Length=358, Percent_Identity=26.536312849162, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=464, Percent_Identity=26.2931034482759, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=349, Percent_Identity=26.3610315186246, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323794, Length=349, Percent_Identity=28.3667621776504, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48320; Mature: 48320

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKFKGVTLTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLL
CCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
HEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPER
HHHHCCCHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCCEEEEEEECCCCCCEECCCH
KIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKV
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
NIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAA
EEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHH
AHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCC
RINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNG
CCCEEEECCCHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGY
CCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FKTGLMMLVGSINRVIRPRLKLH
HHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MVNKFKGVTLTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLL
CCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
HEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDEKGELLVPER
HHHHCCCHHHHHHHHHHHHHHHCCCCEEECCCEEECCCCCCEEEEEEECCCCCCEECCCH
KIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKV
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
NIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAA
EEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHH
AHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHCCCCCC
RINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAAHQMATCAMNNILAQMNG
CCCEEEECCCHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGY
CCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FKTGLMMLVGSINRVIRPRLKLH
HHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]