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The map label for this gene is atpA [H]

Identifier: 89257060

GI number: 89257060

Start: 1730955

End: 1732496

Strand: Reverse

Name: atpA [H]

Synonym: FTL_1797

Alternate gene names: 89257060

Gene position: 1732496-1730955 (Counterclockwise)

Preceding gene: 89257061

Following gene: 89257059

Centisome position: 91.38

GC content: 38.2

Gene sequence:

>1542_bases
ATGCAATTAAGTCCATCAGAAATAAGTGGTTTAATAAAACAAAGAATCGAGAAGTTTGACAATTCAGTTGAACTAAAATC
AGAAGGTACAATCGTCAGTGTTGCTGATGGTATCGTTACTATTTATGGATTAAATGATGTTACTGCTGGTGAAATGATTA
AATTACCAGGCGATGTTTATGGTCTAGCTCTGAACTTAAATACAGATTCGGTTGGTGCTGTAGTTTTAGGGGATTATGAG
CATATTAAAGAAGGCGATAAAGCATACTGTACTGGTAGAATACTAGAAGTCCCAGTTGGAGAGGCTCTCTTAGGCAGAGT
TGTTGATGCTTTAGGTAATCCTATCGATGGTAAGGGTGAAGTGGCAACTGATTTAACTTCACCTATCGAAAAAATTGCTC
CAGGTGTTATTTGGAGAAAATCAGTAGATCAAGCGCTACAAACAGGTATTAAGTCAATTGACTCAATGGTACCAATTGGT
AGAGGTCAAAGAGAGCTTATCATTGGAGATAGACAGATAGGTAAAACTGCAATTGCTGTTGATACGATTATTAACCAAAA
GGGTACAGGTGTTAAGTGTATCTATGTTGCTATTGGTCAGAAGGCATCTACAATTGCAAACATTGTAAGACAGCTTGAAG
AGTATGGCGCAATGGAACATACAATTATTGTTGCAGCTACAGCATCTGATTCTGCAGCGCTGCAATATATCGCGCCTTAT
GCGGGATGTTCTATGGGTGAATACTTTAGGGATCGCGGTCAAGATGCACTTATTGTTTATGATGATTTGACTAAACAAGC
ATGGGCTTATAGACAGATTTCACTTTTATTAAGAAGACCGCCTGGACGTGAAGCTTATCCTGGTGATGTATTCTATCTTC
ACTCTAGACTTCTTGAAAGAGCTGCAAGAGTCAACGAAGAATATGTCGAGAAATTTACAAATGGTGAAGTGAAAGGTAAG
ACAGGTTCTTTGACTGCACTACCTATCATTGAAACACAAGCTGGTGATATCTCTGCATTCGTTCCAACGAACGTTATATC
AATCACTGACGGGCAGATATTCTTAGAGACAGATTTATTTAACTCTGGCTTAAGACCTGCGATAAACCCTGGTAACTCTG
TTTCACGTGTCGGTGGTGCAGCACAAACTAAGATTATCAAGAAACTTGGTGGTGGTATCCGTTTGGCACTTGCGCAATAT
AGGGAGCTAGAGGCGTTCTCACAATTTGCATCAGACTTGGATGAAGCAACTCGTGCACAATTAAATAGAGGTCAAAGAGT
AACAGAATTGCTAAAACAAAAGCAATTCTCAACTTTATCTGTGGCTTTAATGGCATTGTCACTTTATGCTGCTGATAATG
GATACTTAGATAACTTAGAGGTTTCAGAGGTTATACCTTTTGAATCTGCGCTACATGCATTAGCAGAAACAAAGTATAGT
GATGTAATTGCAGAAATTAATGAAACTGATAAGTATGATGCTGATATTGCTGATAAGTTAAAAATTATTGTTGAAGACTG
TAAAGCAAATCAAGCTTGGTAA

Upstream 100 bases:

>100_bases
AGTAGTCAAGGTTGGGGATACAGTTATTGATAGTTCAGTATCTGGTCATTTAGAGAAATTAAAAAGTATTTTGTTATCAT
AAATTATAGGAAGTGAGCTT

Downstream 100 bases:

>100_bases
TAGGAGTATAGACTATGTCTAACGCTAGAGAAATACGTTCCAAAGTACAGAGTGTTAAAAACACGCAAAAAATCACAGGT
GCAATGGAATTAGTTGCTGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETDKYDADIADKLKIIVEDCKANQAW

Sequences:

>Translated_513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETDKYDADIADKLKIIVEDCKANQAW
>Mature_513_residues
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYE
HIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIG
RGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPY
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGK
TGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQY
RELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
DVIAEINETDKYDADIADKLKIIVEDCKANQAW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=512, Percent_Identity=56.640625, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI4757810, Length=512, Percent_Identity=56.640625, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI19913428, Length=316, Percent_Identity=29.1139240506329, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=390, Percent_Identity=23.5897435897436, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913426, Length=319, Percent_Identity=27.8996865203762, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913424, Length=256, Percent_Identity=26.953125, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=70.7602339181287, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=377, Percent_Identity=24.1379310344828, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788251, Length=382, Percent_Identity=26.1780104712042, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=509, Percent_Identity=55.4027504911591, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=509, Percent_Identity=55.4027504911591, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=509, Percent_Identity=51.4734774066798, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17570191, Length=311, Percent_Identity=29.2604501607717, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=310, Percent_Identity=27.4193548387097, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=384, Percent_Identity=23.1770833333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=256, Percent_Identity=26.5625, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=87, Percent_Identity=35.632183908046, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319370, Length=514, Percent_Identity=52.5291828793774, Blast_Score=545, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6319603, Length=310, Percent_Identity=30.3225806451613, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=330, Percent_Identity=26.0606060606061, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24658560, Length=471, Percent_Identity=57.9617834394904, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.7955271565495, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.7955271565495, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.7955271565495, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638766, Length=392, Percent_Identity=24.234693877551, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=26.1682242990654, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24583988, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583986, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583984, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583992, Length=256, Percent_Identity=27.734375, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=27.2, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55537; Mature: 55537

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVY
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCEEECCCCEE
GLALNLNTDSVGAVVLGDYEHIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGE
EEEEEECCCCCCEEEECCHHHHCCCCCEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCC
VATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHH
DTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHH
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQ
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DVIAEINETDKYDADIADKLKIIVEDCKANQAW
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVY
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCCCCCEEECCCCEE
GLALNLNTDSVGAVVLGDYEHIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGE
EEEEEECCCCCCEEEECCHHHHCCCCCEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCC
VATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHH
DTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHH
AGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQ
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DVIAEINETDKYDADIADKLKIIVEDCKANQAW
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA