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The map label for this gene is gatA [H]

Identifier: 89257102

GI number: 89257102

Start: 1776180

End: 1777625

Strand: Reverse

Name: gatA [H]

Synonym: FTL_1842

Alternate gene names: 89257102

Gene position: 1777625-1776180 (Counterclockwise)

Preceding gene: 89257103

Following gene: 89257101

Centisome position: 93.76

GC content: 37.41

Gene sequence:

>1446_bases
ATGTCATATATTAAGAAATTAAGAGCTAGATTAGATAGTGGTGAAATAAGCGCTGTTGAACTAACTAAAGAGTATCTAGC
AAAAATTAAAGAGCAAGATAAGCGCATAAACTCTATAATCACTCTATGTGAAGCAGAAGCACTAAAAGAAGCAGAAGATG
CTGATGCTATTATTTCTGCAGGTAAGCAAGGATTATTAACAGGAATTCCTATTCTACATAAGGATCTTTTTTGCACTAAA
GGTATAAGAACTACGGCTGCCTCTAAGATGTTGGATAATTTCGTAGCACCATATGACTCAACAGTGACAAAAAACTGTAA
GGATCAAGGTATGGTCACTCTAGGCAAACTAAATATGGATGAGTTTGCTATGGGTTCAACTAACGAGTATAGCTATTATG
GAGCAGTTAGTAATCCTTGGGATTTAGAAAGAGTTCCGGGAGGTTCATCAGGTGGCTCAGCTGCAGCAGTTGCTGCAGGT
TTTGCGCCTATAAGTACAGGGTCAGATACTGGTGGATCGGTGAGACAGCCGGCTAGTTTTTGTGGTCTTACAGCAATGAA
GCCTAGTTATGGAAGTACTTCAAGGTTTGGCATGGTAGCGTTTGCATCATCTTTTGATCAAGCTGGTATTTTTGGACACT
ATGCTGAAGATGTCGCGATCATGTTAGATGCAATTGCTGGCGAGTGTGAGTTTGATTCTACTTGTGTTGGTGTTAAACAA
AATCATTTCACCCAAGATCTAGAAAAAGATATCTCTAGTAAAGTAATTGGCGTTGATGAGAGTCTAATCAAAGACCTACC
AGCACAAATACAAGAAGCAGTATCAAAAACTCTTGATAATTTCAAAAAGCTAGGTGCTGAAATAAAGTCGGTCAAGGTCC
CAGATTTAAAAGAAGCTCTTTCAACTTATTATATTATAACTCCAGCAGAAGCAGCAGCTAACTTAGCTAGATATGATGGT
ATTAGATATGGTTACCGTAATCCAGAAGCTAGAGATTTAGATGAATTATATAGAAAATCGCGAACAGATGGTTTTGGTGC
AGAAGTTAAGCGTAGAATTATGATTGGTAACTATGTCCTAGCATCGAGTCAGTATGATTCTTACTACAATAAGGCTCAGC
AGCTACGTAAGGTGATGACTGATCAAATTAATCAAATATTTACCCAAGTTGATGCTATCTTTATGCCAGCATCTCCAAGT
GAGGCATTTAAAAAAGGAGATAAGCTAGATCCTGTTTCGGCATATTTATCAGATATTTACACTATTCCTGCTAACATATC
AGGCCTACCAGCTATTGCTTTCCCAATTGGTTTTGCTAATAATTTACCAGTTGGTGGACAACTTATGGCTAAAGCATTTA
ATGATAATATCTTGACGCAGATGGTAGTGCAGTATCAAAAGCATTATGGTATTGAAGAATTTATTTTACAACAAGCGAGG
ATTTAA

Upstream 100 bases:

>100_bases
TCCCTCAAGATCAAGATAATCGTACAAGTTTTGATAAATTCGCTTGTGAAGTTGTTGATGATTACTTTATGGTGCCACAA
GTTGTTAAATAGGGTGAGCA

Downstream 100 bases:

>100_bases
TAGTGAATTGGGAAATGGTGATAGGGCTAGAAGTCCATATTCAATTAAGTACTAAATCTAAGCTATTTTCGACTTCTGCA
ACAAAGTATGGTCAACATCA

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISAGKQGLLTGIPILHKDLFCTK
GIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMDEFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAG
FAPISTGSDTGGSVRQPASFCGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQ
NHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEALSTYYIITPAEAAANLARYDG
IRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVLASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPS
EAFKKGDKLDPVSAYLSDIYTIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQAR
I

Sequences:

>Translated_481_residues
MSYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISAGKQGLLTGIPILHKDLFCTK
GIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMDEFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAG
FAPISTGSDTGGSVRQPASFCGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQ
NHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEALSTYYIITPAEAAANLARYDG
IRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVLASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPS
EAFKKGDKLDPVSAYLSDIYTIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQAR
I
>Mature_480_residues
SYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISAGKQGLLTGIPILHKDLFCTKG
IRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMDEFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAGF
APISTGSDTGGSVRQPASFCGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQN
HFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEALSTYYIITPAEAAANLARYDGI
RYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVLASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPSE
AFKKGDKLDPVSAYLSDIYTIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQARI

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=505, Percent_Identity=34.8514851485148, Blast_Score=285, Evalue=5e-77,
Organism=Homo sapiens, GI195972892, Length=503, Percent_Identity=28.6282306163022, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI166795287, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543272, Length=400, Percent_Identity=35.25, Blast_Score=234, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI17556264, Length=305, Percent_Identity=28.5245901639344, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17538252, Length=314, Percent_Identity=26.4331210191083, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17537465, Length=484, Percent_Identity=22.3140495867769, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990152, Length=199, Percent_Identity=31.6582914572864, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17556276, Length=309, Percent_Identity=27.5080906148867, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17556278, Length=309, Percent_Identity=27.5080906148867, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323950, Length=424, Percent_Identity=34.1981132075472, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6319685, Length=473, Percent_Identity=25.369978858351, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648113, Length=478, Percent_Identity=37.2384937238494, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24652985, Length=499, Percent_Identity=24.4488977955912, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19922090, Length=499, Percent_Identity=24.4488977955912, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24652981, Length=499, Percent_Identity=24.4488977955912, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24652983, Length=499, Percent_Identity=24.4488977955912, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24644968, Length=492, Percent_Identity=23.9837398373984, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI161078093, Length=500, Percent_Identity=24.8, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45550774, Length=496, Percent_Identity=23.7903225806452, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24648435, Length=496, Percent_Identity=23.7903225806452, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24648437, Length=496, Percent_Identity=23.7903225806452, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24648441, Length=427, Percent_Identity=23.6533957845433, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648439, Length=427, Percent_Identity=23.6533957845433, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356731, Length=485, Percent_Identity=21.4432989690722, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 52396; Mature: 52265

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISA
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKQGLLTGIPILHKDLFCTKGIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMD
CCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEECCCHH
EFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAGFAPISTGSDTGGSVRQPASF
HHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHH
CGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQ
HCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCHH
NHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEAL
HHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
STYYIITPAEAAANLARYDGIRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVL
HCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHEECCEEE
ASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPSEAFKKGDKLDPVSAYLSDIY
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCHHHHHHHHHH
TIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQAR
CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHC
I
C
>Mature Secondary Structure 
SYIKKLRARLDSGEISAVELTKEYLAKIKEQDKRINSIITLCEAEALKEAEDADAIISA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKQGLLTGIPILHKDLFCTKGIRTTAASKMLDNFVAPYDSTVTKNCKDQGMVTLGKLNMD
CCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEECCCHH
EFAMGSTNEYSYYGAVSNPWDLERVPGGSSGGSAAAVAAGFAPISTGSDTGGSVRQPASF
HHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHH
CGLTAMKPSYGSTSRFGMVAFASSFDQAGIFGHYAEDVAIMLDAIAGECEFDSTCVGVKQ
HCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCHH
NHFTQDLEKDISSKVIGVDESLIKDLPAQIQEAVSKTLDNFKKLGAEIKSVKVPDLKEAL
HHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
STYYIITPAEAAANLARYDGIRYGYRNPEARDLDELYRKSRTDGFGAEVKRRIMIGNYVL
HCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHEECCEEE
ASSQYDSYYNKAQQLRKVMTDQINQIFTQVDAIFMPASPSEAFKKGDKLDPVSAYLSDIY
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCHHHHHHHHHH
TIPANISGLPAIAFPIGFANNLPVGGQLMAKAFNDNILTQMVVQYQKHYGIEEFILQQAR
CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA