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The map label for this gene is rpiA

Identifier: 89898178

GI number: 89898178

Start: 435821

End: 436522

Strand: Direct

Name: rpiA

Synonym: CF0371

Alternate gene names: 89898178

Gene position: 435821-436522 (Clockwise)

Preceding gene: 89898177

Following gene: 89898179

Centisome position: 37.37

GC content: 38.18

Gene sequence:

>702_bases
GTGAAAGAAGATCCCTATTTAGATGTGAAAAAGCGTTTAGCTCGTGAAGCAGCAGCTTTAGTAACTTCTGGAATGCTTGT
GGGACTGGGAAGTGGTTCTACATCTAGAGAATTTATTAAAGCTATTGCTGAAAGGTTGGCGAAGGAAAACTTAGATATTT
GTGCGGTAGCTTCTTCGCAAGAGTCTTATTCTTTAGCGAGTAGTTTAGGAATTCCCCTGATTGATGATGAAAATTTTACT
TCTGTCGATCTTGTTGTTGATGGAGCCGATGAGATAGATCCCCAACTGCGTATGATTAAAGGTGGTGGAGGCGCTATTTT
TAGAGAGAAGATTCTGTTGCAATCGAGTCAACGACGTTTGATACTTGCTGATGAAAGTAAAAGTGTTAAGGTTTTAGGGA
AATTTGGTCTTCCCGTAGAGATTAGTCCTTATGGTAGATCTTCTATTATAGCTGCCTTAGAAGCTATAGGATATTTGGGA
AATTTAAGAAAGAATTCTCGAGGGGGATTTTTTATCACCAATAATGGAAATTATATTTACGATATTCATACACCGAATAT
ATATCCTCATCCCGAGGAAGATCTTTTGAAGCTGTTACAAATTCATGGTATTATTGAGGTCGGGTTTGTTATAGCGAATG
TTGAGGTATGGTTTGGTTATACCAATGGTCAGATTTGCAAAGAGAACACCGGCATAGTATGA

Upstream 100 bases:

>100_bases
TTGCCATTGTATTAATATGCCTCAGGCTTTTAGTTTTTATACGAAAATATAGAGATTGTGTGAGCCAAAGGATGGAGAGA
AGTAAAGAAATAGAGGTGTT

Downstream 100 bases:

>100_bases
GTATAGAGAAAGAGCTGCTCCAGGATACCCCTTTAGTTTTGCTTAACTTTTATAAGTTAGTAAGCTTTTGTCACTACGCA
GGGATTATCCTTGGTACCGA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQESYSLASSLGIPLIDDENFT
SVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRLILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLG
NLRKNSRGGFFITNNGNYIYDIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV

Sequences:

>Translated_233_residues
MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQESYSLASSLGIPLIDDENFT
SVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRLILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLG
NLRKNSRGGFFITNNGNYIYDIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV
>Mature_233_residues
MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQESYSLASSLGIPLIDDENFT
SVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRLILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLG
NLRKNSRGGFFITNNGNYIYDIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=223, Percent_Identity=33.1838565022422, Blast_Score=111, Evalue=5e-25,
Organism=Escherichia coli, GI1789280, Length=203, Percent_Identity=38.9162561576355, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17551758, Length=230, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=30.4545454545455, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=30.5164319248826, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_CHLFF (Q254Z5)

Other databases:

- EMBL:   AP006861
- RefSeq:   YP_515288.1
- ProteinModelPortal:   Q254Z5
- SMR:   Q254Z5
- STRING:   Q254Z5
- GeneID:   3958879
- GenomeReviews:   AP006861_GR
- KEGG:   cfe:CF0371
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   CFEL264202:CF0371-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25374; Mature: 25374

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQ
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
ESYSLASSLGIPLIDDENFTSVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRL
CHHHHHHHCCCEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEE
ILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLGNLRKNSRGGFFITNNGNYIY
EEECCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEE
DIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV
EEECCCCCCCCHHHHHHHHHHHCHHEEEEEEEEEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQ
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
ESYSLASSLGIPLIDDENFTSVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRL
CHHHHHHHCCCEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEE
ILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLGNLRKNSRGGFFITNNGNYIY
EEECCCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEE
DIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV
EEECCCCCCCCHHHHHHHHHHHCHHEEEEEEEEEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA