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The map label for this gene is clpB2 [H]

Identifier: 89898459

GI number: 89898459

Start: 754972

End: 757512

Strand: Direct

Name: clpB2 [H]

Synonym: CF0652

Alternate gene names: 89898459

Gene position: 754972-757512 (Clockwise)

Preceding gene: 89898452

Following gene: 89898462

Centisome position: 64.74

GC content: 41.24

Gene sequence:

>2541_bases
ATGTTTGAGAAGTTTACTAACAGAGCAAAACAAGTCATTAAATTGGCTAAAAAAGAGGCTCAGAGGTTAAATCATAACTA
TCTAGGCACAGAGCATATACTCTTAGGCTTACTCAAACTAGGTCAGGGCGTAGCCGTAAATGTACTGCGCAACTTAGGAG
TAGATTTTGACACTGCGAAACAAGAAGTCGAGCGTCTGATCGGTTATGGACCTGAAATCCAGGTCTATGGTGATCCTGCC
CTTACTGGAAGAGTAAAAAAATCTTTTGAATCTGCAAATGAAGAAGCTGGGGTTTTAGAACATAATTACGTAGGTACTGA
ACATCTTCTCTTAGGCATCTTAAATCAAGCCGATGGAGTTGCTTTACAGGTTTTAGAAAACTTACATATTGATCCCAGAG
AAGTTCGTAAGGAAATTCTTAAGGAATTAGAAACATTCAATCTTCAACTTCCCCCATCATCATCTTCTTCTAATCCTAGA
GGAAATTCATCTTCATCCTCTAAATCTTCTTCCCTAGGTCATACTCTGGGAGGAGAAAAAAATGATAAGTTATCGGCATT
AAAAGCTTACGGTTATGATTTAACCGAAATGTTTCGTGAGTCTAAGCTTGATCCTGTCATAGGTCGTTCTACGGAAGTAG
AGCGCCTGATCCTTATCCTATGTCGCAGAAGAAAAAATAACCCTGTACTTATCGGGGAAGCTGGTGTAGGTAAAACGGCT
ATCGTTGAAGGATTAGCGCAAAAGATCATTTCCAATGAAGTTCCCGATACTTTACGCAAAAAACGTTTAATTACCCTAGA
TCTTGCCTTAATGATTGCAGGAACTAAATATCGCGGTCAATTTGAAGAACGTATCAAAGCAGTTATGGATGAAGTCCGCA
AACACGGAAACATCCTTTTATTTATCGATGAGCTACATACAATCGTAGGTGCGGGTGCTGCTGAAGGAGCTATTGATGCT
TCTAACATCTTAAAACCAGCTCTAGCACGTGGAGAAATTCAGTGTATTGGAGCCACAACAATTGATGAATACCGCAAGCA
TATTGAAAAAGATGCTGCTTTAGAACGCAGATTCCAAAAAATTATTGTGCACCCACCTAGTGTAGATGAAACTATAGAAA
TTCTACGTGGGTTAAAAAAGAAATACGAAGAGCATCATAATGTTTCTATTACAGAAGAAGCATTGAAAGCTGCGGCCACT
TTATCTGATCAGTATGTTCACGGTCGTTTCCTTCCAGACAAAGCTATTGATTTGCTTGATGAGGCTGGAGCGCGTGTACG
TGTCAATACCATGGATCAGCCTACAGAGTTAATGAAACTCGAAGCTGAGATTGAAACTACGAAGCTCGCTAAAGAGCAAG
CGATTGGCACACAAGAATACGAAAAGGCGGCAGGATTACGCGACGAAGAGAAAAAGCTTCGAGAACGTCTCTCCAACATG
AAACAAGAATGGGAAAATCACAAAGAAGAGCATCAGATTCCCGTGGATGAGGAAGCAGTTGCTCAAGTGGTCTCCTTACA
AACAGGTATTCCTTCCGCAAGGCTTACTGAAGCTGAAAGTGAAAAGTTACTTAAGTTAGAAGATACTCTACGTAAAAAAG
TCATAGGTCAAGATCAGGCAGTAGCAAGCATTTGCCGAGCTATTCGTCGTTCAAGAACTGGCATTAAAGATCCCAACCGT
CCAACAGGCTCATTCTTATTCCTAGGCCCCACTGGAGTAGGGAAAACGTTGCTAGCTCAACAGATTGCCATCGAAATGTT
TGGTGGTGAGGATGCTTTAATTCAAGTAGATATGTCTGAGTACATGGAGAAGTTCGCCGCCACCAAAATGATGGGATCGC
CTCCAGGGTACGTTGGTCACGAGGAAGGTGGTCATCTTACGGAACAAGTACGTCGTCGTCCTTACTGTGTTGTTTTATTC
GATGAGATTGAAAAAGCTCATCCCGACATTATGGACTTAATGTTGCAAATTCTAGAGCAAGGACGTCTTACAGACTCGTT
TGGTCGCAAGATTAATTTCCGTCATGCGATCATTATCATGACTTCGAACTTAGGTGCGGACTTAATTAAAAAGAGTGGGG
AAATTGGTTTTGGCACTCGATCGAATTTTGATTACAAAGTCATCCAAGAAAAAATCGAAAATGCTGTGAAGAAGCATTTA
AAACCGGAGTTTATCAACCGTTTGGATGAAAGTGTCATCTTCCGTCCTTTAGAGAAAGATGCTTTATCTCAGATTATCCA
TTTAGAAATTAATAAACTGGATTCCCGTTTGAAAAATTACCAAATGGCTTTAAGCATTCCAGATTCCGTGATTTCTTTCT
TAGTTACGAAAGGCCACTCTCCAGAAATGGGAGCACGACCCTTACGTCGAGTTATTGAGCAGTATCTTGAAGATCCTCTT
GCGGAGCTTTTGCTTAAGGAGTCTTGCCGTCAAGAAGCGAGAAAGCTTCGTGCTAGTCTCACAGAAGATCGAGTAACTTT
CGAGCGCGAGGAAGAACAATCTGAAAGTATTCCGGCAACTATACCGACTGGGGAGTCATAG

Upstream 100 bases:

>100_bases
TTAATCTCTGTAATACCACATCTATTTATCGAAGAGTTGCATCATTATTTTAAATGTCGTATATGCTTAAGGAAAGTTCT
ACCCGGTCTTTTAGGTTTTT

Downstream 100 bases:

>100_bases
AAATCTCTATGACCCCACCGCCTAGGCACCGCTCTCCGTCATAGAAGGCAATAGCTTGCCCTGGGGTGATTGCCTTCACG
GGTGAAGCAAATCGCACGAG

Product: ATP-dependent Clp endopeptidase ATP-binding chain B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 846

Protein sequence:

>846_residues
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAKQEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGVALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPR
GNSSSSSKSSSLGHTLGGEKNDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDA
SNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQKIIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAAT
LSDQYVHGRFLPDKAIDLLDEAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQAVASICRAIRRSRTGIKDPNR
PTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLF
DEIEKAHPDIMDLMLQILEQGRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHSPEMGARPLRRVIEQYLEDPL
AELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPATIPTGES

Sequences:

>Translated_846_residues
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAKQEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGVALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPR
GNSSSSSKSSSLGHTLGGEKNDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDA
SNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQKIIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAAT
LSDQYVHGRFLPDKAIDLLDEAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQAVASICRAIRRSRTGIKDPNR
PTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLF
DEIEKAHPDIMDLMLQILEQGRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHSPEMGARPLRRVIEQYLEDPL
AELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPATIPTGES
>Mature_846_residues
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAKQEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGVALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPR
GNSSSSSKSSSLGHTLGGEKNDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDA
SNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQKIIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAAT
LSDQYVHGRFLPDKAIDLLDEAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQAVASICRAIRRSRTGIKDPNR
PTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLF
DEIEKAHPDIMDLMLQILEQGRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHSPEMGARPLRRVIEQYLEDPL
AELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPATIPTGES

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=35.9060402684564, Blast_Score=192, Evalue=2e-48,
Organism=Escherichia coli, GI1788943, Length=734, Percent_Identity=46.3215258855586, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=798, Percent_Identity=35.5889724310777, Blast_Score=474, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6320464, Length=689, Percent_Identity=42.8156748911466, Blast_Score=558, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6323002, Length=926, Percent_Identity=35.85313174946, Blast_Score=513, Evalue=1e-146,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94756; Mature: 94756

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
QEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGV
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
ALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPRGNSSSSSKSSSLGHTLGGEK
HHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCHHCCCHHCCCCC
NDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
CCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHH
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILL
HHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
FIDELHTIVGAGAAEGAIDASNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQK
EHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
IIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAATLSDQYVHGRFLPDKAIDLLD
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
HCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHH
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQA
HHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCHHH
VASICRAIRRSRTGIKDPNRPTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSE
HHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHH
YMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQ
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEHHHHHHHCCHHHHHHHHHHHC
GRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
CCCCHHHCCEEECCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHS
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCC
PEMGARPLRRVIEQYLEDPLAELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IPTGES
CCCCCC
>Mature Secondary Structure
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGVDFDTAK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
QEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEAGVLEHNYVGTEHLLLGILNQADGV
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
ALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSNPRGNSSSSSKSSSLGHTLGGEK
HHHHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCHHCCCHHCCCCC
NDKLSALKAYGYDLTEMFRESKLDPVIGRSTEVERLILILCRRRKNNPVLIGEAGVGKTA
CCHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHH
IVEGLAQKIISNEVPDTLRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILL
HHHHHHHHHHHCCCCHHHHHHHHHHEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEE
FIDELHTIVGAGAAEGAIDASNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQK
EHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
IIVHPPSVDETIEILRGLKKKYEEHHNVSITEEALKAAATLSDQYVHGRFLPDKAIDLLD
HCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EAGARVRVNTMDQPTELMKLEAEIETTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLSNM
HCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHH
KQEWENHKEEHQIPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRKKVIGQDQA
HHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCHHH
VASICRAIRRSRTGIKDPNRPTGSFLFLGPTGVGKTLLAQQIAIEMFGGEDALIQVDMSE
HHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHH
YMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQ
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEHHHHHHHCCHHHHHHHHHHHC
GRLTDSFGRKINFRHAIIIMTSNLGADLIKKSGEIGFGTRSNFDYKVIQEKIENAVKKHL
CCCCHHHCCEEECCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
KPEFINRLDESVIFRPLEKDALSQIIHLEINKLDSRLKNYQMALSIPDSVISFLVTKGHS
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCC
PEMGARPLRRVIEQYLEDPLAELLLKESCRQEARKLRASLTEDRVTFEREEEQSESIPAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IPTGES
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]