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The map label for this gene is fur [H]

Identifier: 89257091

GI number: 89257091

Start: 1764848

End: 1765270

Strand: Direct

Name: fur [H]

Synonym: FTL_1831

Alternate gene names: 89257091

Gene position: 1764848-1765270 (Clockwise)

Preceding gene: 89257076

Following gene: 89257092

Centisome position: 93.08

GC content: 32.86

Gene sequence:

>423_bases
ATGAACTCGAAAAACCTTGACTTAAAAGAATTCGGTTTTAAAGTTACTCAACCTCGTGTTGAGATACTTAAATTATTTGA
AAAAAACAAAGATAAGCATTTGAGTCCTGATGATGTTTTTTCTAAACTTAAAGCGCAAGGCAGCACAACAGGAATCGCTA
CAGTTTACAGAGTACTTAATCAGTTTGAGTCAGCAGGAATAATAAATCGCTTAAAACTTGATAATGAACAAGTAATGTAT
GAGTTAAATCAAGGTGAGCATCATGATCATATAATCTGTGTTAAGTGCAATATGATACAAGAGTTCTATAGCCCAGGAAT
CGAAGCTCTGCAAAAGCAGATTGTTGAATCATTCGGTGCTGAAATGATTGACTATAGTCTCAATATATATGTTAAATGCA
AATCCTGTCGTGAAAAAATATAA

Upstream 100 bases:

>100_bases
AAATATTTAATCATTAAAAACTCCTTATCTAAAACCTTTACATACTTATGCTTTTCGAATAATCTTTATATCAGAACTTA
TAAAACTATCTAATAGTAAA

Downstream 100 bases:

>100_bases
CGCAATAATCACTATCCAGAAGTATTTTAAAAAACCACTTTACAAATAAATACTTAAAGCAGCGCATACAATCTCACAAC
AGCTTTTCTGAAGTTTCTAA

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKAQGSTTGIATVYRVLNQFESAGIINRLKLDNEQVMY
ELNQGEHHDHIICVKCNMIQEFYSPGIEALQKQIVESFGAEMIDYSLNIYVKCKSCREKI

Sequences:

>Translated_140_residues
MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKAQGSTTGIATVYRVLNQFESAGIINRLKLDNEQVMY
ELNQGEHHDHIICVKCNMIQEFYSPGIEALQKQIVESFGAEMIDYSLNIYVKCKSCREKI
>Mature_140_residues
MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKAQGSTTGIATVYRVLNQFESAGIINRLKLDNEQVMY
ELNQGEHHDHIICVKCNMIQEFYSPGIEALQKQIVESFGAEMIDYSLNIYVKCKSCREKI

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=140, Percent_Identity=40.7142857142857, Blast_Score=121, Evalue=2e-29,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16147; Mature: 16147

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKAQGSTTGIATVYRVLN
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
QFESAGIINRLKLDNEQVMYELNQGEHHDHIICVKCNMIQEFYSPGIEALQKQIVESFGA
HHHHCCCHHHHCCCCHHHEEECCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHCH
EMIDYSLNIYVKCKSCREKI
HHHCCEEEEEEEEHHHHCCC
>Mature Secondary Structure
MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKAQGSTTGIATVYRVLN
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
QFESAGIINRLKLDNEQVMYELNQGEHHDHIICVKCNMIQEFYSPGIEALQKQIVESFGA
HHHHCCCHHHHCCCCHHHEEECCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHCH
EMIDYSLNIYVKCKSCREKI
HHHCCEEEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]