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The map label for this gene is ddl [H]

Identifier: 89257158

GI number: 89257158

Start: 1843130

End: 1844020

Strand: Reverse

Name: ddl [H]

Synonym: FTL_1910

Alternate gene names: 89257158

Gene position: 1844020-1843130 (Counterclockwise)

Preceding gene: 89257159

Following gene: 89257157

Centisome position: 97.26

GC content: 37.71

Gene sequence:

>891_bases
ATGAAAAACGAAAAAATTGTTGTTTTATACGGTGGCGACTCTCCAGAAAGAGAAGTTTCTTTGAAATCTGGTAAAGCAGT
TTTGGATTCTTTAATAAGCCAAGGTTATGATGCCGTAGGTGTGGATGCTAGTGGTAAAGAGCTGGTAGCAAAACTTTTAG
AATTAAAGCCAGATAAGTGTTTTGTTGCATTACACGGTGAAGATGGTGAGAACGGTAGGGTGTCAGCATTACTTGAGATG
TTAGAAATCAAGCATACAAGCTCATCGATGAAATCATCTGTAATTACTATGGATAAAATGATCTCTAAAGAAATATTGAT
GCATCATCGGATGCCTACACCGATGGCAAAATTTCTTACTGATAAATTAGTTGCAGAAGATGAGATTAGCTTTCCTGCTG
CAGTTAAGCCAAGTAGTGGTGGTTCAAGTATTGCTACTTTTAAAGTGAAATCTATACAAGAGCTCAAACATGCCTATGAA
GAGGCATCGAAATACGGTGAGGTAATGATTGAACAATGGGTCACAGGTAAAGAAATTACAGTGGCTATTGTCAATGACGA
GGTTTATTCTTCTGTTTGGATTGAGCCACAAAATGAGTTTTATGATTATGAGTCAAAGTATAGTGGTAAATCAATCTATC
ATTCACCGAGTGGTTTATGCGAGCAAAAAGAACTTGAAGTTCGTCAATTAGCTAAAAAAGCTTACGATCTGCTTGGTTGT
AGCGGTCATGCAAGAGTAGACTTTATCTATGATGATAGGGGCAACTTTTACATTATGGAGATAAACTCTTCACCAGGAAT
GACCGATAATAGTCTATCGCCTAAGTCAGCAGCAGCAGAGGGGGTTGATTTTGATAGTTTTGTGAAGAGAATAATAGAAC
AGGCGCAATGA

Upstream 100 bases:

>100_bases
TAAGAATATTAACCATAATCTTGGAGTAACAGCTGGAGTAATGGCTGATGAATGTGGCAAACTGCTAAAAGATTTTTTTA
AACAAAGAAGAAATTAGATT

Downstream 100 bases:

>100_bases
CAAAAATTATCAAGAAGTTTCTAATATTGAGCTTGATACTGTTAGTAATCTTGGGATCGACTATTTTTGTTGCTGCTAAA
ACAGATAAGACAGTTTCAAA

Product: D-alanyl-alanine synthetase A

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKCFVALHGEDGENGRVSALLEM
LEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLTDKLVAEDEISFPAAVKPSSGGSSIATFKVKSIQELKHAYE
EASKYGEVMIEQWVTGKEITVAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGC
SGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ

Sequences:

>Translated_296_residues
MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKCFVALHGEDGENGRVSALLEM
LEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLTDKLVAEDEISFPAAVKPSSGGSSIATFKVKSIQELKHAYE
EASKYGEVMIEQWVTGKEITVAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGC
SGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ
>Mature_296_residues
MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKCFVALHGEDGENGRVSALLEM
LEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLTDKLVAEDEISFPAAVKPSSGGSSIATFKVKSIQELKHAYE
EASKYGEVMIEQWVTGKEITVAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGC
SGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786280, Length=306, Percent_Identity=41.1764705882353, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1786579, Length=353, Percent_Identity=28.0453257790368, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 32745; Mature: 32745

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50975 ATP_GRASP ; PS00843 DALA_DALA_LIGASE_1 ; PS00844 DALA_DALA_LIGASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKC
CCCCEEEEEECCCCCCCEEEHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEE
FVALHGEDGENGRVSALLEMLEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DKLVAEDEISFPAAVKPSSGGSSIATFKVKSIQELKHAYEEASKYGEVMIEQWVTGKEIT
HHHHCCCCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGC
EEEECCCHHHEEEECCCHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
SGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ
CCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKC
CCCCEEEEEECCCCCCCEEEHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEE
FVALHGEDGENGRVSALLEMLEIKHTSSSMKSSVITMDKMISKEILMHHRMPTPMAKFLT
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DKLVAEDEISFPAAVKPSSGGSSIATFKVKSIQELKHAYEEASKYGEVMIEQWVTGKEIT
HHHHCCCCCCCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGC
EEEECCCHHHEEEECCCHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
SGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ
CCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA