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The map label for this gene is nuoN

Identifier: 89257077

GI number: 89257077

Start: 1750154

End: 1751605

Strand: Reverse

Name: nuoN

Synonym: FTL_1817

Alternate gene names: 89257077

Gene position: 1751605-1750154 (Counterclockwise)

Preceding gene: 89257078

Following gene: 89257075

Centisome position: 92.38

GC content: 35.26

Gene sequence:

>1452_bases
ATGAGTTTATCAATCCTTTATATTTTGCCAGAAATACTACTAGCACTAGGTGTCATAGTTGTAATGTTTTCTGGACTTTT
TCTACATGGTAAGATTAGAAACATTAACTATATTTTTTTCCAAGTATTTACACTACTTGCTTTGATAGCAACTTTTGCTA
AAGAGTATCTGATACAGACTACTGGCTTAGTGTTTGAGGGTCAGGTTGTATTTAGTGGCTTTGCATATACATTACAACTA
GTAATACTTGTCTTAGCAGTCTTTGTTGCATTATATTCAAGAGATTATGTCAAAGATAGAAAAATATCAGATGGTGATTT
CTATACATTGTTAATGCTATGCGTACTTGGTGCAATGGTTTTAACAGCGGCACATAGTTTAGTTACAATATATGTTGGTC
TAGAGTTATTATCATTACCAATGTATGCATTGATCGCAATCTATAGAGATTCAGGCAAAGGTCTTGAGGCCGCGATCAAA
TACTTTGTTTTAGGGGCTATTGCATCGGCTCTACTATTATTTGGGATGTCATTTGTCTATGGAATGACAGGCAAGCTTGA
TATTACAGAAATAGCCAATGTATTAGCACATGGTAACTTCGCAGGCTTACAGCAGCAGTTTTTGCTTGTATACTTGGTAA
TGATGATCGCTACATTTTTATTCAAACTTGGTGCTTTCCCTTTTCATATGTGGTTACCAGATGTTTATCAAGGTGCTCCA
AACGCAGTAGCAAATATCGTTGCAACTATTCCAAAAGTTGCTGCCTTTGCGATGCTTGTGAATATCTTATTTGTTGGCTT
CCCATCACTAAAAGATTCATGGATATATCTGTTTAGGATTATAGGTATATTGTCAATATTTTTTGGTAGCTTGGTGGCAC
TCTCACAGACTAATGTTAAACGACTTTTGGGTTACTCAACAGTTTCACAGATTGGTTTTGTGCTATTGGCAACAACATTA
AATCCTCAAGGATATGCCTTAACTGCGGCAAGCTTCTATGTCATAGTGTATTTATTTACAACTTTAGCTGTATTTGGCGT
ACTTACAACTATTTCTGTCGGGGGATATGAAGTTCAGGATCTTAATGACTTAAAAGGTTTCAACACAAAAGATTCATGGT
TAGCATTTATCTTGTTGATTGTGCTATTTTCAATGGCGGGTATCCCTCCATTTGGTGGCTTTATTGCTAAACTATTTGTA
GTTATGGGATTAATTAATGATGGTAATTACTTCTTGGCGTGTTTTGTACTATTTATGGCAGTAATAGCATCATTCTACTA
TGTGCGTGTCATCAAAACCATGTACTTTGATGATCCTGATAATGATGAAACTGTTAAGCCACCGTTGACATCTCTAATAG
CATTAAGTATTAACGGTTTGGTACTATTATTCTTAGGGATTATGCCAATGCTCCTTTTGGGAGTTCTTACCCAAGTTACT
AATGTTATATAA

Upstream 100 bases:

>100_bases
GATTTTATTGTTTGGTTTCTATCCAGAGCCAATTTTGCAGCTATCAGCAGCAGCATCGGCACATATTGTTGGTCTATCTC
TATAAGGTGGTGTTTTGATT

Downstream 100 bases:

>100_bases
AAACTAATAGTTTATTGCCTATTGTCATTATTACTTTTATACTTTTATCTAGAAACAATTAAATTTTATTAGCTGATGAA
GGAAATTCTAGGACCGCTTA

Product: NADH dehydrogenase I, N subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGLVFEGQVVFSGFAYTLQL
VILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIK
YFVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVYLVMMIATFLFKLGAFPFHMWLPDVYQGAP
NAVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTL
NPQGYALTAASFYVIVYLFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFV
VMGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVT
NVI

Sequences:

>Translated_483_residues
MSLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGLVFEGQVVFSGFAYTLQL
VILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIK
YFVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVYLVMMIATFLFKLGAFPFHMWLPDVYQGAP
NAVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTL
NPQGYALTAASFYVIVYLFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFV
VMGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVT
NVI
>Mature_482_residues
SLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGLVFEGQVVFSGFAYTLQLV
ILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIKY
FVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVYLVMMIATFLFKLGAFPFHMWLPDVYQGAPN
AVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTLN
PQGYALTAASFYVIVYLFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFVV
MGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVTN
VI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI145693160, Length=480, Percent_Identity=30.4166666666667, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1788614, Length=425, Percent_Identity=25.1764705882353, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788613, Length=317, Percent_Identity=25.8675078864353, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788827, Length=330, Percent_Identity=26.0606060606061, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788831, Length=320, Percent_Identity=25.3125, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788829, Length=385, Percent_Identity=24.1558441558442, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_FRATF (A7NEJ7)

Other databases:

- EMBL:   CP000803
- RefSeq:   YP_001429356.2
- STRING:   A7NEJ7
- GeneID:   5523885
- GenomeReviews:   CP000803_GR
- KEGG:   fta:FTA_1925
- HOGENOM:   HBG747830
- OMA:   SIGHIGF
- ProtClustDB:   CLSK986248
- BioCyc:   FTUL458234:FTA_1925-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 53082; Mature: 52951

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfef5b50)-; HASH(0x125e1c60)-; HASH(0x125a87d8)-; HASH(0x121d36e4)-; HASH(0x125cdcb8)-; HASH(0x101acc68)-; HASH(0x10c1130c)-; HASH(0x11bf8544)-; HASH(0xf3debdc)-; HASH(0x11cf24ac)-; HASH(0x124452a0)-; HASH(0x12a26ff0)-; HASH(0x12251d04)-; HASH(0x126c9004)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCH
>Mature Secondary Structure 
SLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQT
CCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH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HCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA