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The map label for this gene is repA1 [H]

Identifier: 91206249

GI number: 91206249

Start: 1391

End: 2248

Strand: Direct

Name: repA1 [H]

Synonym: UTI89_P004

Alternate gene names: 91206249

Gene position: 1391-2248 (Clockwise)

Preceding gene: 91206248

Following gene: 91206251

Centisome position: 1.22

GC content: 56.76

Gene sequence:

>858_bases
GTGACTGATCTTCAACAAACGTATTACCGCCAGGTAAAGAACCCGAATCCGGTGTTTACACCCCGTAAAGGTGCCGGAAC
GTTGAAGTTCTGCGAAAAACTGATGGAAAAGGCGGTGGGCTTCACCTCCCGTTTTGATTTCGCCATTCATGTGGCGCATG
CCCGTTCCCGTGGTTTGCGTCGGCGCATGCCACCGGTGCTGCGTCGACGGGCTATTGATGCGCTGCTGCAGGGACTCTGT
TTTCACTATGATCCGCTGGCCAACCGCGTCCAGTGCTCCATCACCACGCTGGCCATTGAGTGCGGACTGGCGACAGAGTC
CGGTGCAGGAAAACTCTCCATCACCCGTGCCACCCGGGCCCTGACGTTCCTGTCAGAGCTGGGACTGATTACCTACCAGA
CGGAATATGACCCGCTTATCGGGTGCTACATTCCGACCGACATCACGTTCACACCGGCTCTGTTTGCTGCCCTTGATGTG
TCTGAGGATGCAGTGGCAGCTGCGCGCCGCAGTCGTGTTGAATGGGAAAACAAACAGCGCAAAAAGCAGGGGCTGGATAC
CCTGGGTATGGATGAGCTGATAGCGAAAGCCTGGCGTTTTGTGCGTGAGCGTTTCTGCAGTTACCAGACAGAGCTTAAGT
CCCGTGGAATAAAACGTGCCCGTGCGCGTCGTGATGCGAACAGGGAACGTCAGGATATCGTCACCCTGGTGAAACGGCAG
CTGACGCGTGAAATCTCGGAAGGGCGCTTCTCTGCCAGTCGTGAGGCGGTAAAACGTGAAGTGGAGCGTCGTGTGAAGGA
GCGCATGATTCTGTCACGTAACCGCAATTACAGCCGGCTGGCCACCGCTTCCCCCTGA

Upstream 100 bases:

>100_bases
CCAACAATTCAGCTATGCGGGGAGTATAGTCATATGCCCGGAAAAGTTCAAGACTTCTTTCTGTGCTCGCTCCTTCTGCG
CATTGTAAGTGCAGGATGGT

Downstream 100 bases:

>100_bases
AAGTGACCTCCTCAGAATAATCCGGCCTGCGCCGGAGGAATCCGCACGTCTGAAGCCCGCCAGTACAGAAAAAAACAGCA
CCACATACAAAAAACAACCT

Product: replication protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLC
FHYDPLANRVQCSITTLAIECGLATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDV
SEDAVAAARRSRVEWENKQRKKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIKRARARRDANRERQDIVTLVKRQ
LTREISEGRFSASREAVKREVERRVKERMILSRNRNYSRLATASP

Sequences:

>Translated_285_residues
MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLC
FHYDPLANRVQCSITTLAIECGLATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDV
SEDAVAAARRSRVEWENKQRKKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIKRARARRDANRERQDIVTLVKRQ
LTREISEGRFSASREAVKREVERRVKERMILSRNRNYSRLATASP
>Mature_284_residues
TDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCF
HYDPLANRVQCSITTLAIECGLATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDVS
EDAVAAARRSRVEWENKQRKKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIKRARARRDANRERQDIVTLVKRQL
TREISEGRFSASREAVKREVERRVKERMILSRNRNYSRLATASP

Specific function: This protein is essential for plasmid replication; it is involved in copy control functions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IncFII repA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017837
- InterPro:   IPR003446 [H]

Pfam domain/function: PF02387 IncFII_repA [H]

EC number: NA

Molecular weight: Translated: 32679; Mature: 32548

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLR
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEHHHHHHHHHH
RRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLATESGAGKLSITRATRA
HCCCHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHEEEEEECCCCCCCCCCEEHHHHHHH
LTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDVSEDAVAAARRSRVEWENKQR
HHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIKRARARRDANRERQDIVTLVKRQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LTREISEGRFSASREAVKREVERRVKERMILSRNRNYSRLATASP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLR
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEHHHHHHHHHH
RRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLATESGAGKLSITRATRA
HCCCHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHEEEEEECCCCCCCCCCEEHHHHHHH
LTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDVSEDAVAAARRSRVEWENKQR
HHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKQGLDTLGMDELIAKAWRFVRERFCSYQTELKSRGIKRARARRDANRERQDIVTLVKRQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LTREISEGRFSASREAVKREVERRVKERMILSRNRNYSRLATASP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7003300; 6163994; 3041379; 3050127; 2580099; 3019092; 2445727; 8396115 [H]