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The map label for this gene is nqrA [H]

Identifier: 89898811

GI number: 89898811

Start: 1163733

End: 1165148

Strand: Direct

Name: nqrA [H]

Synonym: CF1004

Alternate gene names: 89898811

Gene position: 1163733-1165148 (Clockwise)

Preceding gene: 89898810

Following gene: NA

Centisome position: 99.79

GC content: 39.34

Gene sequence:

>1416_bases
ATGAAAATAGCGATTACTCGGGGTTTAGATTTATCTTTGCAAGGGTCTCCTAAGGAGTCTGGGTTTTTAAAAAGGGTAGA
CCCGTCTCTAGTTTCCGTGGACCTGCGCCCTTATTCTGCCTTAGCTTTAAAGTTAAAGGTGGAGCAGGGAGACGTTATTT
CCTCAGGTTCTCCCGTTGCGGAATACAAAAACTTCCCTGGAGTTTTCATCACATCTCCTGTTTCCGGAATTGTAAAGGAA
ATACGTAGAGGAGAAAAACGATCCCTCCTAGATGTTGTTATCAAAAAAACTCCAGGACAAAACCTAACAGAGTATTCTTA
CGACTTAGCTAAGTTATCTCAACAAGAATTGTTGGATATCTTTAAGAAAGAAGGGCTTTTTGCCCTTTTTAAACAACGTC
CTTTTGACATCCCTGCTCTTCCAACGCAGACTCCTAGAGATGTCTTTATTAACTTAGCGGATAACCGTCCTTTCACCCCA
TCTACAGAAAAACATCTCGCCGTCTTTTCTTCCAGAGAAGAAGGTCTTTATGTTTTTAACGTTGGGGTTCGCGCTATAGC
GAAACTCTTTGGCTTATGTCCCCATGTTGTTTCTACTGATAGAGTAGCTATTCCTGAAAAAGACTTAAAATCTATAGCTC
ATATACACAAAATCACTGGGCCCTATCCTTCAGGATCACCCTCGACACACATTCACTACATAGCTCCTATTACTTGTGAA
AAAGATATAGTTTTTACTATCTCTTTCCATGAGGTTTTAACCATAGGCCATCTCTTCTTAAAAGGAAGAATTCTAAATGA
ACAAGTCGTTGCTCTAGCGGGATCAGGATTAAAACCTTCCCTAAGACGTTATGTTATCACCACTAAAGGAGCAGATTTCC
AAAGTTTGCTTCCTTTGGAAGATATCTCTTCGGAAAACGTATCTTTGATTTCTGGAGATCCTTTAACTGGAAGACTTTGC
GACAAAGAAAGCCTTCCTTGTCTGGGTATGAGAGATACAACAATCTCTGTCATTCCCAACCCAAAAACACGACAAGCCTT
CAACTTTCTAAGATTAGGAATTAATAAACCCACCCGCACAAGAACCTATCTTTCTGGATTCTTAAAAAGAAAACATACCT
ATATGGATCCAGATACAAATCTCCACGGGGAAATACGACCCATCATAGATACAGAAATTTATGATAAGGTCATGCCAATG
AAGATCCCTGTTGTTCCTCTAATTAAAGCTGTGATTACTAAGGATTTTGAGTTGGCTTGCAAGCTTGGATTTTTGGAAGT
TTGTCCCGAAGATTTTGCTCTCCCCACCTTCATAGATCCATCGAAAACAGAAATGTTAACAATTATCAAAGAATCTCTAA
AACAATACGCTAAAGAAACTGGTATCTTGAATCCAGAACATGAAGAAACAGAGTAA

Upstream 100 bases:

>100_bases
CCCGCTCCCGTTTCTAGTAAAAAAACAAAAACAACTTCCACGAAAAAAAATAAGAAAAAAAACTGGATTCCCTTATAAAA
ACGCCTATAATCCCTGAAGT

Downstream 100 bases:

>100_bases
AGTTCTTCGAAGAACCTATATTCTTGCCGAAGCTATCATCTCTAAAATTAACGGAGTTGCATAAGAAATAATCATATCAG
CTCCTGCTCGTTTTATAGAG

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKIAITRGLDLSLQGSPKESGFLKRVDPSLVSVDLRPYSALALKLKVEQGDVISSGSPVAEYKNFPGVFITSPVSGIVKE
IRRGEKRSLLDVVIKKTPGQNLTEYSYDLAKLSQQELLDIFKKEGLFALFKQRPFDIPALPTQTPRDVFINLADNRPFTP
STEKHLAVFSSREEGLYVFNVGVRAIAKLFGLCPHVVSTDRVAIPEKDLKSIAHIHKITGPYPSGSPSTHIHYIAPITCE
KDIVFTISFHEVLTIGHLFLKGRILNEQVVALAGSGLKPSLRRYVITTKGADFQSLLPLEDISSENVSLISGDPLTGRLC
DKESLPCLGMRDTTISVIPNPKTRQAFNFLRLGINKPTRTRTYLSGFLKRKHTYMDPDTNLHGEIRPIIDTEIYDKVMPM
KIPVVPLIKAVITKDFELACKLGFLEVCPEDFALPTFIDPSKTEMLTIIKESLKQYAKETGILNPEHEETE

Sequences:

>Translated_471_residues
MKIAITRGLDLSLQGSPKESGFLKRVDPSLVSVDLRPYSALALKLKVEQGDVISSGSPVAEYKNFPGVFITSPVSGIVKE
IRRGEKRSLLDVVIKKTPGQNLTEYSYDLAKLSQQELLDIFKKEGLFALFKQRPFDIPALPTQTPRDVFINLADNRPFTP
STEKHLAVFSSREEGLYVFNVGVRAIAKLFGLCPHVVSTDRVAIPEKDLKSIAHIHKITGPYPSGSPSTHIHYIAPITCE
KDIVFTISFHEVLTIGHLFLKGRILNEQVVALAGSGLKPSLRRYVITTKGADFQSLLPLEDISSENVSLISGDPLTGRLC
DKESLPCLGMRDTTISVIPNPKTRQAFNFLRLGINKPTRTRTYLSGFLKRKHTYMDPDTNLHGEIRPIIDTEIYDKVMPM
KIPVVPLIKAVITKDFELACKLGFLEVCPEDFALPTFIDPSKTEMLTIIKESLKQYAKETGILNPEHEETE
>Mature_471_residues
MKIAITRGLDLSLQGSPKESGFLKRVDPSLVSVDLRPYSALALKLKVEQGDVISSGSPVAEYKNFPGVFITSPVSGIVKE
IRRGEKRSLLDVVIKKTPGQNLTEYSYDLAKLSQQELLDIFKKEGLFALFKQRPFDIPALPTQTPRDVFINLADNRPFTP
STEKHLAVFSSREEGLYVFNVGVRAIAKLFGLCPHVVSTDRVAIPEKDLKSIAHIHKITGPYPSGSPSTHIHYIAPITCE
KDIVFTISFHEVLTIGHLFLKGRILNEQVVALAGSGLKPSLRRYVITTKGADFQSLLPLEDISSENVSLISGDPLTGRLC
DKESLPCLGMRDTTISVIPNPKTRQAFNFLRLGINKPTRTRTYLSGFLKRKHTYMDPDTNLHGEIRPIIDTEIYDKVMPM
KIPVVPLIKAVITKDFELACKLGFLEVCPEDFALPTFIDPSKTEMLTIIKESLKQYAKETGILNPEHEETE

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 52468; Mature: 52468

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAITRGLDLSLQGSPKESGFLKRVDPSLVSVDLRPYSALALKLKVEQGDVISSGSPVA
CEEEEECCCEEEECCCCCCCCCCEECCCCEEEEECCCCEEEEEEEEECCCCEECCCCCHH
EYKNFPGVFITSPVSGIVKEIRRGEKRSLLDVVIKKTPGQNLTEYSYDLAKLSQQELLDI
HHCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
FKKEGLFALFKQRPFDIPALPTQTPRDVFINLADNRPFTPSTEKHLAVFSSREEGLYVFN
HHHCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEEEECCCCCEEEEE
VGVRAIAKLFGLCPHVVSTDRVAIPEKDLKSIAHIHKITGPYPSGSPSTHIHYIAPITCE
CCHHHHHHHHCCCCHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEC
KDIVFTISFHEVLTIGHLFLKGRILNEQVVALAGSGLKPSLRRYVITTKGADFQSLLPLE
CCEEEEEEHHHHHHHHHHHHHCEECCCCEEEEECCCCCCCCEEEEEEECCCCHHHCCCHH
DISSENVSLISGDPLTGRLCDKESLPCLGMRDTTISVIPNPKTRQAFNFLRLGINKPTRT
HCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHH
RTYLSGFLKRKHTYMDPDTNLHGEIRPIIDTEIYDKVMPMKIPVVPLIKAVITKDFELAC
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHCCCHHHHH
KLGFLEVCPEDFALPTFIDPSKTEMLTIIKESLKQYAKETGILNPEHEETE
CCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKIAITRGLDLSLQGSPKESGFLKRVDPSLVSVDLRPYSALALKLKVEQGDVISSGSPVA
CEEEEECCCEEEECCCCCCCCCCEECCCCEEEEECCCCEEEEEEEEECCCCEECCCCCHH
EYKNFPGVFITSPVSGIVKEIRRGEKRSLLDVVIKKTPGQNLTEYSYDLAKLSQQELLDI
HHCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
FKKEGLFALFKQRPFDIPALPTQTPRDVFINLADNRPFTPSTEKHLAVFSSREEGLYVFN
HHHCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHEEEEECCCCCEEEEE
VGVRAIAKLFGLCPHVVSTDRVAIPEKDLKSIAHIHKITGPYPSGSPSTHIHYIAPITCE
CCHHHHHHHHCCCCHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEC
KDIVFTISFHEVLTIGHLFLKGRILNEQVVALAGSGLKPSLRRYVITTKGADFQSLLPLE
CCEEEEEEHHHHHHHHHHHHHCEECCCCEEEEECCCCCCCCEEEEEEECCCCHHHCCCHH
DISSENVSLISGDPLTGRLCDKESLPCLGMRDTTISVIPNPKTRQAFNFLRLGINKPTRT
HCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHH
RTYLSGFLKRKHTYMDPDTNLHGEIRPIIDTEIYDKVMPMKIPVVPLIKAVITKDFELAC
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHCCCHHHHH
KLGFLEVCPEDFALPTFIDPSKTEMLTIIKESLKQYAKETGILNPEHEETE
CCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]