Click here to switch to the map view.

The map label for this gene is atpB [H]

Identifier: 89257064

GI number: 89257064

Start: 1733931

End: 1734722

Strand: Reverse

Name: atpB [H]

Synonym: FTL_1801

Alternate gene names: 89257064

Gene position: 1734722-1733931 (Counterclockwise)

Preceding gene: 89257065

Following gene: 89257063

Centisome position: 91.49

GC content: 37.12

Gene sequence:

>792_bases
ATGGCAAATACAGAAGCAGGCTCTCAAGTAGCTACTGAATATGTGCAGCACCACTTGCATCACTGGCAAGTAAGTTTAGG
TCAAGGTTCTTTTTGGCAGCTTAATGTTGATTCATTATTGGTGAGTGGCATATTAGGGGTTGTATTTATATTGGCTATGT
TTTTGGCAGCGAGAAAAGCTAACTCAGGAGTTCCAGGCAAGTTTCAGAATATGATTGAGGCTGTTTGGGAATGGATGGAT
GGCATGGTTGCTAATAATTACCGTCATAAAAGAGATTTTGTTACACCACTAGCACTTACTATATTTGTTTGGGTAGTGTT
GATGAATTTTATGGATTTGCTCCCAGTTGATCTTTTCGGTTGGATAATTAGCTTCTTTACTGCTAGTCATGAAGCTTATT
TTAGAGTTGTTCCTACTGCTGATCCTAATGTTACTTTTGCTATGTCAATAGCAGTTTTCTTCCTTGTGATTTTTTATAAT
CTCAAGGCAAAAGGCTTTGGGTTGATCAAAGAAGTGCTAAGCTCACCTTTTGGTATTTGGTTATTTCCTTTAAATATCTT
TTTTAGACTGGTTGATGAAATAGTTAAGCCAGTTTCACTGTCGCTGCGTTTGTTTGGTAATATTTTTGCGGGAGAACTTA
TATTTATCCTTATAGCTTTATTGCCGTGGTGGTTTCAGTGGACTCTTGGTGGGATATGGGCAATATTCCATATCCTAATT
GTTTTGATACAGGCTTTTGTATTTATGATGCTAACTGTAGTTTATTTAAATATGGCGCAGGAAGCTCACTAA

Upstream 100 bases:

>100_bases
CAATTAGCAGTGTGTTTTGTGCCTATATTGTTCAAAAGGGTCAGATAGGTTTATTTGGGTGTTTATATAAAAGTAGATAA
TATACTGGTGGAATAAAATA

Downstream 100 bases:

>100_bases
GTTTAAACTAACTTAAAAATAAATCTTTAATAAAACAGGAGAAATAAAAAATGGATATGTCTTTACAAGTTTTAGGGAAC
TTAAATGGTTTGACAGCAGT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MANTEAGSQVATEYVQHHLHHWQVSLGQGSFWQLNVDSLLVSGILGVVFILAMFLAARKANSGVPGKFQNMIEAVWEWMD
GMVANNYRHKRDFVTPLALTIFVWVVLMNFMDLLPVDLFGWIISFFTASHEAYFRVVPTADPNVTFAMSIAVFFLVIFYN
LKAKGFGLIKEVLSSPFGIWLFPLNIFFRLVDEIVKPVSLSLRLFGNIFAGELIFILIALLPWWFQWTLGGIWAIFHILI
VLIQAFVFMMLTVVYLNMAQEAH

Sequences:

>Translated_263_residues
MANTEAGSQVATEYVQHHLHHWQVSLGQGSFWQLNVDSLLVSGILGVVFILAMFLAARKANSGVPGKFQNMIEAVWEWMD
GMVANNYRHKRDFVTPLALTIFVWVVLMNFMDLLPVDLFGWIISFFTASHEAYFRVVPTADPNVTFAMSIAVFFLVIFYN
LKAKGFGLIKEVLSSPFGIWLFPLNIFFRLVDEIVKPVSLSLRLFGNIFAGELIFILIALLPWWFQWTLGGIWAIFHILI
VLIQAFVFMMLTVVYLNMAQEAH
>Mature_262_residues
ANTEAGSQVATEYVQHHLHHWQVSLGQGSFWQLNVDSLLVSGILGVVFILAMFLAARKANSGVPGKFQNMIEAVWEWMDG
MVANNYRHKRDFVTPLALTIFVWVVLMNFMDLLPVDLFGWIISFFTASHEAYFRVVPTADPNVTFAMSIAVFFLVIFYNL
KAKGFGLIKEVLSSPFGIWLFPLNIFFRLVDEIVKPVSLSLRLFGNIFAGELIFILIALLPWWFQWTLGGIWAIFHILIV
LIQAFVFMMLTVVYLNMAQEAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=267, Percent_Identity=50.561797752809, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 30000; Mature: 29869

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTEAGSQVATEYVQHHLHHWQVSLGQGSFWQLNVDSLLVSGILGVVFILAMFLAARKA
CCCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
NSGVPGKFQNMIEAVWEWMDGMVANNYRHKRDFVTPLALTIFVWVVLMNFMDLLPVDLFG
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIISFFTASHEAYFRVVPTADPNVTFAMSIAVFFLVIFYNLKAKGFGLIKEVLSSPFGIW
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
LFPLNIFFRLVDEIVKPVSLSLRLFGNIFAGELIFILIALLPWWFQWTLGGIWAIFHILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIQAFVFMMLTVVYLNMAQEAH
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANTEAGSQVATEYVQHHLHHWQVSLGQGSFWQLNVDSLLVSGILGVVFILAMFLAARKA
CCCCCHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
NSGVPGKFQNMIEAVWEWMDGMVANNYRHKRDFVTPLALTIFVWVVLMNFMDLLPVDLFG
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIISFFTASHEAYFRVVPTADPNVTFAMSIAVFFLVIFYNLKAKGFGLIKEVLSSPFGIW
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
LFPLNIFFRLVDEIVKPVSLSLRLFGNIFAGELIFILIALLPWWFQWTLGGIWAIFHILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIQAFVFMMLTVVYLNMAQEAH
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA