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The map label for this gene is argS

Identifier: 89898642

GI number: 89898642

Start: 984373

End: 986061

Strand: Direct

Name: argS

Synonym: CF0835

Alternate gene names: 89898642

Gene position: 984373-986061 (Clockwise)

Preceding gene: 89898641

Following gene: 89898644

Centisome position: 84.41

GC content: 38.07

Gene sequence:

>1689_bases
ATGACTCTTCTTTCTTATTTATCTTCTCTATGTCGAGAAGCAACTCTATCAGCGTTTCCTCAAGTAGAAAATCCTTCTCC
CGACATTACACAATCCACTAAAGAACATTTCGGTCATTATCAATGTAATGATGCGATGAAACTTGATCGCACATTAAAAA
TGGCTCCTAGAGCTATTGCTGAGGCGATTGTTAACAACCTTCCTAAAGACAACTTTTCTTCTGTAGAAGTTGCTGGTGCA
GGTTTTATTAACTTCACATTTTCCAAAGAATTTTTAAAACAGCGTTTGGAGACATTTTCTGCAGATTTATCTTCAGGATT
TTGCGTTAAGGATCCTAAAAAAATCGTCATAGATTTTTCTTCTCCAAATATTGCTAAAGATATGCATGTGGGTCATCTAC
GCTCTACAATCATAGGAGATTGCCTTGCTCGTGTATTTTCTTTTGTTGGCAATGATGTTTTAAGATTGAATCACATTGGT
GATTGGGGAACAGCTTTTGGCATGTTAATCACCTATCTTCAAGAAGAAGCCTCTGAAGATGTGGGAAATCTTGAAGATTT
GACAGCTTTGTATAAAAAAGCACACGCACGTTTTGCTGAGGATGTGGAATTTAAAAAGCGCTCGCAAGCTAATGTTGTTG
CTTTACAATCTGGGGATCCCTCAGCATTAAATTTATGGAAACACATTTGTGAAATTTCTGAGCGCGCTTTTCAAAAGATT
TATGATATTTTAGGTGTTGCTATAGAAAAACGTGGTGAGTCTTTCTATAATCCTTTTCTTCCTGAGATTATCCAAGATTT
AGAAAATAAAAAACTCATCACGGTTTCTGATAATGCTAAATGTGTTTTCCACGAAGGATTTTCTATTCCCCTAATGGTTC
AGAAAAGTGATGGCGGCTATAACTATGCGACTACAGATTTAGCTGCTATGCGTTATCGCGTAGAAAAAGACCATGCGGAT
AAAATCATCATTGTCACTGATATGGGACAATCCTTACATTTCCAACTTCTAGAAGCTACGGCATTAGCTGCTGGGTACCT
TCGCGATAAAGAAACCTTTTCTCATGTAGGTTTTGGTCTTGTCCTTGATTCTGAAGGGAAAAAATTTAAAACACGTTCTG
GAGAGAATATCAAGCTCAAGGAATTATTAAATACAGCTGTAGATCAAGCCGTAGCCACCCTAAAAGAACACCGCCCGGAA
ATGTCCGAGGAAGAAATCTCTCAACGTGCGCCTATTCTTGGTATCAATGCTATCAAATATGCAGATCTTTCCTCACACCG
TGTGAGTGATTATGTCTTCTCCTTTGAGAAGATGCTCCGTTTTGAAGGAAATACTGCGATGTTTCTTCTTTATGCTTACG
TACGTATTCAAGGGATAAAACGACGATTAAACATTGAAAAATTAAACTTAGAAGCCGTGGTAAACATCCAAGAGCCTGCT
GAAGAGGCTTTAGCTTTAGCCCTATTGCGCTTTCCAGAAGCTATTGATGTAACTCTTAAAGAACTTTGTCCGCATTTCCT
AACAGATTATCTTTATATGCTCACGAACAAGTTCAATGCCTTTTTCAGGGATTGTCACATCGAGGGATCTCCTTATCAAC
AAGAGCGCCTATATCTTTGTGCTCTTGTTGAAAAGACCTTAGCTACAGGAATGCATTTACTAGGATTACAAACTCTAGAC
AGGTTGTAA

Upstream 100 bases:

>100_bases
AGGAGACCTATCAGATAGCGACCGACAGAATTATGAGCAAAATAGCGGAGCTAAAAACTTGGTATGAAAACGGCTGTATT
GGAGAGGTACCTTAAATAGT

Downstream 100 bases:

>100_bases
GATTAGGGAGCTACAGGATCTAAATGTAATAAATGGATCCTTGCTCCTAAAGAGTTTAACTTCTCTACCCAATTATAATA
TCCTCGATCTAACAATTGGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MTLLSYLSSLCREATLSAFPQVENPSPDITQSTKEHFGHYQCNDAMKLDRTLKMAPRAIAEAIVNNLPKDNFSSVEVAGA
GFINFTFSKEFLKQRLETFSADLSSGFCVKDPKKIVIDFSSPNIAKDMHVGHLRSTIIGDCLARVFSFVGNDVLRLNHIG
DWGTAFGMLITYLQEEASEDVGNLEDLTALYKKAHARFAEDVEFKKRSQANVVALQSGDPSALNLWKHICEISERAFQKI
YDILGVAIEKRGESFYNPFLPEIIQDLENKKLITVSDNAKCVFHEGFSIPLMVQKSDGGYNYATTDLAAMRYRVEKDHAD
KIIIVTDMGQSLHFQLLEATALAAGYLRDKETFSHVGFGLVLDSEGKKFKTRSGENIKLKELLNTAVDQAVATLKEHRPE
MSEEEISQRAPILGINAIKYADLSSHRVSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLNIEKLNLEAVVNIQEPA
EEALALALLRFPEAIDVTLKELCPHFLTDYLYMLTNKFNAFFRDCHIEGSPYQQERLYLCALVEKTLATGMHLLGLQTLD
RL

Sequences:

>Translated_562_residues
MTLLSYLSSLCREATLSAFPQVENPSPDITQSTKEHFGHYQCNDAMKLDRTLKMAPRAIAEAIVNNLPKDNFSSVEVAGA
GFINFTFSKEFLKQRLETFSADLSSGFCVKDPKKIVIDFSSPNIAKDMHVGHLRSTIIGDCLARVFSFVGNDVLRLNHIG
DWGTAFGMLITYLQEEASEDVGNLEDLTALYKKAHARFAEDVEFKKRSQANVVALQSGDPSALNLWKHICEISERAFQKI
YDILGVAIEKRGESFYNPFLPEIIQDLENKKLITVSDNAKCVFHEGFSIPLMVQKSDGGYNYATTDLAAMRYRVEKDHAD
KIIIVTDMGQSLHFQLLEATALAAGYLRDKETFSHVGFGLVLDSEGKKFKTRSGENIKLKELLNTAVDQAVATLKEHRPE
MSEEEISQRAPILGINAIKYADLSSHRVSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLNIEKLNLEAVVNIQEPA
EEALALALLRFPEAIDVTLKELCPHFLTDYLYMLTNKFNAFFRDCHIEGSPYQQERLYLCALVEKTLATGMHLLGLQTLD
RL
>Mature_561_residues
TLLSYLSSLCREATLSAFPQVENPSPDITQSTKEHFGHYQCNDAMKLDRTLKMAPRAIAEAIVNNLPKDNFSSVEVAGAG
FINFTFSKEFLKQRLETFSADLSSGFCVKDPKKIVIDFSSPNIAKDMHVGHLRSTIIGDCLARVFSFVGNDVLRLNHIGD
WGTAFGMLITYLQEEASEDVGNLEDLTALYKKAHARFAEDVEFKKRSQANVVALQSGDPSALNLWKHICEISERAFQKIY
DILGVAIEKRGESFYNPFLPEIIQDLENKKLITVSDNAKCVFHEGFSIPLMVQKSDGGYNYATTDLAAMRYRVEKDHADK
IIIVTDMGQSLHFQLLEATALAAGYLRDKETFSHVGFGLVLDSEGKKFKTRSGENIKLKELLNTAVDQAVATLKEHRPEM
SEEEISQRAPILGINAIKYADLSSHRVSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLNIEKLNLEAVVNIQEPAE
EALALALLRFPEAIDVTLKELCPHFLTDYLYMLTNKFNAFFRDCHIEGSPYQQERLYLCALVEKTLATGMHLLGLQTLDR
L

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=590, Percent_Identity=41.5254237288136, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI197100773, Length=526, Percent_Identity=32.5095057034221, Blast_Score=222, Evalue=8e-58,
Organism=Escherichia coli, GI1788184, Length=578, Percent_Identity=39.9653979238754, Blast_Score=431, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI71985061, Length=592, Percent_Identity=38.6824324324324, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71985068, Length=551, Percent_Identity=39.3829401088929, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17532153, Length=483, Percent_Identity=24.223602484472, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320548, Length=540, Percent_Identity=29.0740740740741, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6321883, Length=476, Percent_Identity=27.7310924369748, Blast_Score=180, Evalue=5e-46,
Organism=Drosophila melanogaster, GI18859963, Length=594, Percent_Identity=37.8787878787879, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=521, Percent_Identity=30.7101727447217, Blast_Score=165, Evalue=7e-41,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CHLFF (Q253D1)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515752.1
- ProteinModelPortal:   Q253D1
- SMR:   Q253D1
- STRING:   Q253D1
- GeneID:   3958916
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0835
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- BioCyc:   CFEL264202:CF0835-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63380; Mature: 63249

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSYLSSLCREATLSAFPQVENPSPDITQSTKEHFGHYQCNDAMKLDRTLKMAPRAIA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHH
EAIVNNLPKDNFSSVEVAGAGFINFTFSKEFLKQRLETFSADLSSGFCVKDPKKIVIDFS
HHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
SPNIAKDMHVGHLRSTIIGDCLARVFSFVGNDVLRLNHIGDWGTAFGMLITYLQEEASED
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
VGNLEDLTALYKKAHARFAEDVEFKKRSQANVVALQSGDPSALNLWKHICEISERAFQKI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
YDILGVAIEKRGESFYNPFLPEIIQDLENKKLITVSDNAKCVFHEGFSIPLMVQKSDGGY
HHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEEEECCCEEEEECCCCEEEEEEECCCCC
NYATTDLAAMRYRVEKDHADKIIIVTDMGQSLHFQLLEATALAAGYLRDKETFSHVGFGL
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCEEE
VLDSEGKKFKTRSGENIKLKELLNTAVDQAVATLKEHRPEMSEEEISQRAPILGINAIKY
EECCCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCEEE
ADLSSHRVSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLNIEKLNLEAVVNIQEPA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECHHHH
EEALALALLRFPEAIDVTLKELCPHFLTDYLYMLTNKFNAFFRDCHIEGSPYQQERLYLC
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALVEKTLATGMHLLGLQTLDRL
HHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TLLSYLSSLCREATLSAFPQVENPSPDITQSTKEHFGHYQCNDAMKLDRTLKMAPRAIA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHH
EAIVNNLPKDNFSSVEVAGAGFINFTFSKEFLKQRLETFSADLSSGFCVKDPKKIVIDFS
HHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
SPNIAKDMHVGHLRSTIIGDCLARVFSFVGNDVLRLNHIGDWGTAFGMLITYLQEEASED
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
VGNLEDLTALYKKAHARFAEDVEFKKRSQANVVALQSGDPSALNLWKHICEISERAFQKI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
YDILGVAIEKRGESFYNPFLPEIIQDLENKKLITVSDNAKCVFHEGFSIPLMVQKSDGGY
HHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEEEECCCEEEEECCCCEEEEEEECCCCC
NYATTDLAAMRYRVEKDHADKIIIVTDMGQSLHFQLLEATALAAGYLRDKETFSHVGFGL
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCEEE
VLDSEGKKFKTRSGENIKLKELLNTAVDQAVATLKEHRPEMSEEEISQRAPILGINAIKY
EECCCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCEEE
ADLSSHRVSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLNIEKLNLEAVVNIQEPA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECHHHH
EEALALALLRFPEAIDVTLKELCPHFLTDYLYMLTNKFNAFFRDCHIEGSPYQQERLYLC
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALVEKTLATGMHLLGLQTLDRL
HHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA