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The map label for this gene is infC [H]

Identifier: 89898050

GI number: 89898050

Start: 289189

End: 289749

Strand: Direct

Name: infC [H]

Synonym: CF0243

Alternate gene names: 89898050

Gene position: 289189-289749 (Clockwise)

Preceding gene: 89898047

Following gene: 89898051

Centisome position: 24.8

GC content: 39.39

Gene sequence:

>561_bases
GTGGCATTAAATTTAAAAATTAACAGGCAGATACGAGCTCCTAAAGTCCGTCTTATAGGTTCTTCTGGCGAACAATTGGG
CATACTGAATACAAAAGATGCTCTAGATTTAGCCAGAGAATCCGATTTAGATCTTGTGGAAGTTGCTTCTAACAGCGAGC
CACCTGTATGTAAAATTATGGATTATGGCAAATACCGCTATAATTTAACGAAAAAAGAAAAAGATTCTAAGAAAGCCCAG
CATCAGGTTCGTATTAAAGAAGTTAAGTTAAAGCCCAACATTGATGAGAATGACTTCTCCACAAAGCTAAAGCAGGCGCG
ATCTTTTATTGAGAAAGGTAATAAAGTAAAAATTACGTGTATGTTCCGAGGTCGTGAACTTGCTTACCCAGAACATGGGC
ACAAAGTTGTGCAAAAAATGAGTCAAGGTCTCGAAGACGTGGGATTCGTAGAATCCGAGCCAAAATTAAATGGCCGTTCC
TTAATTTGCGTAGTGGCTCCGGGGACGGTAAAAACCAAGAAAAAGCAGGACAAGTTCAATGCCCAAGATGAAAAGCAATA
A

Upstream 100 bases:

>100_bases
TCTAGGTGAGGGGAAGATTATTTCCATAGATTTTGCCCGAGGCAAGATACTAGCCTCTGATCATTTAAAGAATCGTGTTA
ACGAGCAATCGGGATAGAGT

Downstream 100 bases:

>100_bases
GTCCGTTGCGGCGCGTTTTAAGTTGACAGGTTCTGGTCAATTAAAAAGAACTCGCCCAGGGAAGAGGCATAAATTATCAA
AAAAATCTTCGCAGGAAAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MALNLKINRQIRAPKVRLIGSSGEQLGILNTKDALDLARESDLDLVEVASNSEPPVCKIMDYGKYRYNLTKKEKDSKKAQ
HQVRIKEVKLKPNIDENDFSTKLKQARSFIEKGNKVKITCMFRGRELAYPEHGHKVVQKMSQGLEDVGFVESEPKLNGRS
LICVVAPGTVKTKKKQDKFNAQDEKQ

Sequences:

>Translated_186_residues
MALNLKINRQIRAPKVRLIGSSGEQLGILNTKDALDLARESDLDLVEVASNSEPPVCKIMDYGKYRYNLTKKEKDSKKAQ
HQVRIKEVKLKPNIDENDFSTKLKQARSFIEKGNKVKITCMFRGRELAYPEHGHKVVQKMSQGLEDVGFVESEPKLNGRS
LICVVAPGTVKTKKKQDKFNAQDEKQ
>Mature_185_residues
ALNLKINRQIRAPKVRLIGSSGEQLGILNTKDALDLARESDLDLVEVASNSEPPVCKIMDYGKYRYNLTKKEKDSKKAQH
QVRIKEVKLKPNIDENDFSTKLKQARSFIEKGNKVKITCMFRGRELAYPEHGHKVVQKMSQGLEDVGFVESEPKLNGRSL
ICVVAPGTVKTKKKQDKFNAQDEKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=47.093023255814, Blast_Score=153, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21084; Mature: 20952

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNLKINRQIRAPKVRLIGSSGEQLGILNTKDALDLARESDLDLVEVASNSEPPVCKIM
CEEEEEECCCCCCCEEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEECCCCCCCEEEEE
DYGKYRYNLTKKEKDSKKAQHQVRIKEVKLKPNIDENDFSTKLKQARSFIEKGNKVKITC
ECCCEEEECCCCCHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGHKVVQKMSQGLEDVGFVESEPKLNGRSLICVVAPGTVKTKKKQDKFN
EECCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHCCC
AQDEKQ
CCCCCC
>Mature Secondary Structure 
ALNLKINRQIRAPKVRLIGSSGEQLGILNTKDALDLARESDLDLVEVASNSEPPVCKIM
EEEEEECCCCCCCEEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEECCCCCCCEEEEE
DYGKYRYNLTKKEKDSKKAQHQVRIKEVKLKPNIDENDFSTKLKQARSFIEKGNKVKITC
ECCCEEEECCCCCHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGHKVVQKMSQGLEDVGFVESEPKLNGRSLICVVAPGTVKTKKKQDKFN
EECCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHCCC
AQDEKQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]